Search clinical trials for: Sterile Normal Saline (0.9% NaCl)

Total 5745 results

Alnylam Pharmaceuticals

Completed

A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy Subjects

Transthyretin-mediated Amyloidosis (ATTR Amyloidosis)

United Kingdom
Alnylam Pharmaceuticals
The Medicines Company

Completed

A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Hypercholesterolemia

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety, Tolerability, and Parmacokinetics of ALN-TTR02 in Healthy Volunteer Subjects

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-PCS02 in Subjects With Elevated LDL-Cholesterol (LDL-C)

Elevated LDL-Cholesterol (LDL-C)

United Kingdom
Alnylam Pharmaceuticals

Completed

Trial to Evaluate Safety and Tolerability of ALN-TTR01 in Transthyretin (TTR) Amyloidosis

Transthyretin Mediated Amyloidosis (ATTR)

United Kingdom, France, Portugal, Sweden
Arrowhead Pharmaceuticals

Completed

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Dyslipidemias | Hypertriglyceridemia | Familial Hypercholesterolemia

Australia, New Zealand
Arrowhead Pharmaceuticals

Completed

Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS)

Hypertriglyceridemia | Familial Chylomicronemia

Australia, Canada, New Zealand
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
Alnylam Pharmaceuticals

Completed

ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)

Amyloid Neuropathies | Amyloid Neuropathies, Familial | Amyloidosis, Hereditary | Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC) | Amyloidosis, Hereditary, Transthyretin-Related | Familial Transthyretin Cardiac Amyloidosis

United States, France, Italy, Spain, Canada, Germany, Belgium, Sweden, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)

Acute Intermittent Porphyria

United States, United Kingdom, Sweden
Alnylam Pharmaceuticals

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Amyloid Neuropathies | Amyloid Neuropathies, Familial | TTR-mediated Amyloidosis | Amyloidosis, Hereditary | Amyloidosis, Hereditary, Transthyretin-Related | Familial Amyloid Polyneuropathies

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Germany, France, Brazil, Turkey, Korea, Republic of, Taiwan, United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC (Revusiran) in Healthy Volunteers

TTR-mediated Amyloidosis

United Kingdom
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Arrowhead Pharmaceuticals

Completed

Study of ARO-HSD in Healthy Volunteers and Patients With Non-Alcoholic Steatohepatitis (NASH) or Suspected NASH

Non-alcoholic Steatohepatitis

New Zealand
Dicerna Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

Primary Hyperoxaluria Type 3

United States, Germany, Netherlands, United Kingdom
Arrowhead Pharmaceuticals

Completed

Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)

Hepatitis B

Australia, Hong Kong, New Zealand
Alnylam Pharmaceuticals

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of ALN-TTR02 in Japanese Healthy Volunteers

Transthyretin (TTR)-Mediated Amyloidosis

United Kingdom
University Hospital Inselspital, Berne

Completed

Hypertonic Saline for Fluid Resuscitation After Cardiac Surgery (HERACLES)

Cardiovascular Diseases | Valvular Heart Disease

Switzerland
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS APO(a)-LRx in Healthy Volunteers With Elevated Lipoprotein(a)

Elevated Lipoprotein(a)

Canada
Arrowhead Pharmaceuticals

Completed

Study of ARO-AAT in Normal Adult Volunteers

Alpha 1-Antitrypsin Deficiency

New Zealand
Alnylam Pharmaceuticals

Terminated

A Study of an Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

Antitrypsin Deficiency Liver Disease

United Kingdom
Sanofi

Completed

A Phase 1 Study of an Investigational Drug, ALN-AT3SC, in Healthy Volunteers and Hemophilia A or B Patients

Hemophilia A | Hemophilia B

Bulgaria, Switzerland, United Kingdom, United States, Russian Federation
Atox Bio Ltd
Biomedical Advanced Research and Development Authority

Completed

Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections (ACCUTE)

Necrotizing Fasciitis | Necrotizing Soft Tissue Infections | Fournier's Gangrene

United States, France
LipimetiX Development, LLC

Completed

Safety Study of AEM-28 to Treat Refractory Hypercholesterolemia

Hypercholesterolemia | Hyperlipoproteinemia Type II

Australia
University of Haifa
Western Galilee Hospital-Nahariya

Recruiting

Physiological, Cognitive, and Personal Features in the Link Between Placebo-effect and Variability of Pain Reports

Chronic Back Pain

Israel
Dicerna Pharmaceuticals, Inc.

Completed

A Study to Evaluate DCR-PHXC in Children and Adults With Primary Hyperoxaluria Type 1 and Primary Hyperoxaluria Type 2 (PHYOX2)

Kidney Diseases | Urologic Diseases | Genetic Disease | Primary Hyperoxaluria Type 1 (PH1) | Primary Hyperoxaluria Type 2 (PH2)

Poland, United Kingdom, New Zealand, United States, Australia, Canada, France, Germany, Israel, Italy, Japan, Lebanon, Netherlands, Romania, Spain
Alnylam Pharmaceuticals

Terminated

A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B | Chronic Hepatitis B | Hepatitis B, Chronic | HBV | Hepatitis B Infection

United Kingdom, New Zealand, Singapore, Korea, Republic of, Australia, Hong Kong
University Hospital, Basel, Switzerland
Fresenius AG

Completed

BaSES Trial: Basel Starch Evaluation in Sepsis (BaSES)

Sepsis | Septic Shock | Severe Sepsis

Switzerland
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis (dHACM)

Fasciitis, Plantar

United States
Universitas Bali Internasional

Completed

The Effects of Intra-articular Platelet-Rich Plasma Injection on The Severity of Knee Osteoarthritis

Osteoarthritis, Knee

Indonesia
NovaBay Pharmaceuticals, Inc.

Completed

Study to Evaluate NVC-422 for Urinary Catheter Blockage and Encrustation

Urinary Catheter Blockage and Encrustation

United States
Ahmed Mohamed ELbadawy

Unknown

Prophylaxis Versus Treatment for TURP Syndrome.

Transurethral Resection of Prostate Syndrome

Egypt
Rawalpindi Medical College

Completed

Effect of Hot Saline Irrigation on the Operative Field During Endoscopic Sinus Surgery

Rhinosinusitis

Pakistan
BioAegis Therapeutics Inc.

Not yet recruiting

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

Infections | Acute Respiratory Distress Syndrome
Larissa University Hospital

Completed

Effect of Nasopharyngeal Wash With Normal Saline on SARS-CoV2 Viral Load

SARS-CoV2 Infection

Greece
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Achille Tendonitis

Tendonitis;Achilles

United States
MiMedx Group, Inc.

Completed

Micronized dHACM Injectable for the Treatment of Plantar Fasciitis

Fasciitis, Plantar

United States
Chulalongkorn University
National Research Council of Thailand

Terminated

Randomized Controlled Study of the Effectiveness of IV Fluid Infusion in Patients With Acute Ischemic Stroke (IVIS) (IVIS)

Ischemic Stroke

Thailand
Hamilton Health Sciences Corporation

Completed

Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial

Hyponatremia | Hypernatremia

Canada
Tri-Service General Hospital

Completed

Fluid Restriction After Stapled Hemorrhoidopexy

Fluid Restriction

Taiwan
Noveome Biotherapeutics, formerly Stemnion

Completed

Safety, Efficacy and Treatment Regimen Study of ST266 in Subjects With Moderate to Severe Periodontitis

Periodontal Disease

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Candidate Clostridium Difficile Toxoid Vaccine in Healthy Adult Subjects Aged 40 to 75 Years in Japan

Clostridium Difficile Infection

Japan
University Hospital, Basel, Switzerland

Completed

Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues (SKIP)

Smoking Cessation | Craving | Weight Change, Body | Glucagon-like Peptide-1

Switzerland
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Brain Ketone Metabolism in Type 1 Diabetes

Hypoglycemia | Type 1 Diabetes

United States
Vasopharm GmbH

Completed

Phase 2 a Study to Assess Safety and Pharmacokinetics of VAS203 in Patients With Traumatic Brain Injury (NOSTRA)

Traumatic Brain Injury

Austria, France, Spain, Switzerland, United Kingdom
Meshalkin Research Institute of Pathology of Circulation

Completed

The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients. (ESHHS)

Coronary Artery Disease | Edema

Russian Federation
Biogen

Completed

Long-Term Assessment of Remyelinating Therapy (RENEWED)

Acute Optic Neuritis

Sweden, Spain, United Kingdom, Germany, Canada, Denmark, Hungary, Belgium, Czechia, Australia, Italy
First Affiliated Hospital Xi'an Jiaotong University
Xijing Hospital; Shaanxi Provincial People's Hospital; Second Affiliated Hospital... and other collaborators

Unknown

Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental Outcome

Cerebral Palsy | Intracranial Hemorrhages | Premature Infants | Periventricular Leukomalacia

China
Vac4All
University of Bamako

Completed

Proof-of-Concept Study of MSP3-LSP Vaccine to Protect Against Malaria in Africa (MSP3-POC)

Malaria

Mali
University of Sydney
National Health and Medical Research Council, Australia

Active, not recruiting

PAEAN - Erythropoietin for Hypoxic Ischaemic Encephalopathy in Newborns (PAEAN)

Hypoxic-Ischemic Encephalopathy

Australia, Singapore, New Zealand

Search clinical trials for: Sterile Normal Saline (0.9% NaCl)

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