Search clinical trials for: Physiological Effects of Drugs

Total 146494 results

Baskent University

Completed

Ambulatory Blood Pressure Reduction After Rosiglitazone Treatment In Normotensive Type 2 Diabetic Patients

Diabetes Mellitus, Type 2

Turkey
Santhera Pharmaceuticals

Withdrawn

Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)

Leber's Hereditary Optic Neuropathy
University Hospital, Caen

Unknown

Observational Study of the Analgesic Effect of Treatment With rTMS in Patients With Chronic Neuropathic Pain (rTMSDOULNEURO)

Chronic Pain

France
Assiut University

Not yet recruiting

Predictive Value of Venous Excess Ultrasound Score in Management of Cardiorenal Patients

Cardio-Renal Syndrome
Diakonhjemmet Hospital
Vestre Viken Hospital Trust; Hormone Laboratory, Aker University Hospital,...

Not yet recruiting

Dynamics in Bone Turnover Markers During and After Short-term Glucocorticoid Treatment in Patients With an Inflammatory Joint Disease (BOOGIE)

Osteoporosis | Inflammatory Rheumatism | Osteoporosis, Steroid Induced
Marinus Pharmaceuticals

Completed

Adjunctive Ganaxolone Treatment (Part A) in TSC Followed by Long-term Treatment (Part B) (TSC)

Tuberous Sclerosis

United States
University Hospital Tuebingen

Recruiting

Transport of Satiety Factors Into the CSF

Obesity

Germany
Universidad del Desarrollo

Completed

the Effect Site Equilibration Time of Propofol is Age Dependant (ke0agedep)

Healthy

Chile
Baskent University

Completed

Effects of Rosiglitazone on Plasma BNP Levels and Left Ventricular Dysfunction

Diabetes Mellitus, Type 2

Turkey
Technische Universität Dresden

Completed

Investigation of Vascular Relaxing Effects of the Antidiabetic Rosiglitazone.

Healthy Subjects

Germany
University of Siena
IBSA Institut Biochimique SA

Unknown

Effect of Semet (80 and 160 mcg) Versus Placebo in Euthyroid Patients With AIT

Thyroiditis Autoimmune
Kerman Medical University
Afzalipour Hospital

Not yet recruiting

Efficacy of NOSHINtrial in Diabetic Patients (NOSHIN)

Diabetes Mellitus, Type 2 | Insulin Resistance

Iran, Islamic Republic of
Robin Carhart-Harris, PhD, MA

Recruiting

Neural and Physiological Correlates of Psychedelic Sub-states (i2)

Healthy Volunteers | Psychedelic Experiences | Neuroimaging

United States
Assiut University

Not yet recruiting

Prevalence of IR in Overweight and Obese Adolescents (IR)

Insulin Resistance
Bursa Yüksek İhtisas Education and Research Hospital

Completed

Anesthesia on Optic Nerve Sheath Diameter

Optic Nerve Sheath Diameter

Turkey
University Hospital Ostrava

Completed

Development of Antibodies Against Transplant Kidney After Infection

Kidney Failure | Acute Infection

Czechia
Ming Lv

Recruiting

Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE) (METTLE)

Dissecting Aneurysm of Cerebral Artery

China
University of Illinois at Chicago
Emily Hanners; Dulal Bhaumik; Avisek Datta; Peggy Choye; Hailey Soni; Annesti Elmasri; Julie Jun and other collaborators

Not yet recruiting

Effect of Continuing Versus Holding Metformin During Hospitalizations.

Diabetes Mellitus, Type 2

United States
Military Institute of Medicine, Poland
ABM Industries

Recruiting

"MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome

Acute Coronary Syndrome

Poland
University Hospital Inselspital, Berne
Lindenhofstiftung

Not yet recruiting

Steroid and Behaviour Changes Under Metformin

Autistic Disorder

Switzerland
Institut d'Investigació Biomèdica de Girona Dr....

Recruiting

Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly (SmartAge)

Type 2 Diabetes Mellitus

Spain
Rabin Medical Center

Recruiting

Intensive Versus Conventional Hyperglycemic Control in Hospitalized Non-critically Ill Patients

Diabetes Mellitus | Non-critically Ill Patients

Israel
Medical University of South Carolina

Terminated

Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

Prostate Cancer

United States
Hoffmann-La Roche

Active, not recruiting

This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS)

Multiple Sclerosis

Canada, United Kingdom, Belgium, Brazil, Croatia, Mexico, Slovakia, Ireland, Netherlands, Estonia, Norway, Denmark, Italy, Poland, Spain, Bulgaria, France, Turkey, Portugal, Sweden, Argentina, Kuwait, Slovenia, Czechia, Hungary, Finland
Hoffmann-La Roche

Active, not recruiting

A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

Multiple Sclerosis

United States, Italy, Poland
Biogen

Completed

A Study for Tysabri Participant Preference

Relapsing-Remitting Multiple Sclerosis (RRMS)

Germany
Oxford University Clinical Research Unit, Vietnam
Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Completed

Metformin in Dengue With Obesity (MeDO)

Obesity | Overweight | Dengue | Viral Infection | Metformin | Anti-inflammatory Agents

Vietnam
University of Cagliari

Completed

Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.

Polycystic Ovary Syndrome
Dr Recai Turkoglu
Health Sciences University Istanbul Haydarpaşa Numune Training and Research...

Active, not recruiting

Investigation of the Effect of Ocrelizumab on Peripheral Lymphocyte Immunophenotypes With Suppressive Capacity in MS

Multiple Sclerosis

Turkey
University of Missouri-Columbia

Completed

Impact of Insulin on Sympathetic Nervous System-mediated Peripheral Vasoconstriction

Healthy | Insulin Resistance | Vasoconstriction

United States
Ohio State University

Terminated

Spinal Cord Injury Neuroprotection With Glyburide (SCING)

Acute Spinal Cord Injury

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome

Li-Fraumeni Syndrome

United States
University of California, Los Angeles

Completed

Management of Diabetes With Metformin In Patients With Chronic Heart Failure

Heart Failure | Diabetes

United States
Mario Negri Institute for Pharmacological Research

Terminated

Insulin Treatment in Diabetic Older People With Heart Failure. (Insulin-HF)

Heart Failure | Diabetes Mellitus, Type 2

Italy
Ain Shams Maternity Hospital

Unknown

Endometrial Thickness and Subendometrial Vascularity in Anovulatory Polycystic Ovarian Syndrome Patients Treated by Metformin

Polycystic Ovary Syndrome | Anovulatory

Egypt
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Early Insulin and Development of ARDS

Hyperglycemia | Sepsis | Respiratory Distress Syndrome, Adult

United States
University of Arkansas

Completed

A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women

Adenocarcinoma of the Endometrium

United States
Boston University

Completed

Effects of Lipemia and Metformin on Endothelial Function

Cardiovascular Disease

United States
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Nateglinide in Patients With Type 2 Diabetes Already Taking Insulin Glargine, Metformin and/or Pioglitazone or Rosiglitazone

Type 2 Diabetes

United States
Catholic University of the Sacred Heart

Unknown

Extended-release vs Immediate-release Metformin in PCOS Women

Polycystic Ovary Syndrome

Italy
Seoul National University Hospital

Completed

Pharmacokinetic-Pharmacodynamic Relationship of Metformin in Healthy Volunteers

Healthy
Oluf Borbye Pedersen

Completed

The Effect of Metformin on Composition of Human Gut Bacteria

Healthy

Denmark
National Cancer Institute (NCI)

Terminated

Pioglitazone to Treat Adults Undergoing Surgery for Non-small Cell Lung Cancer

Non-Small-Cell Lung Cancer

United States
University of Southern Denmark

Completed

Study of Metformin Pharmacogenetics in Twins

Type 2 Diabetes

Denmark
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy and Safety of Continuous Intravenous Versus Usual Subcutaneous Insulin in Acute Ischemic Stroke (INSULINFARCT)

Acute Stroke | Acute Cerebral Ischemia

France
US Department of Veterans Affairs
American Diabetes Association

Completed

Markers and Mechanisms of Vascular Disease in Type II Diabetes

Type 2 Diabetes Mellitus

United States, Puerto Rico
Western Sydney Local Health District

Completed

Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndrome (MVENT)

Metabolic Syndrome | Hypercholesterolemia

Australia
University Magna Graecia

Withdrawn

Metformin Administration in Infertile Anovulatory PCOS Patients

Polycystic Ovary Syndrome

Italy
University of Colorado, Denver

Completed

Effect of Rosiglitazone in Nondiabetic Patients With the Metabolic Syndrome

Metabolic Syndrome | Insulin Resistance

United States
Eunice Kennedy Shriver National Institute of Child...

Withdrawn

Effect of Rosiglitazone on Peritoneal Cytokines in Women With Endometriosis

Endometriosis

United States

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