Search clinical trials for: Roflumilast escalation dosage

Total 6335 results

Asan Medical Center

Unknown

Strategy to Improve Adherence of Roflumilast

Chronic Obstructive Pulmonary Disease

Korea, Republic of
Fundación Pública Andaluza Progreso y Salud

Completed

Roflumilast Safety Administered Once a Day on Alternate Days for Two Weeks Compared to the Usual Dosage Once Daily (ROFLU2011)

Chronic Obstructive Pulmonary Disease (COPD)

Spain
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Management of LLN Metastasis in Locally Advanced Rectal Cancer: A Prospective Radiation Dose Escalation Study

Rectal Cancer

China
University of Miami
Forest Laboratories

Completed

Effect of Roflumilast on Airway Blood Flow as an Expression of Airway Inflammation in COPD

COPD

United States
Weill Medical College of Cornell University

Active, not recruiting

PRE-ProstAtectomy MRI-GuidEd Stereotactic Body RadioTherapy for High-Risk Prostate Cancer Trial (PREPARE SBRT) (PREPARE SBRT)

Prostate Cancer

United States
Cliniques universitaires Saint-Luc- Université...

Unknown

Molecular Imaging-based Dose Escalation in HPV Negative Patients With Locally Advanced SCC of the Oropharynx

Head and Neck Cancer

Belgium
University Hospital Olomouc
University Hospital Ostrava; Masaryk Memorial Cancer Institute

Recruiting

FMISO-based Adaptive Radiotherapy for Head and Neck Cancer (FARHEAD)

Hypoxia | Head and Neck Cancer | Dose Escalation | FMISO

Czechia
Universitaire Ziekenhuizen KU Leuven
KU Leuven; Stichting tegen Kanker

Recruiting

Dose De-escalation and Sentinel LN Mapping Driven Radiotherapy of Contralateral Neck in Ipsilateral Node Positive HNSCC (SEMIRAHN)

Squamous Cell Carcinoma of Head and Neck

Belgium
Royal North Shore Hospital

Recruiting

Advanced Techniques For Single-fraction Palliative Radiotherapy Versus Standard Multi Fraction Radiation (ASPIRE_Multi)

Palliative Radiotherapy

Australia
National Cancer Institute, Egypt

Recruiting

Multimodality- Adapted Dose Modification in Head and Neck Cancer Radiation Therapy (MART)

Head and Neck Cancer

Egypt
Istituto Clinico Humanitas

Recruiting

SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions (STRILL)

Non Small Cell Lung Cancer | Lung Metastases

Italy
Emory University

Completed

Phase I Trial of Stereotactic Radiosurgery Following Surgical Resection of Brain Metastases

Brain Metastasis | Neoplasm

United States
Arcutis Biotherapeutics, Inc.

Completed

Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (INTEGUMENT-II)

Atopic Dermatitis Eczema

United States, Canada
FLUIDDA nv

Terminated

Evaluation of the Effect of Roflumilast in Hyperinflated COPD Patients Using Functional Respiratory Imaging

Pulmonary Disease, Chronic Obstructive

Belgium
Radboud University Medical Center

Terminated

Individualized Dose Prescription in Advanced Stage Lung Cancer Patients Using Modern (Chemo)Radiotherapy (IDEAL-VMAT)

Stage III Non-small Cell Lung Cancer | Individualized Radiation Dose Escalation

Netherlands
AstraZeneca

Completed

OPUS Study: Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (BY217/M2-111)

Chronic Obstructive Pulmonary Disease | COPD

United States, France, Poland, South Africa, Canada, Germany
AstraZeneca

Completed

The HERO-study: Effects of Roflumilast in Patients With COPD (Chronic Obstructive Pulmonary Disease) (BY217/M2-121)

Chronic Obstructive Pulmonary Disease, COPD

France, Poland, South Africa, Spain, United States, Canada, United Kingdom
AstraZeneca

Completed

Efficacy and Safety of Roflumilast in Patients With Asthma (BY217/M2-012)

Asthma

United States, Argentina, Colombia, Mexico, Peru
Seoul National University Bundang Hospital

Unknown

Phase2, Single Group, Open Clinical Trial to Evaluate the Efficacy and Safety of Roflumilast in Symptomatic Bronchiectasis Patients

Symptomatic Bronchiectasis

Korea, Republic of
University of Pennsylvania

Completed

Ghrelin Dose Finding In Frail Elderly

The Frailty Syndrome

United States
Hinova Pharmaceuticals Inc.

Recruiting

A Phase I Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in mCRPC Patients

Metastatic Castration-resistant Prostate Cancer

China
AstraZeneca

Completed

Long-term Observational Study of the Safety of Roflumilast

COPD

Sweden, Germany, United States, Norway
AstraZeneca

Completed

The FLASH Study: A Study of Roflumilast Versus Placebo in Patients With Asthma (BY217/M2-023)

Asthma

United States, Russian Federation, Ukraine
AstraZeneca

Completed

Pharmacokinetic Study of Single and Repeated Dose of Roflumilast 500 µg , in Healthy Chinese Subjects

Chronic Obstructive Pulmonary Disease

China
AstraZeneca

Completed

Efficacy of 500µg Roflumilast Once Daily Versus Placebo Over 12 Weeks in Patients With Diabetes Mellitus Type 2. A Double Blind, Parallel Group, Proof of Concept Clinical Study (FORTUNA)

Diabetes Mellitus Type 2
FLUIDDA nv

Completed

Evaluation With CT Scan of Possible Changes in Airways After Treatment With Daxas® in Severe Chronic Obstructive Pulmonary Disease Patients

Pulmonary Disease, Chronic Obstructive

Belgium
Umeå University

Completed

Dose Escalation With SIB to Intraprostatic/Lymphatic GTV in High Risk Prostate Cancer (PARAPLY-1)

Prostatic Neoplasms | Lymphatic Metastasis

Sweden
Vanderbilt University Medical Center

Withdrawn

Multiple Ascending Dose Putative Cognitive Enhancer VU319

Cognitive Impairment

United States
Hinova Pharmaceuticals Aus Pty Ltd

Completed

A Study to Assess the Safety, Pharmacokinetics, and Anti-Tumor Activity of Oral HP518 in Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-resistant Prostate Cancer

Australia
Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent

Completed

Dose De-escalation to the Elective Nodal Sites in Head and Neck Cancer

Head and Neck Cancer

Belgium
AstraZeneca
Pfizer

Completed

Efficacy and Safety of Oral Roflumilast Taken With Low Dose Inhaled Corticosteroids in Patients With Asthma (12 to 70 y) (BY217/M2-013)

Asthma

United States, Austria, Croatia, Czech Republic, Finland, France, Greece, Hungary, India, Ireland, Italy, New Zealand, Norway, Pakistan, Philippines, Poland, Portugal, Russian Federation, Singapore, South Africa, Spain, Taiwan, Thai... and more
AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease. Ratio-Study. (BY217/M2-112)

Chronic Obstructive Pulmonary Disease | COPD

Austria, France, Hungary, Italy, Poland, Portugal, Russian Federation, South Africa, Spain, Canada, United Kingdom, Australia, Netherlands, Switzerland
AstraZeneca

Completed

Effect of Roflumilast on Pulmonary Function and Respiratory Symptoms in Patients With Chronic Obstructive Pulmonary Disease (COPD) (BY217/M2-110)

Chronic Obstructive Pulmonary Disease | COPD

United States, Argentina, Canada, Colombia, Mexico, Peru
AstraZeneca

Completed

Efficacy and Safety of Roflumilast Taken in the Morning or Evening in Patients With Stable Asthma (12 to 70 y) (BY217/M2-015)

Asthma

France, South Africa, Spain, Australia, Belgium
University of California, Davis

Terminated

Phosphodiesterase 4 Inhibitor, Roflumilast, and the Effects of Inhibition in Severe Asthma

Asthma

United States
Bispebjerg Hospital

Completed

Efficacy of Roflumilast in the Treatment of Psoriasis (PSORRO)

Psoriasis

Denmark
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Terminated

A Multicenter Randomized Double-blind Clinical Study Evaluated the Safety, Pharmacokinetic and Pharmacodynamic Characteristics of Roflumilast in COPD Patients

Chronic Obstructive Pulmonary Disease

China
AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The AURA Study (BY217/M2-124)

Chronic Obstructive Pulmonary Disease (COPD)

France, Germany, United Kingdom, United States, Australia, Austria, Brazil, Hungary, New Zealand, Romania, Russian Federation
AstraZeneca

Completed

Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Combinations of Long-acting β2-agonists (LABA) and Inhaled Glucocorticosteroid (ICS) (REACT)

Chronic Obstructive Pulmonary Disease

Korea, Republic of, Austria, Belgium, Germany, Greece, Russian Federation, Australia, Brazil, Canada, Denmark, France, Hungary, Israel, Italy, Netherlands, Poland, Slovakia, South Africa, Spain, Turkey, United Kingdom
AstraZeneca

Completed

Efficacy and Safety of Oral Roflumilast Taken Once Daily in Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (BY217/M2-119)

COPD

Korea, Republic of, Malaysia, Taiwan, Hong Kong, Philippines
Domain Therapeutics SA

Recruiting

DT-9081 Study in Participants With Advanced, Recurrent or Metastatic Solid Tumours (EPRAD)

Solid Tumor, Adult

France, Belgium
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO) (CARPASCIO)

Non-Hodgkin's Lymphoma | B-Cell ALL | B-Cell CLL

United States
Benitec Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Oculopharyngeal Muscular Dystrophy

United States
The University of Texas Health Science Center at...

Completed

Study of Roflumilast in Combination With Standard Chemotherapy for High-risk Diffuse Large B-cell Lymphoma

Lymphoma, B-Cell

United States
Dermatology Consulting Services, PLLC

Completed

Evaluation of the Safety and Efficacy of Topical Roflumilast Cream in the Treatment of Facial Papulopustular Rosacea

Rosacea

United States
AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The HERMES Study (BY217/M2-125)

Chronic Obstructive Pulmonary Disease (COPD)

Germany, Spain, United States, Canada, India, Italy, Poland, South Africa
Qualigen Theraputics, Inc.
Translational Drug Development

Recruiting

Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors

Solid Tumor

United States
Maastricht Radiation Oncology

Completed

HI-CHART:Feasibility of High-Dose Accelerated Conformal Radiotherapy

Non-Small-Cell Lung Carcinoma

Netherlands
Royal North Shore Hospital

Completed

Early Investigation of High Precision Radiotherapy Prior to Commencing Standard Radiotherapy for Prostate Cancer (BOOSTER)

Prostate Cancer

Australia
Acea Bio (Hangzhou) Co., Ltd.

Unknown

Safety Study of FLP Injection to Treat Tumor Patients

Advanced Cancer

China

Search clinical trials for: Roflumilast escalation dosage

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