Search clinical trials for: oxycodone-naloxone

Total 759 results

Mundipharma Research GmbH & Co KG

Completed

OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects

Chronic Osteoarthritis

Spain, Belgium, Finland, Czechia, Germany, Hungary
Mundipharma Research GmbH & Co KG

Completed

A Randomised, Double Blind, Placebo and Active Controlled, Double Dummy,Parallel Group Study to Determine the Safety and Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Subjects With Moderate to Severe, Chronic Nonmalignant Pain

Subjects With Moderate to Severe, Chronic Nonmalignant Pain
Mundipharma SAS

Terminated

Efficacy of Oxycodone/Naloxone(OXN), Versus Oxycodone (OXY), for the Reduction of Intensity of Opioid-induced Constipation in Pain Patients (OXN3505)

Pain | Constipation

France
Mario Negri Institute for Pharmacological Research

Completed

GREAT - Good Response With Appropriate Treatment

Neoplasms | Cancer Pain

Italy
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy

Pain | Constipation

United Kingdom
Purdue Pharma LP

Completed

Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain

Low Back Pain

United States, Poland, Czech Republic, Italy
Ullevaal University Hospital
Mundipharma AB

Completed

A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy

Postoperative Pain | Opioid Induced Constipation

Norway
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Mundipharma Research GmbH & Co KG

Completed

A Study Comparing Oxycodone to Oxycodone/Naloxone in Moderate to Severe, Chronic Cancer Pain

Pain | Cancer | Constipation

United Kingdom
Kuopio University Hospital

Completed

Opioid Induced Bowel Dysfunction in Patients Undergoing Spinal Surgery (oksineukir)

Constipation

Finland
Mundipharma (China) Pharmaceutical Co. Ltd

Completed

Targin for Non-cancer Pain

Non Cancer Pain

China
Mundipharma Korea Ltd

Completed

A Study to Evaluate Efficacy and Safety of Oxycodone/Naloxone Compared to OxyContin in Korean Cancer Patients (TOP)

Cancer

Korea, Republic of
Mundipharma Korea Ltd

Completed

An Interventional Study to Compare the Efficacy and Tolerability With Targin® in Non-malignant Chronic Pain (GLORY)

Chronic Pain

Korea, Republic of
Mundipharma Pharmaceuticals B.V.

Completed

Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain

Pain

Belgium
Mundipharma Research GmbH & Co KG

Completed

Oxycodone-naloxone Prolonged Release Tablets in Relieving Opioid-related Constipation

Pain
Kuopio University Hospital
Admescope Ltd

Active, not recruiting

Opioid Induced Bowel Dysfunction in Patients Undergoing Cesarean Section (oksisektio)

Pain, Postoperative | Constipation

Finland
Mundipharma Korea Ltd

Completed

PROspective Non-interventional Open laBEl Trial for TARGIN in Korean Patients With Cancer Pain (PROBE)

Cancer

Korea, Republic of
Mundipharma Korea Ltd

Completed

An Interventional Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Spinal Disorders (TALENT)

Spinal Disorders
Mundipharma (China) Pharmaceutical Co. Ltd

Completed

Determine the Safety and Efficacy of Oxy/Nal Tablets Compared to Oxy PR in Subjects With Cancer Pain

Pain | Cancer

China
University of Edinburgh

Completed

A Comparison of Targinact vs. Oxycodone on Gut Function After Colorectal Surgery (TACS)

Postoperative Pain | Postoperative Nausea and Vomiting

United Kingdom
Mundipharma CVA

Completed

A Non-interventional, Observational Study for Targinact® Treatment in Patients With Severe Pain.

Severe Pain

Belgium
Kati Järvelä

Completed

A Comparison of PR Oxycodone/Naloxone and PR Oxycodone After Cardiac Surgery

Postoperative Pain | Opioid Related Disorders

Finland
Mundipharma Research GmbH & Co KG

Completed

OXN PR vs Placebo in Opioid-naive Subjects Suffering From Severe Pain Due to Bladder Pain Syndrome (BPS)

Pain | Interstitial Cystitis | Painful Bladder Syndrome

Poland, Germany, Hungary, Czechia, United Kingdom
Purdue Pharma LP

Completed

Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
Mundipharma CVA

Completed

A Non-interventional, Observational Study for Targinact® Treatment in Patients With Chronic Severe Pain

Chronic Severe Pain

Belgium
University of British Columbia
Vancouver Coastal Health; International Collaboration on Repair Discoveries; Purdue...

Completed

Targin® for Chronic Pain Management in Patients With Spinal Cord Injury

Chronic Pain

Canada
Mundipharma Research GmbH & Co KG

Completed

A Randomised Placebo Controlled Study of OXN PR for Severe Parkinson's Disease Associated Pain

Parkinson's Disease With Severe Pain

United Kingdom, Spain, Germany, Hungary, Czech Republic, Poland, Romania
Mundipharma Research GmbH & Co KG

Completed

Oxycodone/Naloxone Prolonged Release (OXN PR) Compared to Placebo to Demonstrate Improvement in Symptoms of Restless Legs Syndrome (RLS) in Subjects With Moderate to Severe Idiopathic RLS With Daytime Symptoms

Moderate to Severe Idiopathic RLS With Daytime Symptoms

Spain, Sweden, Germany
Mundipharma Korea Ltd

Completed

A Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Cancer

Korea, Republic of
Mundipharma Pharmaceuticals B.V.

Completed

Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain

Pain

Netherlands
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy

Moderate to Severe Pain Due to Diabetic Polyneuropathy

Germany
University Hospital Inselspital, Berne

Completed

Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia

Epidural Analgesia | Radical Cystectomy | Postoperative Pain Management | Oral Oxycodone With/Without Naloxone | Return of the Bowel Function

Switzerland
Mundipharma Oy

Completed

OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty (OXN4505)

Post Operative Pain

Finland
Kuopio University Hospital
Admescope Ltd

Active, not recruiting

The Safety and Efficacy of Epidural Oxycodone (epioksipanu)

Pain, Postoperative

Finland
Mundipharma CVA

Unknown

A Non-interventional, Observational Study for Quality of Life (Overall Health Assessment) in Patients With Chronic Severe Pain During Targinact® Treatment

Chronic Severe Pain

Belgium
IRCCS Policlinico S. Matteo

Withdrawn

Treatment of Chronic Pain From Osteoarthritis

Chronic Pain

Italy
Kuopio University Hospital
Admescope Ltd

Recruiting

Oxycodone in Treatment of Early Labour Pain Efficacy and Safety (oksisynnytys)

Labor Pain

Finland
Napp Pharmaceuticals Limited

Completed

A Study to Compare Oxycodone/Naloxone Prolonged Release Against Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Low Back Pain or Pain Due to Osteoarthritis

Osteoarthritis | Back Pain

United Kingdom
Ensysce Biosciences
Dr. Vince Clinical Research

Completed

A Study to Evaluate the Oral Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Recreational Drug Use

United States
Mundipharma Research GmbH & Co KG

Completed

Oxycodone-naloxone in Relieving Opioid-related Constipation

Pain
Samjin Pharmaceutical Co., Ltd.

Completed

A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke

Stroke, Acute

Korea, Republic of
Grünenthal GmbH

Completed

Tapentadol Prolonged Release (PR) Versus Oxycodone/Naloxone Prolonged Release in Severe Chronic Low Back Pain With a Neuropathic Component.

Back Pain | Low Back Pain | Neuropathic Pain

Germany, Spain, Austria, Italy
Mallinckrodt

Completed

Fasting Study of Oxycodone Hydrochloride 15 mg Tablets and Roxicodone™ 15 mg Tablets

Healthy

United States
Mundipharma Research GmbH & Co KG

Completed

To Demonstrate Equivalence in Analgesic Efficacy & Bowel Function Between OXN PR Higher Dose & Lower Dose Tablet Strengths in Subjects With Non-cancer or Cancer Pain

Non-malignant Pain | Malignant Pain

Germany
Mallinckrodt

Completed

Fasting Study of Oxycodone Hydrochloride 30 mg Tablets and Roxicodone™ 30 mg Tablets

Healthy

United States
Mallinckrodt

Completed

Fed Study of Oxycodone Hydrochloride 30 mg Tablets and Roxicodone™ 30 mg Tablets

Healthy

United States
Judith Feinberg

Unknown

Nasal Naloxone for Narcotic Overdose

Drug Overdose

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States
Pfizer

Completed

A Randomized, Two-way, Crossover Study to Estimate the Relative Bioavailability of a Controlled-release Formulation of Oxycodone (40 mg) With Sequestered Naltrexone Compared With Immediate-release Oxycodone Tablets (20 mg) in Healthy Volunteers

Healthy

United States
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark

3

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