Search clinical trials for: Rocuronium bromide (Org 9426)

Total 99 results

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Merck Sharp & Dohme LLC

Completed

A Study to Compare Different Intubating Doses of Zemuron in Pediatric and Adolescent Subjects Under General Anesthesia

Anesthesia
Merck Sharp & Dohme LLC

Completed

Comparative Study of Rocuronium With Vecuronium (Study 71101)(COMPLETED)

Anesthesia
Pontificia Universidad Catolica de Chile

Completed

Pharmacokinetic and Pharmacodynamic of Rocuronium

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Study of Efficacy, Pharmacokinetics, and Safety of Bolus Maintenance Doses of Org 9426 (Study P05976)(COMPLETED)

Muscle Relaxation
Merck Sharp & Dohme LLC

Completed

A Study to Determine the Dose Requirements of Rocuronium Bromide (Zemuron®) in Pediatric and Adolescent Subjects (21048)(COMPLETED)(P05797)

Anesthesia
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Org 25969 Administered After Zemuron® (MK-8616-042)

Neuromuscular Blockade
Merck Sharp & Dohme LLC

Completed

Efficacy, Safety and Pharmacokinetics of Sugammadex (Org 25969; MK-8616) at 3 Different Time Points After 0.6 mg/kg Esmeron® in Male Participants (P05940; MK-8616-020).

Neuromuscular Blockade
Sheba Medical Center

Unknown

Neuromuscular Blockade and Surgical Conditions (Sugamadex)

Morbid Obesity

Israel
Seoul National University Hospital

Recruiting

Acute Pharmacokinetic-pharmacodynamic Change of Rocuronium After Reperfusion of Renal Graft

End Stage Renal Disease | Transplantation

Korea, Republic of
Seoul National University Hospital

Unknown

Continuous Infusion Versus Intermittent Bolus Injection of Rocuronium (RCVB)

Anesthesia | Muscle Relaxation

Korea, Republic of
Radboud University Medical Center
Merck Sharp & Dohme LLC

Recruiting

Impact of Deep Neuromuscular Blockade During Total Hip Replacement Surgery on Postoperative Recovery and Immune Function (HIPPO)

Quality of Life | Postoperative Complications | Neuromuscular Blockade | Innate Inflammatory Response

Netherlands
Baudax Bio

Completed

Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing Surgery

Surgery | Anesthesia | Neuromuscular Blockade

United States
Amsterdam UMC, location VUmc

Unknown

Partial Neuromuscular Blockade for Lung Protective Mechanical Ventilation

Respiratory Insufficiency

Netherlands
Merck Sharp & Dohme LLC

Completed

Dose-Finding Trial With Sugammadex Administered at 3 and 15 Minutes After 1.0 and 1.2 mg/kg Rocuronium Bromide in Participants of ASA Class 1-3 (P05944; MK-8616-024)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982)

Gallbladder Disease

Germany, Italy
Merck Sharp & Dohme LLC

Completed

Dialysis of Sugammadex in Participants With Severe Renal Impairment (Study 19.4.333) (P05773)

Neuromuscular Blockade
Medtronic - MITG

Completed

The Effect of Neuromuscular Blockade on the Composite Variability Index (CVI) During Laryngoscopy

Anesthesia | Neuromuscular Blockade

United States
Wahba bakhet
Elite medical center

Completed

Deep vs Moderate Neuromuscular Blockade in Day Case Laparoscopic Cholecystectomy.

Muscle Relaxation

Egypt
Thomas Schricker
Merck Sharp & Dohme LLC

Terminated

Surgical Conditions During Vocal Cord Surgery Requiring Jet Ventilation With Moderate vs. Deep Neuromuscular Block

High-Frequency Jet Ventilation | Vocal Cord Resection

Canada
Wahba bakhet
Elite medical center

Completed

Deep NMB in Ambulatory Gynecological Laparoscopy

Muscle Relaxation

Kuwait
Yonsei University

Completed

The Effect of Deep Neuromuscular Blockade on Postoperative Shoulder Tip Pain After Laparoscopic Cholecystectomy

Pain, Postoperative

Korea, Republic of
Tampere University Hospital

Completed

Electromyographic (EMG) on the Anaesthesia Monitor

Anaesthesia

Finland
Chosun University Hospital

Completed

Current Intensity for the Obturator Nerve Block (Current_ONB)

Bladder Tumor

Korea, Republic of
Daegu Catholic University Medical Center

Completed

Muscle Relaxants on Efficacy of LMA Insertion (LMA_MR)

Anesthesia Intubation Complication

Korea, Republic of
Huang-wei LV

Unknown

Interaction of Statins and Nondepolarizing Muscle Relaxants

Pain

China
Merck Sharp & Dohme LLC

Completed

A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part B: Caucasian Participants (P05971)

Anesthesia, General
Merck Sharp & Dohme LLC

Completed

Rocuronium Plus Sugammadex Versus Succinylcholine Alone in Participants Undergoing Short Surgical Procedures (19.4.319)(P05700 AM2)(COMPLETED)

Neuromuscular Blockade
Air Force Military Medical University, China

Unknown

Muscle Relax Affects Outcomes of Robotic Surgery (MORE)

Postoperative Complications | General Anesthesia
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Early Quality of Recovery (RECOVER)

Pneumoperitoneum | Surgery | Neuromuscular Blockade

Netherlands
Craig Curry
MaineHealth; Spectrum Medical Group Anesthesiology

Completed

Does Deep Neuromuscular Blockade Improve Operating Conditions During Total Hip Replacements?

Arthropathy of Hip

United States
University of Washington

Completed

Mask Ventilation Before and After Neuromuscular Blockade

Anesthesia

United States
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

The Effect of Low Pressure Pneumoperitoneum During Laparoscopic Colorectal Surgery on Innate Immune Homeostasis. (RECOVER-PLUS)

Pneumoperitoneum | Surgery | Neuromuscular Blockade | Immune Suppression

Netherlands
Rainer Lenhardt

Withdrawn

Does Depth of Neuromuscular Blockade (NMB) Affect Surgical Conditions in Obese Patients Undergoing Robotic Surgery (NMB)

Urologic Diseases | GYN Disorders

United States
NYU Langone Health

Completed

Determination of TOF Test Threshold for Obtaining Reliable Pedicle Screw Stimulation Test During Lumbar Spine Surgery

Neuromuscular Blockade

United States
Merck Sharp & Dohme LLC

Completed

Sugammadex After Continuous Infusion of Rocuronium During Sevoflurane and Propofol Anesthesia (P05949; MK-8616-028)

Anesthesia, General
Clinical Hospital Centre Zagreb

Enrolling by invitation

General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery

Muscle Weakness | General Anaesthesia | Rocuronium

Croatia
Merck Sharp & Dohme LLC

Completed

Dose-Finding Pediatric and Adult Trial With Sugammadex (Org 25969, MK-8616, SCH 900616) (19.4.306) (MK-8616-034) (P05961)

Anesthesia
University Hospital of Split

Recruiting

Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants

Anesthesia | Neuromuscular Blockade | Intraoperative Bleeding | Anesthesia Complication | Post Operative Hemorrhage | Intraoperative Blood Loss

Croatia
Korea University Anam Hospital

Unknown

Evaluation of EEG With Respect to the Change of Depth of Anesthesia During General Anesthesia

Anesthesia
Peking University First Hospital
Xiangya Hospital of Central South University; Peking Union Medical College... and other collaborators

Unknown

A Study of Residual Curarization Incidence in China

Perioperative/Postoperative Complications | PORC (Postoperative Residual Curarization)

China
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025)

Anesthesia, General
Korea University Anam Hospital

Unknown

The Effect of no Muscle Relaxant Versus Reduced-dose Rocuronium on Anesthesia in Adenotonsillectomy

Muscle Relaxants
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774)

Anesthesia
The First Affiliated Hospital with Nanjing Medical...
Wu Jieping Medical Foundation

Completed

Study on the Level of Neuromuscular Blockade

Neuromuscular Blockade

China
Merck Sharp & Dohme LLC

Completed

Study of Efficacy, Pharmacokinetics and Safety of Continuous Intravenous Infusion of Org 9426 (Study P05977)

Anesthesia
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Investigation of Sugammadex in Outpatient Urological Procedures

Bladder Cancer | Malignant Neoplasms of Urinary Tract

United States
R-Pharm
Synergy Research Inc.

Completed

Comparative Clinical Study of Efficacy and Safety of Remimazolam and Propofol in Patients Undergoing Elective Surgery Under General Anaesthesia

General Anaesthesia

Russian Federation
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Sugammadex Dosed According to Actual Body Weight (ABW) or Ideal Body Weight (IBW) in Reversal of Neuromuscular Blockade (NMB) in Morbidly Obese Participants (MK-8616-146)

Neuromuscular Blockade

United States, Austria, Belgium, Denmark, Germany
Institut Jantung Negara

Completed

Rocuronium vs Cis-atracurium: Do Rocuronium Still 'ROCKS' In Coronary Artery Bypass Grafting

Coronary Artery Disease | Neuromuscular Blockade | Coronary Artery Bypass Grafting | Postoperative Pulmonary Complication | Postoperative Pulmonary Atelectasis | Hypothermic Cardiopulmonary Bypass

Malaysia
Merck Sharp & Dohme LLC

Completed

Comparison of Sugammadex With Neostigmine During Laparoscopic Cholecystectomy or Appendectomy (P05699)

Anesthesia, General

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