Search clinical trials for: Placebo Vehicle Punctum Plug

Total 925 results

Lahey Clinic

Completed

Lid Margin And Conjunctival Microbial Flora Following Punctum Occlusion

Dry Eye Syndrome

United States
Ocular Therapeutix, Inc.

Unknown

Non-Significant Risk Feasibility Study to Assess Retention and Replacement of the OTX Punctum Plug

Healthy Subjects
Ocular Therapeutix, Inc.

Completed

Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain After Cataract Surgery

Ocular Inflammation and Pain

United States
Mati Therapeutics Inc.

Completed

An Open-Label, Multi-Center, Clinical Study Evaluating the Effect of the NDE L68 StableFit® Punctal Plug on the Tear Lake

Dry Eye Syndromes

United States
Allergan

Completed

Safety and Efficacy of Punctal Plug Insertion in Patients With Dry Eye

Dry Eye

Singapore
Intravacc B.V.
Novotech (Australia) Pty Limited

Completed

Safety and Efficacy of Intranasal Administration of Avacc 10 Vaccine Against COVID-19 in Healthy Volunteers (ITV2002)

COVID-19

Australia
Tanta University

Completed

Quality of Life Improvement in Dry Eye Patients After Intense Pulsed Light Therapy Compared to Punctal Plugs

Evaporative Dry Eye

Egypt
University of New Mexico

Withdrawn

Punctal Plugs and Iodine Related Discomfort

Dry Eye Syndromes

United States
Galderma R&D

Completed

Efficacy and Safety Study of NP000888 in Subjects With Plaque and Nail Psoriasis

Psoriasis

Taiwan
Eisai Limited

Completed

A 12-Day Randomized, Blinded, Vehicle and Active Comparator-Controlled Study to Determine the Efficacy and Safety of Six Concentrations of Topical E6201 Gel in Subjects With Psoriasis Vulgaris

Psoriasis Vulgaris

Germany
University of Oklahoma

Completed

The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection

Dry Eye | Dry Eye Syndromes | Ocular Surface Disease

United States
Trefoil Therapeutics, Inc.

Completed

A Phase 1/ Phase 2 Study of TTHX1114(NM141) (INTREPID)

Endothelial Dysfunction | Corneal Endothelial Dystrophy | Pseudophakic Bullous Keratopathy | Fuchs Endothelial Corneal Dystrophy

United States
Celularity Incorporated
Celgene Corporation

Terminated

Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Active Rheumatoid Arthritis

Rheumatoid Arthritis

United States
New York Medical College
U.S. Army Medical Research and Development Command; Westchester Medical Center

Unknown

Intranasal Neuropeptide Y in Clinical Trial in Level Two Trauma Patients for PTSD and Acute Stress Disorder

Stress Disorders, Post-Traumatic | Stress Disorders, Traumatic, Acute

United States
Taro Pharmaceuticals USA

Completed

Clinical Study to Evaluate the Efficacy and Safety of DSXS in Patients With Mild to Moderate Plaque Psoriasis

Plaque Psoriasis

United States
Integra LifeSciences Corporation
Integrium

Terminated

Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers (STRIDE 1)

Diabetic Foot Ulcers

United States
Raziel Therapeutics Ltd.

Completed

RZL-012 for Dercum's Disease Lipomas

Dercum's Disease Lipomas

United States
Taro Pharmaceuticals USA

Completed

A Randomized Double Blind Vehicle Controlled Dose Ranging Parallel Design Multiple Site Clinical Study

Plaque Psoriasis
Benha University

Completed

Outcome of Omega 3 FA and Punctal Plugs on Ocular Surface Disease

Ocular Surface Disease

United Arab Emirates
Shaare Zedek Medical Center

Unknown

Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug -EXP-LP (EXP-LP)

Ocular Hypertension | Glaucoma | IOP

Israel
Taro Pharmaceuticals USA

Completed

Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi-Site Phase 2b Clinical Study

Onychomycosis

United States
Pfizer

Completed

Crisaborole for Chinese and Japanese Subjects (≥2 Years of Age) With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

China, Japan, Korea, Republic of
Microbion Corporation

Completed

A Trial to Assess Safety and Efficacy of Topical MBN-101 in Patients With Moderate/ Severe DFI

Diabetic Foot Infection

United States
Amber Ophthalmics, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED (NEXPEDE-1)

Persistent Corneal Epithelial Defect

United States
Hapten Sciences, Inc.
Milton S. Hershey Medical Center

Not yet recruiting

A Safety, Tolerability, and Dermal Reactogenicity Study of PDC-APB

Contact Dermatitis
Helixmith Co., Ltd.

Terminated

Safety and Efficacy Study of Engensis (VM202) in the Treatment of Chronic Non-Healing Foot Ulcers

Foot Ulcer, Diabetic

United States
Novan, Inc.

Completed

A Phase 1, 3 Day Study of Safety and Tolerability of NVN1000 Topical Gel in Healthy Volunteers

Acne Vulgaris

United States
Incyte Corporation

Completed

A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children With Atopic Dermatitis (TRuE-AD3)

Atopic Dermatitis

United States, Canada
Bayer

Completed

Dose Escalation of Different Concentrations of ZK 245186 in Atopic Dermatitis

Atopic Dermatitis

South Africa
Taro Pharmaceuticals USA

Completed

Study to Evaluate Efficacy and Safety of the Topical Product in Patients With Mild to Severe Scalp Psoriasis

Scalp Psoriasis
Novan, Inc.
Novella Clinical

Completed

A Study Assessing the PK, PD, Safety, and Tolerability of SB414 in Psoriasis

Psoriasis

United States
Sophiris Bio Corp

Completed

Randomized, Double-Blind, Vehicle-Controlled, Multicenter Safety and Efficacy Study of Intraprostatic PRX302 for LUTS BPH (PLUS-1)

Benign Prostatic Hyperplasia

United States, Australia, Canada, Russian Federation, Ukraine, New Zealand
Centre Hospitalier Sud Francilien

Completed

Impact of the Puncture of the RP6 Point on the Ampliation and Injuries of the Perineum During Childbirth (PELVPUNCTURE)

Perineum; Injury

France
Allergan

Terminated

A Safety and Efficacy Study of AGN-214868 in Patients With Postherpetic Neuralgia

Neuralgia, Postherpetic

United States, Austria, Poland, Germany
PellePharm, Inc.

Completed

Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell Carcinomas (BCC)

Basal Cell Carcinomas

United States
Taro Pharmaceuticals USA

Completed

Phase III Clinical Study in Patients With Mild to Severe Scalp Psoriasis

Scalp Psoriasis

United States
Peplin

Completed

A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)

Actinic Keratosis

United States, Australia
Rabin Medical Center

Unknown

A Comparison Between Bandage Contact Lens, Punctal Plugs and Standard Measures in Preventing Corneal Injuries (COMLENPLSTAN)

Contact Lens and Punctal Plug in Preventing Corneal Injuries

Israel
Novan, Inc.
Chiltern International Inc.

Completed

P3 Study in Acne Comparing Once Daily SB204 and Vehicle

Acne Vulgaris

United States
PRG Science & Technology Co., Ltd.
Amarex Clinical Research

Completed

Phase I Study of Progerinin in Healthy Volunteers

Hutchinson-Gilford Progeria Syndrome | Werner Syndrome

United States
Taro Pharmaceuticals USA

Completed

A Study Comparing the Efficacy of TA103 and the Placebo Control in the Treatment of Interdigital Tinea Pedis.

Tinea Pedis

United States
PellePharm, Inc.

Completed

Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas in Gorlin Syndrome Patients

Basal Cell Nevus Syndrome

United Kingdom
HenKan Pharmaceutical Co., Ltd.

Completed

Comparison Study With E-DO in Chronic Hand Dermatitis

Chronic Hand Dermatitis

Taiwan
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

A Phase 2 Study of QLM3003 Ointment in Participants With Mild or Moderate Atopic Dermatitis

Atopic Dermatitis

China
BiomX, Inc.

Active, not recruiting

Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infection

Cystic Fibrosis | Chronic Pseudomonas Aeruginosa Infection

United States, Israel, Spain, Czechia, Netherlands
Novan, Inc.
Chiltern International Inc.

Completed

P3 Study Comparing Once Daily SB204 and Vehicle Gel in Acne

Acne Vulgaris

United States
Medicis Global Service Corporation

Completed

Safety and Efficacy Study to Treat Bacterial Vaginosis

Bacterial Vaginosis

United States
Rabin Medical Center
Alpha Net Co. Ltd.

Completed

Perforated Punctal Plugs for Treatment of Papillary Conjunctivitis in Otherwise Healthy Patients

Conjunctivitis | Epiphora

Israel
Dompé Farmaceutici S.p.A

Completed

A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye

Dry Eye Syndrome

United States
Reistone Biopharma Company Limited

Active, not recruiting

Evaluate the Efficacy and Safety of Topical SHR0302 Ointment in Patients With Mild-to-Moderate Atopic Dermatitis (MARBLE-23)

Atopic Dermatitis

China

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