Search clinical trials for: Simulect®

Total 13734 results

Drexel University College of Medicine
Novartis

Terminated

Study to Evaluate the Safety of Chronic Administration of Simulect to Subjects Receiving a First Kidney Transplant (Simulect)

End Stage Renal Disease

United States
Chipscreen Biosciences, Ltd.

Recruiting

A Phase II Clinical Trial of Chiglitazar for NASH

NASH

China
Luye Pharma Group Ltd.

Completed

A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
Indiana University School of Medicine

Completed

Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer

Multiple Myeloma | Non-Hodgkin's Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Anemia, Aplastic | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Myelodysplasia | Hemoglobinuria, Paroxysmal | Hodgkin's Disease

United States
Novartis Pharmaceuticals

Completed

A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients (SIMCER)

Liver Transplantation

France
Cerimon Pharmaceuticals

Completed

Basiliximab in Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Poland, Belgium, United Kingdom, Czech Republic, Russian Federation, Slovakia, Ukraine, India
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Completed

A Clinical Study on the Safety and Efficacy of GP681 Tablets in the Treatment of Uncomplicated Acute Influenza

Influenza

China
Xiyuan Hospital of China Academy of Chinese Medical...
The First Affiliated Hospital of Henan University of Traditional Chinese... and other collaborators

Recruiting

Efficacy and Safety of WPQW Granule for Overlap of NERD and IBS-D

Non-erosive Reflux Disease | Diarrhea-Predominant Irritable Bowel Syndrome

China
Xiyuan Hospital of China Academy of Chinese Medical...
First Affiliated Hospital of Heilongjiang Chinese Medicine University; Liuzhou... and other collaborators

Recruiting

Assessment on Effects of Tongjiang Granule in Treating Nonerosive Reflux Disease Overlapping Epigastric Pain Syndrome

Gastroesophageal Reflux | Functional Dysphonia

China
Cerimon Pharmaceuticals
PPD

Terminated

The Safety and Efficacy of Basiliximab as Maintenance Therapy in Subjects With Stable, Noninfectious Uveitis (BSX-003)

Non-infectious Uveitis

United States
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Oral Doses of HRS-7085 Tablets in Healthy Subjects, With Assessment of Food Effects

Inflammatory Bowel Disease
Fort Worth Clinical Sciences Working Group
TCU and UNTHSC School of Medicine

Not yet recruiting

Exploratory Regimen of Basiliximab for Treatment of Pulmonary Cytokine Storm in SARS-CoV-2 Hospitalized Adult Patients (FWCSWG-IL-2)

SARS-CoV2 Infection | Cytokine Storm | SARS-CoV-2 Acute Respiratory Disease
Coordinación de Investigación en Salud, Mexico

Completed

Basiliximab vs Low-dose Thymoglobulin Induction Therapy in Low Risk Kidney Transplant Patients

Kidney Transplant Rejection | Kidney Transplant; Complications

Mexico
Qianfoshan Hospital

Not yet recruiting

Integrated Traditional Chinese and Clinical Medicine for Chronic Hepatitis B and Its Complication

Hepatic Encephalopathy | Cirrhosis, Liver | Portosystemic Shunt

China
Novartis

Completed

Efficacy and Safety of Basiliximab, Cyclosporine/Cyclosporine Microemulsion, and Steroids in Pediatric de Novo Liver Transplant Recipients Avoiding Intraoperative Steroids

Liver Transplantation | Infection

Germany
Peking University People's Hospital

Unknown

Treatment of Posttraumatic Swelling and Pain With Zhi Kang Capsule

Soft Tissue Injuries

China
Mario Negri Institute for Pharmacological Research

Not yet recruiting

1 vs 7 RATG Infusions in Renal Transplantation (ONSET)

Kidney Replacement

Italy
Cerimon Pharmaceuticals

Terminated

Basiliximab Maintenance in Ulcerative Colitis

Ulcerative Colitis

United Kingdom
Luye Pharma Group Ltd.

Recruiting

Safety, Tolerability and Pharmacokinetic of Multiple-ascending Doses of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
King Faisal Specialist Hospital & Research Center

Recruiting

Standard Induction With Basiliximab Versus No-Induction in Low Immunological Risk Kidney Transplant Recipients

Kidney Transplantation

Saudi Arabia
SimpleC, LLC
University of Georgia; Advanced Medical Electronics

Completed

SimpleC Wellness Platform With Social Robot Interaction

Quality of Life | Cognitive Impairment | Dementia | Aging | Mild Cognitive Impairment | Engagement, Patient | Mood

United States
Astellas Pharma Global Development, Inc.
Kyowa Kirin Co., Ltd.

Completed

A Study to Assess the Efficacy and Safety of ASKP1240 in de Novo Kidney Transplant Recipients

Kidney Transplantation

United States
Novartis Pharmaceuticals

Completed

Pharmacodynamics, Efficacy and Safety of Basiliximab 40 or 80 mg in Combination With Ciclosporine Microemulsion or Everolimus, in Adult Low Risk de Novo Renal Transplant Recipients (IDEALE Study) (IDEALE)

Renal Transplantation

France
Gang Chen
Changhai Hospital; First Affiliated Hospital, Sun Yat-Sen University; The First... and other collaborators

Completed

Pediatric Induction Therapy in Kidney Transplantation (PINK)

Kidney Transplant Rejection | Pediatric Kidney Disease

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

To Compare the Efficacy and Safety of Oral SHR 7280 Tablets With Ganirelix Acetate Injection in Infertile Female Subjects

Infertile Female Subjects Undergoing Controlled Ovarian Hyperstimulation to Suppress Premature LH Surge and Prevent Early Ovulation

China
University of Pennsylvania

Terminated

Effect of Thymoglobulin Versus Basiliximab on Regulatory T Cell Function in Live Donor Kidney Transplant Recipients (TReg Kidney)

KIDNEY TRANSPLANTATION

United States
Astellas Pharma Global Development, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study to Assess the Efficacy and Safety of Bleselumab in Preventing the Recurrence of Focal Segmental Glomerulosclerosis in de Novo Kidney Transplant Recipients

Kidney Transplantation | Primary Focal Segmental Glomerulosclerosis (FSGS)

United States, Canada
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Prevention in Recipients With Primary IgA Nephropathy of Recurrence After Kidney Transplantation: ATG-F Versus Basiliximab as Induction Immunosuppressive Treatment (PIRAT)

Glomerulonephritis | IgAN

France
Nationwide Children's Hospital

Terminated

Infliximab and Basiliximab for Treatment of Steroid Refractory Acute Graft Versus Host Disease

Graft Versus Host Disease | Acute GVH Disease | Steroid Refractory GVHD

United States
Novartis Pharmaceuticals

Completed

Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients (CERTITEM)

Renal Interstitial Fibrosis

France
Genzyme, a Sanofi Company

Completed

An Open-label, Prospective, Randomized, Multi-center, Phase II Comparative Trial of Thymoglobulin Versus Simulect for the Prevention of Delayed Graft Function and Acute Allograft Rejection in Renal Allograft Recipients.

Cadaveric Donor Renal Transplantation | Acute Renal Allograft Rejection | Induction Therapy

United States, France, Spain, United Kingdom, Germany
Jiangsu Famous Medical Technology Co., Ltd.

Not yet recruiting

Clinical Study on Wuling Powder in Treating Metabolic Syndrome of Spleen Deficiency and Dampness

Metabolic Syndrome
University Hospital, Toulouse
Novartis; Neovii Biotech

Completed

Simulect Versus ATG in Sensitized Renal Transplant Patient (SATIR)

Renal Transplant Rejection

France
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation

Terminated

Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen

Kidney Transplantation | Primary Renal Allograft Candidate

United States
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation

Terminated

Optimization of NULOJIX® Usage As A Means of Avoiding CNI and Steroids in Renal Transplantation

Kidney Transplantation | Renal Transplantation

United States
CellTrans Inc.

Active, not recruiting

Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol

Type 1 Diabetes Mellitus

United States
University of Oxford
Genzyme, a Sanofi Company; Oxford University Hospitals NHS Trust

Unknown

Thymoglobulin Induction in Kidney Transplant Recipients (TIKT)

Kidney Transplantation | Ischemia-Reperfusion Injury

United Kingdom
China-Japan Friendship Hospital
Peking Union Medical College Hospital; Southwest Hospital, China; The First Affiliated... and other collaborators

Not yet recruiting

Post-marketing Re-evaluation of WangBi Granules for Rheumatoid Arthritis

Rheumatoid Arthritis
Novartis Pharmaceuticals

Completed

Preservation of Renal Function in Liver Transplant Recipients With Certican Therapy

Liver Transplantation

Germany, Netherlands, Switzerland, Austria
Armin Goralczyk

Unknown

Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation (CILT)

Liver Transplantation | Chronic Renal Insufficiency

Germany
National Institute of Allergy and Infectious Diseases...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Clinical...

Completed

Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation

Diabetes Mellitus, Type I

Sweden, Norway
Novartis

Completed

Everolimus in a Cyclosporine Microemulsion-free Regimen Compared to a Low-dose Cyclosporine Microemulsion Regimen, in de Novo Kidney Transplant Patients (CERTES02)

Organ Transplantation, Renal Transplantation
China National Center for Cardiovascular Diseases
Fuwai Yunnan Cardiovascular Hospital

Recruiting

HuoXin Pills Intervention on Patients With Coronary Heart Disease After Drug-Coated Balloon Implantation (HAPPY-DCB)

Coronary Heart Disease | Medicine, Chinese Traditional

China
The First Hospital of Jilin University

Not yet recruiting

Early Tirofiban Administration After Intravenous Thrombolysis in Acute Ischemic Stroke

Acute Ischemic Stroke
Dong-A ST Co., Ltd.

Completed

A Study to Demonstrate the Efficacy and Safety of Motilitone®

Functional Dyspepsia

Korea, Republic of
Galderma R&D

Completed

Cetaphil Restoraderm Effect on Young Children With Atopic Dermatitis

Atopic Dermatitis

Philippines, China
Chong Kun Dang Pharmaceutical

Completed

CKD-391 DDI : Atorvastatin and Ezetimibe in Healthy Volunteers

Healthy

Korea, Republic of
Novartis Pharmaceuticals

Completed

Study Investigating a Standard Regimen in de Novo Kidney Transplant Patients Versus a Calcineurin Inhibitor (CNI)-Free Regimen and a CNI-low Dose Regimen

Kidney Transplantation

Germany, Switzerland
Amir Azarpazhooh
Institut Straumann AG

Completed

Effect of Emdogain® on Soft Tissue Wound Healing

Periodontal Inflammation | Crown Lengthening

Canada
Novartis Pharmaceuticals

Completed

Inspiratory Flow Rates Achieved by the COPD Patients Through Breezhaler®, Ellipta® and Handihaler® Inhaler Devices

Pulmonary Disease, Chronic Obstructive (COPD)

Argentina

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