Search clinical trials for: P-321 Ophthalmic Solution placebo

Total 7300 results

Alcon Research
Novartis Institutes for BioMedical Research

Withdrawn

A Study of the Safety and Tolerability of Intravitreal LKA651 in Patients With Diabetic Macular Edema

Diabetic Macular Edema
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Completed

Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease

Dry Eye

China
Santen Pharmaceutical Co., Ltd.

Completed

Study of DE-114 Ophthalmic Solution in Patients With Allergic Conjunctivitis

Allergic Conjunctivitis

Japan
Santen Inc.

Completed

Ocular Availability in Human Tears After Topical Administration of 1.5% Levofloxacin Compared to Active Comparators

Healthy

United States
Shire

Completed

A Study to Evaluate Efficacy and Safety of Lifitegrast in Subjects With Dry Eye (OPUS-3) (OPUS-3)

Dry Eye Disease

United States
Alcon Research

Completed

Systane Hydration in Subjects Undergoing Cataract Surgery

Cataract | Dry Eye Disease

Spain
Alcon Research

Terminated

A Multicenter Study of the Pigmentation in the Trabecular Meshwork After Two Years of Treatment With TRAVATAN 0.004% Ophthalmic Solution

Open-angle Glaucoma
Synphora AB

Unknown

Latanoprost for the Treatment of Menière's Disease

Menière's Disease

Sweden
Faes Farma, S.A.
ORA, Inc.

Completed

A Study Evaluating Bilastine Ophthalmic Solution 0.6% in the Conjunctival Allergen Challenge (Ora-CAC®) Model.

Allergic Conjunctivitis

United States
Alcon Research

Completed

Travatan Z in Ocular Surface Health in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma
Eyenovia Inc.

Recruiting

Microdosed Atropine 0.1% and 0.01% Ophthalmic Solutions for Reduction of Pediatric Myopia Progression

Myopia

United States
Qlaris Bio, Inc.

Completed

A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101

Ocular Hypertension | Glaucoma | Glaucoma Congenital | Sturge-Weber Syndrome (SWS)

United States
Ji Xing Pharmaceuticals (Shanghai) Co., Ltd.
LENZ Therapeutics, Inc

Completed

Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia

Presbyopia

China
Emory University

Completed

A Low ChloridE hyperTonic Solution for Brain Edema (ACETATE)

Acute Kidney Injury | Subarachnoid Hemorrhage

United States
Marinomed Biotech AG

Completed

Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis

Allergic Rhinitis | Allergic Conjunctivitis

Austria
Walter Reed Army Medical Center

Completed

Effect of Brimonidine Tartrate Ophthalmic Solution 0.15% on Pupil Diameter in Normal Eyes

Healthy

United States
Alcon Research

Completed

Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
Alcon Research

Completed

Phase III Clinical Trial of TRAVATAN Z in Ocular Surface Health

Ocular Hypertension | Open-angle Glaucoma
Alcon Research

Completed

Effects of Travatan Z and Xalatan on Ocular Surface Health

Ocular Hypertension | Glaucoma
Ocuphire Pharma, Inc.

Active, not recruiting

Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With Presbyopia (VEGA-2)

Presbyopia

United States
Alcon Research

Completed

A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

United States
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation and Pain

Post Surgical Ocular Inflammation and Pain

United States
Toyos Clinic
Bausch & Lomb Incorporated

Completed

Clinical Outcomes of Bromday (Bromfenac Ophthalmic Solution) 0.09% QD vs. Nevanac (Nepafenac Ophthalmic Suspension) 0.1%

Inflammation | Pseudophakia
Michael D. Straiko, MD
Lions VisionGift Research; Eye Bank Association of America

Recruiting

Ripasudil for Enhanced Corneal Clearing Following Descemet Membrane Endothelial Keratoplasty in Fuchs' Dystrophy

Fuchs Endothelial Dystrophy

United States
Santen Oy

Completed

A Study to Evaluate Pharmacokinetics of Tafluprost Ophthalmic Solution (0.0015%) in Pediatric Patients With Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma

United Kingdom, United States
Jadran Galenski laboratorij d.d.
Poseidon CRO

Completed

Vizol S Lipid Balance Efficacy and Safety Study in Patients With Dry Eye

Dry Eye Disease

Serbia
University of the Incarnate Word

Unknown

Short-term Effect of Rho-kinase Inhibitor on Retinal Circulation

Glaucoma, Open-Angle

United States
Yonsei University

Completed

Clinical Effects of Diquas-S for Patients With Dry Eye After Cataract Surgery

Dry Eye | Cataract Surgery

Korea, Republic of
Santen Pharmaceutical Co., Ltd.

Completed

A Long-term Study of DE-117 Ophthalmic Solution Monotherapy and Concomitant Use of DE-117 Ophthalmic Solution With Timolol Ophthalmic Solution in Patients With OAG or OH: RENGE Study

Open Angle Glaucoma or Ocular Hypertension

Japan
Alcon Research

Completed

Adjunctive Study of AL-37807 Ophthalmic Suspension

Ocular Hypertension | Open-Angle Glaucoma

United States
Alcon Research

Completed

A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma
University of Miami

Completed

Suture Contamination Rate in Adjustable Suture Strabismus Surgery

Suture Strabismus Surgery

United States
Minnesota Eye Consultants, P.A.
Bausch & Lomb Incorporated

Completed

The Effect of BEPREVE 1.5% on Tear Film Osmolarity and Tear Film Lipid Layer

Allergic Conjunctivitis

United States
University of Utah

Completed

Study for the Treatment of Ocular Chronic Graft-Versus-Host Disease (GVHD) With Amniotic Fluid Eye Drops (AFED)

Ocular Graft Versus Host Disease

United States
Shire

Completed

Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1) (OPUS-1)

Keratoconjunctivitis Sicca | Dry Eye Disease

United States
Chengdu Kanghong Biotech Co., Ltd.

Unknown

An Exploratory Clinical Trial Evaluating the Tolerability and Efficacy of KH906 in Patients With Corneal Neovascularization

Corneal Neovascularization

China
Radboud University Medical Center
Oogziekenhuis Rotterdam

Recruiting

Steroid Eye Drops in Chronic Central Serous Chorioretinopathy (PICS)

Chronic Central Serous Chorioretinopathy

Netherlands
Shire

Completed

A Phase 3 Study to Evaluate the Efficacy of Lifitegrast in Subjects With Dry Eye

Dry Eye Disease

United States
Shire

Completed

Efficacy Study to Evaluate the Effectiveness of 3 Concentrations of SAR 1118 in Allergic Conjunctivitis

Allergic Conjunctivitis

United States
Instituto de Oftalmología Fundación Conde de Valenciana

Completed

Effect of Topical Besifloxacin on Ocular Surface Bacterial Microbiota Prior to Cataract Surgery

Cataract Senile | Microbial Disease

Mexico
Shire

Completed

A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE)

Dry Eye

United States
Alcon Research

Completed

Next Generation Ophthalmic Irrigating Solution Posterior Segment Study

Eye Diseases

United States
Ohio State University
Mayo Clinic; National Eye Institute (NEI); University of Nebraska

Recruiting

Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variance

Glaucoma | OHT - Ocular Hypertension

United States
Santen Inc.

Completed

A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 Study

Glaucoma and Ocular Hypertension

United States
Meir Medical Center

Unknown

Effect of Moxifloxacin Versus Gatifloxacin on Corneal Epithelium Following Pterygium Excision

Primary Pterygium

Israel
Ophthalmic Consultants of Boston
Allergan

Unknown

Effectiveness Study of Zymar Versus Vigamox for Preoperative Sterilization of the Ocular Surface After Loading Dose

Infection | Eye Infection

United States
Alcon Research

Completed

Safety and Efficacy of Next Generation Ophthalmic Irrigating Solution Compared to BSS Plus

Cataract

United States
Alcon Research

Completed

Safety of NGOIS Compared to BSS Plus in Pediatric Patients

Cataract

United States
Skye Bioscience, Inc.

Completed

Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States

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