Search clinical trials for: Sitaxentan sodium/Placebo

Total 61413 results

Pfizer

Completed

Phase 1, Single and Multiple Doses Study of Sitaxentan in Japanese and Western Subjects

Healthy

United States
Pfizer

Terminated

A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed Thelin (PROSE)

Pulmonary Arterial Hypertension

Belgium, Germany, France
Pfizer

Completed

Pilot Chart Review Study Of Sitaxentan Sodium (Thelin) In Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension
Pfizer

Terminated

Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients

Hypertension, Pulmonary

Japan
Institut National de la Santé Et de la Recherche...

Terminated

Study on the Effects of Sitaxsentan on Airway Remodeling in Patients With Severe Asthma (Sitax)

Effect of Sitaxsentan on Airway Remodeling in Severe Asthma

France
Pfizer

Terminated

A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients

Hypertension, Pulmonary

Japan
Pfizer

Terminated

A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients With Pulmonary Arterial Hypertension (STRIDE-3)

Pulmonary Arterial Hypertension

United States, Netherlands, Canada, Belgium, France, Germany, Italy, Spain, United Kingdom, Australia, Poland, Austria, Brazil, Israel, Argentina, Mexico
VA Office of Research and Development
Medical University of South Carolina

Completed

Proteolytic Enzyme Induction Within the Human Myocardial Interstitium

Heart Disease

United States
ICOS-Texas Biotechnology
ICOS Corporation; Texas Biotechnology Corporation

Unknown

Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States, Canada
Encysive Pharmaceuticals

Completed

Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States
Pfizer

Terminated

A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple Doses

Pulmonary Arterial Hypertension

Singapore
Pfizer

Completed

Confirming The Sitaxsentan Dose In Patients Undergoing Heart Surgery (FCAD02)

Cardiac Surgery Subjects | Subjects Undergoing CABG and/or Cardiac Valve Replacement

United States
Pfizer

Terminated

Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Bulgaria, Argentina, Chile, China, Colombia, Costa Rica, Czech Republic, Dominican Republic, Guatemala, India, Malaysia, Mexico, Peru, Philippines, Romania, Russian Federation, Saudi Arabia, Serbia, Slovakia, South... and more
Pfizer

Withdrawn

Drug Interaction Between Ritonavir And Sitaxsentan

Pulmonary Arterial Hypertension
Albert Einstein College of Medicine

Completed

Sodium Bicarbonate Supplementation in Chronic Kidney Disease Evaluation of Dose Response, Safety and Beneficial Effects

Chronic Kidney Disease

United States
Gladwin, Mark, MD
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age (Nitrite)

Sedentary Lifestyle | Frailty | Aging

United States
Pfizer

Terminated

Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Romania, Ukraine
University of Edinburgh
Encysive Pharmaceuticals

Completed

Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)

Pulmonary Arterial Hypertension | Vasodilation | Vasoconstriction

United Kingdom
University of Delaware

Completed

Adverse Neurogenic Actions of Dietary Salt

Blood Pressure

United States
Pfizer

Terminated

Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Bulgaria, Argentina, Chile, China, Colombia, Czech Republic, India, Malaysia, Mexico, Peru, Romania, Russian Federation, Serbia, South Africa, Thailand, Turkey, Ukraine
Imperial College London

Completed

Propionate and Energy Homeostasis (PROEM)

Obesity

United Kingdom
Novartis Pharmaceuticals

Completed

A Study of Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (ORION-5)

Homozygous Familial Hypercholesterolemia

Hong Kong, Israel, Russian Federation, Serbia, South Africa, Taiwan, Turkey, Ukraine
Beijing Tiantan Hospital

Not yet recruiting

Reducing Edema After intraCerebral Hemorrhage

Edema Brain
Amckaus PTY LTD.

Recruiting

Aom0319 SAD Study in Healthy Subjects

Healthy Volunteers

Australia
Gladwin, Mark, MD

Withdrawn

Oral Nitrite Trial for Hypertension and Metabolic Syndrome (ONPC)

Hypertension | Metabolic Syndrome

United States
Charite University, Berlin, Germany
University Hospital, Essen; University Hospital Heidelberg; Universitätsklinikum... and other collaborators

Recruiting

Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD (Pro-Kids)

CKD (Chronic Kidney Disease) Stage 5D

Germany
University of Delaware

Recruiting

Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics

Sodium Excess

United States
Albert Einstein College of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Alkali Therapy in Chronic Kidney Disease

Chronic Kidney Disease | Metabolic Acidosis

United States
University of Iowa
American Heart Association

Completed

Dietary Nitrates and Vascular Function in Patients With Peripheral Artery Disease

Peripheral Artery Disease

United States
Wageningen University
Top Institute Food and Nutrition

Completed

The Effects of Sodium and Potassium on Blood Pressure, Vascular Function and Renal Function (KaNa)

Hypertension | Blood Pressure | Vascular Function | Renal Function

Netherlands
Medical College of Wisconsin

Not yet recruiting

Effect of Propionic Acid Supplementation on Endothelial Function

Cardiovascular Diseases | Endothelial Dysfunction
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients

Vascular Diseases | Kidney Transplant; Complications | Metabolic Acidosis

United States
Sihuan Pharmaceutical Holdings Group Ltd.

Completed

A Single Ascending Dose Pharmacology Study of Anaprazole in Healthy Chinese Subjects

Healthy Male Volunteers
University of Colorado, Boulder

Completed

Nitrite Supplementation for Improving Physiological Function in Older Adults (NITRITE)

Ageing

United States
Sulfagenix Australia Pty Ltd.

Unknown

Assessing the Safety and Bioactivity of SG1002 in Heart Failure Patients

Heart Failure
University of Aberdeen

Completed

The Effects of Inorganic Nitrate on Cardiac Muscle in Angina

Chronic Stable Angina

United Kingdom
University of Zurich
Swiss Federal Institute of Technology

Completed

Influence of Sodium Bicarbonate on Time-to-exhaustion at Critical Power in Endurance Athletes

Performance

Switzerland
Austin Health

Completed

Sodium Bicarbonate in Cardiac Surgery

Cardiac Surgery and Cardiopulmonary Bypass

Australia
Aga Khan University
Zeenat Qureshi Stroke Institute

Recruiting

Best Solution Identification to Prevent Hyperchloremia Combinations of Sodium Chloride and Sodium Acetate IV Fluids Along With Standard of Care Treatment in Acute Stroke Patients (sodium acetate)

Stroke, Acute

Pakistan
Augusta University
American Heart Association

Recruiting

Salt and HMB Study

Blood Pressure

United States
National Human Genome Research Institute (NHGRI)

Active, not recruiting

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENE-FORECAST): Sodium Intervention Trial (SIT)

Cardiovascular Disease

United States
University of Colorado, Denver

Completed

Bicarbonate Administration in CKD

Chronic Kidney Disease | Metabolic Acidosis

United States
VA Office of Research and Development

Completed

Investigations of the Optimum Serum Bicarbonate Level in Renal Disease.

Diabetes Mellitus | Chronic Renal Insufficiency

United States
University Hospital, Montpellier

Terminated

Influence of Sodium Intake on Left Ventricular-arterial Coupling

Hypertension

France
Hospital Clinic of Barcelona
Fundacio Clinic Barcelona

Completed

Sodium Tungstate in Obesity (TROTA-1)

Obesity

Spain
Tabriz University of Medical Sciences

Not yet recruiting

Safety and Efficacy of Sodium Pentaborate Pentahydrate in People With Overweight and Obesity

Overweight and Obesity

Iran, Islamic Republic of
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Clinical Trial of Sodium Nitrite for Out of Hospital Cardiac Arrest (SNOCAT)

Out-Of-Hospital Cardiac Arrest

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-C (ORION-15)

Hypercholesterolemia | Heterozygous Familial Hypercholesterolemia

Japan
AstraZeneca

Completed

A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia. (HARMONIZE Asia)

Hyperkalemia

China
Jennifer Gassman, PhD
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); The...

Completed

The BASE Study: Bicarbonate Administration to Stabilize Estimated Glomerular Filtration Rate (eGFR) (BASE)

Chronic Kidney Disease

United States

Search clinical trials for: Sitaxentan sodium/Placebo

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