Search clinical trials for: Sustiva® (efavirenz)

Total 14161 results

University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Johns Hopkins University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Pharmacokinetic Interaction Study of Efavirenz and American Ginseng in Healthy Volunteers

Healthy Volunteers

United States
St Stephens Aids Trust

Completed

PK of Tenofovir, Emtricitabine and Efavirenz in Healthy Volunteers

HIV Infections | HIV Infection

United Kingdom
University of Minnesota

Completed

Sustiva Levels With Use of a Gel Capsule

HIV Infections | HIV

United States
St Stephens Aids Trust
University of Liverpool

Suspended

PK of Efavirenz & Lopinavir Nano-formulations in Healthy Volunteers

HIV

United Kingdom
Stanford University

Terminated

A Study to Determine the Best Dose of Antivirals in Patients With Both TB and HIV (OPTI-NNRTI)

HIV Infections | Tuberculosis

Brazil
Oswaldo Cruz Foundation
Ministry of Health, Brazil

Terminated

Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg (IPEC-EFV)

HIV Infections | Tuberculosis

Brazil
Gilead Sciences

Completed

Study of Treatment of Antiretroviral-naive, HIV-1-Infected Patients Comparing Tenofovir Disoproxil Fumarate Administered in Combination With Lamivudine and Efavirenz vs. Stavudine, Lamivudine and Efavirenz.

HIV Infections
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety and Antiretroviral Activity of MK-0518 Versus Efavirenz in Treatment Naive HIV-Infected Patients, Each in Combination With TRUVADA (0518-021 EXT)

HIV Infections
National Institute of Allergy and Infectious Diseases...

Completed

Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteers

HIV | Tuberculosis

United States
Abbott

Completed

A Simplified Kaletra® (Lopinavir/Ritonavir)-Based Therapy Versus a Sustiva® (Efavirenz)-Based Standard of Care in Previously Non-Treated HIV-Infected Subjects

HIV Infections

United States
St Stephens Aids Trust
ViiV Healthcare

Unknown

Efavirenz to Dolutegravir Switch in Patients With CNS Toxicity

HIV

United Kingdom
PENTA Foundation
Medical Research Council; ANRS, Emerging Infectious Diseases

Unknown

BREATHER (PENTA 16) Short-Cycle Therapy (SCT) (5 Days on/2 Days Off) in Young People With Chronic HIV-infection (BREATHER)

HIV

United Kingdom, Uganda, Ireland, United States, France, Germany, Thailand, Ukraine
Germans Trias i Pujol Hospital

Completed

Modification of Doses of Efavirenz According to Its Blood Concentration in HIV Patients

HIV

Spain
Bamrasnaradura Infectious Diseases Institute
Thai Red Cross AIDS Research Centre; Clinical Research Collaborative Network

Completed

Effectiveness of Efavirenz-based Regimen in HIV-1-infected Patients With Nevirapine Hypersensitivity

Treatment Failure, HIV or AIDS | CD4 Cell Counts

Thailand
Zai Lab (Shanghai) Co., Ltd.
Mirati Therapeutics Inc.

Active, not recruiting

The Clinical Trial to Evaluate the Pharmacokinetics and Safety of MRTX849 in Patients With Advanced Solid Tumors

Advanced or Metastatic Solid Tumor

China
Georgetown University
GlaxoSmithKline

Completed

A Study in Underrepresented Patient Population or Regimen Tolerability: SUPPoRT (SUPPoRT)

Human Immunodeficiency Virus Infections

United States
Bristol-Myers Squibb

Terminated

Safety, Efficacy and Dose-response Study of BMS-986001 in Subjects With HIV-1 Infection Who Are Treatment-naive

HIV-1 Infection

Thailand, United States, Australia, Canada, Spain, Colombia, South Africa, Hungary, France, Peru, Argentina, Chile, Mexico
Yunnan AIDS Care Center

Unknown

Safety and Efficacy of Raltegravir+TDF+3TC in HBV/HIV Co-infected Patients

HIV Infections | HBV Coinfection

China
Bristol-Myers Squibb

Completed

Pharmacokinetics of Efavirenz in HIV-1 Infected Subjects With Hepatic Impairment

HIV Infections | Hepatic Impairment

United States, Italy
Vanderbilt University

Completed

Genetic Determinants of the Metabolism of Non-nucleoside Reverse Transcriptase Inhibitors

HIV Infections
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la...

Completed

Antiretroviral Treatment Simplification Study With Efavirenz + Abacavir + 3TC Once Daily

HIV Infections

Spain
University of California, San Francisco
Makerere University; Infectious Diseases Research Collaboration, Uganda; Makerere...

Completed

Early HIV Therapy in Patients With High CD4 Cell Counts (EARLI)

HIV

Uganda
Bristol-Myers Squibb

Completed

Study to Determine the Effect of Efavirenz on the ECG QTcF Interval in Healthy Subjects

HIV/AIDS

United States
Gilead Sciences

Completed

ROCKET I - Randomized Open Label Switch for Cholesterol Elevation on Kivexa Evaluation Trial (ROCKET I)

HIV Infections

United Kingdom
Parc de Salut Mar

Terminated

Cannabis Effects on Electroencephalography (CEG)

Healthy Volunteers

Spain
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Cryptococcal Optimal ART Timing Trial (COAT)

HIV Infections | AIDS | Cryptococcal Meningitis

Uganda, South Africa
University of California, Davis

Completed

Pilot Project of Virologic and Immunologic Correlates of GALT Immune Reconstitution Following Raltegravir Therapy

HIV Infections | AIDS

United States
Mutual Pharmaceutical Company, Inc.

Completed

A Drug-Drug Interaction Study Between Fenofibric Acid and Efavirenz

Healthy

United States
French National Agency for Research on AIDS and...

Completed

Efficacy of Tenofovir-Emtricitabine and Efavirenz in HIV Infected Patients With Tuberculosis (ANRS129)

HIV Infections | Tuberculosis

France
Institut Bergonié

Completed

Phase I Dose Escalation Trial of Efavirenz in Solid Tumours or Non-Hodgkin Lymphoma in Therapeutic Failure. (ESCALE)

Non-Hodgkin's Lymphoma | Solid Tumors

France
St Stephens Aids Trust

Completed

PK Switch Efavirenz to Maraviroc in Patients Initially Suppressed on an Efavirenz-containing Regimen (SSAT033)

HIV Infection

United Kingdom
Bristol-Myers Squibb

Completed

Safety, Tolerability and Pharmacokinetics of Efavirenz in HIV-Infected Children

HIV Infections

Thailand, Mexico, Argentina, Colombia, Panama, South Africa
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

GSK1349572 Drug Interaction Study With Efavirenz

Infections, Human Immunodeficiency Virus and Herpesviridae

United States
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety and Effectiveness of Emtricitabine, Efavirenz, and Didanosine in HIV Infected Children Who Have Taken Few or No Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Case Western Reserve University
Massachusetts General Hospital; University Hospitals Cleveland Medical Center

Completed

Efavirenz for Patients With Alzheimer's Disease (EPAD)

Alzheimer Disease, Early Onset

United States
Johns Hopkins University
American College of Obstetricians and Gynecologists; The Campbell Foundation

Terminated

Pharmacokinetics and Pharmacodynamics of the Etonogestrel Contraceptive Implant When Co-administered With Efavirenz

Drug Interaction

United States
University of Nebraska

Completed

EFV Pharmacokinetics & Pharmacogenomics in Older HIV-infected Patients (EFV)

HIV Infection

United States
Indiana University

Completed

Effects of CYP2B6 Genetic Polymorphisms on Efavirenz Pharmacokinetics

HIV

United States
Bristol-Myers Squibb

Completed

A Pilot Study of Atazanavir/Ritonavir/Efavirenz as a Nucleoside Sparing Regimen

HIV Infections

United States
Samsung Medical Center

Completed

The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing One-lung Ventilation for Lung Surgery

Lung Cancer | One Lung Ventilation | Gas Exchange | Inverse-ratio Ventilation

Korea, Republic of
Bristol-Myers Squibb

No longer available

An Expanded Access Study of Oral Liquid Efavirenz in the Treatment of Children With HIV Infection

HIV Infection

United States, Puerto Rico
Gilead Sciences

Completed

Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients.

Hepatitis C | HIV

Puerto Rico
The Cleveland Clinic
Bristol-Myers Squibb; National Institute of Allergy and Infectious Diseases... and other collaborators

Terminated

Switching From Efavirenz to Atazanavir/ Ritonavir in HIV-infected Subjects With Good Virologic Suppression

HIV Infection | Mitochondrial Dysfunction

United States
University of California, San Diego
National Institute of Mental Health (NIMH); Peking University; Beijing YouAn... and other collaborators

Completed

Clinical Trial of Brain-Penetrating HIV Drugs to Prevent Cognitive Impairment in China

HIV Infections | Central Nervous System Diseases | Dementia

China
Bristol-Myers Squibb

Completed

Dose Finding Confirmation of Atazanavir With Ritonavir and Efavirenz (ATV/RTV + EFV) in Healthy Subjects

HIV Infections | Protease Inhibitor

United States
UPECLIN HC FM Botucatu Unesp

Unknown

Lopinavir/Ritonavir or Efavirenz as First-line Antiretroviral Therapy

HIV Infections

Brazil
Bristol-Myers Squibb

Completed

Study Switching HIV-1 Infected Patients With an Undetectable Viral Load on a First Protease Inhibitor-Based Regimen to an Efavirenz-Based Regimen

HIV Infections

United States, Puerto Rico
Bristol-Myers Squibb

No longer available

An Expanded Access Study of Oral Liquid Efavirenz in the Treatment of Children With HIV Infection: Canada

HIV Infection

Canada
Columbia University

Completed

Effect of Dolutegravir on Etonogestrel Levels in HIV-infected Women in Botswana

HIV Infections | Contraceptive Usage | Drug Interaction

Botswana

Search clinical trials for: Sustiva® (efavirenz)

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Armenia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations