Search clinical trials for: sodium 2,2 dimethylbutyrate

Total 11151 results

Boston University
HemaQuest Pharmaceuticals Inc.

Completed

Trial of HQK-1001 in Beta Thalassemia Intermedia in Lebanon (LB-04-THAL)

Beta Thalassemia Intermedia

Lebanon
Boston University
Mahidol University

Completed

Study of SDMB (2,2 Dimethylbutyrate, Sodium Salt) in Beta Thalassemia Intermedia in Thailand (ST20-P2T)

Beta Thalassemia Intermedia

Thailand
Rigshospitalet, Denmark

Completed

Hyperlactatemia During and After Tumorcraniotomy

Brain Tumor | Surgery | Anesthesia | Hyperlactatemia

Denmark
NovaBay Pharmaceuticals, Inc.

Completed

Study to Evaluate NVC-422 for Urinary Catheter Blockage and Encrustation

Urinary Catheter Blockage and Encrustation

United States
University of Rostock

Completed

Laryngeal Injuries After Anesthesia Induction With Three Different Sevoflurane Concentrations (Without Muscle Relaxant) (SEVODosage)

Other Specified Injuries of Vocal Cord, Sequela

Germany
Prove pharm

Completed

3,3'-Dioxo-2,2'-Bisindolylidene-5,5'-Disulfonate Disodium 0.8% Solution as an Aid for Ureteral Patency (UP)

Ureter Injury

United States
Alios Biopharma Inc.
Janssen Pharmaceutica

Terminated

First in Human Study of AL-704; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C

Chronic Hepatitits C

Georgia, Moldova, Republic of, France
Cytonet GmbH & Co. KG
CRS Clinical Research Services Mannheim GmbH

Completed

Study in Healthy Subjects, Patients With Urea Cycle Disorders (UCD) and Carriers of UCD Mutations to Evaluate Urea Cycle Function

Urea Cycle Disorders

Germany
University of Nottingham

Completed

Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.

Insulin Resistance | Age Problems

United Kingdom
University of Delaware

Completed

Adverse Neurogenic Actions of Dietary Salt

Blood Pressure

United States
Mette M Berger
Texas A&M University

Completed

Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients? (HMB-ICU-CH)

Critical Illness | Muscle Weakness

Switzerland
Seqirus
Department of Health and Human Services

Active, not recruiting

Study to Evaluate Safety and Immunogenicity of Different Priming and Booster Regimens With Adjuvanted H5N8 and/or H5N6 Influenza Vaccine in Adults

Infections | Virus Diseases | Respiratory Tract Infections | Influenza, Human | Infection Viral

United States
Boston Children's Hospital

Completed

Senicapoc and Dehydrated Stomatocytosis

Dehydrated Hereditary Stomatocytosis

United States
Metabolic Technologies Inc.
Iowa State University

Completed

Effects of HMB Supplementation on Recovery Following ACL Surgery

ACL Injury

United States
Chinese University of Hong Kong
Abbott

Recruiting

RCT of Combination Effect of Vibration Treatment and HMB Supplementation on Myosteatosis and NMJ Degeneration

Sarcopenia | Musculoskeletal Abnormalities | Connective Tissue Diseases in Old Age

Hong Kong
The University of The West Indies

Unknown

Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell Anaemia

Sickle Cell Anemia
University of Campinas, Brazil

Completed

Evaluation of Sodium Hypochlorite as a Denture Cleanser

Problems With Dentures

Brazil
Metabolic Technologies Inc.
Iowa State University; South Dakota State University

Completed

Nutritional Intervention for Age-related Muscular Function and Strength Losses

Sarcopenia | Muscle Strength

United States
University College, London
Imperial College London; Cancer Research UK; National Cancer Imaging Translational...

Recruiting

[18F]FPIA PET/CT Imaging in Patients With Solid Tumours ([18F]FPIA)

Cancer | Tumor, Solid

United Kingdom
Theraclone Sciences, Inc.

Completed

Safety Study of Human Anti-Cytomegalovirus Monoclonal Antibody

Cytomegalovirus Infections

United States
Aga Khan University
Zeenat Qureshi Stroke Institute

Recruiting

Best Solution Identification to Prevent Hyperchloremia Combinations of Sodium Chloride and Sodium Acetate IV Fluids Along With Standard of Care Treatment in Acute Stroke Patients (sodium acetate)

Stroke, Acute

Pakistan
Guy's and St Thomas' NHS Foundation Trust

Active, not recruiting

A Study to Investigate the Effect of HMB on Skeletal Muscle Wasting in Early Critical Illness (HMB-ICU)

Critical Illness

United Kingdom
University of Roma La Sapienza

Completed

Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation After Liver Transplantation (HMB)

Sarcopenia

Italy
Thallion Pharmaceuticals

Terminated

Efficacy Study of TLN-232 in Patients With Recurring Metastatic Melanoma

Melanoma

United States, Canada
Celgene

Completed

Safety and Pharmacokinetics of AVL-292 Following Multiple Doses and the Effect of Food on the Single-dose Pharmacokinetics of AVL-292

Healthy

United States
Thallion Pharmaceuticals

Completed

Phase II Study of CAP-232 in Patients With Refractory Metastatic Renal Cell Carcinoma

Carcinoma, Renal Cell

France
Arcutis Biotherapeutics, Inc.

Completed

Safety and Efficacy of ARQ-252 Cream in Subjects With Chronic Hand Eczema

Chronic Hand Eczema

United States, Australia, Canada
Poznan University of Medical Sciences
National Science Centre, Poland; Poznan University of Life Sciences

Completed

The Effect of β-hydroxy-β-methylbutyrate Supplementation on Physical Capacity and Body Composition in Trained Athletes

Supplementation | Sport | Supplements

Poland
Amgen

Completed

A First-in-Human, Double Blind, Single Dose Study in Healthy Subjects and Subjects With Mild Atopic Asthma.

Asthma

United States
Akros Pharma Inc.

Terminated

Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of JTT-252

Diabetes Mellitus

United States
Metabolic Technologies Inc.

Completed

Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness

Muscle Damage

United States
Gunkang Pharmaceuticals, Inc

Recruiting

Clinical Study to Evaluate the Efficacy and Safety of GNS-212-E in Bowel Preparation for Colonoscopy (GNS-212-E)

Colonoscopy | Bowel Preparation

Korea, Republic of
Massachusetts General Hospital

Withdrawn

Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit (STROMA-ICU)

Muscle Atrophy
Federal University of São Paulo
Cristália Produtos Químicos Farmacêuticos Ltda.

Unknown

Eutectic Mixture for Hemorrhoidectomy Postoperative (CRT054)

Hemorrhoidectomy

Brazil
Evofem Inc.
Neothetics, Inc

Terminated

Extension Study to Evaluate the Post-Treatment Safety and Duration of Clinical Effect of LIPO-202

Central Abdominal Bulging
Pontificia Universidad Catolica de Chile

Completed

Topical Anesthesia Versus Placebo to Decrease Pain in Rubber Band Ligation for Treatment of Internal Hemorrhoids

Pain | Hemorrhoids

Chile
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Targeted Treatment for RET Fusion-Positive Advanced Non-Small Cell Lung Cancer (A LUNG-MAP Treatment Trial)

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
REGENXBIO Inc.

Recruiting

AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy

United States
Alpine Immune Sciences, Inc.

Terminated

An Open-label Study of ALPN-202 in Subjects With Advanced Malignancies (NEON-1)

Lymphoma | Advanced Solid Tumor

United States, Australia
GenSpera, Inc.

Completed

Efficacy, Safety and CNS Exposure of G-202 (Mipsagargin) in Patients With Recurrent or Progressive Glioblastoma

Glioblastoma Multiforme

United States
GenSpera, Inc.

Completed

Dose-Escalation Phase 1 Study of G-202 (Mipsagargin) in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Neothetics, Inc

Unknown

An Open-Label Study to Evaluate Retreatment With LIPO-202

Central Abdominal Bulging

United States
Kyowa Kirin Co., Ltd.

Completed

A Phase 3 Study of OPC-262 in Patients With Type 2 Diabetes

Diabetes, Type 2

Japan
Metabolic Technologies Inc.

Completed

The Effects of β-Hydroxy-β-methylbutyrate Free Acid and High-Intensity Interval Training

Exercise

United States
Kartos Therapeutics, Inc.

Completed

A Phase 1 Study Evaluating AMG 232 in Advanced Solid Tumors or Multiple Myeloma

Cancer | Glioblastoma | Multiple Myeloma | Advanced Solid Tumors | Oncology | Tumors | Advanced Malignancy | Oncology Patients

United States, France, Netherlands
Devalingam Mahalingam
GenSpera, Inc.

No longer available

Continued Administration of G-202 for One Patient With Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma
GenSpera, Inc.

Withdrawn

Phase 2 Study of G-202 in Patients With Chemotherapy-Naïve Metastatic Castrate-Resistant Prostate Cancer

Prostate Cancer.

United States
Kyowa Kirin Co., Ltd.

Completed

A Study of OPC-262 in Patients With Type 2 Diabetes

Diabetes Type 2

Japan
University of Illinois at Urbana-Champaign

Completed

Efficacy of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation in Hemodialysis Patients

End Stage Renal Disease | Chronic Kidney Disease | Muscle Loss | Complication of Dialysis

United States
Immune-Onc Therapeutics
California Institute for Regenerative Medicine (CIRM)

Recruiting

IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML

CMML | AML With Monocytic Differentiation

United States

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