Search clinical trials for: PPI-668

Total 2344 results

Presidio Pharmaceuticals, Inc.

Completed

Phase 1 Study of Relative Bioavailability of PPI-668 New Tablet Versus Capsule Formulations

Pharmacokinetic Assessments in Healthy Volunteers

United States
Presidio Pharmaceuticals, Inc.

Completed

Phase 1 Study of Relative Bioavailability of PPI-668 Tablet and Capsule Formulations

Pharmacokinetic Assessments in Healthy Volunteers

United States
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1 Study of PPI-668 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) Genotype 1

Hepatitis C, Chronic

United States, Australia, New Zealand
Drugs for Neglected Diseases
Ministry of Health, Malaysia; Ministry of Health, Thailand; National Science...

Active, not recruiting

Strategic Transformation of the Market of HCV Treatments (STORM-C-1)

Hepatitis C

Malaysia, Thailand
University of California, San Francisco
Filament Health

Recruiting

Comparing the Effects of Psilocin and Psilocybin in Healthy Adults

Healthy

United States
Muhammad Radzi Abu Hassan

Recruiting

8- Versus 12-week of Sofosbuvir-ravidasvir Treatment of Chronic Hepatitis C

Hepatitis C

Malaysia
Cornerstone Pharmaceuticals

Withdrawn

Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States
Pharco Pharmaceuticals

Unknown

A Study of the Efficacy and Safety of PPI-668 (NS5A Inhibitor) Plus Sofosbuvir, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype-4

Chronic Hepatitis C

Egypt
AbbVie

Recruiting

Study of ABBV-668 Oral Capsules to Assess Adverse Events and Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Belgium, France, Poland
Cornerstone Pharmaceuticals

Terminated

Phase 2 Safety, Tolerability and Efficacy Study of CPI-613 in Cancer Patients

Cancer

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 1, First-in-human Study of VX-668

Alpha-1 Antitrypsin Deficiency

United States
Presidio Pharmaceuticals, Inc.
Boehringer Ingelheim

Completed

Study of PPI-668, BI 207127 and Faldaprevir, With and Without Ribavirin, in the Treatment of Chronic Hepatitis C

Chronic Hepatitis C

United States
Rigshospitalet, Denmark

Active, not recruiting

DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial Infarction (DANAMI-3)

ST Segment Elevation Myocardial Infarction

Denmark
Shire

Completed

Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Czechia, Germany, Latvia, Poland, Romania
University of Southern California

Withdrawn

PPI Versus Placebo in Severe Functional Heartburn

GERD

United States
Al-Azhar University

Not yet recruiting

Minimally Invasive Scrotal Incision for Penile Prosthesis Implantation, Novel Technique. (PPI)

Penile Prosthesis Infection | Penile Prosthesis; Complications, Infection or Inflammation
PRAECIS Pharmaceuticals Inc.

Terminated

Safety/Tolerance Study of PPI-2458 in Subjects With Non-Hodgkin's Lymphoma and Solid Tumors

Solid Tumors | Non-Hodgkin's Lymphoma,

United States
University College, London
National Institute for Cardiovascular Outcomes Research; British Cardiovascular... and other collaborators

Completed

Exploring the Volume-Outcome Relationship for PCI Procedures Undertaken in a UK Context: A NICOR Study

Percutaneous Coronary Intervention

United Kingdom
Yonsei University

Completed

Efficacy of Proton Pump Inhibitor for Chronic Cough Caused by Gastroesophageal Reflux; Double-blind, Placebo-controlled, Randomized Clinical Trial

Chronic Cough Caused by Gastroesophageal Reflux

Korea, Republic of
Braintree Laboratories

Recruiting

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

Erosive Esophagitis

United States
PRAECIS Pharmaceuticals Inc.

Completed

Safety Study of PPI-1019 in Subjects With Mild-Moderate Alzheimer's Disease

Alzheimer's Disease

United States
PRAECIS Pharmaceuticals Inc.

Completed

Safety Study of PPI-1019 in Patients With Mild-Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Soonchunhyang University Hospital

Completed

Surgicel® Fibrillar for Delayed Bleeding After ESD

Malignant Neoplasm of Stomach | Benign Neoplasm of Stomach

Korea, Republic of
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease (PPi-DIA)

Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control

France
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of the "Pupillary Pain Index" in Neurological Prognosis After Cardiac Arrest (CAPPI)

Cardiac Arrest | Anoxic Brain Injury | Post-Anoxic Coma
Zhongshan Ophthalmic Center, Sun Yat-sen University

Completed

Prophylactic Peripheral Iridectomy Prevents Aphakic Angle-closure Glaucoma

Congenital Cataract | Aphakic Glaucoma

China
University Hospital, Caen

Completed

Delirium Related to Proton Pump Inhibitors Use

Delirium | Hyponatremia | Proton Pump Inhibitor Adverse Reaction

France
HaEmek Medical Center, Israel

Completed

Prepulse Inhibition (PPI) of Startle Reflex in Schizophrenia Patients Related to Type of Treatment and Illness Duration

Schizophrenia | Medication Adherence | Inhibition (Psychology)

Israel
Centre Hospitalier Universitaire de Nice

Recruiting

PPI Supplementation to Fight ECtopIc Calcification in PXE (PROPHECI-PPI)

Pseudoxanthoma Elasticum

France
Minia University

Completed

Preoperative PPI in Sleeve Gastrectomy

Morbid Obesity

Egypt
National Hepatology & Tropical Medicine Research...

Recruiting

Role of Octreotide in Non Variceal Bleeding

Non-variceal Gastrointestinal Bleeding

Egypt
Centre Hospitalier Universitaire Dijon

Completed

the Impact of Paediatric Use of Proton Pump Inhibitors on the Risk of Community Acquired Infections. (UTOPIE)

Community Infections

France
Rabin Medical Center

Withdrawn

Gastric Acid Rebound Secretion Measured by Alkaline Tide

Condition Measuring Alkaline Tide and Filling Symptoms' Questionnaire After Abrupt or Gradual Step Down Cessation of PPI
Samsung Medical Center

Recruiting

Emulation of Randomized Clinical Trial in Cardiovascular Disease (RCT-BigData)

Myocardial Infarction | Coronary Artery Disease

Korea, Republic of
Yonsei University

Completed

Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease

Non-erosive Gatroesophageal Reflux Disease

Korea, Republic of
Universitaire Ziekenhuizen KU Leuven

Recruiting

Primary carE PPi dEprescRibing Trial (PEPPER)

Dyspepsia | Heartburn | Reflux

Belgium
Takeda

Completed

Dose Finding Study of Vedolizumab for GvHD in Participants Undergoing Allogeneic HSCT

Allogeneic Hematopoietic Stem Cell Transplantation

United States
Duke University

Recruiting

Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic Encephalopathy

Hepatic Encephalopathy

United States
University of California, Davis

Completed

Casinomacropeptide and Satiety (CMP2)

Appetite Disorders | Lack of Satiety | Excess Intake of Macronutrients

United States
Prolacta Bioscience

Completed

Dietary Supplement With and Without a Probiotic

Healthy Adult Subjects

United States
EndoGastric Solutions

Completed

The EndoGastric Solutions TEMPO Trial (TEMPO)

Gastroesophageal Reflux Disease (GERD)

United States
Nantes University Hospital

Completed

Efficacy of a Multi-faceted Intervention to Deprescribe Proton Pump Inhibitors (PPI) in Primary Care: a Population-based, Pragmatic, Cluster-randomized Controlled Trial. (DeprescrIPP)

Proton Pump Inhibitors | Deprescription

France
University of Colorado, Denver
Cystic Fibrosis Foundation

Terminated

Effect of Acid Blockade on Microbiota and Inflammation in Cystic Fibrosis (CF)

Cystic Fibrosis

United States
BeyondSpring Pharmaceuticals Inc.
Covance; ICON plc

Completed

Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 3 (Protective-1)

Chemotherapy-induced Neutropenia

China, Russian Federation, United States, Ukraine
Carmot Therapeutics, Inc.

Recruiting

A Study of CT-868 in Type 1 Diabetes Mellitus

Overweight | Type 1 Diabetes Mellitus | Obese

United States
Mitsubishi Tanabe Pharma America Inc.

Completed

Relative Bioavailability and Drug-drug Interaction Study With MT-7117 and a Proton Pump Inhibitor (MT-7117 BA DDI)

Healthy Volunteer

Germany
VA Office of Research and Development
VHA Pharmacy Benefits Management Services VA Center For Medication Safety

Completed

Evaluation of the National Randomized Proton Pump Inhibitor De-prescribing (RaPPID) Program (RaPPID)

Proton Pump Inhibitors

United States
Guy's and St Thomas' NHS Foundation Trust
Takeda

Unknown

Investigation of the Faecal Loss of Vedolizumab and Its Role in Influencing Serum Drug Levels, Outcomes and Response in Ulcerative Colitis (FAVOUR)

Ulcerative Colitis

United Kingdom
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1b Study of PPI-461 in Patients With HCV Genotype 1

Chronic Genotype 1 Hepatitis C Virus Infection

United Kingdom, Denmark, United States
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1a/1b Study of PPI-383 in Healthy Adults and Hepatitis C Patients

Hepatitis C, Chronic

United Kingdom, Mauritius

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