Search clinical trials for: PBF-999

Total 2825 results

Palobiofarma SL
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Terminated

Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-999 "After Multiple Oral Doses" in Healthy Volunteers

Huntington Disease

Spain
Palobiofarma SL
Vall d'Hebron institute of oncology (VHIO), Catalan institute of oncology...

Completed

Study of PBF-999 in Solid Tumour Advanced Cancer

Cancer

Spain
Fundació Institut de Recerca de l'Hospital de la...
Palo Biofarma, S.L

Completed

Study To Assess the Safety and Tolerability of Single Ascending Oral Doses of PBF-999 in Healthy Young Male Volunteers

Huntington's Disease

Spain
Aerovance, Inc.

Completed

A Phase 2a Study to Investigate the Effects of Repeated Administration of AeroDerm in Subjects With Atopic Eczema

Atopic Eczema

United Kingdom
Beijing Shenogen Biomedical Co., Ltd
The First Affiliated Hospital with Nanjing Medical University; Guilin Medical... and other collaborators

Unknown

The Phase III Study of Icaritin Versus HUACHANSU PIAN in Hepatocellular Carcinoma Subjects

Advanced HBV-Related Hepatocellular Carcinoma (HCC)

China
OBI Pharma, Inc

Terminated

Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors

Locally Advanced Solid Tumor

United States
Takeda

Recruiting

A Study About Fazirsiran in People With and Without Liver Problems

Hepatic Impairment

Hungary, Slovakia
T3D Therapeutics, Inc.
National Institute on Aging (NIA); Alzheimer's Association; Clinilabs, Inc.

Completed

Clinical Study Evaluating Efficacy and Safety of T3D-959 in Mild-to-moderate AD Subjects

Alzheimer Disease

United States
Palobiofarma SL
Novartis; H. Lee Moffitt Cancer Center and Research Institute

Completed

Trial of PBF-509 and PDR001 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) (AdenONCO)

Non-small Cell Lung Cancer (NSCLC)

United States
University Hospital, Tours

Terminated

Quantification of Dopamine Active Transporter (DAT) in Humans: Validation of a New Radiophamaceutical, the [18F] LBT-999 (LBT 999)

Idiopathic Parkinson Disease

France
Institute of Tropical Medicine, Belgium
World Bank; Ministry of Health, Burundi; Institut de Statistiques, Burundi (ISTEEBU) and other collaborators

Completed

Measuring and Understanding the Effects of a Performance Based Financing Scheme Applied to Nutrition Services in Burundi (NutriPBF)

Malnutrition
Takeda

Enrolling by invitation

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease

Alpha1-Antitrypsin Deficiency

United Kingdom, Germany, United States, Austria, Portugal
Takeda

Recruiting

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Alpha1-Antitrypsin Deficiency

United States
Takeda

Completed

Study to Evaluate Absorption, Metabolism, and Excretion, of TAK-994 in 6 Healthy Male Adults

Healthy Volunteers

United States
Arrowhead Pharmaceuticals

Active, not recruiting

Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD)

Alpha 1-Antitrypsin Deficiency

Austria, Germany, United Kingdom
Takeda
Takeda Development Center Americas, Inc.

Recruiting

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

Alpha1-Antitrypsin Deficiency

United States, Belgium, Switzerland, Canada, Australia, Germany, United Kingdom, Austria, France, Spain, Portugal, Italy, Poland
Takeda

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of TAK-994 in Healthy Participants

Healthy Participants

United States
AbbVie

Terminated

Study to Assess Adverse Events and How Oral ABBV-990 Moves Through the Body of Adult Healthy Participants

Healthy Volunteers

United States
Oregon Health and Science University
Ionis Pharmaceuticals, Inc.

Recruiting

carDIo-ttranSSfOrm nucLEar Imaging Study (DISSOLvE)

Amyloidosis | Transthyretin Amyloid Cardiomyopathy

United States
Fundació Institut de Recerca de l'Hospital de la...
Palo Biofarma, S.L

Completed

Study to Assess the Efficacy of a Single PBF-680 Oral Administration to Attenuate Adenosine 5'-Monophosphate Challenge-induced Airway Hyperresponsiveness in Mild-to-moderate Asthmatics

Asthma

Spain
Mathew S. Maurer
National Heart, Lung, and Blood Institute (NHLBI); Yale University; Boston Medical... and other collaborators

Recruiting

Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations (SCAN-MP)

Amyloid Cardiomyopathy, Transthyretin-Related

United States
BTL Industries Ltd.

Completed

Effect of the BTL-899 Therapy for Non-invasive Lipolysis and Circumference Reduction of Abdomen

Improvement of Abdomen Appearance

Bulgaria
BTL Industries Ltd.

Completed

Effect of BTL-899 Device for Non-invasive Lipolysis on Human Upper Arms

Fat Burn

Bulgaria
AbbVie

Completed

A Study to Evaluate the Safety and Pharmacokinetics ABBV-399 in Japanese Participants With Solid Tumors

Advanced Solid Tumors Cancer

Japan
Alkermes, Inc.
QPS Netherlands B.V.

Completed

Single and Multiple Ascending Dose and Food Effect PK Study in Healthy Adult and Elderly Subjects

Healthy

Netherlands
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics, of VX-993

Pain

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1 Dose Escalation Study of VX-993 in Healthy Participants

Pain

United Kingdom
Takeda

Terminated

A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy

Narcolepsy Type 1 (NT1) | Narcolepsy Type 2 (NT2)

China, United States, Korea, Republic of, France, Italy, Finland, Spain, Czechia, Canada, Japan, Hungary, Netherlands
BTL Industries Ltd.

Completed

High-Intensity Focused Electromagnetic Procedure and Radiofrequency for Toning of Buttocks

Muscle Tone

United States
Arrowhead Pharmaceuticals

Completed

Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT) (SEQUOIA)

Alpha 1-Antitrypsin Deficiency

United States, Spain, Netherlands, Germany, Italy, Portugal
Memorial Health University Medical Center

Unknown

Tilmanocept vs Sulfur Colloid in Sentinel Lymph Node Biopsy

Breast Cancer | Sentinel Lymph Node Biopsy

United States
AbbVie

Recruiting

A Study to Assess Adverse Events, and How Intravenously (IV) Infused ABBV-969 Moves Through the Bodies of Adult Participants With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer

United States
BTL Industries Ltd.

Active, not recruiting

Non-invasive Lipolysis and Improvement of Muscle Tone in Lateral Abdomen

Fat Burn

United States
BTL Industries Ltd.

Completed

Histological Evaluation of BTL-899 Device´s Effect on Fat Tissue

Fat Burn

United States
BTL Industries Ltd.

Completed

rPMS and Radiofrequency for Abdominal Toning and Reduction of Subcutaneous Fat

Fat Burn

United States
BTL Industries Ltd.

Completed

Non-invasive Lipolysis on Human Thighs and Saddlebags

Adipose Tissue Reduction

Bulgaria
T3D Therapeutics, Inc.

Completed

Feasibility Study in Subjects With Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
D-Pharm Ltd.

Completed

Effects Of DP-b99 On Neurological Function In Subjects With Acute Ischemic Hemispheric Stroke

Stroke | Cerebrovascular Disorders | Brain Ischemia

Israel, Germany
AbbVie

Active, not recruiting

A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

United States, Australia, France, Germany, Israel, Italy, Japan, Korea, Republic of, Taiwan
Washington University School of Medicine
Lloyd J. Old STAR Program

Terminated

Mapping Draining Lymph Nodes in CNS Malignancies

Central Nervous System Neoplasms | Central Nervous System Tumor

United States
Navidea Biopharmaceuticals

Completed

Evaluation of the Precision and Sensitivity of Tilmanocept Uptake Value (TUV) on Tc 99m Tilmanocept Planar Imaging

Rheumatoid Arthritis

United States
Flare Therapeutics Inc.

Recruiting

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

Advanced Solid Tumors Cancer | Advanced Urothelial Carcinoma | Open Label | Oral Drug Administration

United States
Amgen

Terminated

Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers

MUC17-positive Solid Tumors

United States, Korea, Republic of, Taiwan, Spain, Austria, France, Japan, Germany, Netherlands
BTL Industries Ltd.

Completed

Non-invasive Lipolysis and Improvement of Muscle Tone in Upper Arms

Fat Disorder

United States
BTL Industries Ltd.

Completed

Fat Reduction and Muscle Toning of Thighs

Fat Burn

United States
BTL Industries Ltd.

Completed

Non-invasive Lipolysis and Improvement of Muscle Tone in Inner Thighs

Fat Disorder

United States
Takeda

Completed

A Study of Different Forms of TAK-994 in Healthy Adults

Healthy Participants

United States
BTL Industries Ltd.

Completed

Clinical Evaluation of the BTL-899 Device for Non-invasive Lipolysis on Human Fat Tissue

Improvement of Abdomen Appearance

Bulgaria
Pfizer

Completed

Monthly And Twice Monthly Subcutaneous Dosing Of PF-04950615 (RN316) In Hypercholesterolemic Subjects On A Statin

Hypercholesterolemia

United States
Central Hospital, Nancy, France

Completed

Comparison Between Myocardial Tomoscintigraphies Using a Semiconductor Camera or a Conventional Camera (DSPECT)

Myocardial Infarction | Ischemia

France

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