Search clinical trials for: SKI-606

Total 4248 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI); Pfizer

Terminated

Bosutinib in Treating Patients With Chronic Myeloid Leukemia in Chronic Phase After Frontline TKI Failure

Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Blasts Under 15 Percent of Bone Marrow Nucleated Cells | Blasts Under 15 Percent of Peripheral Blood White Cells | Blasts Under 30 Percent of Bone Marrow Nucleated Cells | Blasts Under 30 Percent of Peripheral Blood White Cells

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating SKI-606 in Subject With Solid Tumors

Tumors
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating The Mass Balance And Metabolic Disposition Of SKI-606

Healthy Subjects

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating SKI-606 Administered to Healthy Subjects

Healthy

Netherlands
Massachusetts General Hospital
Pfizer; Dana-Farber Cancer Institute; Brigham and Women's Hospital

Completed

Bosutinib in Adult Patients With Recurrent Glioblastoma

Glioblastoma

United States
Pfizer

Completed

Study Evaluating SKI-606 (Bosutinib) In Subjects With Breast Cancer

Breast Neoplasms | Neoplasm Metastasis

United States, Ukraine, Russian Federation, Hong Kong, France, Australia, Poland, Malta
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Two Different Tablet Formulations Of Bosutinib Under Fed Conditions

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Comparing Two Different Tablet Formulations Of Bosutinib

Healthy

United States
Pfizer

Completed

Bioequivalence And Food Effect Study Of Bosutinib In Healthy Subjects

Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia (CML)

Singapore
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating 3 New Formulations of SKI-606 in Healthy Adult Subjects

Healthy

United States
Pfizer

Completed

Study Evaluating SKI-606 (Bosutinib) In Philadelphia Chromosome Positive Leukemias

Chronic Myeloid Leukemia

United States, Spain, Australia, Canada, Hong Kong, Singapore, United Kingdom, Germany, Netherlands, Chile, India, South Africa, Sweden, Peru, Argentina, Italy, Austria, Colombia, Brazil, China, Finland, Hungary, Korea, Republic of, M... and more
Pfizer

Completed

Study Evaluating SKI-606 (Bosutinib) In Japanese Subjects With Philadelphia Chromosome Positive Leukemias

Chronic Myelogenous Leukemia

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Drug Interaction Between Multiple Doses of Ketoconazole and a Single Dose of SKI-606

Healthy

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Ascending Single-Dose Of Bosutinib Administered With Multiple Doses Of Ketoconazole To Healthy Subjects

Leukemia | Breast Cancer | Tumors

Netherlands
University of Milano Bicocca
IRCCS San Raffaele

Completed

Allogeneic Stem Cell Transplantation in Chronic Myeloid Leukemia Failing TKIs Therapy

Leukemia | BCR-ABL Positive | Myelogenous | Chronic

Italy
Georgetown University
Alzheimer's Association

Completed

Impact of Bosutinib on Safety, Tolerability, Biomarkers and Clinical Outcomes in Dementia With Lewy Bodies

Dementia With Lewy Bodies

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Axitinib and Bosutinib in Treating Patients With Chronic, Accelerated, or Blastic Phase Chronic Myeloid Leukemia

Accelerated Phase Chronic Myelogenous Leukemia (CML) | Blast Phase Chronic Myelogenous Leukemia (CML) | Chronic Phase Phase Chronic Myelogenous Leukemia (CML) | Philadelphia Chromosome Positive (Ph+) Phase Chronic Myelogenous Leukemia (CML)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Phase I/II Study of Bosutinib in Combination With Inotuzumab Ozogamicin in CD22-positive PC Positive ALL and CML

Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | B Acute Lymphoblastic Leukemia With t(9;22)(q34... and other conditions

United States
Scarless Laboratories, Inc.

Recruiting

Dose Regimen Study of SLI-F06 in Healthy Volunteers

Scar | Wound Healing

United States
Scarless Laboratories, Inc.
ethica Clinical Research Inc.

Completed

Safety and Efficacy of SLI-F06 in Wound Healing and Scar Appearance

Scars

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
Pfizer
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML

Chronic Myeloid Leukemia

France, United States, Spain, Belgium, Singapore, Poland, Canada, Japan, United Kingdom, Taiwan, Hungary, Germany, Argentina, Russian Federation, Turkey, Colombia, Italy, South Africa, Brazil, Chile, China, Hong Kong, India, Korea, Republic... and more
University College, London
Dermatrust

Withdrawn

Investigating Immune Mechanisms in Atopic Eczema

Atopic Dermatitis

United Kingdom
Orlucent, Inc

Unknown

Skin Fluorescent Imaging (SFI) System in Patients With Nevi

Nevus | Dysplasia; Epithelial

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating The Potential Effect Of Lansoprazole On The Pharmacokinetics Of Bosutinib In Healthy Subjects

Healthy

United States
Mersin University

Completed

Skin-to-skin Contact Time and Maternal Psychology

Skin to Skin Contact

Turkey
National Taiwan University Hospital Hsin-Chu Branch

Unknown

Skin-to-Skin Contact Start Time in Newborns Sucking and Mother's Breastfeeding Willingness and Parent-Infant Attachment Associated

Mother-Child Relationship

Taiwan
National University, Singapore
National Medical Research Council (NMRC), Singapore

Recruiting

The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) Study (SINGER)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Cognitive Impairment | Dementia | Alzheimer Disease | Cognition Disorder | Vascular Cognitive Impairment

Singapore
Dr. Reddy's Laboratories Limited

Completed

A Study to Assess the Efficacy and Safety of PPC-06 (Tepilamide Fumarate)

Psoriasis

United States
Zhejiang University

Recruiting

A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China (HERITAGE)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Cognitive Impairment | Alzheimer Disease | Mental Disorder | Cognition Disorder | Vascular Cognitive Impairment | Dement

China
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating The Effect of Bosutinib (SKI-606) On Cardiac Repolarization (Rhythms Of The Heart)

Healthy Subjects

United States
Medical University of Vienna

Completed

Posterior Capsule Opacification and Optical Quality of Different Hydrophobic Acrylic Intraocular Lenses

Posterior Capsule Opacification
Duke University
National Institute on Drug Abuse (NIDA)

Recruiting

Low Nicotine Cigarettes, Smoking, and Chronic Pain (VLNCPain)

Chronic Pain | Smoking, Cigarette

United States
China Medical University Hospital
Ministry of Science and Technology, Taiwan

Active, not recruiting

Strong Kidney Initiative Trial for Dialysis Care Quality (SKI)

Hemodialysis Complication

Taiwan
Oscotec Inc.
PPD

Completed

Study to Find a Safe and Effective Dose of SKI-G-801 in the Treatment of Patients With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Oscotec Inc.

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SKI-G-801 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Korea, Republic of
Oscotec Inc.

Completed

A Study of the Absorption, Metabolism, and Excretion of [14C]-SKI-O-703 Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
University of Connecticut

Completed

Brief HIV Prevention Counseling for STI Patients in South Africa

Sexually Transmitted Infections

United States
Oscotec Inc.

Unknown

A Study to Evaluate the Effectiveness and Safety of SKI-O-703 in Patients Experiencing Active Rheumatoid Arthritis Despite Treatment With Conventional Therapies.

Rheumatoid Arthritis

United States, Czechia, Poland, Russian Federation, Ukraine
University of Oxford

Completed

Heterologous Effects of BCG in Healthy UK Adults

Tuberculosis

United Kingdom
Oscotec Inc.
PPD

Completed

Safety, Tolerability, and Pharmacokinetics of a Single Oral Dose of SKI-O-703 in Healthy Volunteers

Rheumatoid Arthritis

United States
Oscotec Inc.
PPD

Completed

Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of SKI-O-703 in Healthy Volunteers

Arthritis, Rheumatoid

United States
Oscotec Inc.

Completed

Study of Oral SKI-O-703, SYK Inhibitor, in Patients With Persistent and Chronic Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia

United States, Greece, Korea, Republic of, Poland, Spain
AbbVie
Boehringer Ingelheim

Completed

A Long Term Extension Trial of BI 655066/ABBV-066 (Risankizumab), in Patients With Moderately to Severely Active Crohn's Disease

Crohn Disease

United States, Belgium, Canada, Germany, Korea, Republic of, Netherlands, Poland, Spain, United Kingdom
Vaxon Biotech

Completed

Safety Study of Vx006 Vaccine in Solid Tumor Patients

Solid Tumor

Greece
Kezar Life Sciences, Inc.

Completed

Open-label Extension to the Phase 2 Crossover Study (PRESIDIO) Evaluating KZR-616 in Patients With PM and DM.

Dermatomyositis | Polymyositis

United States
Takeda

Completed

Phase 1 TAK-906 Single and Multiple Ascending Dose Study in Japanese Healthy Male Participants

Japanese Healthy Adult Male Participants

Japan
DICE Therapeutics, Inc.

Completed

Mass Balance and Pharmacokinetics (PK) of [14C]-DC-806 in Healthy Male Participants

Healthy Volunteers

Netherlands
Stony Brook University
University of Denver

Completed

Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19

Depression

United States
Rothman Institute Orthopaedics

Enrolling by invitation

Wound Healing in Primary TKA

Total Knee Replacement | Wound Complication

United States

Search clinical trials for: SKI-606

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