Search clinical trials for: Pyrotinib Maleate plus Letrozole

Total 89 results

Hunan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Pyrotinib in Combination With Letrozole in Patients With HER2-Positive, ER-Positive Metastatic Breast Cancer

Metastatic Breast Cancer

China
xuexin he

Not yet recruiting

Adjuvant Dual Anti-HER2 Therapy in Patients With Small, Node-negative, HER2-positive Breast Cancer (SHERO)

HER2-positive Breast Cancer
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial of Loperamide Pharmacokinetics Effect on Pyrotinib Maleate

Healthy Participants

China
The First Affiliated Hospital with Nanjing Medical...
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Pyrotinib in Women With High-risk in Early Stage Breast Cancer

HER2-positive Breast Cancer

China
Shengjing Hospital

Active, not recruiting

Pyrotinib Maleate, CDK4/6 Inhibitor and Letrozole in Combination for Stage II-III TPBC: a Phase II Trial

Breast Cancer

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Effect of Low-fat Diet on the Pharmacokinetics of Pyrotinib in Healthy Participants

Healthy Participants
Fujian Medical University

Not yet recruiting

A Study to Evaluate Inetetamab + Pyrotinib + Chemotherapy in Previously Untreated HER2-Positive Metastatic Breast Cancer

HER2-positive Recurrent/Metastatic Breast Cancer
Shengjing Hospital

Recruiting

Pyrotinib Maleate, Trastuzumab, SHR6390 and Letrozole in Combination for Stage II-III TPBC

Breast Cancer

China
Beijing Chest Hospital
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

HER2 Mutant Non-small Cell Lung Cancer
Zhongshan Hospital Xiamen University

Not yet recruiting

An Exploratory Basket Study of Pyrotinib Maleate Tablets in HER2 Mutated or Amplified of Metastatic Solid Tumors

Solid Tumor
The First Affiliated Hospital of Zhengzhou University
BeiGene; Jiangsu Hengrui Pharmaceutical Co., Ltd.; RemeGen Co., Ltd.

Not yet recruiting

Study of Tislelizumab Combined With DisitamabVedotin and Pyrotinib Maleate in HER2-positive or Mutated Advanced Colorectal Cancer Who Failed Standard Therapy

HER2-positive or Mutated Advanced Colorectal Cancer
Wuhan University

Not yet recruiting

Exploratory Study of Neoadjuvant Treatment of HER2-positive Breast Cancer With Py in Combination With HP

Breast Cancer
Zhongshan People's Hospital, Guangdong, China

Recruiting

Anrotinib and Tirelizumab in First-line Treatment of RM-NPC

Nasopharyngeal Carcinoma

China
Sun Yat-sen University

Recruiting

Pyrotinib Plus Vinorelbine in Participants With HER2-positive Previously Treated Locally Advanced or Metastatic Breast Cancer

Breast Cancer | Breast Diseases | HER2-positive Breast Cancer | Vinorelbine | Pyrotinib

China
Fudan University

Completed

Pyrotinib Plus Trastuzumab Versus Pertuzumab Plus Trastuzumab

Breast Cancer

China
Henan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Treatment of Dalpiciclib Combined With Pyrotinib for Trastuzumab-sensitive HER2+ Advanced Breast Cancer(DAP-Her-02)

Breast Neoplasms

China
Zhejiang Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Pyrotinib Combined With Docetaxel in the First-line Treatment of HER2-positive MBC

Metastatic Breast Cancer

China
Tianjin Medical University Cancer Institute and...

Completed

Pyrotinib Maleate Combined With Vinorelbine in the Treatment of HER2-positive Advanced Breast Cancer

HER2-positive Advanced Breast Cancer

China
Fudan University

Recruiting

Pyrotinib Rechallenge in Her2-positive Metastatic Breast Cancer Pretreated With Pyrotinib and Trastuzumab

Metastatic Breast Cancer | HER2-positive Breast Cancer

China
Shandong Cancer Hospital and Institute

Unknown

Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain Metastasis

Breast Cancer | HER2-positive Breast Cancer

China
Henan Cancer Hospital

Active, not recruiting

A Study of Pyrotinib Plus Capecitabine in Patients With Brain Metastases From HER2-positive Metastatic Breast Cancer

HER2 Positive Metastatic Breast Cancer

China
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Pyrotinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer. (PHOEBE)

HER2 Positive Metastatic Breast Cancer

China
Xi'an International Medical Center Hospital

Not yet recruiting

Efficacy and Safety of Disitamab Vedotin Plus Pyrotinib or Naratinib in HER2-positive Breast Cancer Patients With Brain Metastasis

Breast Cancer

China
Hebei Medical University Fourth Hospital

Unknown

Pyrotinib in Combination With Nab-paclitaxel in Patients With HER2-positive Advanced Breast Cancer: an Exploratory Study

HER2-positive Breast Cancer
Fudan University

Active, not recruiting

Pyrotinib Combined With Brain Radiotherapy in Breast Cancer Patients With Brain Metastases

Breast Cancer | HER2-positive Breast Cancer | Brain Metastases

China
Yantai Yuhuangding Hospital
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Recruiting

Pyrotinib Combined With Trastuzumab,Dalpiciclib and Letrozole for HR+/HER2+ Breast Cancer

Breast Cancer

China
Caigang Liu
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Study of ARX788 Combined With Pyrotinib Maleate Versus TCBHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) as Neoadjuvant Treatment in HER2-positive Breast Cancer Patients

HER2-positive Breast Cancer

China
Guangdong Association of Clinical Trials
Chinese Thoracic Oncology Group

Recruiting

Phase II Umbrella Study Directed by Next Generation Sequencing (TRUMP)

Carcinoma, Non-Small-Cell Lung

China
Cancer Institute and Hospital, Chinese Academy...

Unknown

A Study of Pyrotinib Plus Vinorelbine in Patients With Brain Metastases From HER2-positive Metastatic Breast Cancer (Pyrotinib)

Breast Cancer | Brain Metastases

China
Assiut University

Recruiting

Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome

Infertility, Female

Egypt
Assiut University

Unknown

Letrozole in Assisted Reproductive Technology

to Evaluate Letrozole as a Modality for Minimal Ovarian Stimulation in ICSI Cycles .

Egypt
Second Affiliated Hospital of Soochow University

Recruiting

A Clinical Study of Darcilil Combined With AI Combined With Pyrrotinib in the Treatment of TPBC

Breast Neoplasms

China
Zagazig University

Completed

Study to Compare Between Combimed Metformin-letrozole and Ovarian Drilling in Pcos With Bilateral Ovarian Drilling in Clomiphene-resistant Infertile Women With Polycystic Ovarian Syndrome

Focus of Study

Egypt
Peking Union Medical College Hospital

Not yet recruiting

Pyrotinib Combined With Trastuzumab and AI in the First-line Treatment of HER2 Positive/ HR Positive MBC (Pyrotinib)

Breast Diseases | Metastatic Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast | Breast Cancer Female | Hormone Receptor Positive Tumor
Fengzhi Feng

Recruiting

Dalpiciclib Combined With Letrozole in HR+/HER2 - Gynecologic Solid Tumors

Recurrent Ovarian Carcinoma

China
Fuzhou General Hospital

Not yet recruiting

Pyrotinib Combined With Trastuzumab Plus Aromatase Inhibitor in Treatment of Breast Cancer

Breast Diseases | Metastatic Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast | Breast Cancer Female | Hormone Receptor Positive Tumor

China
Borstkanker Onderzoek Groep
Novartis; Philips Healthcare

Active, not recruiting

Tailoring NEOadjuvant Therapy in Hormone Receptor Positive, HER2 Negative, Luminal Breast Cancer. (NEOLBC)

Breast Neoplasms

Netherlands
Cancer Institute and Hospital, Chinese Academy...

Unknown

Pyrotinib Plus Fulvestrant in Patients With HR+/HER2+ Metastatic Breast Cancer (Pyrotinib+Fulvestrant ) (Pyrotinib)

Breast Cancer | HER2-positive Breast Cancer

China
Jinming Yu
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Phase Ⅱ Trial of Pyrotinib Combination With CDK4/6 Inhibitor SHR6390 in Patients Prior Trastuzumab-treated Advanced HER2-Positive Breast Cancer (INPHASE)

Metastatic Breast Cancer | HER2-positive Breast Cancer

China
The Affiliated Hospital of Qingdao University
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Neoadjuvant Dalpiciclib Plus Letrozole for HR+/HER2- Breast Cancer

Breast Cancer
Novartis Pharmaceuticals
Roche - Prof. Dr. Jens Huober et al.

Terminated

Study of the Efficacy and Safety of Letrozole Combined With Trastuzumab in Patients With Metastatic Breast Cancer (eLEcTRA)

Metastatic Breast Cancer

Germany
Henan Cancer Hospital

Unknown

Neoadjuvant Study of Pyrotinib and Trastuzumab Plus Vinorelbine in Trastuzumab-refractory HER2-Positive Breast Cancer.

HER2 Positive Breast Cancer
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Phase II Clinical Study of T-DM1 and Pyrotinib Maleate in Patients With HER2-positive Metastatic Breast Cancer Who Had Progressed on TKI Therapy

HER2+ Advanced Breast Cancer Patients Progressing on TKI Therapy
Shengjing Hospital

Recruiting

Efficacy and Safety of Pyrotinib Maleate Combined With ARX788 Neoadjuvant Treatment in Breast Cancer Patients

Breast Neoplasms

China
Henan Cancer Hospital

Completed

Neoadjuvant Study of Pyrotinib and Trastuzumab Plus Docetaxel and Carboplatin in HER2 Positive Breast Cancer Patients.

HER2 Positive Breast Cancer

China
Pfizer

Completed

Study to Evaluate Overall Survival in Japanese Patients With HR+/HER2- Advanced Breast Cancer Treated With Palbociclib Plus Letrozole

Breast Cancer

Japan
Fudan University

Recruiting

Pyrotinib Combined With Pemetrexed Plus Carboplatin in the First-line Treatment

Lung Cancer, Non-small Cell

China
West China Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Pyrotinib Maleate Tablets Combined With Albumin Paclitaxel and Trastuzumab for Her2-positive Breast Cancer

Breast Cancer | HER2 Positive | Combination Chemotherapy

China
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Novartis Pharmaceuticals; University of California,... and other collaborators

Completed

Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC)

Fibrolamellar Carcinoma | Fibrolamellar Liver Cancer

United States
Cairo University

Completed

Ovulation Induction in Clomiphene Citrate Resistant PCO Women

Polycystic Ovary Syndrome | Infertility

Egypt

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