Search clinical trials for: Recombinant human luteinizing hormone (r-hLH)

Total 339 results

Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Terminated

Study to Evaluate if the Addition of r-hLH (Luveris®) to FSH From Day 8 of Ovarian Stimulation is Able to Decrease Total FSH Dose and to Improve Cycle Outcome in Infertile Women Undergoing ART, Who Required High FSH Dose in a Previous Cycle (Luveris in ART)

Reproductive Techniques, Assisted

Italy
Merck KGaA, Darmstadt, Germany
Merck Pte. Ltd., Singapore

Completed

A Study Using Recombinant Human Luteinizing Hormone (r-hLH, Luveris®) in the Treatment of Chinese Women With Hypogonadotropic Hypogonadism

Hypogonadism

China
Merck KGaA, Darmstadt, Germany

Completed

A Randomised, Phase II, Comparative Study With a Parallel Control for Evaluating the Efficacy and Safety of Combined Treatment of Lutropin Alpha and Recombinant Human Luteinizing Hormone in the Middle of the Controlled Ovarian Stimulation Follicular Phase in Women With Reduced Ovarian Reserve

Infertility | Ovulation Induction

Spain
Regionshospitalet Viborg, Skive

Completed

Study to Examine Effect of Recombinant Luteinizing Hormone (r-Lh) and Recombinant Human Chorionic Gonadotropin (r-hCG) for Ovarian Stimulation in Assisted Reproduction Techniques (ART)

Infertility | Controlled Ovarian Stimulation

Denmark
EMD Serono

Terminated

Luveris® (Lutropin Alfa for Injection) in Women With Hypogonadotropic Hypogonadism (Luteinizing Hormone [LH] Less Than [<] 1.2 International Unit Per Liter [IU/L])

Hypogonadotropic Hypogonadism

United States
Merck KGaA, Darmstadt, Germany
Merck Serono Co., Ltd., China

Completed

Predictive Markers in Chinese Growth Hormone Deficiency (GHD) Children Treated With Saizen®

Dwarfism, Pituitary
Merck KGaA, Darmstadt, Germany
Merck Serono S.P.A., Italy

Terminated

A Trial to Evaluate the Correlation Between Spontaneous Catch-up Growth, Clinical Response to Saizen (Recombinant Human Growth Hormone, r-hGH) and Gene Expression Profiling in Children Small for Gestational Age (SGA) (SAIZEN in SGA)

Infant, Small for Gestational Age

Italy
EMD Serono

Completed

Growth Hormone in the Treatment of HIV-Associated Wasting

HIV Infections | HIV Wasting Syndrome
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Terminated

A Clinical Trial to Determine the Effect of Lutropin Alfa on Embryo Quality and Implantation Rate in Advanced Reproductive Age

Infertility | Ovulation Induction

Spain
EMD Serono

Completed

An Efficacy and Safety Trial of Serostim® in the Maintenance of the Treatment Effect Obtained During the Study of Serostim® in Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome

Human Immunodeficiency Virus Infections | Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS)
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

Efficacy and Safety Evaluation of Recombinant Human Growth Hormone (r-hGH), Saizen®, on a Population of Children With Hypochondroplasia, Treated at Least 3 Years or Until Near Final Height, When Applicable, in Comparison With a Historic Cohort of Non-treated Children

Hypochondroplasia

France
EMD Serono

Completed

Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Deficiency

Pituitary Dwarfism | Childhood-onset Growth Hormone Deficiency

United States
EMD Serono

Completed

Safety and Efficacy Trial of Serostim® in the Treatment of Subjects With Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS)

Human Immunodeficiency Virus Infections | Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS)
EMD Serono

Completed

A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive Technologies

Infertility | Ovarian Stimulation
EMD Serono

Completed

Safety and Efficacy Study of Serostim® Human Immunodeficiency Virus-Associated Adipose Redistribution Syndrome

Human Immunodeficiency Virus-Associated Adipose Redistribution Syndrome

United States, Canada
Reproductive Medicine Associates of New Jersey

Completed

Use of r-hLH (Luveris) in Donors Previously Treated With r-hFSH (Gonal F)

Outcome During r-hFSH Stimulation | Outcome During r-hFSH and r-hLH Stimulation

United States
EMD Serono

Completed

Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients

HIV Infections | Lipodystrophy

United States, Canada
University of Pennsylvania
Baylor Health Care System

Completed

Recombinant Human Growth Hormone During Rehabilitation From Traumatic Brain Injury. (Growth-TBI)

Traumatic Brain Injury

United States
Peking University People's Hospital
Peking University First Hospital; The Second Hospital of Hebei Medical University and other collaborators

Unknown

The Effectiveness and Safety of the Prolonged Down-regulation Protocol for Controlled Ovarian Hyperstimulation

Infertility, Female
Merck KGaA, Darmstadt, Germany

Completed

Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART) (ESPART)

Infertility

Germany
Merck KGaA, Darmstadt, Germany
Merck, S.L., Spain

Terminated

A Phase II Study to Assess the Efficacy and Safety of Luveris® (Lutropin Alfa) in Mid Follicular Phase for Controlled Ovarian Stimulation (COS) in Advanced Reproductive Age

Infertility | Ovulation Induction

Spain
Merck KGaA, Darmstadt, Germany

Completed

Safety and Efficacy of Pre-defined, Fixed Dose of Gonal-f Pen Based on Subject Baseline Characteristics in Subjects Undergoing in Vitro Fertilization (IVF) (CONSORT)

Infertility

France
Merck KGaA, Darmstadt, Germany

Completed

An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)

Adult Growth Hormone Deficiency

United Kingdom, Germany, Australia, Sweden
The University of Texas Medical Branch, Galveston
The Moody Foundation

Completed

Anterior Pituitary Hormone Replacement in Traumatic Brain Injury

Traumatic Brain Injury | Growth Hormone Deficiency

United States
Instituto Valenciano de Infertilidad, IVI VALENCIA

Completed

Luteinizing Hormone (LH) Supplementation in Gonadotropin-releasing Hormone (GnRH) Antagonist Cycles

Ovarian Stimulation

Spain
Merck KGaA, Darmstadt, Germany
Merck Serono S.A.S, France

Completed

Analysis of Two Therapeutic With Cetrotide® in Polycystic Ovarian (PCO) Women in Assisted Reproductive Technology (ART) (ATTAC-PCO)

Polycystic Ovarian Syndrome

France
University of Miami
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Effects of Leptin Replacement in Children

Obesity | Diabetes | Metabolic Syndrome

United States
University of Miami
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Effects of Human Leptin Replacement

Obesity | Diabetes | Metabolic Syndrome

United States
Columbia University
Tercica

Terminated

Differential Effects of rhGH vs. rhIGF-1 on Cardiovascular Risk Factors

Growth Hormone Deficiency

United States
Royan Institute

Unknown

Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism

Infertility

Iran, Islamic Republic of
Ache Laboratorios Farmaceuticos S.A.

Unknown

Non-inferiority Evaluation of Pain Intensity After Biomatrop (Somatropin) Application in Relation to Hormotrop (Somatropin), in Healthy Subjects

Healthy Subjects

Brazil
Rigshospitalet, Denmark
Odense University Hospital; Karolinska University Hospital; Hvidovre University... and other collaborators

Completed

Nordic Luveris Study

Infertility | In Vitro Fertilization

Denmark
Merck KGaA, Darmstadt, Germany

Completed

r-hLIF for Improving Embryo Implantation in IVF

Infertility Implantation Failure
Merck KGaA, Darmstadt, Germany

Completed

A Multicentre, Randomised, Double-blind, Placebo-controlled Proof of Concept Study to Compare the Efficacy and Safety of r-hLIF (Emfilermin) for Improving Embryo Implantation Following in Vitro Fertilization (IVF) and Embryo Transfer (ET) in Women With Recurrent Implantation Failure

Infertility Implantation Failure
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Stem Cell Factor Medication for Aplastic Anemia

Pancytopenia | Aplastic Anemia

United States
Merck KGaA, Darmstadt, Germany

Completed

GONAL-f CONSORT (Consistency in r-hFSH Starting Doses for Individualised Treatment)

Infertility

Germany
Merck KGaA, Darmstadt, Germany

Completed

CONSORT Randomized Controlled Trial in Assisted Reproductive Technology

Infertility

Switzerland
Merck KGaA, Darmstadt, Germany

Completed

A Study to Evaluate the Ease of Use, Local Tolerance, Safety and Effectiveness of Gonal-f® (Filled-by-mass in a Prefilled Pen)

Infertility

Greece
EMD Serono

Completed

A Study to Compare the Safety and Efficacy of Cetrotide® 3 Milligram (mg) Versus Antagon™ in Women Undergoing Ovarian Stimulation

Infertile Women Undergoing Assisted Reproductive Technology (ART)
Cinnagen

Completed

Comparing Efficacy and Safety of CinnaGen Biosimilar Growth Hormone (CinnaTropin®) Versus Nordilet in Children With Idiopathic Growth Hormone Deficiency

Idiopathic Growth Hormone Deficiency
Massachusetts General Hospital
Genentech, Inc.

Completed

Effect of Growth Hormone on Bone Metabolism in Anorexia Nervosa

Anorexia Nervosa | Osteoporosis | Osteopenia | Eating Disorders

United States
Medical University of Vienna

Suspended

Efficacy of Ovarian Stimulation Based on FSHR Genotype Status

Sterility

Austria
NHS Greater Glasgow and Clyde

Completed

Efficacy and Safety of R-hLH (Luveris ®) Priming Prior to R-HFSH Treatment in Infertile Women Undergoing IVF-ET

Infertility

Denmark, France, United Kingdom
Shandong University
China Medical University, China; The Affiliated Hospital of the Chinese Academy... and other collaborators

Withdrawn

Recombinant Human Thrombopoietin (rhTPO) Combining Rituximab Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP)

Purpura | Idiopathic Thrombocytopenic Purpura

China
Tissa Hata, MD

Completed

Effects of Subcutaneous Hyaluronidase Administration on Psoriatic Plaques

Psoriasis

United States
NRG Oncology
National Cancer Institute (NCI)

Suspended

Niraparib With Standard Combination Radiation Therapy and Androgen Deprivation Therapy in Treating Patients With High Risk Prostate Cancer (NADIR)

Prostate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8

Canada, United States
University of Maryland, Baltimore
Children's Hospital of Philadelphia

Withdrawn

Growth Hormone for Osteoporosis Pseudoglioma Syndrome (GHOPPG)

Osteoporosis Pseudoglioma Syndrome

United States
University Hospital Tuebingen

Completed

D3-GHR Polymorphism and Turner Syndrome

Turner Syndrome | Short Stature

Germany
Weill Medical College of Cornell University
Genentech, Inc.

Terminated

Effect of Growth Hormone on Leptin, Cytokines and Body Composition of Children With Growth Failure Due to Chronic Kidney Disease

Chronic Kidney Disease

United States
GeneScience Pharmaceuticals Co., Ltd.
Tongji Hospital; Shengjing Hospital; Shandong Provincial Hospital; Children's Hospital... and other collaborators

Recruiting

A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Children With Achondroplasia

Achondroplasia

China

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