Search clinical trials for: Polypill (atorvastatin, amlodipine, losartan, and hydrochlorothiazide)

Total 227 results

Chong-Jin Kim
Hanmi Pharmaceutical Company Limited

Completed

Comparison of Effects Between Amlodipine and Hydrochlorothiazide in Combination With Losartan on 24-hr Central Blood Pressure in Hypertensive Patients

Hypertension

Korea, Republic of
Vanderbilt University

Completed

The SCCS Polypill Pilot Trial

Hypertension | Hyperlipidemia

United States
Hanmi Pharmaceutical Company Limited

Completed

Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease

Hypertension | Aortic Stenosis | Aortic Regurgitation | Left Ventricular Hypertrophy | LVM

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

Efficacy/Safety of Amlodipine Plus Losartan Versus Amlodipine in Patients With Stage 2 Hypertension

Hypertension

Korea, Republic of
Azidus Brasil

Completed

Clinical Assessment Of Association Pharmacokinetics Atorvastatin + Losartana + Hydrochlorothiazide

Healthy Subjects

Brazil
Merck Sharp & Dohme LLC

Completed

MK-0954E Study in Participants With Hypertension (MK-0954E-357)

Hypertension
The University of The West Indies
Caribbean College of Family Physicians

Withdrawn

Phase 4 Study of the Efficacy of Losartan Based Therapy in Hypertensives With and Without Diabetes

Hypertension | Diabetes Mellitus

Jamaica
Shanghai Jiao Tong University School of Medicine

Recruiting

Efficacy and Safety of a Single-pill Fixed Combination of Sufficient Losartan/Hydrochlorothiazide in Chinese Hypertensive Patients

Hypertension

China
Hanmi Pharmaceutical Company Limited

Completed

Efficacy/Safety of Amlodipine Plus Losartan Versus Amlodipine in Patients With Essential Hypertension

Hypertension

Korea, Republic of
Yokohama City University Medical Center

Completed

Kanagawa Combination Anti-hypertensive Therapy (K-CAT)

Hypertension

Japan
Daiichi Sankyo, Inc.

Completed

Parallel-Group Comparison of Olmesartan (OLM), Amlodipine (AML) and Hydrochlorothiazid (HCTZ) in Hypertension

Essential Hypertension

Italy, Poland, Ukraine, Germany, Spain, Bulgaria, Romania, Denmark, Belgium, Netherlands, Russian Federation, Hungary, Slovakia, Czechia, Latvia
Hotel Dieu de France Hospital

Unknown

Fixed-Free HTN Trial

Hypertension

Lebanon
University Hospital, Strasbourg, France

Suspended

Specific Blockage of Angiotensine 2 and Podocyturia in Glomerular Nephropathies With Hypertension and Proteinuria

Hypertension | End Stage Renal Disease | Proteinuria

France
Shanghai WiseGain Medical Devices Co., Ltd.

Unknown

Randomized Controlled Trial of Renal Denervation for Resistant Hypertension

Hypertension

China
GlaxoSmithKline

Completed

Study to Determine the Bioequivalence of Two Fixed Dose Combination (FDC) Tablet Formulations of Amlodipine and Losartan FDC5/50 and FDC5/100 Under Fasting Conditions

Hypertension

South Africa
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Randomized Study To Evaluate Efficacy And Safety Of A Fixed Combination Therapy Of Amlodipine And Atorvastatin

Hypertension | Hypercholesterolemia

Japan
Columbia University

Completed

N-of-1 Trials for Blood Pressure Medications in Adults

Hypertension | High Blood Pressure

United States
Organon and Co

Completed

Antihypertensive Efficacy and Safety of Approved Drugs in Japanese Patients With Essential Hypertension (Banyu Study)(0954A-302)

Hypertension
Daiichi Sankyo, Inc.

Completed

Hydrochlorothiazide as add-on to Olmesartan/Amlodipine in Hypertension

Essential Hypertension

France, Poland, Ukraine, Belgium, Germany, Spain, Bulgaria, Romania, Denmark, Russian Federation, Netherlands, Austria, Slovakia, Czechia
University of Cambridge
British Heart Foundation

Unknown

Monotherapy Versus Dual Therapy for Initial Treatment for Hypertension (Pathway 1)

Essential Hypertension | Hypertension, Resistant to Conventional Therapy

United Kingdom
Organon and Co

Terminated

A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension (0954A-327)

Hypertension
Organon and Co

Completed

Bioequivalence of Losartan and Hydrochlorothiazide (HCTZ) Combination Tablet and Coadministration of Its Components (0954A-306)

Hypertension
Novartis

Completed

Pharmacokinetic Drug Interaction Study Following Co-administration of Valsartan, Hydrochlorothiazide and Amlodipine in Patients With Hypertension

Hypertension

India
Organon and Co

Completed

Efficacy of Losartan + Amlodipine Compared to Amlodipine Alone in the Treatment of Uncontrolled High Blood Pressure (MK-0954F-399)

Hypertension
Teva Pharmaceuticals USA

Completed

Losartan Potassium/Hydrochlorothiazide 100/25 mg Tablets in Healthy Subjects Under Fasting Conditions

Healthy

United States
EMS

Suspended

Comparison of Losartan Associated With Indapamide Versus Hyzaar® in the Hypertension Treatment

Hypertension

Brazil
Yonsei University

Completed

Pharmacokinetic Drug Interactions Between Single and Concomitant Administrations of Amlodipine, Losartan, and Hydrochlorothiazide in Subjects With (Pre)Hypertension

Essential Hypertension

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

Efficacy and Safety of Amlodipine and Losartan in Patients With Essential Hypertension

Hypertension

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

Efficacy/Safety of Amlodipine Plus Losartan Versus Losartan in Patients With Essential Hypertension

Hypertension

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

A Bioequivalence Study of Amlodipine Plus Losartan Versus Amlodipine and Losartan

Healthy

Czech Republic
Hanmi Pharmaceutical Company Limited

Completed

A Bioequivalence Study of Amlodipine Plus Losartan Versus Amlodipine and Losartan

Healthy

Czech Republic
Novartis

Completed

Valsartan/Amlodipine As Compared to Losartan Treatment in Stage 2 Systolic Hypertension (EXALT)

Stage 2 Systolic Hypertension

United States
Hanmi Pharmaceutical Company Limited

Completed

The Efficacy and Safety Study of Anti-hypertension Combination Drug in Patients Uncontrolled With Monotherapy.

Hypertension
Boehringer Ingelheim

Completed

PROBE Parallel 6-week Treatment Comparing Telmisartan/Hydrochlorothiazide (HCT) (40/12.5 or 80/12.5) With Losartan/HCT (50/12.5) Using Ambulatory Blood Pressure Monitoring (ABPM)

Hypertension

United States
IlDong Pharmaceutical Co Ltd

Completed

Efficacy and Safety of TAH Combination in Comparison With Telmisartan/Amlodipine Combination for Essential Hypertension Patients

Essential Hypertension

Korea, Republic of
Shanghai Jiao Tong University School of Medicine

Recruiting

Intensive Management of Blood Pressure and Cholesterol in Elderly Chinese With Hypertension and Atrial Fibrillation

Hypertension | Atrial Fibrillation

China
Organon and Co

Completed

BP-EASE -Effectiveness of Losartan 50 mg/Hydrochlorothiazide (HCTZ) 12.5 mg Versus Valsartan 80 mg/HCTZ 12.5 mg Titrated as Needed in Patients With Essential Hypertension Not Controlled on Monotherapy (0954A-333) (EASE)

Hypertension
University of Abuja
Imperial College London; University College Hospital, Ibadan; University of Nairobi and other collaborators

Completed

Comparison of Three Combination Therapies in Lowering Blood Pressure in Black Africans (Creole)

Hypertension

Nigeria
Novartis

Completed

Aliskiren/Amlodipine/Hydrochlorothiazide (HCTZ) Versus Aliskiren/Amlodipine in US Minority Patients With Stage II Systolic Hypertension (ASCENT)

Hypertension

United States
Yonsei University

Completed

Randomized, Open Labeled Clinical Trial to Compare the Effectiveness of Amlodipine/Valsartan vs Hydrochlorothiazide/Telmisartan on Glucose Tolerance in Patients With Hypertension With Metabolic Syndrome

Hypertension

Korea, Republic of
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Open Label Study Assessing Effectiveness Of Amlodipine/Atorvastatin In Subjects With Hypertension and Dyslipidaemia (JEWEL I)

Hypertension | Dyslipidemia

Canada, United Kingdom
Shanghai Jiao Tong University School of Medicine

Recruiting

Blood Pressure and Lipids Reduction in High Risk Elderly Patients With Isolated Systolic Hypertension

Isolated Systolic Hypertension

China
University of Pavia

Unknown

Valsartan and Amlodipine Compared to Losartan and Amlodipine in Hypertensive Patients

Essential Hypertension

Italy
Boehringer Ingelheim

Completed

A Randomized, Double-blind, Parallel-group Assessment of the Safety and Efficacy of Telmisartan 40mg Plus Hydrochlorothiazide 12.5mg (Micardis Plus) in Comparison With Losartan 50mg Plus Hydrochlorothiazide 12.5mg in Taiwanese Patients With Mild to Moderate Hypertension

Hypertension

Taiwan
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Olmesartan Medoxomil Versus Losartan in Elderly and Very Elderly

Essential Hypertension

Germany
Organon and Co

Completed

MK0954A-264 Filter Study (0954A-264)(COMPLETED)

Mild to Severe Hypertension
Novartis Pharmaceuticals

Terminated

A Randomized Controlled Trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly People (APOLLO)

Cardiovascular Events

Colombia, India, South Africa, Canada, Spain, Hungary, United States, Germany, Ireland, Argentina, Philippines, Brazil, Sweden, Malaysia, Chile, Israel, Czech Republic, Netherlands
GlaxoSmithKline

Completed

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Amlodipine and Losartan in Health Volunteers

Hypertension

Australia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Amlodipine/Atorvastatin Combination to Reduce the Health Risk of High Blood Pressure and High Cholesterol Levels (GEMINI-AALA)

Hypertension | Hyperlipidemia

Brazil, Turkey, Taiwan, Argentina, India, Philippines, Singapore, Thailand, Australia, Chile, South Africa, Jordan, Korea, Republic of, Lebanon, United Arab Emirates, Malaysia, Peru, Israel, Indonesia, Guatemala, Hong Kong, Kuwait, ... and more
Damanhour University

Completed

Pharmacokinetic Interactions of Losartan and Hydrochlorothiazide (PKLH)

Healthy Normotensive Participants

3

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