Search clinical trials for: PB1046 Injection

Total 9632 results

PhaseBio Pharmaceuticals Inc.

Completed

Study to Assess the Safety, Tolerability and PK/PD After 4 Weekly SC Injections of PB1046 in Subjects With Stable HFrEF

Heart Failure

United States
PhaseBio Pharmaceuticals Inc.

Terminated

Long-Term, Open Label Extension Study of Pemziviptadil (PB1046) in PAH Subjects Following Completion of Study PB1046-PT-CL-0004 (VIP Extend)

Pulmonary Arterial Hypertension

United States
PhaseBio Pharmaceuticals Inc.

Completed

A Study to Assess the Safety, Tolerability, and Hemodynamic Response of PB1046 in Subjects With PAH

Pulmonary Arterial Hypertension

United States
PhaseBio Pharmaceuticals Inc.

Completed

Pharmacokinetic, Safety/Tolerability Study of a Single SC Dose of PB1023 Injection in Subjects With Normal and Impaired Renal Function

Diabetes Mellitus, Type 2

United States
University of California, Los Angeles

Completed

Transcatheter Valve Implantation in Patients With Dysfunctional Left and Right Sided Heart Valves

Eisenmenger Syndrome

United States
PhaseBio Pharmaceuticals Inc.

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response of Vasomera (PB1046) Injection Following a Single Subcutaneous Dose in Subjects With Stage 1 or 2 Essential Hypertension

Essential Hypertension

United States
PhaseBio Pharmaceuticals Inc.

Terminated

Phase 2 Study to Assess Safety, Tolerability and Efficacy of Once Weekly SC Pemziviptadil (PB1046) in Subjects With Symptomatic PAH (VIP)

Pulmonary Arterial Hypertension

United States
PhaseBio Pharmaceuticals Inc.

Terminated

Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). (VANGARD)

Pneumonia | Respiratory Failure | Respiratory Insufficiency | COVID 19 | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Coronavirus | Cytokine Storm | Pulmonary Edema | Cardiac Event | Respiratory Complication | Cardiac Dysfunction | Hypoxemic Respiratory Failure | Hypoxic Respiratory Failure | Cardiac Failure | Cardiac... and other conditions

United States
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1, Randomized, Double-Blind, Placebo-Controlled Exploratory Study That Will Assess the Safety, Tolerability, Pharmacokinetics and Hemodynamic Response to a Single 30 Minute Intravenous Infusion of Vasomera™ (PB1046) in Adult Subjects With Stage 1 or 2 Essential Hypertension

Essential Hypertension

United States
PhaseBio Pharmaceuticals Inc.

Completed

Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
PhaseBio Pharmaceuticals Inc.

Completed

Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM

Type 2 Diabetes Mellitus

United States
Medtronic Heart Valves

Completed

Melody PB1016 Surveillance Study

Dysfunctional RVOT Conduits in Patients With Congenital Heart Defects

Spain, United States, Austria, Canada
Afyonkarahisar Health Sciences University

Completed

The Efficacy of PRP Injection in the Treatment of Rotator Cuff Syndrome (PRP)

Musculoskeletal Diseases | Shoulder Pain | Rotator Cuff Tendinopathy | Rotator Cuff Syndrome

Turkey
GI Biome, Inc.

Recruiting

Live Biotherapeutic Product GB104 Phase 1 Study in Colorectal Cancer

Cancer | Colorectal Cancer | Rectal Cancer | Solid Tumor | Sigmoid Colon Cancer | Rectosigmoid Junction Cancer

Korea, Republic of
PhaseBio Pharmaceuticals Inc.

Completed

Pharmacokinetic Profile of Two Formulations of PB1023 Following Single Subcutaneous Injection in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Proacta, Incorporated

Unknown

PR104 in Treating Patients With Refractory/Relapsed Acute Leukemia

Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
Brigham and Women's Hospital

Completed

Establishing 18F-PBR06 PET Imaging as a Viable Pharmacodynamic Endpoint in MSA

MSA

United States
Proacta, Incorporated

Completed

A Phase I Dose Escalation Trial of PR104 Given Weekly in Subjects With Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

New Zealand
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
Brigham and Women's Hospital
Genzyme, a Sanofi Company

Not yet recruiting

Effect of Alemtuzumab on Microglial Activation Positron Emission Tomography (PET) in Multiple Sclerosis

Multiple Sclerosis

United States
Institute for Neurodegenerative Disorders

Terminated

Evaluation of [18F] PBR06 and PET as a Marker of Inflammation in Subjects With Neurological Conditions (PBR06)

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease

United States
Molecular NeuroImaging

Completed

Evaluation of Microglial Activation in ALS With [18F]PBR06 (Peripheral Benzodiazepine Receptor-06) PET

Amyotrophic Lateral Sclerosis | Healthy Volunteers

United States
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy

Post-Operative Pain

Korea, Republic of
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Completed

Love Infection: A Dramatized Story Intervention (Telenovela/Soap Opera) for HIV Prevention (IA)

HIV Infections

United States
Brigham and Women's Hospital

Recruiting

Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement Disorders

Synucleinopathies | Neurodegenerative Diseases | Ataxia | sca3 | MSA - Multiple System Atrophy

United States
University Hospital, Bordeaux

Terminated

Molecular Imaging of Inflammation With 18F-PBR06 to Identify Unstable Carotid Plaques in Patients With Stroke (PLAQINSTEP)

Stroke

France
GlaxoSmithKline

Completed

In-patient Study With GSK716155 In Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Rehabilitace MUDr. Hasan Mezian s.r.o.

Unknown

Effectiveness of Ultrasound Guided Corticoanesthetic Injection in Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

Czechia
Brigham and Women's Hospital
Biohaven Pharmaceuticals, Inc.

Completed

Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients

Multiple System Atrophy | Multiple System Atrophy, Parkinson Variant (Disorder) | Multiple System Atrophy, Cerebellar Variant | Multiple System Atrophy (MSA) With Orthostatic Hypotension

United States
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Second Affiliated Hospital of Soochow University

Recruiting

UTAA17 Injection in the Treatment of Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

China
University of Leipzig
Celgene Corporation

Recruiting

Efficacy of Luspatercept in ESA-naive LR-MDS Patients With or Without Ring Sideroblasts Who do Not Require Transfusions (LENNON)

Myelodysplastic Syndromes | Anemia

Germany
Vivozon, Inc.

Completed

Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Postoperative Pain Following Total Hip Arthroplasty.

Post-Operative Pain

Korea, Republic of
Indiana University

Completed

Prospective Study of Celiac Block Injection: 1 vs. 2

Pancreatic Cancer | Chronic Pancreatitis

United States
Brigham and Women's Hospital
U.S. Army Medical Research Acquisition Activity

Recruiting

Role of Microglial Activation and Norepinephrine Transporter Abnormalities in Pathogenesis of MS-related Fatigue

Multiple Sclerosis

United States
Labrha
Statitec

Completed

Safety of Use of Pandora for Patients Suffering From Gonarthrosis (PANDORA1)

Knee Osteoarthritis

France
Istituto Ortopedico Rizzoli

Recruiting

Homologous PRP vs Placebo in Knee Osteoarthritis in Over 65 Years Old Patients

Knee Osteoarthritis

Italy
Brigham and Women's Hospital
Novartis

Recruiting

9-month Study to Assess the Efficacy of Ofatumumab on Microglia in Patients With Relapsing Forms of Multiple Sclerosis

Relapsing Multiple Sclerosis

United States
Brigham and Women's Hospital

Unknown

Microglial Activation Positron Emission Tomography (PET) Brain Imaging in Multiple Sclerosis and Alzheimer's Disease (MAPET)

Multiple Sclerosis | Alzheimer's Disease

United States
Panolos Bioscience

Recruiting

Phase I Study to Evaluate Safety and Anti-tumor Activity of PB101, an Anti-angiogenic Immunomodulating Agent

Metastatic Colorectal Cancer | Hepatocellular Carcinoma | Gastric Cancer | Solid Tumor | Advanced Solid Tumor | Solid Tumor, Adult

Korea, Republic of
Proacta, Incorporated

Terminated

PR104 in Treating Patients With Previously Untreated or Relapsed Small Cell Lung Cancer

Lung Cancer

United States
Western Galilee Hospital-Nahariya

Recruiting

Comparing Methods for Balloon Catheter Inserting: View Guided (Speculum) Versus Manual Guided at Cervical Examination

Cervical Ripening

Israel
Indiana University School of Medicine

Completed

Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?

Colorectal Cancer | Colorectal Polyps

United States
Rothman Institute Orthopaedics

Unknown

Study Comparing One Versus Two Cortisone Injections for Trigger Finger

Trigger Finger | Stenosing Tenosynovitis

United States
Yangzhou University

Not yet recruiting

Application of Different Modes of Esketamine Administration in Pediatric Day Circumcision

Pain
Makassed General Hospital

Recruiting

Effectiveness of Single Paravertebral Blockade Injection for Herniorrhaphy in Children

Reduce Pain After Herniorrhaphy

Lebanon
Theravectys S.A.

Not yet recruiting

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Geisinger Clinic

Terminated

Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy (RAISE-KT)

Obesity | Diabetic Kidney Disease | Type 2 Diabetes Mellitus in Obese | CKD | Severe Obesity

United States
Peking University Third Hospital

Recruiting

Clinical Study to Evaluate the Efficacy and Safety of FB1006 in the Treatment of ALS Patients (FB1006)

Sporadic and Familial Amyotrophic Lateral Sclerosis

China
Roxall Medizin

Completed

Efficacy and Safety of Specific Immunotherapy With CLUSTOID Grass Pollen

Allergic Rhinitis

Germany
Sindolor

Suspended

Safety and Efficacy of EZ-Ject Injector a Pain-Free Subcutaneous Automatic Injection in Healthy Volunteers

Healthy

Israel

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