Search clinical trials for: second-line chemotherapy

Total 12176 results

Shanghai Gynecologic Oncology Group
Zhejiang Cancer Hospital; Sun Yat-sen University; Fudan University; Shanghai Zhongshan...

Active, not recruiting

Surgery or Chemotherapy in Recurrent Ovarian Cancer (SOC 1 Trial)?

Fallopian Tube Carcinoma | Ovarian Epithelial Cancer Recurrent | Primary Peritoneal Carcinoma

China
Boehringer Ingelheim

Completed

A Study in the United States Using Electronic Medical Records (EMR) to Assess Effectiveness of Afatinib (Gilotrif) Following Pembrolizumab and Chemotherapy in the Treatment of Metastatic Squamous Cell Carcinoma of the Lung

Squamous Non-small Cell Lung Cancer

United States
Hoffmann-La Roche

Completed

A Study of Herceptin (Trastuzumab) in Combination With 2nd-Line Chemotherapy in Patients With HER2 Positive Metastatic Breast Cancer.

Breast Cancer

Estonia, Hungary, Turkey, Israel, Slovakia, Bulgaria, Lithuania, Macedonia, The Former Yugoslav Republic of
Nanfang Hospital of Southern Medical University

Recruiting

The Effects of RFA in Combination With Second-line Chemotherapy and Bevacizumab on Unresectable CRLM

Colorectal Neoplasms Malignant

China
Grupo Espanol de Tumores Neuroendocrinos
Amgen

Not yet recruiting

Refractory Advanced diGestive Neuroendocrine Carcinomas Treated With tARlatamab (RAGNAR)

Advanced Neuroendocrine Carcinomas of The Digestive System | Advanced Neuroendocrine Carcinomas Unknown Primary Origin

Spain, France
Insel Gruppe AG, University Hospital Bern
European Organisation for Research and Treatment of Cancer - EORTC

Recruiting

Surgery for Recurrent Glioblastoma (RESURGE)

Glioblastoma

Germany, Switzerland, Austria, Greece, Italy, Portugal, Romania, Netherlands, Spain
Shu-Zhong Cui
Guangdong Provincial Hospital of Traditional Chinese Medicine; Chinese PLA... and other collaborators

Unknown

Efficacy of HIPEC Combined With Systemic Chemotherapy and CRS on Peritoneal Metastases From Gastric Cancer

Gastric Cancer | Peritoneal Carcinomatosis

China
Shanghai Pulmonary Hospital, Shanghai, China

Not yet recruiting

A Multicenter Real-World Cohort Study of Adebrelimab Injection in the Treatment of Extensive-Stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Peking University People's Hospital
Peking University Shougang Hospital

Completed

Clinical Evaluation of Neoadjuvant Chemotherapy for Primary Malignant Sarcomas That Originate in Bone (CESOFB-00)

Prognosis | Clinical Response | Histopathological Response

China
Celgene

Active, not recruiting

Connect® MM- The Multiple Myeloma Disease Registry

Multiple Myeloma

United States, Puerto Rico
Genentech, Inc.

Completed

A Study of Bevacizumab in Combination With First- or Second-Line Therapy in Subjects With Treated Brain Metastases Due to Non-Squamous NSCLC (PASSPORT)

Brain Neoplasms | Non-Small Cell Lung Cancer
Sun Yan
Peking University; Peking University Cancer Hospital & Institute

Unknown

Second-Line Chemotherapy Combined With Endostatin for Recurrent/Metastatic HN Epithelial Tumors (SLICER)

Head and Neck Neoplasms

China
Georgetown University
Cedars-Sinai Medical Center; Thomas Jefferson University; Sinai Health System; George... and other collaborators

Withdrawn

Molecularly Tailored Therapy to Standard of Care as Second-Line Therapy in Metastatic Pancreatic Cancer (PanCAN)

Metastatic Pancreatic Cancer

United States
National Cancer Institute, Naples

Active, not recruiting

PET/CT Scan as a Tool to Rationalize the Treatment of Patients With Advanced ColoRectal Cancer Undergoing First-line Medical Treatment (PETRA2 - CRC)

Colorectal Cancer Stage IV

Italy
AstraZeneca
Quintiles, Inc.

Completed

LUMINIST: LUng Cancer Molecular Insights Non Interventional Study (LUMINIST)

NSCLC

Bulgaria, France, Italy, Mexico, Peru, Russian Federation, Spain, Turkey, United Kingdom, Sweden, Poland, Ukraine, Chile, Hungary, Israel, Netherlands, Portugal, Romania, Germany, Austria, Belgium, Canada, Australia
Medical College of Wisconsin

Recruiting

Pancreatic Cancer Adaptive Neoadjuvant Chemotherapy Trial (PANC)

Pancreatic Cancer

United States
Central Hospital, Nancy, France

Not yet recruiting

Relevance and Efficiency of SecOnd Line Workup for Uveitis (RESOLVE)

Uveitis
Canadian Cancer Trials Group
Alliance for Clinical Trials in Oncology; NRG Oncology; ECOG-ACRIN Cancer Research... and other collaborators

Not yet recruiting

Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer (CURB2)

Non-small Cell Lung Cancer
Duke University

Completed

Ehealth: Second Life Impacts Diabetes Education & Self-Management (SLIDES)

Type 2 Diabetes

United States
Hoffmann-La Roche

Completed

A Study of First-line Maintenance Erlotinib Versus Erlotinib at Disease Progression in Participants With Advanced Non-Small Cell Lung Cancer (NSCLC) Who Have Not Progressed Following Platinum-Based Chemotherapy

Non-Squamous Non-Small Cell Lung Cancer

China, Korea, Republic of, South Africa, Taiwan, Hungary, France, Netherlands, United States, Bulgaria, Slovakia, Canada, Italy, Brazil, Thailand, Romania, Lithuania, Poland, Latvia, Ukraine, Czech Republic
Henan Cancer Hospital

Recruiting

A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)

NSCLC | Brain Metastases | Leptomeningeal Metastasis

China
Novartis Pharmaceuticals

Completed

A Global Study of the Efficacy and Safety of Midostaurin + Chemotherapy in Newly Diagnosed Patients With FLT3 Mutation Negative (FLT3-MN) Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML)

United States, Spain, Belgium, Germany, Japan, Taiwan, Turkey, Italy, Australia, Austria, Switzerland, Israel, Bulgaria, France, Norway, Brazil, Poland, Portugal, Czechia, Argentina
Liqiang Zhong

Unknown

Clinical Study of Apatinib Combined With Second - Line Chemotherapy for Metastatic Colorectal Cancer

Colorectal Neoplasms
Hebei Tumor Hospital

Unknown

Safety and Efficacy of Ginsenoside Rg3 in Combination With First-line Chemotherapy in Advanced Gastric Cancer

Self Efficacy

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Not yet recruiting

Study of DP303c Injection in Patients With Advanced or Metastatic Gastric Cancer

Gastric Cancer
Centre Oscar Lambret
University Hospital, Lille

Terminated

Correlation Between Tissue and Plasmatic EGFR in CBNPC With EGFR Mutation or Predictive Factor of EGFR Mutation (CONCORDE)

Nsclc

France
Regina Elena Cancer Institute
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; University of... and other collaborators

Active, not recruiting

Prospective Validation of a DNA Damage Repair-Hippo Pathway Signature in Patients With Advanced Gastric Cancer

Gastric Cancer | DNA Damage

Italy
The First Hospital of Jilin University
First Affiliated Hospital Xi'an Jiaotong University; Qingdao University; First... and other collaborators

Recruiting

Sequential Neo-adjuvant Chemotherapy Followed by Capecitabine Vs. Conventional Adjuvant Chemotherapy in Breast Cancer (NACVCAC)

Breast Neoplasm Female

China
Novartis Pharmaceuticals

Completed

A Non-interventional Study for Women With HR-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer to Evaluate the Real-world Effectiveness of Treatment Algorithms Beginning With Ribociclib + AI/FUL, or With Endocrine Therapy or Chemotherapy as First Line Treatment (RIBANNA)

Breast Cancer

Germany
Mark Vincent
AstraZeneca

Recruiting

Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer with Osimertinib Third-line Rechallenge (OCELOT)

Non-Small Cell Lung Cancer

Canada
University of Kansas Medical Center

Completed

A Virtual Reality Intervention to Improve Weight Maintenance

Weight Loss

United States
Zhou Fuxiang

Not yet recruiting

Umbilical Cord Blood Derived MAK Immune Cells Combined With Standard Second-Line Treatments for Hepatobiliary and Pancreatic Malignancies

Stage IV Pancreatic Cancer | Hepatocellular Carcinoma , Cholangiocarcinoma

China
Université Catholique de Louvain

Completed

Hyperglycemia and (Pre)Diabetes in Pediatric Renal and Liver Transplantation. (DIAB-GRAFT)

Diabetes Mellitus Risk

Belgium
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial

Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Ovarian Serous Adenocarcinoma | Primary Peritoneal Serous Adenocarcinoma | Primary Peritoneal Clear... and other conditions

United States
Qilu Hospital of Shandong University

Recruiting

First-Line and Neoadjuvant Immunotherapy for Gastric Cancer

Advanced Gastric Cancer | Locally Advanced Gastric Carcinoma

China
Jian Li

Recruiting

JAB-21822 Combined With Chemotherapy in Second-line KRAS G12C CRC

Colorectal Cancer

China
The First Affiliated Hospital of Nanchang University
The First Hospital of Nanchang

Recruiting

Neoantigen-loaded DC Vaccine and Conventional Second-line Therapy for CRC Progressed After First-line Treatment

Colorectal Cancer (CRC)

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Second Line Chemotherapy FOLFIRINOX in Irresectable Cholangiocarcinoma (4CC)

Cholangiocarcinoma

Netherlands
The First Affiliated Hospital of Nanchang University
The First Hospital of Nanchang

Recruiting

Neoantigen-based Peptide Vaccine and Conventional Second-line Therapy for CRC Progressed After First-line Treatment

Colorectal Cancer (CRC)

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Liver Surgery and Chemotherapy in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery and Lung Metastases That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Malignant Neoplasm in the Liver | Metastatic Colorectal Carcinoma | Metastatic Malignant Neoplasm in the Lung | Resectable Colorectal Carcinoma

United States
Johns Hopkins University
Centers for Disease Control and Prevention

Completed

Preventing Falls Among Older Fallers to Test the Effect of LIVE-LiFE, a Home-Based, Tailored Fall Prevention Program (LIVE-LiFE)

Fall Prevention

United States
Oslo University Hospital

Recruiting

EXtended CriteriA Treatment for LIver Metastases and Heavy Tumour BURden (EXCALIBUR3)

Colorectal Cancer | Liver Metastases

Norway
Ain Shams University

Completed

Efficacy of Aleo Vera Use in Prevention and Treatment of Chemotherapy-Induced Oral Mucositis in a Group of Egyptian Children with Acute Leukemia

Oral Mucositis

Egypt
Second Affiliated Hospital, School of Medicine,...

Recruiting

Stereotactic Body Radiotherapy for Oligo-Progression Metastatic Non-Small Cell Lung Cancer (OPPRESS)

Metastatic Non-Small Cell Lung Cancer | NSCLC Stage IV | OligoProgressive Metastatic Disease

China
University of Utah

Completed

Radiation Therapy and Capecitabine/Oxaliplatin Chemotherapy in the Treatment of Locally Advanced Pancreas Adenocarcinoma

Cancer | Pancreas

United States
Medical University of Graz
Medical University of Vienna; Medical University Innsbruck; Krankenhaus Barmherzige... and other collaborators

Recruiting

Austrian Registry for Evaluation of Treatment Patterns and Outcome in Patients with Advanced Pancreatic Ductal Adenocarcinoma (PDAC) (ADPACA)

Pancreatic Cancer | Advanced Pancreatic Carcinoma

Austria
Transgene

Completed

Immunotherapy With TG4010 in Patients With Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

France, Germany, Hungary, Poland
Beijing Immunochina Medical Science & Technology...

Recruiting

Safety and Efficacy Evaluation of IM83 CAR-T Cells for Patients With Advanced Liver Tumors

Liver Cancer

China
Lei Li

Recruiting

NAC Followed by RH for the Treatment of LACC

Laparotomy | Laparoscopy | Locally Advanced Cervical Cancer | Neoadjuvant Chemotherapy | Adjuvant Therapy | Concurrent Chemoradiotherapy | Radical Hysterectomy | Objective Response | Systematic Chemotherapy

China
Bausch & Lomb Incorporated

Completed

Loteprednol Etabonate in an Ophthalmic Base vs Vehicle for the Treatment of Inflammation Following Cataract Surgery

Ocular Inflammation

United States

Search clinical trials for: second-line chemotherapy

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