Search clinical trials for: rhIGF-1/rhIGFBP-3

Total 2122 results

Insmed Incorporated

Terminated

Research Study Using Recombinant Human Insulin-Like Growth Factor-1/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 for Children With Noonan Syndrome

Noonan Syndrome

United States
Insmed Incorporated

Completed

IGF-I/IGFBP-3 Therapy in Children and Adolescents With Growth Hormone Insenitivity Syndrome (GHIS) Such as Laron Syndrome

Laron Syndrome | Growth Hormone Insensitivity Syndrome (GHIS)

United States, Argentina, Australia, Brazil, China, Egypt, Germany, Israel, Italy, Norway, Peru, Slovakia, Turkey, United Kingdom
Insmed Incorporated
Muscular Dystrophy Association

Completed

Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1

Myotonic Dystrophy Type 1

United States
Shire

Completed

Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP) (PEDAL)

Retinopathy of Prematurity (ROP)

United States, Italy, Netherlands, Poland, Sweden, United Kingdom
Shire

Completed

IGF-1/IGFBP3 Prevention of Retinopathy of Prematurity

Retinopathy of Prematurity (ROP)

United States, Italy, Netherlands, United Kingdom, Sweden, Poland
Boston Children's Hospital
Autism Speaks; International Rett Syndrome Foundation

Completed

Treatment of Rett Syndrome With rhIGF-1 (Mecasermin [rDNA]Injection)

Rett Syndrome

United States
Children's Hospital Medical Center, Cincinnati

Completed

IGF-1 Treatment for Individuals With Short Stature Due to PAPP-A2 Deficiency

Short Stature
Ipsen

Completed

Prepubertal Children With Growth Failure Associated With Primary Insulin-Like Growth Factor-1 (IGF-1) Deficiency

Growth Disorders | Insulin-Like Growth Factor-1 Deficiency

United States
Massachusetts General Hospital
Tercica

Completed

Safety Profile of Insulin Like Growth Factor-1 (IGF-I) Administration in Adolescents

Anorexia Nervosa

United States
National Institute of Neurological Disorders and...

Completed

A 48-Week (24-Week Baseline Followed by a 24-Week Treatment) Phase II Pilot Study of the Tolerability and Effect/Efficacy of Subcutaneously Administered Insulin-Like Growth Factor-1 (rhIGF) (CEP-151) in Multiple Sclerosis (MS) Patients

Multiple Sclerosis

United States
University College Cork

Completed

Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack (RESUS-AMI)

Myocardial Infarction | Heart Failure

Ireland, Netherlands
Ipsen

Completed

Recombinant Human Insulin-Like Growth Factor (rhIGF-1) Treatment of Short Stature Associated With IGF-1 Deficiency

Growth Disorders | Insulin-Like Growth Factor-1 Deficiency

United States
Nationwide Children's Hospital
Tercica

Terminated

Effect of Increlex® on Children With Crohn Disease

Crohn Disease

United States
University of Jordan

Completed

Growth Hormone (GH) Deficiency & Insulin Like Growth Factor 1 (IGF-I)/ Insulin Like Growth Factor Binding Protein 3 (IGFBP-3) Ratio

Diagnosis of GHD With IGF-I/IGFBP-3 Ratio
Royal Surrey County Hospital NHS Foundation Trust

Completed

Acute Kidney Injury - Biomarkers in Major Abdominal Surgery (AKI-BioMAS)

Acute Kidney Injury

United Kingdom
Dompé Farmaceutici S.p.A

Recruiting

A Study to Evaluate Safety and Efficacy of a New Formulation of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution in Patients With Dry Eye Disease (REDUCO)

Dry Eye Disease

United States, Italy
Massachusetts General Hospital

Completed

Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa (814)

Disorder of Bone Density and Structure, Unspecified

United States
Ipsen

Terminated

rhGH and rhIGF-1 Combination Therapy in Children With Short Stature Associated With IGF-1 Deficiency

Insulin-like Growth Factor-1 Deficiency

United States
Boston Children's Hospital
International Rett Syndrome Foundation

Completed

Treatment of Rett Syndrome With Recombinant Human IGF-1

Rett Syndrome

United States
Massachusetts General Hospital

Completed

IGF-1 and Bone Loss in Women With Anorexia Nervosa

Anorexia Nervosa | Osteoporosis | Osteopenia

United States
Dompé Farmaceutici S.p.A
Covance

Completed

Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers (NGF0112)

Healthy

Switzerland, United Kingdom
University of Massachusetts, Worcester

Completed

The IGFBP-3 Stimulation Test: A New Tool for the Diagnosis of Growth Hormone Deficiency in Children.

Growth Hormone Deficiency | Short Stature

United States
University of Copenhagen
Nordea-fonden

Completed

The Effects of Sea Buckthorn and Strawberry on Postprandial Glycaemia, Insulinemia and Appetite (OPUS-WP3C)

Glucose Intolerance | Insulin Sensitivity

Denmark
University of Thessaly

Completed

Recovery Kinetics After Speed-Εndurance Maintenance Training

Muscle Damage

Greece
Dompé Farmaceutici S.p.A
Cross Research S.A.

Completed

Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye

Dry Eye Syndrome

Austria
Insud Pharma

Completed

Bioavailability and Safety of Two Oral Fixed Dose Preparations Containing 18 mg Ivermectin (IVM 18 MG TABLETS, LICONSA S.A., Spain) Versus Reference Dosing (Weight Based) Containing 6 mg Ivermectin (REVECTINA®, Abbott Laboratórios do Brasil Ltda, Brazil)

Helminthiasis
Hospices Civils de Lyon

Completed

Impact of Milk Polar Lipids on Lipids Digestion, Absorption and Metabolism (VALOBAB-D)

Cardiometabolic Risk

France
Hanmi Pharmaceutical Company Limited

Not yet recruiting

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HCP1904 in Healthy Male Volunteers.

Healthy

Korea, Republic of
Seoul National University Hospital

Unknown

Verify the Effectiveness rTMS Using MEG (rTMS)

Tinnitus

Korea, Republic of
University of Zurich

Recruiting

Subjective and Objective Outcome of ESS in CRSwNP

CRS

Switzerland
Massachusetts General Hospital

Completed

Effects of Anorexia Nervosa on Peak Bone Mass

Anorexia Nervosa

United States
Ziqiang Li

Active, not recruiting

Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation

Complete and Accurate Statistical Data of 60 Patients | CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately | Postoperative Tacrolimus Concentrations Were Accurately Recorded in 60 Patients | According to the Diagnosis and Grading Criteria of Acute Kidney Injury, the... and other conditions

China
JW Pharmaceutical

Completed

To Evaluate the Safety and Pharmacokinetic Interactions in Healthy Volunteers

Healthy

Korea, Republic of
Hanmi Pharmaceutical Company Limited

Completed

A Study to Evaluate the PK, Safety and Tolerability of HCP1803.

Healthy

Korea, Republic of
Federal University of Paraíba

Completed

The Effects of High Intensity Interval Exercise in Obese

Obesity | Endothelial Dysfunction
University of Alberta

Completed

Chest Compression and Sustained Inflation

Newborn Infants Having Asystole or Bradycardia at Birth

Canada
Shenzhen TargetRx, Inc.
First Affiliated Hospital Bengbu Medical College

Completed

TGRX-326 Phase I/II Pharmacokinetic Study

Non Small Cell Lung Cancer

China
Pfizer

Completed

A Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Obesity

Obesity

United States, Taiwan, Canada, Japan
University of Sao Paulo General Hospital

Completed

Comparison of Two Application Regimens for Viscosupplementation

Osteoarthritis

Brazil
AstraZeneca

Active, not recruiting

Study of AZD3152 Intramuscular Injection or Intravenous Infusion in Healthy Japanese Adult Participants

COVID-19, SARS-CoV-2

Japan
Yale University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Effects of Novel E-cigarette Constituents on Adults TCORS 3.0

Nicotine Use Disorder
Centre Hospitalier Universitaire Dijon

Recruiting

Analysis of Motor Skills in Subjects Aged 55 and Over: the Role of Cognitive Abilities for Planning Movement. (Vieillissement)

Mild Cognitive Disorder

France
Piquilloud Imboden Lise

Recruiting

Effect of Three Modalities of Spontaneous Breathing Tests on Respiratory Efforts in Tracheostomized Patients (TWEEP)

Mechanical Ventilation Complication

Switzerland
Sientra, Inc.

Active, not recruiting

AuraClens™ System in Processing of Lipoaspirate for Autologous Fat Grafting to the Breast (AuraGen)

Breast Fat Grafting Retention

United States
University of Arizona

Unknown

Efficacy of a Novel Sleep Intervention in Short Sleepers

Sleep

United States
Weill Medical College of Cornell University

Terminated

Incorporation of Genetic Expression of Airway Epithelium With CT Screening for Lung Cancer

Chronic Obstructive Pulmonary Disease | COPD

United States
Ospedale San Donato

Completed

Washcloths Effectiveness in Preventing Pressure Ulcers (Bathing)

Skin Ulcer | Pressure Ulcer

Italy
Spaarne Gasthuis
Maasstad Hospital; Amsterdam UMC

Not yet recruiting

Three Weeks of Cast Immobilisation Versus One Week of Brace Immobilisation in Distal Radius Fractures (DRPIPIII)

Fractures, Bone | Distal Radius Fractures

Netherlands
Tata Medical Center
Sanjay Gandhi Postgraduate Institute of Medical Sciences; Christian Medical...

Recruiting

One Week Versus Three Week in Adjuvant Radiotherapy in Breast Cancer (HYPORTAdjuvant)

Breast Cancer Female

India
Abbott Nutrition
National Health Service, United Kingdom; Changing Health

Active, not recruiting

Digitally-Enabled Weight Management Program on T2DM

Type 2 Diabetes | Weight Change, Body

United Kingdom

Search clinical trials for: rhIGF-1/rhIGFBP-3

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