Search clinical trials for: Placebo and AIR001 Inhalation Solution (Expansion arm)

Total 5325 results

Aires Pharmaceuticals, Inc.

Completed

Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers (AIR001-CS02)

Pulmonary Arterial Hypertension

United States
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI); Aires Pharmaceuticals, Inc.

Completed

Inhaled Sodium Nitrite on Heart Failure With Preserved Ejection Fraction

Heart Failure

United States
Aires Pharmaceuticals, Inc.

Terminated

A Phase 2 Study to Determine the Safety and Efficacy of AIR001 in Subjects With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Australia, Hungary
Aires Pharmaceuticals, Inc.

Terminated

Long-term Study of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension Who Completed AIR001-CS05

Pulmonary Arterial Hypertension

United States, Australia, Hungary
Arrowhead Pharmaceuticals

Recruiting

Study of ARO-MMP7 Inhalation Solution in Healthy Subjects and Patients With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

New Zealand, Spain
Pharmosa Biopharm Inc.
Novotech (Australia) Pty Limited

Recruiting

Safety, Tolerability and Pharmacokinetics of L608 in Healthy Adults

Pulmonary Arterial Hypertension

Australia
Pharmosa Biopharm Inc.
PPD

Completed

Single Ascending Dose Study for Evaluation of Safety, Tolerability and Pharmacokinetics of L606

Pulmonary Arterial Hypertension

United States
Hangzhou Sciwind Biosciences Co., Ltd.

Completed

Phase Ia Study of XW001 in Healthy Adult Subjects

Respiratory Syncytial Virus Infections

China
Bitop AG

Completed

Efficacy and Feasibility of Ectoin® Inhalation Solution in Inflammatory Obstruction and Ageing of the Lung (EFECT)

COPD | Particulate Matter Induced Inflammation of the Lung

Germany
Mylan Pharma UK Ltd.

Completed

Revefenacin in Chinese Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease(COPD)

COPD

China
Meiji Seika Pharma Co., Ltd.

Completed

Pharmacokinetics and Safety Study of ME1100 in Healthy Volunteers

Healthy

United States
Spyryx Biosciences, Inc.

Completed

An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis ((HOPE-1))

Cystic Fibrosis

United Kingdom, Canada, France, Italy, Portugal
Allakos Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AK001

Atopy

United States
Merck Sharp & Dohme LLC

Completed

Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis (CF) Lung Disease

Cystic Fibrosis

United States, Australia, Canada, New Zealand
Boehringer Ingelheim

Completed

Dose Extension Study of BIIX 1 XX in Healthy Young Male Volunteers

Healthy
Gerard Turino

Completed

Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency

Emphysema | Alpha 1-Antitrypsin Deficiency

United States, Canada
Kexing Biopharm Co., Ltd.

Recruiting

Human Interferon α1b Inhalation Solution Against Respiratory Syncytial Virus in Children With Lower Respiratory Tract Infections

Respiratory Syncytial Virus Infections

China
Pfizer

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
Northwestern University
Genentech, Inc.

Unknown

Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy

Head and Neck Cancer

United States
BioMarck Pharmaceuticals, Ltd.
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness and Safety of BIO-11006 Inhalation Solution to Treat the Overproduction of Mucus and Inflammation in COPD (BREATH-1)

Chronic Obstructive Pulmonary Disease | COPD

United States
Sunovion Respiratory Development Inc.

Completed

Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [ie, Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered With an Electronic eFlow Nebulizer System in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
Sunovion Respiratory Development Inc.

Completed

Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [i.e., Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered Using an eFlow Nebulizer in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease
Merck Sharp & Dohme LLC

Completed

Study of Denufosol Inhalation Solution in Patients With Mild Cystic Fibrosis Lung Disease

Cystic Fibrosis
Olga Tyumina
Clinics of the Federal State Budgetary Educational Institution SSMU; Samara...

Unknown

Safety and Efficiency of Method of Exosome Inhalation in COVID-19 Associated Pneumonia (COVID-19EXO2)

COVID-19 | Covid19 | SARS-CoV-2 PNEUMONIA

Russian Federation
Aires Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States
National Jewish Health

Unknown

Use of DNAse in Neutrophilic Asthma

Neutrophilic Asthma

United States
State-Financed Health Facility "Samara Regional...
Clinics of the Federal State Budgetary Educational Institution SSMU; Samara...

Completed

Evaluation of Safety and Efficiency of Method of Exosome Inhalation in SARS-CoV-2 Associated Pneumonia. (COVID-19EXO)

COVID-19 | Covid19 | SARS-CoV-2 PNEUMONIA

Russian Federation
University of North Carolina, Chapel Hill
United Therapeutics

Terminated

Treprostinil Sodium Inhalation for Patients At High Risk for ARDS

Respiratory Distress Syndrome, Adult

United States
Erik Allen Jensen
University of Florida

Active, not recruiting

Inhaled Tobramycin in BPD

Bronchopulmonary Dysplasia

United States
Chimerix

Terminated

A Study Designed to Evaluate ODSH in Subjects With Exacerbations of COPD (COPD)

Chronic Obstructive Pulmonary Disease

United States, Canada, Belgium, Poland, Germany
Mylan Pharma UK Ltd.

Completed

Fasting Bioavailability Study of Mylan's Revefenacin Inhalation Solution

Healthy Volunteers Bioavailability Study

China
Merck Sharp & Dohme LLC

Terminated

Study 08-114 Open-label Extension of Study 08-110 - A Multi-Center Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis Lung Disease (P08642) (DEFY)

Cystic Fibrosis
Bitop AG

Active, not recruiting

Multicentre Post-market Study of Ectoin® Inhalation Solution in Treatment of Asthma. (EIL-AST)

Asthma

Poland
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of BEA 2180 BR in Healthy Male Volunteers

Healthy
Merck Sharp & Dohme LLC

Terminated

Study of Denufosol Inhalation Solution in Patients With Mild to Moderate Cystic Fibrosis Lung Disease

Cystic Fibrosis
United Therapeutics

Completed

Clinical Investigation Into Inhaled Treprostinil Sodium in Patients With Severe Pulmonary Arterial Hypertension (PAH) (TRIUMPH)

Pulmonary Hypertension

United States, Israel, Austria, United Kingdom, Belgium, France, Germany, Ireland, Italy, Spain
GlaxoSmithKline

Completed

GSK573719 IV Enabling Study

Pulmonary Disease, Chronic Obstructive

United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study in Adult and Pediatric Patients With Cystic Fibrosis

Cystic Fibrosis
University College, London

Completed

Nebulised Dornase Alfa for Treatment of COVID-19 (COVASE)

Hypoxia | COVID19

United Kingdom
University of Missouri-Columbia

Completed

Dornase Alfa for ARDS in Patients With Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) (DORNASESARS2)

SARS-CoV 2 | ARDS

United States
Dankook University
Wonkwang University; University of Ulsan

Completed

A Prospective Trial of Aggressive Hydration Strategy to Reduce Post-ERCP Pancreatitis

Post-ERCP Acute Pancreatitis

Korea, Republic of
Sunovion Respiratory Development Inc.

Completed

A Clinical Study to Investigate if a Single Dose of an Approved Drug Product (Glycopyrrolate Inhalation Solution) Reduces Trapped Air in the Lungs of Participants With Chronic Obstructive Pulmonary Disease.

Chronic Obstructive Pulmonary Disease (COPD)

United States
Alector Inc.

Completed

A First in Human Study in Healthy Volunteers and in Participants With Frontotemporal Dementia With Granulin (GRN) Mutation

Healthy | Frontotemporal Dementia

United States, Canada, United Kingdom
Pulmotect, Inc.
United States Department of Defense

Completed

The Use PUL-042 to Reduce the Infection Rate and Progression to COVID-19 in Adults Exposed to SARS-CoV-2

COVID-19

United States
Medical Center Alkmaar

Completed

Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis (BATTLE)

Non-CF Bronchiectasis

Netherlands
Meiji Seika Pharma Co., Ltd.

Completed

A Study to Assess the Pharmacokinetic Profile, the Safety, and the Tolerability of ME1100 Inhalation Solution in Patients With Mechanically Ventilated Bacterial Pneumonia

Pneumonia, Bacterial

United States
Children's Hospital of Philadelphia

Completed

Hypertonic Saline for Acute Bronchiolitis

Saline Solution, Hypertonic | Bronchiolitis, Viral

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy of 3% Hypertonic Saline in Acute Viral Bronchiolitis (GUERANDE)

Acute Viral Bronchiolitis

France
Merck Sharp & Dohme LLC

Completed

A Study to Diagnose Lung Cancer by Sputum Cytology (01-312)

Lung Cancer
Fondation Ophtalmologique Adolphe de Rothschild
University Hospital, Strasbourg, France; Centre Hospitalier Régional Metz-Thionville

Terminated

Efficacy and Safety of aerosolizedDornase Alfa Administration in Patients With COVID19 Induced ARDS (COVIDORNASE) (COVIDORNASE)

COVID-19 | Acute Respiratory Distress Syndrome

France

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