Search clinical trials for: TBPM-PI-HBr

Total 1324 results

Spero Therapeutics
Covance

Completed

Study of the Absorption, Metabolism, and Excretion of [14C]-Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
Spero Therapeutics
Clinartis

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Healthy Volunteers

United States
Spero Therapeutics

Completed

Phase 1 Study of PK and Safety of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Subjects With Various Degrees Of Renal Function

Renal Impairment

United States
Spero Therapeutics

Completed

Bioequivalence Study Comparing Two Tablet Formulations of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
Spero Therapeutics

Completed

A Study to Compare Two Bioanalytical Assays for Tebipenem

Healthy Volunteers

United States
Spero Therapeutics
Celerion

Completed

A Single-Dose, Randomized, Placebo- and Active-Control, Four-Way, Cross-Over Study for the Evaluation of the Effect of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) on the QT/QTc Intervals in Adult Healthy Subjects

TQT Study

United States
Consorci d'Atenció Primària de Salut de l'Eixample
Instituto de Salud Carlos III

Completed

Validity of 1BPM for Diagnosis of Hypertension

Hypertension

Spain
Spero Therapeutics
Iqvia Pty Ltd

Completed

Effect of Tebipenem on Normal Human Intestinal Microbiota

Healthy Volunteers

Sweden
Spero Therapeutics

Completed

Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (ADAPT-PO)

Acute Pyelonephritis | Complicated Urinary Tract Infection

Bulgaria, Georgia, United States, Czechia, Estonia, Hungary, Latvia, Moldova, Republic of, Poland, Romania, Russian Federation, Serbia, Slovakia, South Africa, Ukraine
Waid City Hospital, Zurich

Recruiting

Prevalence of Masked Hypertension in Nephrological Patients

Masked Hypertension

Switzerland
Hippocration General Hospital
National and Kapodistrian University of Athens; Biomedical Research Foundation...

Recruiting

The Predictive Role of Proteomics in Blood Pressure Response of Hypertensive Patients Undergoing Renal Denervation. (PREDICT-RDN)

Hypertension | Proteomics | Renal Denervation

Greece
GlaxoSmithKline

Active, not recruiting

Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection

Hepatitis B, Chronic

Taiwan, Belgium, Thailand, Germany, Spain, Hong Kong, United Kingdom, France, Poland
University of Vigo
University of California, Los Angeles; National Institute on Minority Health... and other collaborators

Recruiting

Sleep-time Blood Pressure and Risk of CKD Progression (SLEEP-BP-CKD)

Chronic Kidney Diseases

Spain
Spero Therapeutics

Completed

Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
Spero Therapeutics
GlaxoSmithKline

Recruiting

A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (PIVOT-PO)

Urinary Tract Infection | Acute Pyelonephritis

Moldova, Republic of, Georgia, United States, Serbia, Bulgaria, Romania, South Africa
University Tunis El Manar

Unknown

Uterine Artery Pulsatility Index and Materno Fetal Outcomes (UADLAB)

Labor Complication

Tunisia
Peking University Third Hospital

Completed

Relationship Between Spinopelvic Parameters and Clinical Symptoms of Low-grade Lumbar Isthmic Spondylolisthesis

Isthmic Spondylolisthesis

China
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

Study of PI-88 in Patients With Advanced Melanoma

Melanoma

United States
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

PI-88 in Hepatocellular Carcinoma After Hepatectomy

Carcinoma, Hepatocellular

Taiwan
University of Michigan

Completed

The "Open Wound Bone Augmentation Concept" With Amnion-Chorion Membrane

Horizontal Ridge Deficiency

United States
Oslo University Hospital

Completed

A Multi-disciplinary Pain Intervention (MUD-PI) for Patients With Chronic Widespread Primary Pain (MUD-PI)

Chronic Pain, Widespread
Amgen

Completed

FIRST - Study of Pegfilgrastim Administered in the First and Subsequent Cycles of Myelosuppressive Chemotherapy

Neutropenia
Peptimmune

Completed

Safety Study of PI-0824 to Treat Pemphigus Vulgaris

Pemphigus Vulgaris

United States
Dayton Children's Hospital
United States Department of Defense; Kettering Health Network

Terminated

An Evaluation of Hyperbaric Treatments for Children With Cerebral Palsy

Cerebral Palsy | Cerebral Palsy, Spastic

United States
Life Molecular Imaging Ltd

Recruiting

[18F]PI-2620 Phase 3 Histopathological Study

Alzheimer Disease

United States
Life Molecular Imaging SA
Walter Reed National Military Medical Center

Active, not recruiting

Imaging [18F]PI-2620 and [18F]Florbetaben in Military Service Members With Blast Related Mild Traumatic Brain Injury

Mild Traumatic Brain Injury

United States
Assiut University

Recruiting

Perfusion Index in Assessment of Postoperative Pain in Children.

Postoperative Pain

Egypt
American Academy of Pediatrics
University of North Carolina, Chapel Hill; Thrasher Research Fund; RTI International and other collaborators

Completed

Newborn Heart Rate as a Catalyst for Improved Survival

Stillbirth | Neonatal Resuscitation | Neonatal Respiratory Depression | Neonatal Bradycardia

Congo, The Democratic Republic of the
Asan Medical Center
Korea Health Industry Development Institute

Completed

Evaluation of [18F]PI-2620 as a Potential Positron Emission Computed Tomography Radioligand for Imaging Tau Protein in the Brain

Parkinson Disease | Alzheimer Disease | Healthy Volunteer | Frontotemporal Dementia

Korea, Republic of
Jae Seung Kim

Completed

Longitudinal Changes of [18F]PI-2620 Positron Emission Tomography in Subjects With Cognitively Normal, Mild Cognitive Impairment and Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment | Cognitively Normal

Korea, Republic of
Minia University

Recruiting

AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification

Glaucoma, Angle-Closure

Egypt
University of Pennsylvania
Yale University

Recruiting

Tau PET Imaging in Opioid Use Disorder

Opioid-Related Disorders

United States
Cellxpert Biotechnology Corp.
Medigen Biotechnology Corporation

Completed

PI-88 in Treating Patients With an Advanced Malignancy (Cancer) or Stage IV Melanoma

Unspecified Adult Solid Tumor, Protocol Specific | Melanoma (Skin)

Australia, United States
Macquarie University, Australia
Life Molecular Imaging GmbH; Omniscient Neurotechnology

Active, not recruiting

Tau And Connectomics In TES Study (TACIT)

Neurodegenerative Diseases | Cognitive Impairment | Head Injury Trauma | Chronic Traumatic Encephalopathy | Traumatic Encephalopathy

Australia
XuanwuH 2
Beijing Normal University

Completed

Transcranial Photobiomodulation Intervention for Healthy Older Adults

Working Memory | Intervention | Healthy Older Adults | Functional Near-infrared Spectroscopy | Transcranial Photobiomodulation

China
University Hospital, Grenoble
Commissariat A L'energie Atomique; Fonds de Dotation Clinatec

Recruiting

Effect of Transcranial Near InfraRed Light On Cerebral Function in Young and Healthy Older Subjects: a fMRI Study (TIROC) (TIROC)

Healthy Volunteers

France
Chonbuk National University Hospital

Completed

Efficacy and Safety of Nokyong Mixture Extract(CME-PI) on Promotion of Immunity

Immunity

Korea, Republic of
Massachusetts General Hospital

Recruiting

Transcranial Photobiomodulation With Near-Infrared Light for Language in Individuals With Down Syndrome (TransPhoM-DS)

Down Syndrome

United States
University of California, San Francisco
Patient-Centered Outcomes Research Institute

Completed

The PCORnet Blood Pressure Home Monitoring Study (BP Home)

Hypertension

United States
St. Jude Children's Research Hospital

Recruiting

Use of Transcranial Photobiomodulation to Improve Cognition and Self-Reported Outcomes in Survivors of Childhood Cancer

Cancer | Hodgkin Lymphoma | Survivorship | ALL

United States
University of Colorado, Denver
American College of Radiology

Completed

Preclinical Imaging Biomarkers of Alzheimer's Disease Neuropathology in Young Adults With Youth-onset Diabetes: a Proof-of-concept Study

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Diabetes, Youth Onset

United States
Michael J. Fox Foundation for Parkinson's Research
Institute for Neurodegenerative Disorders

Completed

PPMI Tau PET Imaging

Parkinson Disease

United States
University of North Texas Health Science Center

Enrolling by invitation

Health and Aging Brain Study: Health Disparities Tau Positron Emission Tomography (PET) Scan Study

Alzheimer Disease

United States
Galenic Research Institute Ltd

Completed

Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT (OTMA-RII)

Peritoneal Neoplasms | Ascites | Yin Deficiency | Yang Deficiency

China
NYU Langone Health
National Institutes of Health (NIH); Alzheimer's Association; LiteCure LLC

Recruiting

Transcranial Photobiomodulation for Alzheimer's Disease (TRAP-AD)

Alzheimer Disease | Mild Cognitive Impairment

United States
Amgen

Completed

Pegfilgrastim Given Same Day As or Day After Carboplatin and Docetaxel in Advanced Metastatic Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer | Lung Cancer
Genentech, Inc.

Completed

Evaluation Comparing Tau PET Radiotracers, [18F]GTP1 and [18F]PI-2620 or [18F]MK-6240 in Subjects With Normal Cognition or Prodromal to Moderate Alzheimer's Disease

Alzheimer Disease (AD)

United States
Progen Pharmaceuticals

Terminated

Phase III Study of PI-88 in Post-resection Hepatocellular Carcinoma (PATHWAY)

Cancer | Hepatocellular Carcinoma | Primary Liver Cancer | Liver Cancer | Hepatoma

Hong Kong, Singapore, United States, Australia, Canada, Italy, Malaysia, Spain, Taiwan, Thailand
Amgen

Completed

Evaluating Pegfilgrastim and a Multi-Day Topotecan Regimen in Subjects With Relapsed or Refractory Ovarian Cancer

Ovarian Cancer
Uppsala University
Wellsense USA Inc.

Completed

Reduced Pressure for Less Pressure Ulcers

Pressure Ulcer

Sweden

Search clinical trials for: TBPM-PI-HBr

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Macedonia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations