Search clinical trials for: Sitaxsentan and Sildenafil

Total 269092 results

Pfizer

Terminated

A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple Doses

Pulmonary Arterial Hypertension

Singapore
Pfizer

Terminated

Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients

Hypertension, Pulmonary

Japan
Pfizer

Terminated

A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients

Hypertension, Pulmonary

Japan
Pfizer

Terminated

Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Romania, Ukraine
Pfizer

Terminated

A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients With Pulmonary Arterial Hypertension (STRIDE-3)

Pulmonary Arterial Hypertension

United States, Netherlands, Canada, Belgium, France, Germany, Italy, Spain, United Kingdom, Australia, Poland, Austria, Brazil, Israel, Argentina, Mexico
Institut National de la Santé Et de la Recherche...

Terminated

Study on the Effects of Sitaxsentan on Airway Remodeling in Patients With Severe Asthma (Sitax)

Effect of Sitaxsentan on Airway Remodeling in Severe Asthma

France
Pfizer

Terminated

A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed Thelin (PROSE)

Pulmonary Arterial Hypertension

Belgium, Germany, France
Pfizer

Terminated

Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Bulgaria, Argentina, Chile, China, Colombia, Czech Republic, India, Malaysia, Mexico, Peru, Romania, Russian Federation, Serbia, South Africa, Thailand, Turkey, Ukraine
Pfizer

Completed

Pilot Chart Review Study Of Sitaxentan Sodium (Thelin) In Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension
Pfizer

Completed

Phase 1, Single and Multiple Doses Study of Sitaxentan in Japanese and Western Subjects

Healthy

United States
Pfizer

Completed

Confirming The Sitaxsentan Dose In Patients Undergoing Heart Surgery (FCAD02)

Cardiac Surgery Subjects | Subjects Undergoing CABG and/or Cardiac Valve Replacement

United States
VA Office of Research and Development
Medical University of South Carolina

Completed

Proteolytic Enzyme Induction Within the Human Myocardial Interstitium

Heart Disease

United States
ICOS-Texas Biotechnology
ICOS Corporation; Texas Biotechnology Corporation

Unknown

Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States, Canada
Encysive Pharmaceuticals

Completed

Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States
Pfizer

Terminated

Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Bulgaria, Argentina, Chile, China, Colombia, Costa Rica, Czech Republic, Dominican Republic, Guatemala, India, Malaysia, Mexico, Peru, Philippines, Romania, Russian Federation, Saudi Arabia, Serbia, Slovakia, South... and more
Pfizer

Withdrawn

Drug Interaction Between Ritonavir And Sitaxsentan

Pulmonary Arterial Hypertension
Pfizer

Completed

A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failure

Diastolic Heart Failure

United States, Canada
University of Pennsylvania
Walter Reed National Military Medical Center

Not yet recruiting

Sildenafil for Microvasculopathy in Chronic TBI

Traumatic Brain Injury
Duke University
National Heart, Lung, and Blood Institute (NHLBI); Pfizer

Completed

Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study) (RELAX)

Heart Failure

United States, Canada
Rambam Health Care Campus

Unknown

Safety and Clinical Effectiveness of 2 Lower Dose Combined PDE5i's vs. Single Maximal Dose PDE5i

Impotence

Israel
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Versus To Viagra® Oral Tablet.

Erectile Dysfunction

Singapore
Northwestern University

Completed

Topical Sildenafil as Pre-Treatment for Hand-Foot Skin Reaction

Hand Foot Skin Reaction

United States
The Cleveland Clinic

Completed

Effect of Sildenafil on Diffusion Capacity in Patients With PH and Parenchymal Lung Disease

Pulmonary Hypertension | Diffuse Parenchymal Lung Disease

United States
West Penn Allegheny Health System
Johns Hopkins University; University of Colorado, Denver; Massachusetts General... and other collaborators

Withdrawn

Pharmacogenomics in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension | Pulmonary Hypertension | PAH WHO Group I

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Bioequivalence Study For Orally-Disintegrating Tablet Of Sildenafil

Healthy

Japan
Rigshospitalet, Denmark
Glostrup University Hospital, Copenhagen

Completed

Effect of Modulating the nNOS System on Cardiac, Muscular and Cognitive Function in Becker Muscular Dystrophy Patients

Becker Muscular Dystrophy

Denmark
University of Edinburgh
Encysive Pharmaceuticals

Completed

Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)

Pulmonary Arterial Hypertension | Vasodilation | Vasoconstriction

United Kingdom
iX Biopharma Ltd.
Linear Clinical Research

Completed

A Pivotal Study of the Bioequivalence of Oral Viagra® and a Test Sublingual Sildenafil Wafer

Erectile Dysfunction

Australia
Assiut University

Not yet recruiting

Combined On-demand Sildenafil Citrate and Tramadol Hydrochloride for Treatment of Premature Ejaculation

Premature Ejaculation
N4 Pharma UK Ltd.
BDD Pharma Ltd

Completed

Pharmacoscintigraphic Study to Evaluate Two Sildenafil Products

Erectile Dysfunction

United Kingdom
University Hospital, Grenoble

Completed

"As Required" Oral Sildenafil in Raynaud's Phenomenon (PROFIL)

Raynaud's Phenomenon

France
University Hospital, Montpellier

Withdrawn

Efficacy of Phosphodiesterase-type 5 Inhibitors in Patients With Univentricular Congenital Heart Disease (VU-INHIB)

Pulmonary Hypertension | Single-ventricle | Univentricular Heart
Bispebjerg Hospital

Completed

Motor Response to Sildenafil in PD

Erectile Dysfunction | Parkinsons Disease

Denmark
Pfizer

Completed

A Randomized, Double-Blinded, Placebo-Controlled, Two-Way Crossover Study to Investigate the Safety and Toleration of Single Dose Sildenafil in Subjects Receiving Chronic UK-369,0031

Urinary Bladder, Overactive | Prostatic Hyperplasia | Erectile Dysfunction

Singapore
Strategic Science & Technologies, LLC

Completed

Single-Dose Relative Bioavailability Study of SST-6006, a Topical Sildenafil Cream Versus Oral Sildenafil in Healthy Male Adults

Healthy

United States
Cedars-Sinai Medical Center

Completed

PDE Inhibitors in DMD Study (Acute Dosing Study)

Duchenne Muscular Dystrophy

United States
Bio-innova Co., Ltd

Not yet recruiting

Sildenafil 100 mg Tablets Relative to Viagra 100 mg Tablets

Healthy Subjects
The University of Texas Medical Branch, Galveston

Completed

Role of Skeletal Muscle Nitric Oxide Production in Age-related Fatigue and Fatigability

Fatigue | Aging

United States
National Jewish Health
Augusta University; Cystic Fibrosis Foundation

Recruiting

Sildenafil Exercise: Role of PDE5 Inhibition

Cystic Fibrosis

United States
Universidad del Norte

Not yet recruiting

Endovenous Sildenafil Early Management in Newborns Pulmonary Hypertension (HIPSEN)

Hypertension, Pulmonary
Pfizer's Upjohn has merged with Mylan to form Viatris...

No longer available

Local Open-Label Access Study For Patients Who Completed A1481244 Study In Brazil

Pulmonary Arterial Hypertension

Brazil
Montefiore Medical Center

Completed

Sildenafil To Prevent Clot (SToPClot)

Thrombosis | Hemolysis

United States
Postgraduate Institute of Medical Education and...

Unknown

To Compare the Efficacy of Combination Therapy vs Monotherapy for Pulmonary Arterial Hypertension in Systemic Sclerosis (BosSilSS)

Associated Pulmonary Arterial Hypertension

India
Hospital Universitari Vall d'Hebron Research Institute

Unknown

Effectiveness of the Vasodilator Test With Revatio, Made in Patients With Acute Pulmonary Hypertension

Pulmonary Hypertension

Spain
Milton S. Hershey Medical Center
Children's Miracle Network

Completed

The Effects of Sildenafil on Exercise Function and Capacity in Patients With Fontan Circulation

Fontan Circulation

United States
Augusta University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Blood Flow and Vascular Function in Cystic Fibrosis (CF-FLOW)

Cystic Fibrosis

United States
University of Alberta

Recruiting

The Impact of Sildenafil on the Pulmonary Circulation in Healthy Trained and Untrained Humans

Healthy

Canada
Xintian Pharmaceutical

Completed

Clinical Observation of Ningmitai Capsule in Treating Chronic Pelvic Pain Syndrome With Erectile Dysfunction

Erectile Dysfunction | Chronic Prostatitis With Chronic Pelvic Pain Syndrome

China
University Hospital, Angers

Withdrawn

Efficacy of Sildenafil on the Morbi-mortality of Peripheral Arterial Diseased Patients With Intermittent Claudication (VALSTAR)

Peripheral Arterial Occlusive Disease
Hartford Hospital

Unknown

Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer (HBOT)

Prostatic Neoplasms | Impotence

United States

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