Search clinical trials for: Tedizolid phosphate

Total 3669 results

Trius Therapeutics LLC

Completed

A Phase 1, Open-Label, 10 Day Safety Study

Healthy Subjects

United States
Merck Sharp & Dohme LLC

Completed

A Pharmacokinetic Study of Tedizolid Phosphate in Pediatric Participants With Gram-Positive Infections (MK-1986-014)

Gram-Positive Infections

United States, Bulgaria, Colombia, Norway, United Kingdom
Merck Sharp & Dohme LLC

Completed

A Study of Oral and Intravenous (IV) Tedizolid Phosphate in Hospitalized Participants, Ages 2 to <12 Years, With Confirmed or Suspected Bacterial Infection (MK-1986-013)

Gram-Positive Bacterial Infections
Lundquist Institute for Biomedical Innovation at...

Completed

Tolerability, Safety, and Efficacy of Tedizolid as Oral Treatment for Bone and Joint Infections (OTTER)

Bone and Joint Infection

United States
Amit.Pai
Merck Sharp & Dohme LLC

Completed

Single Dose PK of IV Tedizolid Phosphate in Morbidly Obese and Non-Obese Adults

Obesity
Bayer

Completed

Safety and Efficacy of BAY1192631 in Japanese Patients With Methicillin-resistant Staphylococcus Aureus (MRSA) Infections

Skin Diseases, Infectious

Japan
Trius Therapeutics LLC

Completed

A Phase 1 Crossover Study of Blood Pressure and Heart Rate Response

Healthy Subjects

United States
Trius Therapeutics LLC

Completed

TR-701 FA vs. Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections. (ABSSSI)

Skin and Subcutaneous Tissue Bacterial Infections

United States, Argentina, Brazil, Canada, Czechia, Germany, Hungary, Latvia, Peru, Slovakia, Ukraine
Bayer

Terminated

Sivextro in Acute Bacterial Skin and Skin Structure Infection (ABSSSI) in Hospitalized Patients. A Global Observational Study (DART)

Skin Disease, Infectious

Russian Federation, Mexico, Singapore
Trius Therapeutics LLC

Completed

Ascending Dose Pharmacokinetic (PK) and Absolute Bioavailability (BA) (IV/SAD/MAD)

Bacterial Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018)

Acute Bacterial Skin and Skin Structure Infections

United States, Brazil, Bulgaria, Georgia, Germany, Guatemala, Latvia, Lithuania, Mexico, Poland, Russian Federation, South Africa, Turkey, Ukraine
Trius Therapeutics LLC

Completed

Exploratory Pharmacokinetic and Bioavailability Study of 2 Capsule Formulations of Torezolid Phosphate

Healthy

United States
Trius Therapeutics LLC

Completed

Pulmonary Disposition of TR-700 Following Once-Daily Oral 200 mg

Bacterial Infection

United States
Trius Therapeutics LLC

Completed

Food Effects of Single Oral Dose of 600mg TR-701

Healthy

United States
Trius Therapeutics LLC

Completed

Pharmacokinetic (PK) Study of Oral and IV TR-701 FA in Adolescent Patients

Bacterial Infection
Trius Therapeutics LLC

Completed

A Phase 1 TR-701 FA Study of Blood Pressure Response Post Tyramine Challenge

Healthy Volunteers

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB) (TEDITUB)

Tuberculosis | Multidrug Resistant Tuberculosis

France
Trius Therapeutics LLC

Completed

A PK and Safety Study in Subjects With Hepatic Impairment

Hepatic Impairment

United States
Fundacion Clinic per a la Recerca Biomédica

Unknown

Efficacy and Tolerance of 4 Weeks of Tedizolid in Prosthetic Joint Infections Treated With Implant Removal (PROTEDI)

Prostheses Infection
Dong-A ST Co., Ltd.

Completed

Phase I Clinical Study to Investigate the Pharmacokinetics and Safety/Tolerability of DA-7218 in Healthy Male Volunteers

Healthy

Korea, Republic of
Trius Therapeutics LLC

Completed

A Pharmacokinetics and Safety Study in Subjects With Renal Impairment

Renal Impairment

United States
Cubist Pharmaceuticals LLC

Completed

Tedizolid Phosphate (TR-701 FA, MK-1986) vs Linezolid for the Treatment of Nosocomial Pneumonia (MK-1986-002)

Pneumonia
University of Southern California
Merck Sharp & Dohme LLC

Completed

Pharmacokinetics of Tedizolid Phosphate in Cystic Fibrosis

Cystic Fibrosis

United States
Trius Therapeutics LLC

Completed

Pharmacokinetics, Safety, and Tolerability of TR-701 Free Acid (FA) in Elderly Subjects

Healthy Subjects

United States
Trius Therapeutics LLC

Completed

Microdialysis and Pharmacokinetic Study of TR-701

Healthy

United States
Trius Therapeutics LLC

Completed

Phase 2 Study of TR-701 in Patients With Complicated Skin and Skin Structure Infections

Skin Diseases, Infectious | Skin Diseases, Bacterial

United States
Bayer
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Intravenous to Oral 6-Day Tedizolid Phosphate vs. Intravenous to Oral 10-Day Linezolid in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI)

Bacterial Infections

China, United States, Philippines, Taiwan
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effects of Tedizolid Phosphate on the Pharmacokinetics and Safety of Midazolam and Rosuvastatin (MK-1986-004)

Skin Diseases, Bacterial
Hospices Civils de Lyon

Completed

Tedizolid Suppressive Antimicrobial Therapy in a Reference Center (TediSAT)

Bone and Joint Infection

France
University of North Carolina, Chapel Hill

Completed

Mechanical Bowel Preparation Before Laparoscopic Hysterectomy and Laparoscopic Sacrocolpopexy: a Randomized Controlled Trial

Laparoscopic Hysterectomy and/or Laparoscopic Sacrocolpopexy

United States
Renovo

Completed

Juvidex (Mannose-6-Phosphate) in Accelerating the Healing of Split Thickness Skin Graft Donor Sites

Wound

United Kingdom
Trius Therapeutics LLC

Completed

A Thorough QT Study of TR-701free Acid (FA) in Healthy Subjects

Healthy Volunteer

United States
Trius Therapeutics LLC
Bayer

Completed

A Phase 2 Safety and Exploratory Skin Lesion Measurement of TR-701 FA Study

Cellulitis | Erysipelas | Major Cutaneous Abscess

United States
Hartford Hospital
Merck Sharp & Dohme LLC

Completed

Tedizolid Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis

Diabetes | Healthy Volunteers | Wound Infection

United States
Cubist Pharmaceuticals LLC

Completed

Study of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012)

Skin Diseases, Infectious | Skin Diseases, Bacterial
Tourcoing Hospital
Eric SENNEVILLE M.D. Ph.D.

Completed

Tedizolid Prolonged Treatment for Prosthetic Joint Infections (TEDIZOAM)

Prosthetic Joint Infection

France
University of Texas Southwestern Medical Center

Completed

Preventing Hypertension and Sympathetic Overactivation by Targeting Phosphate

Hypertension

United States
Taylor's University

Completed

Effectiveness of The Phosphate Mobile App on Serum Phosphorus in Adult Hemodialysis Patients With Hyperphosphatemia

Hyperphosphatemia | End Stage Renal Disease on Dialysis

Malaysia
The University of Queensland
National Health and Medical Research Council, Australia; Cambridge University... and other collaborators

Recruiting

Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE) (PHOSPHATE)

Kidney Failure, Chronic | Hyperphosphatemia

Canada, United Kingdom, Australia, Brazil, New Zealand
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Ruxolitinib Phosphate in Reducing Fatigue in Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
Tufts Medical Center

Completed

Topical Ruxolitinib for the Treatment of Vitiligo

Vitiligo

United States
University of Copenhagen
Stine Kristensen; Gita Krüger Mørch; Rizwan Butt; Ditte Hansen

Not yet recruiting

a Randomized Controlled Trial of the Intake of Organic and Inorganic Phosphate in Peritoneal Dialysis Patients (RCTOIP)

Chronic Kidney Disease Requiring Chronic Dialysis

Denmark
I.M. Sechenov First Moscow State Medical University
Central Scientific Research Institute of Dentistry and Maxillo-facial Surgery... and other collaborators

Completed

Ridge Preservation With New Class of Osteoplastic Materials (RP)

Tooth Extraction | Atrophy of Edentulous Alveolar Ridge

Russian Federation
University of Nebraska
National Cancer Institute (NCI)

Completed

Ruxolitinib Phosphate to Treat Diffuse Large B-Cell or Peripheral T-Cell Non-Hodgkin Lymphoma After Stem Cell Transplant

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma

United States
Yale University
National Center for Advancing Translational Sciences (NCATS)

Suspended

The Impact of Phosphate Metabolism on Healthy Aging

Rickets | Hypophosphatemia | Hypercalciuria | XLH | HHRH

United States
University of Copenhagen
Camilla Storm Slumstrup; Ewa Lewin; Casper Rydahl

Completed

Effect of a Phosphate Modified Diet on Phosphate Balance and Phosphate Metabolism in Predialysis Patients Stage 3-4

Chronic Kidney Disease

Denmark
Jens Rikardt Andersen

Completed

Absorption of Orally Ingested Phosphate in Refeeding Syndrome

Refeeding Syndrome | Cancer of the Head and Neck

Denmark
Laboratoires Mayoly Spindler

Completed

Measurement of Gastric Emptying During and After COLOKIT® Intake

Colonoscopy

France
Neuralstem Inc.

Completed

Single-Dose Pharmacokinetics (PK) Study of Novel Neurogenic Compound NSI-189

Depression

United States
Taipei Medical University Hospital

Recruiting

The Causal Connection Between Sng and Muscle Acidosis

Muscle Acidosis

Taiwan

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