Search clinical trials for: Pixantrone (BBR 2778)

Total 1439 results

CTI BioPharma

Withdrawn

Dose-Escalation Study of Pixantrone Monotherapy in Pediatric Patients With Relapsed or Refractory Cancer

Lymphoma | Solid Tumor (Excluding CNS)

United States
CTI BioPharma

Terminated

Comparative Trial for Pixantrone in Combination With Rituximab in Indolent Non-Hodgkin's Lymphoma

Lymphoma, Follicular | Lymphoma, Mixed-Cell, Follicular | Lymphoma, Small Cleaved-Cell, Follicular | Lymphoma, Low-Grade

United States
CTI BioPharma

Completed

Dose Ranging Trial for Pixantrone in the FND-R Variant Regimen in Indolent Non-Hodgkin's Lymphoma

Lymphoma, Mixed-Cell, Follicular | Lymphoma, Small Cleaved-Cell, Follicular | Lymphoma, Low-Grade | Lymphoma, Small Lymphocytic

United States
Boehringer Ingelheim

Completed

Pharmacokinetics of BIBR 277 in Hypertensive Patients

Hypertension
CTI BioPharma

Completed

Pixantrone (BBR 2778) in Patients With Refractory Acute Myelogenous Leukemia (AML)

Acute Myelogenous Leukemia

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Pixantrone Dimaleate in Treating Patients With HER2-Negative Metastatic Breast Cancer

Breast Cancer

United States
Boehringer Ingelheim

Completed

Bioequivalence of BIBR 277 Tablet Compared With Capsule in Healthy Male Volunteers

Healthy
Kyowa Hakko Kirin UK, Ltd.

Completed

A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma

Multiple Myeloma | Chronic Lymphocytic Leukaemia | B-cell Non-Hodgkin's Lymphoma

United Kingdom
Aerpio Therapeutics

Completed

Safety and Pilot Efficacy of AKB-9778 in Subjects With Diabetic Macular Edema

Diabetic Macular Edema (DME)

United States
Boehringer Ingelheim

Completed

Bioequivalence of BIBR 277 Tablet (Mannitol Based) Compared With Capsule Formulation in Healthy Male Volunteers

Healthy
Johannes Gutenberg University Mainz
Roche Pharma AG; Servier

Completed

GOAL: GA101 Plus Pixantrone for Relapsed Aggressive Lymphoma

Lymphoma, Non-Hodgkin

Germany
Aerpio Therapeutics

Completed

Open Label Study to Assess the Efficacy and Safety of AKB-9778 in Subjects With Macular Edema Due to RVO

Retinal Vein Occlusion

United States
Merck Sharp & Dohme LLC

Completed

A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1)

Hepatitis C
Kinnate Biopharma

Recruiting

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

Melanoma | Non-small Cell Lung Cancer | Solid Tumor, Adult

United States, Australia, France, Spain, Taiwan, Korea, Republic of, China, Netherlands
Aerpio Therapeutics

Completed

Study to Assess the Absorption, Metabolism, Excretion and Pharmacokinetics of [14C]-AKB-9778

Healthy
Boehringer Ingelheim

Completed

Telmisartan/Hydrochlorothiazide (HCTZ) Fixed Dose Combination Compared to Its Monocomponents in Healthy Subjects

Healthy
Vedic Lifesciences Pvt. Ltd.

Recruiting

A Study to Evaluate the Efficacy of EQ-778 on Upper Respiratory Tract Health Status in Healthy Adults

Upper Respiratory Tract Infection

India
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Black Raspberry Confection in Preventing Oral Cancer in Healthy Volunteers

Healthy Volunteers

United States
Anne Beaven, MD
CTI BioPharma

Completed

IIT CTI Bendamustine, Rituximab, Pixantrone in Relapsed/Refractory B Cell Non-Hodgkin's Lymphoma (BRP)

Non-Hodgkin's Lymphoma

United States
Boehringer Ingelheim

Completed

BIBR 277 Capsules in Hypertensive Patients With Nephropathy

Hypertension
CTI BioPharma

Completed

Comparison of Pixantrone + Rituximab With Gemcitabine + Rituximab in Patients With Aggressive B-cell Non-Hodgkin Lymphoma or Follicular Grade 3 Lymphoma Who Have Relapsed After Therapy and Are Not Eligible for Stem Cell Transplant (PIX-R)

Diffuse Large B-cell Lymphoma | de Novo DLBCL | DLBCL Transformed From Indolent Lymphoma | Follicular Grade 3 Lymphoma

United States, Germany, Italy, United Kingdom, Hungary, France, Spain, Ukraine, Czechia, Austria, Belgium, Bulgaria, Denmark, Poland, Romania, Russian Federation, Slovakia
Ohio State University
National Cancer Institute (NCI); University of North Carolina, Chapel Hill; University...

Completed

Clinical Evaluation of Bioadhesive Gels for Oral Cancer Chemoprevention

Intraepithelial Neoplasia | Squamous Cell Carcinoma of Mouth

United States
CTI BioPharma

Withdrawn

Fludarabine and Rituximab With or Without Pixantrone in Treating Patients With Relapsed or Refractory Indolent Non-Hodgkin Lymphoma

Lymphoma | Leukemia

United States
Alios Biopharma Inc.

Terminated

Study of the Relative Oral Bioavailability of AL-3778 Tablets and Drug Interaction With Entecavir or Tenofovir Disoproxil Fumarate in Healthy Volunteers

Hepatitis B | Chronic Hepatitis B | Viral Hepatitis B

New Zealand
CTI BioPharma

Withdrawn

Pharmacokinetic and Safety Study of Pixantrone in Patients With Metastatic Cancer and Hepatic Impairment (Hepatic)

Metastatic Cancer

United States
CTI BioPharma

Withdrawn

Fludarabine, Pixantrone and Rituximab vs Fludarabine and Rituximab forRelapsed or Refractory Indolent NHL

Non-Hodgkin's Lymphoma

United States
Arizona State University
Christopher Wharton; Eric Bartholomae; April Incollingo; Maricarmen Vizcaino

Completed

Effect of Supplementary Dietary Protein (21g Per Day) on Lean Mass and Strength in Sedentary, Adult Vegetarians (MungBean)

Muscle Weakness

United States
Kyowa Hakko Kirin Pharma, Inc.
Kyowa Kirin Co., Ltd.

Completed

A Study of KW-2478 in Combination With Bortezomib in Subjects With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma

United States, Philippines, United Kingdom
Novira Therapeutics, Inc.

Completed

Safety and Efficacy Study of NVR 3-778 in Healthy Volunteers and Hepatitis B Patients

Chronic Hepatitis B

New Zealand
Novira Therapeutics, Inc.

Completed

Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patients

Chronic Hepatitis B

United States, Taiwan, Singapore, Korea, Republic of, China
EyePoint Pharmaceuticals, Inc.

Completed

The TIME-2b Study: A Study of AKB-9778 (Razuprotafib), a Novel Tie 2 Activator, in Patients With Non-Proliferative Diabetic Retinopathy (NPDR) (TIME-2b)

Nonproliferative Diabetic Retinopathy

United States
EyePoint Pharmaceuticals, Inc.

Completed

Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Saint Raphael Healthcare System

Completed

Measurement of Gastric Band Stoma Diameter

Obesity

United States
Bayer

Completed

A Study to Evaluate The Effects Of a Multivitamin/Mineral With Ginko In Subjects With Age Associated Memory Impairment

Age-Related Memory Disorders

United Kingdom
Ruhr University of Bochum

Completed

Tachosil for the Prevention of Symptomatic Lymph Cysts

Cervical Cancer | Endometrial Cancer

Austria, Germany
Aerpio Therapeutics

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic Solution

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Theradex

Unknown

BBR 3464 in Treating Patients With Metastatic Small Cell Lung Cancer That Has Not Responded to Previous Treatment

Lung Cancer

United States
Alios Biopharma Inc.

Withdrawn

A Study Evaluating AL-3778 in Combination With Peginterferon Alpha-2a in Chronic Hepatitis B Subjects

Hepatitis B, Chronic
Ahmed Mohamed Said Rozeik

Not yet recruiting

Evaluation of Bone Height Gain Following Trans-crestal Sinus Floor Elevation

Maxillary Sinus Disease

Egypt
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety and Efficacy Trial of Delamanid for 6 Months in Participants With Multidrug-resistant Tuberculosis

Multidrug-resistant Tuberculosis

South Africa, Estonia, Philippines, Peru, Lithuania, Latvia, Moldova, Republic of
The Dental Hospital of Zhejiang University School...

Recruiting

Radiographic Bone Volume Alteration After Jaw Cyst Enucleation With Different Bone Grafts

Jaw Cysts

China
Jackson Implant Surgery

Completed

Study Comparing Osseodensification With Standard Drilling (OD/SD)

Tooth Loss

United States
Shenyang Sunshine Pharmaceutical Co., LTD.

Unknown

rESP Medication With a Single Intravenous Administration and Dose Escalation to Explore the Tolerability ,Safety and Pharmacokinetic Characteristics

Chronic Renal Failure

China
Theradex

Unknown

Combination Chemotherapy in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

Lymphoma

United States
Chen Zhao
Shanghai Jiao Tong University School of Medicine; Children's Hospital of Fudan... and other collaborators

Completed

S-BLR Versus C-BLR for CI-IXT in Children (SCCIXT)

Convergence Insufficiency Intermittent Exotropia (CI-IXT)

China
Botanix Pharmaceuticals

Completed

A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

Hyperhidrosis

United States
Active Biotech AB

Completed

Exploratory Study of Changes in Disease Activity and Biomarkers With ABR-215757 in Patients With Mild Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

Denmark, Sweden
Theradex

Unknown

BBR 3464 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer That Cannot be Treated With Surgery

Pancreatic Cancer

United States
Theradex

Unknown

Pixantrone, Cytarabine, Methylprednisolone, and Cisplatin in Treating Patients With Aggressive Non-Hodgkin's Lymphoma in First Relapse

Lymphoma

United States, Puerto Rico
Kansas State University
MGP Ingredients, Inc.

Withdrawn

Long-term Consumption of Resistant Starch Type-4 (RS4)

Overweight or Obesity | Cholesterol, Elevated

United States

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