Search clinical trials for: Pilocarpine

Total 63 results

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Wills Eye

Completed

Dose, Effects and Characteristics of Pilocarpine

Open-angle Glaucoma

United States
University of Sao Paulo

Unknown

Effect of Pilocarpine in Patients With Xerostomia

Xerostomia

Brazil
Emory University
Georgia Institute of Technology

Completed

Pilocarpine Microneedles for Sweat Induction (PMN-SI)

Cystic Fibrosis

United States
Glaukos Corporation

Completed

Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease

Dry Eye Disease | Kerato Conjunctivitis Sicca

United States
Glaukos Corporation

Completed

Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia

Presbyopia

United States
AbbVie

Completed

A Study to Assess the Impact and Adverse Events of Topical Eyedrops of AGN-190584 on Night-driving Performance in Participants, 40 to 55 Years of Age (TAURUS)

Presbyopia

Australia
Samsung Medical Center

Unknown

The Effect of Cataract Extraction on the Contractility of Ciliary Muscle

Cataract | Presbyopia

Korea, Republic of
Pontificia Universidad Catolica de Chile
Formulario MAgistral Farmacias Ahumada

Completed

A Comparison of Orally Pilocarpine and Artificial Saliva in Xerostomy Treatment

Xerostomia | Primary Sjogren | Secondary Sjogren

Chile
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Xerostomia

United States, Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Pilocarpine in Treating Vaginal Dryness in Patients With Breast Cancer

Breast Cancer | Vaginal Dryness

United States
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia

Presbyopia
Alcon Research

Completed

Travoprost 0.004% Versus Pilocarpine 1% in Patients With Chronic Angle Closure Glaucoma (CACG)

Angle-closure Glaucoma

United States
Medical University of Vienna

Completed

Measurement of Sweat Sodium Concentration in Patients With Chronic Kidney Disease

Chronic Kidney Diseases

Austria
Isfahan University of Medical Sciences

Active, not recruiting

Efficacy of Pilocarpine 1% in Presbyopia

Presbyopia | Pseudophakia

Iran, Islamic Republic of
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Pilocarpine in Preventing Mucositis and Dry Mouth in Patients Receiving Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Oral Complications

United States, Canada
Federal University of São Paulo

Completed

Oral Pilocarpine in the Treatment of the Dry Eye of Patients With Sjogrens Syndrome

Dry Eye

Brazil
University of Colorado, Denver

Completed

The Diurnal and Nocturnal Effect of Pilocarpine on Intraocular Pressure and Ocular Perfusion Pressure

Hypertension, Ocular | Glaucoma, Open-angle

United States
Orasis Pharmaceuticals Ltd.

Completed

An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2) (NEAR-2)

Presbyopia

United States
Orasis Pharmaceuticals Ltd.

Completed

An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-1) (NEAR-1)

Presbyopia

United States
Eyenovia Inc.

Completed

Safety & Efficacy of Pilocarpine Eye Solutions for Temporary Improvement of Near Vision in Presbyopic Adults (VISION-1)

Presbyopia

United States
NCIC Clinical Trials Group

Terminated

Pilocarpine in Treating Patients With Dry Mouth Caused by Opioids

Quality of Life | Oral Complications

Canada
Maastricht University Medical Center

Completed

Local Pilocarpine for Relieving Dry Mouth

Patients of Advanced Age (≥ 70 Years) With a Clinical Diagnosis of Chronic Dry Mouth

Netherlands
Yune Zhao

Not yet recruiting

Morphological Changes of Ciliary Body and Trabecular Meshwork

Glaucoma | Myopia
Ocuphire Pharma, Inc.

Active, not recruiting

Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With Presbyopia (VEGA-2)

Presbyopia

United States
Novus Vision LLC

Active, not recruiting

Evaluation of NV701 (Pilocarpine 1.25%) Compared with Vuity (Pilocarpine 1.25%) on Pupil Size in Subjects with Presbyopia

Pupil Constriction

United States
Catharina Ziekenhuis Eindhoven

Completed

Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)

Delirium | Cognitive Impairment | Cognitive Dysfunction | Postoperative Delirium | Delirium in Old Age | Cognitive Dysfunction, Postoperative

Netherlands
Shahid Beheshti University of Medical Sciences

Recruiting

Pharmacological Treatment of Presbyopia

Near Vision

Iran, Islamic Republic of
Allergan

Completed

A Phase 3 Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia (GEMINI 2)

Presbyopia

United States
Allergan

Completed

Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia (GEMINI 1)

Presbyopia

United States
Cairo University
Norhan Abdel Aleem Ali; Hagar Hassanein Refaee; Ahmed Abdullah Fathi Mohamed...

Completed

A Comparative Study on Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl for Optimal Dose to be Used in Elderly Patients Undergoing Day Case Lower Abdominal and Urologic Surgeries.

Three Different Doses of Intrathecal Hyperbaric Prilocaine With Fentanyl

Egypt
Allergan

Completed

A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily (Virgo)

Presbyopia

United States
Eyenovia Inc.

Completed

Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults (VISION-2)

Presbyopia

United States
Cliniques universitaires Saint-Luc- Université...

Recruiting

Implementation of a Non-invasive Version of the Imaging β-adrenergic-dependent Sweat Secretion Test (BUBBLE TEST)

Mucoviscidosis Involving the Lung

Belgium
Centre Hospitalier Universitaire Vaudois
University Hospital, Geneva

Completed

Gender Differences in Renal Functioning and Disease (GenderBOLD)

Chronic Renal Failure | Healthy Controls

Switzerland
Richard Barry Moss

Completed

(Study: Vertex IIS) Does Ivacaftor Alter Wild Type CFTR-Open Probability In The Sweat Gland Secretory Coil?

Cystic Fibrosis

United States
Massachusetts Eye and Ear Infirmary

Unknown

Pilocarpine and Brimonidine in Patients With Monofocal Lenses

Presbyopia | Pseudophakia

United States
The New York Eye & Ear Infirmary
Pfizer

Unknown

The International Collaborative Exfoliation Syndrome Treatment Study

Ocular Hypertension | Glaucoma | Exfoliation Syndrome

United States
Prisma Health-Upstate

Completed

Wearing-Off Period of Pharmacological Dilation and Anisocoria

Anisocoria

United States
Optall Vision

Recruiting

Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients (PBOHB)

Presbyopia

Mexico
Medical University of Vienna

Recruiting

Anterior Segment Imaging With Ultrahigh-resolution OCT in Patients With Glaucoma and PEX - a Pilot Study

Glaucoma

Austria
Roxane Laboratories

Completed

Bioequivalency Study of 5 mg Pilocarpine Tablets Under Fasting Conditions

Dry Mouth

United States
Alberta Health services
Ottawa Hospital Research Institute; Jewish General Hospital; CancerCare Manitoba and other collaborators

Completed

Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients

Cancer | Head and Neck Cancer

Canada
Roxane Laboratories

Completed

Bioequivalency Study of 5 mg Piolocarpine Tablets Under Fed Conditions

Dry Mouth

United States
Roxane Laboratories

Completed

Bioequivalency Study of 7.5 mg Pilocarpine Under Fed Conditions

Dry Mouth

United States
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Xerostomia in Patients With a Life-limiting Condition or Frailty

Xerostomia | Dry Mouth
Roxane Laboratories

Completed

Bioequivalency Study of 7.5 mg Pilocarpine Tablets Under Fasting Conditions

Dry Mouth

United States
Astellas Pharma Europe B.V.

Completed

A Study to Investigate the Effect of Oral Doses of Pilocarpine on Salivary Secretion and Static Pupillometry in Healthy Subjects

Healthy Subjects

United Kingdom
University of Kentucky

Completed

Efficacy of Cevimeline Versus Pilocarpine in the Secretion of Saliva

Dry Mouth

United States
University of California, San Diego
National Institutes of Health (NIH)

Terminated

Measuring Sweat Glucose of Patients With Diabetes - The ENGAGE Study

Diabetes Mellitus

United States
Jeong-seong Kwon

Completed

Effect of 0.1% Pilocarpine Mouthwash on Xerostomia

Xerostomia

Korea, Republic of

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