Search clinical trials for: Pyronaridine Tetraphosphate

Total 45 results

Medicines for Malaria Venture
Richmond Pharmacology Limited; PharmaKinetic Ltd

Active, not recruiting

A Healthy Volunteer Safety Study of Pyronaridine Tetraphosphate Taken in Combination With Piperaquine Tetraphosphate

Healthy

United Kingdom
Armaceutica, Inc.
Ifakara Health Research and Development Centre; Uganda Cancer Institute; African... and other collaborators

Recruiting

Pyronaridine in Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL)

Senegal
Medicines for Malaria Venture
Shin Poong Pharmaceutical Co. Ltd.

Completed

Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy Volunteers

Malaria

Korea, Republic of
University Hospital Tuebingen
Sanaria Inc.; University of Oxford

Not yet recruiting

Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults

Malaria
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Unknown

Pyramax in Asymptomatic Carriers of P. Falciparum Monoinfections

Malaria,Falciparum

Gambia, Zambia
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)

Acute Malaria

Burkina Faso, Gabon, Mozambique, Uganda
Shin Poong Pharmaceutical Co. Ltd.

Completed

The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients (Phase3)

COVID-19

Korea, Republic of, Colombia, Argentina, Poland, Chile, United Kingdom
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; Bill and Melinda Gates Foundation and other collaborators

Completed

Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso (MALCOV)

Covid-19 | Malaria

Burkina Faso, Kenya
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Malaria Research and Training Center, Bamako...

Completed

Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmission (NECTAR1)

Malaria,Falciparum

Netherlands, Mali
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Completed

Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study

Anorexia | Body Dysmorphic Disorders

France
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

Malaria Infection

Kenya, Burkina Faso, Gambia, Zambia
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Human Mass Balance Study of Pyronaridine

Malaria

Switzerland
Shin Poong Pharmaceutical Co. Ltd.

Recruiting

The Safety and Efficacy of Pyronaridine-artesunate (Pyramax® or Artecom®)in COVID-19 Patients (PROVIDENCE)

Covid19

Philippines
University of Oxford

Completed

Pharmacokinetic Study of Primaquine and Pyronaridine-Artesunate in Healthy Subjects

Healthy

Thailand
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Bioequivalence of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet (SP-C-009-07)

Malaria

Switzerland
University of Oxford
NCHADS - Ministry of Health of Cambodia

Completed

Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malaria

Malaria, Falciparum

Cambodia
Shin Poong Pharmaceutical Co. Ltd.

Completed

The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients

COVID-19

Korea, Republic of
Centre de Recherche Médicale de Lambaréné
Institute of Tropical Medicine, University of Tuebingen

Not yet recruiting

A Crossover Bioavailability Clinical Trial of Parenteral Pyronaridine and Artesunate

Severe Malarial Treatment

Gabon
Medicines for Malaria Venture
Shin Poong Pharmaceutical Co. Ltd.

Completed

Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria

Plasmodium Falciparum Malaria

Cambodia, Gambia, Indonesia, Senegal, Thailand, Uganda
Shin Poong Pharmaceutical Co. Ltd.

Completed

Pilot Clinical Trial to Explore Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients

COVID-19

Korea, Republic of
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

Cohort Event Monitoring Study of Pyramax®

Malaria,Falciparum

Cameroon, Congo, The Democratic Republic of the, Congo, Côte D'Ivoire, Gabon
Medicines for Malaria Venture
Shin Poong Pharmaceuticals; Institute of Tropical Medicine, University of Tuebingen

Completed

Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria

Uncomplicated Plasmodium Falciparum Malaria

Gabon
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients

Malaria

Burkina Faso, Congo, The Democratic Republic of the, Kenya, Mali, Mozambique, Philippines, Côte D'Ivoire, Gabon
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients

Falciparum Malaria

Cambodia, India, Thailand, Burkina Faso, Côte D'Ivoire, Tanzania, Vietnam
Armed Forces Research Institute of Medical Sciences...
National Center for Parasitology, Entomology, and Malaria Control (CNM); Naval...

Recruiting

Drug Combinations of Atovaquone-Proguanil (AP) With ACT (APACT)

Plasmodium Falciparum Malaria (Drug Resistant)

Cambodia
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Terminated

Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria

Malaria

Korea, Republic of
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria

Malaria

Indonesia, Cambodia, India, Thailand
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine/Artesunate -Ritonavir Drug Drug Interaction Study

Malaria

Switzerland
Centre national de recherche et de formation sur...
Programme national de lutte contre le paludisme (PNLP), Burkina Faso; Unité... and other collaborators

Unknown

Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) (CHIMIO2)

Malaria | Burkina Faso

Burkina Faso
Royal Tropical Institute

Completed

Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria (PAAL)

Malaria

Kenya
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients

Malaria

Congo, The Democratic Republic of the, Gambia, Ghana, Indonesia, Kenya, Mali, Mozambique, Philippines, Senegal
Medicines for Malaria Venture
QIMR Berghofer Medical Research Institute; Children's Health Queensland Hospital... and other collaborators

Completed

Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria

Protozoan Infections | Malaria | Parasitemia | Malaria,Falciparum | Parasitic Disease | Malaria Recrudescence

Australia
Centre de Recherche Médicale de Lambaréné

Completed

Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection (SACT)

Schistosomiasis Haematobia

Gabon
University of Ibadan
Shin Poong Pharm Co Ltd 161 yoksam-ro, Gangnam-Gu Seoul 135-925, Korea; Institute...

Completed

Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine

Plasmodium Falciparum Malaria | Uncomplicated Malaria | Malaria Fever

Nigeria
sigma-tau i.f.r. S.p.A.

Completed

A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria

Malaria,Falciparum

Burkina Faso, Congo, The Democratic Republic of the, Gambia, Mozambique, Tanzania
GlaxoSmithKline
Medicines for Malaria Venture

Completed

A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate

Malaria, Vivax

United States
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

COVID-19 Treatment in South Africa

COVID-19

South Africa
Danish Headache Center

Completed

The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.

Headache | Dilatation of Cranial Arteries; MMA, STA and MCA

Denmark
Praxis Precision Medicines

Active, not recruiting

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

Epilepsy | SCN2A-DEE

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Samarium Sm 153 Lexidronam Pentasodium Combined With Zoledronic Acid or Pamidronate in Treating Patients With Relapsed or Refractory Multiple Myeloma and Bone Pain

Pain | Multiple Myeloma and Plasma Cell Neoplasm

United States
Papua New Guinea Institute of Medical Research
University of Melbourne; The University of Western Australia; Malaria in Pregnancy...

Unknown

A Safety, Tolerability, Pharmacokinetic and Efficacy Study of Azithromycin Plus Piperaquine as Presumptive Treatment in Pregnant PNG Women

Pregnancy | Clinical Efficacy | Drug Kinetics | Infections, Plasmodia

Papua New Guinea
Praxis Precision Medicines

Recruiting

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE) (EMBOLD)

SCN2A Encephalopathy | SCN8A Encephalopathy

United States, Spain
Bruce Pollock
National Institute of Mental Health (NIMH)

Completed

Serotonergic Pharmacotherapy for Agitation of Dementia (SPAD)

Dementia | Alzheimer Disease | Dementia, Vascular

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Olanzapine With or Without Fosaprepitant Dimeglumine in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients Receiving Highly Emetogenic Chemotherapy

Malignant Neoplasm

United States, Guam

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