Search clinical trials for: Placebo (for K-877)

Total 2580 results

Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Normal Renal Function

Severe Hypertriglyceridemia

United States, Hungary, Belarus, Bulgaria, Czechia, Georgia, Poland, Russian Federation, Ukraine
Kowa Research Institute, Inc.

Completed

Compare the Pharmacokinetic of K-877 Controlled Release (CR) and Immediate Release (IR) Tablets in Healthy Adults.

Healthy

United States
Kowa Research Institute, Inc.
Brigham and Women's Hospital

Terminated

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT) (PROMINENT)

Dyslipidemia | Type2 Diabetes

United States, Spain, Canada, Hungary, Netherlands, Brazil, Bulgaria, Poland, Israel, Russian Federation, Ukraine, Denmark, Czechia, South Africa, Argentina, Mexico, United Kingdom, Romania, Germany, India, Slovakia, Japan, Colombia, ... and more
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

Severe Hypertriglyceridemia

United States, Czechia, Belarus, Hungary, Russian Federation, Poland, Bulgaria, Georgia, Ukraine
Kowa Research Institute, Inc.

Completed

Study to Investigate the Efficacy and Pharmacokinetic Profile of K-877-ER Compared to K-877-IR

Dyslipidemia

United States
Kowa Company, Ltd.

Completed

A Clinical Pharmacology Study of K-877 Controlled Release Tablet

Dyslipidemias

Japan
Kowa Research Institute, Inc.

Completed

Study to Assess the Food Effect of K-877 in Healthy Adult Volunteers

Healthy

United States
Kowa Company, Ltd.

Completed

A Study of Pemafibrate in Patients With Nonalcoholic Fatty Liver Disease (NAFLD)

Non-Alcoholic Fatty Liver Disease

Japan
Kowa Company, Ltd.

Recruiting

A Phase III Confirmatory Study of K-877 (Pemafibrate) in Patients With Hypercholesterolemia and Statin Intolerance

Hypercholesterolemia

Japan
Kowa Company, Ltd.

Recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of K-877 in Chinese Patients With High TG and Low HDL-C

Hyperlipidemia

China
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study to Assess the Effects of Multiple-Dose Administration of K-877 on the Pharmacodynamics and the Pharmacokinetics of Multiple-Dose Administration of Warfarin in Healthy Adult Volunteers

Healthy

United States
Kowa Research Institute, Inc.

Completed

A Thorough Corrected QT Interval Trial

Dyslipidemia

United States
Kowa Company, Ltd.

Completed

A Phase III Confirmatory Study of K-877 Extended Release Tablet

Dyslipidemias

Japan
Kowa Company, Ltd.

Completed

A Phase III Long Term Study of K-877 Extended Release Tablet

Dyslipidemias

Japan
Global Alliance for TB Drug Development

Completed

Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
Bridge Biotherapeutics, Inc.
KCRN Research, LLC

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BBT-877 in Healthy Subjects

Idiopathic Pulmonary Fibrosis

United States
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Tolerability, and Weight Loss Efficacy of K-757 Alone and in Combination With K-833

Obesity

United States
Kallyope Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes

Obesity | Type 2 Diabetes Mellitus (T2DM)

United States
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes

Obesity | Type 2 Diabetes Mellitus in Obese

United States
Kowa Company, Ltd.

Completed

K-924 Phase III Confirmatory Study

Hypercholesterolemia

Japan
RenJi Hospital

Unknown

The Efficacy and Safety of K-001 in the Treatment of Advanced Pancreatic Cancer

Pancreatic Cancer

China
Kowa Research Institute, Inc.

Completed

Study Comparing the Pharmacokinetics, Pharmacodynamics, and Safety of K-312 in Healthy Adult Volunteers

Safety and Tolerability

United States
Kowa Research Institute, Inc.

Completed

A Trial of the Safety and Efficacy of K-604 for the Treatment of Atherosclerosis

Atherosclerosis

United States
Kowa Company, Ltd.

Completed

A Study to Evaluate the Safety of K-755 in Healthy Volunteers

Healthy

Australia
Bridge Biotherapeutics, Inc.
KCRN Research, LLC

Completed

Evaluate Safety, Pharmacokinetics and Pharmacodynamics of BBT-877 in Healthy Japanese Male

Healthy Participants

United States
Kolon Life Science

Unknown

The Efficacy and Safety of Invossa K Injection in Patients Diagnosed With Knee Osteoarthritis

Osteoarthritis

Korea, Republic of
Kowa Research Institute, Inc.

Completed

Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of K-312 in Healthy Subjects

Hyperlipidemia

United States
Bio-K Plus International Inc.
Centre hospitalier de l'Université de Montréal (CHUM)

Terminated

Study of Bio-K+® in the Reduction of the Risk of Clostridium Difficile Infection and Antibiotic Associated Diarrhea

Clostridium Difficile Infection | Antibiotic Associated Diarrhea

Canada
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study in Health Adult Volunteers

Healthy

United States
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 in Healthy Overweight/Obese Volunteers

Obesity

United States
Instituto Mexicano del Seguro Social
Rodolfo Guardado Mendoza; Marco Antonio Ocampo Apolonio; Texar Alfonso Pereyra...

Completed

Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients

Coronary Calcification

Mexico
Urovant Sciences GmbH
Ion Channel Innovations

Terminated

Safety Study of hMaxi-K Gene Transfer to Treat Overactive Bladder and Detrusor Overactivity

Overactive Bladder

United States
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Primary Biliary Cholangitis

United States, Japan
Urovant Sciences GmbH
Ion Channel Innovations

Completed

Phase 1 Study With OAB Assessing the Safety and Activity of hMaxi-K Gene Transfer (OAB)

Overactive Bladder

United States
Takeda

Terminated

Study of TAK-875 in Adults With Type 2 Diabetes and Cardiovascular Disease or Risk Factors for Cardiovascular Disease

Cardiovascular Disease | Type 2 Diabetes

United States, France, Poland, Ukraine, Germany, Hong Kong, Taiwan, Argentina, Israel, Mexico, Bulgaria, Malaysia, Romania, Canada, Korea, Republic of, New Zealand, Peru, Estonia, Philippines, Russian Federation, Czech Republic, H... and more
Bio-K Plus International Inc.
ethica Clinical Research Inc.

Completed

Efficacy of BIO-K+ CL1285® Prophylaxis in the Prevention of Traveler's Diarrhea in Adults

Diarrhea

Canada
Urovant Sciences GmbH

Completed

URO-902 in Female Subjects With Overactive Bladder and Urge Urinary Incontinence

Overactive Bladder With Urge Urinary Incontinence

United States
Takeda

Terminated

Study to Evaluate the Efficacy and Safety of Daily Oral TAK-875 25 and 50mg in Asia Pacific Adults With Type 2 Diabetes (GRAND-307)

Type 2 Diabetes Mellitus

Taiwan, China, Korea, Republic of, New Zealand, Australia
Evolva SA

Terminated

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of EV-077 in Type 2 Diabetic Subjects

Type 2 Diabetes

Germany
Bio-K Plus International Inc.
Centre Hospitalier Pierre-Le Gardeur

Withdrawn

Evaluation of the Efficacy of Bio-K+ Cl-1285® In the Nasal Decolonization of Methicillin Resistant Staphylococcus Aureus (MRSA) Carrier Patients (MRSA)

MRSA Colonization

Canada
Boryung Pharmaceutical Co., Ltd

Completed

Efficacy, Safety and Pharmacodynamic/Pharmacokinetic Study of Fimasartan (BR-A-657•K) (Fimasartan)

Essential Hypertension
Urovant Sciences GmbH
Dasman Diabetes Institute; Ion Channel Innovations

Completed

Phase 2A Clinical Trial Evaluating the Potential Activity and Safety of hMaxi-K Gene for ED

Erectile Dysfunction

Kuwait
Istituto Clinico Humanitas

Unknown

Comparing Two Different Embryo Transfer Catheters (CATH)

Infertility

Italy
Kowa Research Institute, Inc.

Completed

A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye Disease

Dry Eye Disease

United States
Takeda

Completed

Double-blind Comparative Study of TAK-875

Diabetes Mellitus

Japan
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study in Healthy Adult Volunteers

Healthy

United States
Kowa Research Institute, Inc.

Completed

Study to Demonstrate the Bioequivalence of Single Oral Administration of K-001 Relative to Single Oral Coadministration of Separate Tablets of K-877-ER and CSG452

Healthy

United States
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study to Assess the Effects of Multi Dose Clopidogrel on the Pharmacokinetics of Single-Dose K-877 in Healthy Adult Volunteers

Healthy

United States
Kowa Research Institute, Inc.

Completed

Drug-Drug Interaction Study in Healthy Adult Volunteers

Healthy

United States
Bridge Biotherapeutics, Inc.

Recruiting

To Evaluate the Efficacy, Safety, and Tolerability of BBT-877 in Patients With IPF

Idiopathic Pulmonary Fibrosis

United States, Korea, Republic of, Australia, Israel, Poland

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