Search clinical trials for: TAS-102

Total 9134 results

Taiho Oncology, Inc.

Completed

Study Comparing the Pharmacokinetics of FTD as a Component of TAS-102 With FTD Alone

Advanced Solid Tumors

United States
University of Oxford

Completed

A BCG Challenge Model Study to Assess Anti-mycobacterial Immunity Induced by BCG and a Candidate TB Vaccine, MVA85A

Tuberculosis

United Kingdom
University of Dundee

Recruiting

Single Palatal Temporary Anchorage Device for Anterior Open Bite (SPaTAR)

Anterior Openbite

United Kingdom
US Department of Veterans Affairs

Completed

Fitness and Daily Function in Adults

Cardiovascular Disease

United States
Aldeyra Therapeutics, Inc.
ORA, Inc.

Completed

A Study of ADX-102 in Subjects With Allergic Conjunctivitis

Conjunctivitis, Allergic

United States
Takeda

Completed

A Phase I/II Study for the Safety and Efficacy of Panitumumab in Combination With TAS-102 for Patients With Colorectal Cancer (APOLLON)

Colorectal Cancer

Japan
Mayo Clinic
National Comprehensive Cancer Network

Completed

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Stage III Gallbladder Cancer AJCC v8 | Stage IIIA Gallbladder Cancer AJCC v8 | Stage IIIB Gallbladder Cancer AJCC v8 | Refractory Gallbladder Carcinoma | Stage IV Gallbladder Cancer AJCC v8 | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder... and other conditions

United States
Takeda
COUR Pharmaceutical Development Company, Inc.

Completed

Study of the Safety, Tolerability and Pharmacokinetics of TIMP-GLIA in Subjects With Celiac Disease

Celiac Disease

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

TAS-102 and Radiation Therapy in Treating Patients With Rectal Cancer That Is Locally Recurrent, Metastatic, or Cannot Be Removed by Surgery

Recurrent Rectal Carcinoma | Rectal Adenocarcinoma | Stage IV Rectal Cancer AJCC v7 | Stage IVA Rectal Cancer AJCC v7 | Stage IVB Rectal Cancer AJCC v7

United States
Humanitas Clinical and Research Center

Unknown

Radial Versus Femoral Access for Superselective Embolization of Hepatocellular Carcinoma

Hepatocellular Carcinoma | Hepatocellular Carcinoma Non-resectable

Italy
University College, London

Not yet recruiting

Trial of Lu-177 DOTATATE (Lutathera®) in Unlicensed Indications

Medullary Thyroid Carcinoma | Bronchial and Thymic Neuroendocrine Tumour | Paraganglioma/ Phaeochromocytoma | Those Requiring Repeat Peptide Receptor Radionuclide Therapy
Wuhan Union Hospital, China

Recruiting

Safety of Cetuximab and Trifluridin Tipiracil as the Third-line Therapy in the RASwt mCRC

Colorectal Neoplasms Malignant

China
AHS Cancer Control Alberta
Tom Baker Cancer Centre

Withdrawn

A Study of Trifluridine/Tipiracil in Triple Negative Metastatic Breast Cancer (TACTIC)

Metastatic Triple Negative Breast Cancer

Canada
University of Iceland
Uppsala University

Recruiting

The Lóa Study: A Brief Digital Intervention for Women With Intrusive Memories in the SAGA Cohort

Intrusive Memories of Traumatic Event(s)

Iceland
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

Regorafenib Plus FOLFIRI With Irinotecan Dose Escalated in Patients With Previously Treated Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

Taiwan
M.D. Anderson Cancer Center
Taiho

Recruiting

TAS-102 in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

Colorectal Cancer

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; Taiho Pharmaceutical Co., Ltd.

Recruiting

TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer

Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Rectal Adenocarcinoma | Stage IIA Rectal Cancer AJCC v8 | Stage IIB Rectal Cancer AJCC v8

United States
Massachusetts General Hospital
Taiho Oncology, Inc.

Recruiting

Study of TAS-102 Plus Radiation Therapy for the Treatment of the Liver in Patients With Hepatic Metastases From Colorectal Cancer

Colorectal Cancer

United States
Hellenic Study Group of Psychoneuroimmunology in...
Servier

Completed

A Study of Trifluridine/ Tipiracil in Chemorefractory mCRC in Greece (RETRO-TAS)

Metastatic Colorectal Cancer

Greece
Fudan University

Recruiting

Regorafenib Combined With TAS-102 Versus Regorafenib Monotherapy in Third or Later Line Therapy of mCRC

Metastatic Colorectal Cancer

China
Southeast University, China

Recruiting

Comparison of Epithelial Lining Fluid and Blood Pharmacokinetics and Pharmacodynamics of Intravenous and Intravenous Plus Nebulized Polymyxin B in Multidrug Resistant Bacteria Ventilator-associated Pneumonia Patients

Ventilator-associated Pneumonia | Multidrug Resistant Bacterial Infection | Polymyxin B | Pharmacogenomic Drug Interaction

China
Tianjin Medical University Cancer Institute and...

Recruiting

Trifluridine/Tipiracil Combined With Oxaliplatin and Bevacizumab Versus XELOX Plus Bevacizumab in mCRC (TOBACO)

Advanced Colorectal Cancer | First-line Treatment

China
Baylor Research Institute
Taiho Oncology, Inc.

Recruiting

TAS-102 in Extrapulmonary Neuroendocrine Carcinoma (TAS-102 NEC)

High-grade Extra Pulmonary Neuroendocrine Cancer

United States
Taiho Pharmaceutical Co., Ltd.

Completed

A Mass Balance Study of [14C] TAS-303 in Healthy Adult Male Subjects

Healthy Male Subjects

Japan
Taiho Pharmaceutical Co., Ltd.

Completed

Mass Balance Study of [14C] TAS-205 in Healthy Volunteers

Healthy Male Subjects

Japan
Symphogen A/S

Withdrawn

Sym004 Versus TAS-102 in Patients With mCRC

Carcinoma | Metastatic Colorectal Cancer | Colorectal Cancer Metastatic
Merck Sharp & Dohme LLC

Completed

A Two-part Study of the Effects of MK-1029 in Allergen-Challenged Asthmatics (MK-1029-003)

Asthma
Takeda

Active, not recruiting

Dose-Ranging Study of the Efficacy and Safety of TAK-101 for Prevention of Gluten-Specific T Cell Activation in Participants With Celiac Disease on a Gluten-Free Diet

Celiac Disease

United States, Canada
Takeda

Completed

Single-Dose Phase 1 Study of TAK-792

Healthy Male Adults Participants

Japan
Roswell Park Cancer Institute
Pfizer

Recruiting

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

Advanced Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Clinical Stage III... and other conditions

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

A Real-world Study of Trifluridine/Tipiracil Containing Regimen for the Treatment of Patients With mCRC (REFLECT Study)

Metastatic Colorectal Cancer
University of Wisconsin, Madison
Taiho Pharmaceutical Co., Ltd.

Terminated

Safety of TAS-102 in Combination With Temozolomide for Metastatic Pancreatic NETs

Neoplasms | Cancer | Neuroendocrine Tumors | Tumors

United States
PharmaEngine

Completed

Nanoliposomal Irinotecan (Nal-IRI, ONIVYDE®) in Combination With TAS-102 (LONSURF®) in Refractory Solid Tumors

Refractory Solid Tumors

Taiwan
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Irinotecan, TAS-102 Plus Bevacizumab as a Second-Line Therapy in mCRC Patients

Metastatic Colorectal Cancer

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

Bioequivalence Study of Trifluridine and Tipiracil Tablets in Colorectal Cancer Patients

Colorectal Cancer

China
Wuhan Union Hospital, China

Recruiting

Fruquintinib in the Cross-line Treatment of Refractory mCRC

Metastatic Colorectal Cancer | Fruquintinib

China
Akdeniz University

Completed

Pain Management in Laparoscopic Living-donor Nephrectomy: The Impact of Erector Spinae Plane Block (ESPB) on Perioperative Period

Pain, Postoperative | Donor Site Complication

Turkey
Chong Kun Dang Pharmaceutical

Completed

Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-393 in Healthy Subjects

Diabetes Mellitus, Type 2

Korea, Republic of
National University Hospital, Singapore

Recruiting

Phase II Study of FTD/TPI (Lonsurf) in Metastatic Breast Cancers With or Without Prior Exposure to Fluoropyrimidines (LONBRECA)

Breast Cancer

Singapore
Taiho Oncology, Inc.

Completed

A Study Evaluating TAS-102 Plus Nivolumab in Patients With MSS CRC

Refractory Metastatic Colorectal Cancer

United States
Otsuka Pharmaceutical Co., Ltd.

Completed

A Phase 1 Study of OCV-C02 in Patients With Advanced or Relapsed Colorectal Cancer

Colorectal Cancer

Japan
Nektar Therapeutics

Completed

An Extension Study of NKTR-102 in Cancer Patients Previously Enrolled in NKTR-102 Studies

Malignant Solid Tumor

United States, Belgium
Sun Yat-sen University

Not yet recruiting

Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy (TASLARC)

Rectal Cancer

China
University of California, Irvine

Active, not recruiting

Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy

Colorectal Cancer | Metastatic Cancer | Colorectal Carcinoma | CRC

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
Georgetown University

Terminated

Ph 2 Study of TAS-102 / Bevacizumab Maintenance Therapy Post Induction Chemotherapy in Metastatic Colorectal Cancer (ALEXANDRIA)

Metastatic Colorectal Cancer

United States
Genuine Research Center, Egypt
Bio Med for Pharmaceuticals Industries (BIOMED), Egypt

Completed

Bioequivalence Study of Flibanserin From AphroFemine 100 mg F.C.T (Bio Med for Pharmaceuticals Industries (BIOMED), Egypt) Versus Addyi 100 mg Tablets (Sprout Pharmaceuticals, Inc., USA)

Healthy

Egypt
Asklepios Biopharmaceutical, Inc.

Recruiting

Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure (GenePHIT)

Congestive Heart Failure

United States
Taiho Oncology, Inc.

Terminated

TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations

Advanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating Mutations

United States, United Kingdom, Austria, France
Taiho Oncology, Inc.

Terminated

An Investigation of TAS-119 Monotherapy

Advanced Solid Tumors

Italy, Spain, United States, Netherlands, United Kingdom

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