Search clinical trials for: Oxycodone or morphine sulfate immediate release (MSIR)

Total 82 results

Brigham and Women's Hospital
National Institute on Drug Abuse (NIDA); Arthritis Foundation

Completed

Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms

Depression | Anxiety | Degenerative Disc Disease | Chronic Low Back Pain

United States
Brigham and Women's Hospital
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back Pain

Low Back Pain

United States
University Health Network, Toronto
Canadian Society of Hospital Pharmacists

Withdrawn

Dosing Intervals of Opioid Medication for Chronic Pain

Chronic Pain

Canada
Tetra Bio-Pharma
Cognitive Research Corporation

Recruiting

Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain (REBORN)

Cancer | Breakthrough Cancer Pain

United States
QRxPharma Inc.

Completed

Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients

Postoperative Pain

United States
Ensysce Biosciences
Dr. Vince Clinical Research

Completed

A Study to Evaluate the Oral Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Recreational Drug Use

United States
QRxPharma Inc.

Completed

Double Blind Efficacy and Safety Study of Flexible-Dose vs Low-Dose Q8003 After Undergoing Primary Unilateral Total Knee Arthroplasty

Postoperative Pain

United States
Pfizer

Completed

A Randomized, Two-way, Crossover Study to Estimate the Relative Bioavailability of a Controlled-release Formulation of Oxycodone (40 mg) With Sequestered Naltrexone Compared With Immediate-release Oxycodone Tablets (20 mg) in Healthy Volunteers

Healthy

United States
QRxPharma Inc.

Completed

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Postoperative Pain

United States
QRxPharma Inc.

Completed

Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip Arthroplasty

Postoperative Pain

United States
University of Rochester

Terminated

Open-Label Trial Comparing Oxycodone Medications (OUTCOMES)

Chronic Pain

United States
Member Companies of the Opioid PMR Consortium

Terminated

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Opioid-Related Disorders | Drug Abuse | Opiate Addiction | Narcotic Abuse

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States
BioDelivery Sciences International

Completed

Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film

Pain

United States
Wayne State University

Recruiting

Cannabidiol, Morphine, Pain (CMP)

Chronic Pain | CBD

United States
Mundipharma Korea Ltd

Completed

An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion. (SWITCH)

Cancer Pain

Korea, Republic of
QRxPharma Inc.

Completed

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Moderate to Severe Postoperative Pain

United States
Antonios Likourezos

Withdrawn

A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the ED

Pain

United States
QRxPharma Inc.

Completed

Efficacy and Safety of Q8003 in the Management of Post-bunionectomy Pain

Postoperative Pain

United States
Actavis Inc.

Completed

Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults

Healthy

United States
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200 mg Capsule With Two 100 mg KADIAN Capsules on Applesauce

Healthy

United States
Icahn School of Medicine at Mount Sinai
U.S. Department of Education

Completed

Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury

Neuropathic Pain | Spinal Cord Injury

United States
Actavis Inc.

Completed

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fed Conditions

Healthy

United States
Actavis Inc.

Completed

Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fasted Conditions

Healthy

United States
Ensysce Biosciences

Completed

A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Recreational Drug Use

United States
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Completed

Prescription Opioid Effects in Abusers Versus Non-Abusers

Substance-Related Disorders | Opioid-Related Disorders

United States
Pacira Pharmaceuticals, Inc
Registrat-Mapi

Terminated

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 (IMPROVE-Open)

Bowel Obstruction

United States
Pfizer

Completed

Study to Determine the Bioavailability, Pharmacodynamic Effects, and Safety of Whole and Crushed ALO-01 Compared to Morphine Sulfate Immediate Release (MSIR)

Healthy

Canada
Javelin Pharmaceuticals

Completed

Efficacy and Safety of Intranasal Morphine for Pain After Third Molar Extraction

Post-Operative Pain | Third Molar Extraction
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

Oxycodone User Registry (OUR)

Pain
Purdue Pharma LP

Terminated

Safety and Efficacy of Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Low Back Pain

Back Pain Lower Back Chronic

United States
Purdue Pharma LP

Terminated

Safety and Efficacy of Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Osteoarthritis Pain

Osteoarthritis

United States
Hospital Central Dr. Luis Ortega

Completed

Oxycodone Extended-release in the Treatment of Perioperative Pain in Patients Undergoing Orthopaedic Surgery

Surgery

Venezuela
Centre Hospitalier Universitaire de Nīmes

Unknown

Multimodal Analgesia Strategies After Major Shoulder Ambulatory Surgery (Shoulder1)

Tendon Injuries

France
Archimedes Development Ltd

Completed

Efficacy and Safety Study of Nasalfent for Treatment of Breakthrough Cancer Pain in Patients Taking Regular Opioids

Cancers, Pain

United Kingdom
Pfizer

Completed

Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking Avinza (ACCESS 2008)

Pain

United States, Puerto Rico
Pfizer

Completed

Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users

Nondependent Opioid Abuse, Episodic

United States
Vital 5, LLC

Withdrawn

Clinical Evaluation of the ReLeaf Analgesic Infusion Catheter & Wound Drain

Low Back Pain
Antonios Likourezos

Completed

Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)

Pain Management

United States
Cephalon

Completed

Fentanyl Buccal Tablets Versus Immediate Release Oxycodone for Breakthrough Pain in Patients With Chronic Pain

Chronic Pain

United States
Cephalon

Completed

Efficacy and Safety of Fentanyl Buccal Tablets Compared With Oxycodone for the Management of Break Through Pain

Chronic Pain

United States
Pacira Pharmaceuticals, Inc
Registrat-Mapi

Terminated

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 (IMPROVE-Open)

Bowel Obstruction

United States
Pacira Pharmaceuticals, Inc
Registrat-Mapi

Completed

Adult Patients Undergoing Open Colectomy MA402S23B303 (IMPROVE-Open)

Bowel Obstruction

United States
Mayo Clinic

Completed

Non-intrusive Detection of Temporary Neurologic Impairment By Opioids

Healthy

United States
University of Cologne
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Fentanyl Buccal Tablet for the Relief of Episodic Breathlessness in Cancer Patients (EFFENDYS)

Cancer | Dyspnea, Paroxysmal

Germany
Fujian Cancer Hospital

Not yet recruiting

IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration

Cancer Pain

China
Mundipharma (China) Pharmaceutical Co. Ltd

Unknown

A Study to Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer Pain

Cancer Pain

China
Labtec GmbH

Withdrawn

A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to Cancer

Chronic Pain
Hopital Lariboisière

Unknown

Sustained-release Morphine Pharmacokinetics in Roux-en-Y Gastric Bypass Subjects (OBEMO2)

Bypass Complications

France

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