Search clinical trials for: Protamine

Total 342 results

Montreal Heart Institute
Organon

Completed

Cardiac Surgery: In Vivo Titration of Protamine (Protamine)

Bleeding

Canada
University of Miami

Completed

Optimal Protamine Dosing for Heparin Reversal Following Cardiopulmonary Bypass

Coagulation; Intravascular

United States
University of Michigan

Completed

Use of Protamine for Heparin Reversal After Catheter Ablation of Atrial Fibrillation

Atrial Fibrillation | Catheter Ablation

United States
University of Liege

Not yet recruiting

Impact of Protamine Dose Reduction on Platelet Aggregation After Extracorporeal Circulation for Minimally Invasive Aortic Valve Replacement Surgery

Protamine Adverse Reaction | Protamine Dose
Lawson Health Research Institute

Unknown

Systematic Evaluation of Protamine Doze in Cardiac Surgery (HART)

Cardiac Surgery With Cardiopulmonary Bypass

Canada
Mustafa Kemal University

Completed

Serum Tryptase Levels During Cardiac Surgery, Diagnosis and Treatment Decisions for Allergic Reactions

Protamine Adverse Reaction | Protamine Allergy

Turkey
Medical University of Warsaw

Completed

Protamine Sulfate During Transcatheter Aortic Valve Implantation (PS TAVI)

Aortic Valve Stenosis

Poland
Eli Lilly and Company

Completed

Comparison of Two Basal Insulins for Patients With Type 2 Diabetes on Anti-Hyperglycemic Medications (IOPE) (IOPE)

Diabetes Mellitus, Type 2

United States, Puerto Rico, Brazil, Canada
Centre Hospitalier Universitaire de Saint Etienne

Completed

Heparin Antagonization by Protamine in Cardiac Surgery: Pharmacokinetic/Pharmacodynamic Study (PICS)

Cardiac Surgery Requiring Extracorporeal Circulation

France
Eli Lilly and Company

Completed

Comparison of Two Basal Insulins for Patients With Type 2 Diabetes (IOOY) (IOOY)

Diabetes Mellitus Type 2

Korea, Republic of, Hungary, United States, Mexico, Argentina, India, Poland, Taiwan, Spain
The University of Texas Health Science Center,...

Completed

Detemir Versus NPH for Type 2 Diabetes Mellitus in Pregnancy (Determin)

Diabetes Mellitus, Type 2

United States
SANE-Society of Anesthesiology
Instituto de Cardiologia do Rio Grande do Sul; Fundação Universitária de Cardiologia...

Completed

Clinical Trial Comparing Heparin and Protamine Fixed and Titrated Doses in Cardiac Surgery With Cardiopulmonary Bypass

Cardiac Surgery | Cardiopulmonary Bypass | Anticoagulation

Brazil
University of Ioannina

Recruiting

Heparin Reversal With Two Different Protamine Ratios After Cardiopulmonary By-pass.

Coagulation Disorder | Cardiac Surgery | CAD | Valve Heart Disease

Greece
Assistance Publique - Hôpitaux de Paris
Action Research Group

Not yet recruiting

Antagonization of Heparin With Protamine Sulfate After TAVI (ATLANTIS-Prota)

Aortic Valve Stenosis | Heart Valve Diseases
Hongwen Ji

Completed

Prospective Trial of Autologous Platelet Rich Plasma in Aortic Surgery

C.Surgical Procedure; Cardiac

China
University of Texas Southwestern Medical Center
Novo Nordisk A/S

Terminated

Duration of The Honeymoon Phase of Type 1 Diabetes: A Comparison of Insulins Detemir, Glargine and NPH

Type 1 Diabetes

United States
St. Antonius Hospital
St. Antonius Research Fund

Recruiting

Routine Versus Selective Protamine Administration to Reduce Bleeding Complications After Transcatheter Aortic Valve Implantation (POPular ACE TAVI)

Aortic Valve Stenosis

Belgium, Netherlands
Fudan University
Novo Nordisk A/S

Unknown

Study on Liver Fat Content and Visceral Fat Mass in Overweight and Obese Type 2 Diabetes Patients After Treatment With Basal Insulin

Type 2 Diabetes Mellitus

China
Eli Lilly and Company

Completed

A Comparison Study of Basal Bolus Therapies Together With Lispro Insulin in Type 2 Diabetes Patients

Diabetes Mellitus, Type 2

Romania, Italy, Belgium, Poland, Greece, Germany, United Kingdom, Turkey, Czech Republic, Slovakia
Assiut University

Completed

Insulin in Treatment of Diabetes Mellitus With Pregnancy

Diabetes
The Medicines Company

Completed

Comparing Angiomax to Heparin With Protamine Reversal in Patients OPCAB (OPCAB)

Cardiac Surgery | Coronary Artery Bypass Surgery

United States
Eli Lilly and Company

Completed

Comparison of Two Basal Insulins for Patients With Type 2 Diabetes Taking Oral Diabetes Medicines and Exenatide

Diabetes Mellitus, Type 2

United States, Puerto Rico
Eli Lilly and Company

Completed

Effects of Insulin in Perceived Mood Symptoms in Patients With Type 2 Diabetes

Type 2 Diabetes

United States
Eli Lilly and Company

Completed

Comparison of Two Basal Insulin Therapies for Patients With Type 1 Diabetes (IOOZ)

Diabetes Mellitus, Type 1

Russian Federation, United States, Australia, Greece, Argentina, Hungary, Brazil, Mexico, Romania
Eli Lilly and Company
Alkermes, Inc.

Completed

A Study for Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Japan
University Hospital, Strasbourg, France

Unknown

Heparin Based on Ideal Body Weight for Cardiopulmonary Bypass in Obese Patients (HEPOIRINE)

Cardiac Surgery | Cardiopulmonary Bypass | Obese Patients (BMI ≥ 30 kg/m²)

France
Mannkind Corporation

Completed

Efficacy and Safety in Subjects With Type 2 Diabetes Receiving Subcutaneous Basal Insulin and Prandial Inhalation of Technosphere/Insulin Versus Subcutaneous Premixed Insulin Therapy Over a 52-Week Treatment Period and a 4-Week Follow-up

Diabetes Type 2

Brazil, Spain, United States, Argentina, Canada, Chile, Mexico, Poland, Russian Federation, United Kingdom
Elaine Chow
Sanofi

Completed

Toujeo Versus NPH Self-titration Study

Diabetes Mellitus, Type 2

Hong Kong
Dennis G. Karounos, M.D.
Novo Nordisk A/S

Completed

Veterans Inpatient Insulin Study and Transition to Outpatient Therapy (VIISTA)

Type 2 Diabetes Mellitus

United States
Sanofi

Completed

6-month Comparison of Morning Lantus Versus Neutral Protamine Hagedorn Insulin in Young Children With Type 1 Diabetes (PRESCHOOL)

Type 1 Diabetes Mellitus

United States, Austria, Brazil, Chile, Czech Republic, Germany, Hungary, India, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Turkey
Sanofi

Completed

Lantus Versus Humalog Mix as add-on Therapy in Type Diabetes Patients Failing Sulfonylurea and Metformin Combination Treatment

Diabetes Mellitus, Type 2

United States
Eli Lilly and Company

Completed

Comparison of the Efficacy and Safety of Two Insulin Intensification Strategies

Diabetes Mellitus, Type 2

Turkey, Argentina, Korea, Republic of, Brazil, China, Egypt, India, Spain
MurciaSalud

Completed

Efficacy of Calcifediol Supplementation in Asthma Control in Asthmatic Patients With Vitamin D Deficiency (ACViD) (ACViD)

Asthma, Bronchial

Spain
Steno Diabetes Center Copenhagen
Zealand University Hospital; Novo Nordisk A/S; Rigshospitalet, Denmark; Hvidovre... and other collaborators

Completed

The Copenhagen Insulin and Metformin Therapy Trial (CIMT)

Arteriosclerosis | Atherosclerosis | Type 2 Diabetes

Denmark
TCI Co., Ltd.

Recruiting

Assessment of Anti-aging Efficacy of Marine Collagen Peptides

Skin Condition | Nails, Ingrown | Hair Fragility

Taiwan
Wake Forest University Health Sciences

Terminated

The Efficacy of Crotaline Fab Antivenom for Copperhead Snake Envenomations

Snake Envenomation

United States
University Hospital Tuebingen

Unknown

Peptide-specific Vaccination in HLA-A*02 Positive Patients With Biochemical Recurrence After Radical Prostatectomy

Recurrent Prostate Cancer
Novo Nordisk A/S

Completed

A Non-interventional Study of Ability and Willingness to Pay for BIAsp 30 in a Real World Population With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2 | Diabetes

India
Sun Yat-sen University
Eli Lilly and Company; Ministry of Health, China; Amylin Pharmaceuticals, LLC.

Completed

Effect of Different Interventions on Glycemic Control and β-cell Function in Newly Diagnosed Type 2 Diabetic Patients

Diabetes Mellitus, Type 2 | Newly Diagnosed

China
Fate Therapeutics

Completed

Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Chronic Myelogenous Leukemia | Hematologic Malignancies | Acute Graft-versus-host Disease

United States
Vancouver General Hospital

Terminated

Insulin Therapy for Post-transplant Glucocorticoid Induced Hyperglycemia (PTHG)

Post-Transplant Glucocorticoid Induced Diabetes

Canada
Novo Nordisk A/S

Withdrawn

A Research Study, Looking at How NovoMix® Works in People With Type 2 Diabetes in Local Clinical Practice in Algeria (B Simple)

Diabetes Mellitus, Type 2

Algeria
Aga Khan University
London School of Hygiene and Tropical Medicine; Emory University; World Health... and other collaborators

Completed

Simplified Antibiotic Therapy for Sepsis in Young Infants (SATT)

Sepsis | Infection | Neonatal Sepsis

Pakistan
Abertawe Bro Morgannwg University NHS Trust
Novo Nordisk A/S

Unknown

Randomized Controlled Trial of Insulin Versus Tablets for Latent Autoimmune Diabetes in Adults (LADA) (LIT)

Latent Autoimmune Diabetes in Adults LADA

United Kingdom
Tehran University of Medical Sciences

Completed

Biphasic Insulin Aspart Versus NPH Plus Regular Human Insulin in Type 2 Diabetic Patients

Diabetes Type 2

Iran, Islamic Republic of
Novo Nordisk A/S

Completed

Comparison of Subject-driven Titration of Biphasic Insulin Aspart (BIAsp) 30 Twice Daily Versus Investigator-driven Titration of BIAsp 30 Twice Daily Both in Combination With Oral Antidiabetic Drugs in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

China
Novo Nordisk A/S

Completed

Observational Safety Study in Subjects With Type 2 Diabetes Mellitus Starting or Switching to Biphasic Insulin Aspart 30 Treatment

Diabetes Mellitus, Type 2 | Diabetes

Denmark
Novo Nordisk A/S

Completed

Observational Study of Biphasic Insulin Aspart 30 Alone or in Combination With Oral Hypoglycaemic Agents in Subjects With Type 2 Diabetes (PRESENT)

Diabetes Mellitus, Type 2 | Diabetes

Korea, Republic of
Novo Nordisk A/S

Completed

Comparison of Biphasic Insulin Aspart 30 Individually Adjusted by the Subject and the Trial Physician, Both Combined With Metformin in Subjects With Type 2 Diabetes (SimpleMix™)

Diabetes Mellitus, Type 2 | Diabetes

United Kingdom, Poland, Spain, India, Argentina, China
Novo Nordisk A/S

Completed

Observational Study of Safety of NovoMix® 30 Treatment for Type 2 Diabetes (Start)

Diabetes Mellitus, Type 2 | Diabetes

Sweden

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