Search clinical trials for: Telotristat Ethyl

Total 931 results

Lexicon Pharmaceuticals

Completed

Study to Evaluate the Pharmacokinetics of Telotristat Ethyl in Subjects With Severe Hepatic Impairment

Hepatic Impairment

United States
TerSera Therapeutics LLC

Completed

Real-world Evidence Study EvaLuating PAtient-Reported Outcomes With XERMELO (RELAX)

Carcinoid Syndrome

United States
M.D. Anderson Cancer Center
TerSera Therapeutics LLC

Recruiting

Telotristat Ethyl for the Treatment of Carcinoid Heart Disease in Patients With Metastatic Neuroendocrine Tumor

Locally Advanced Neuroendocrine Neoplasm | Metastatic Neuroendocrine Neoplasm

United States
Andrew Hendifar, MD
Lexicon Pharmaceuticals

Withdrawn

Open Label Study to Analyze the Effect of Telotristat Ethyl on Weight Regulation/Gain

Pancreatic Cancer | Neuroendocrine Tumors | Cachexia; Cancer
University of Chicago

Withdrawn

Telotristat Ethyl for Reducing Intraoperative Carcinoid Crisis in Patients With Neuroendocrine Tumors

Neuroendocrine Tumors
Chandrikha Chandrasekhara
TerSera Therapeutics LLC

Withdrawn

Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl (NET-PACS)

Diarrhea | Neuroendocrine Tumors | Carcinoid Syndrome

United States
European Organisation for Research and Treatment...
Ipsen

Withdrawn

Lanreotide Combined With Telotristat Ethyl or Placebo for the First-line Treatment in Patients With Advanced Well Differentiated Small Intestinal Neuroendocrine Tumours (siNET) With Highly-functioning Carcinoid Syndrome (TELEFIRST)

Small Intestinal NET | Carcinoid Heart Disease
TerSera Therapeutics LLC

Terminated

A Safety and Efficacy Study of XERMELO® + First-line Chemotherapy in Patients With Advanced Biliary Tract Cancer (TELE-ABC)

Biliary Tract Cancer (BTC)

United States
M.D. Anderson Cancer Center

Withdrawn

Retifanlimab (INCMGA00012) and Telotristat Ethyl for the Treatment of Advanced Neuroendocrine Tumors and Carcinoid Syndrome

Carcinoid Syndrome | Advanced Neuroendocrine Neoplasm
Lexicon Pharmaceuticals

Completed

An Open-Label Food Effect Study of Telotristat Etiprate

Healthy

United States
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms (TELEPATH)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Italy, Netherlands, Spain, Sweden, United Kingdom
Ipsen

Completed

Study to Evaluate a Dose of Telotristat Etiprate in Male and Female With Mild, Moderate and Severe Hepatic Insufficiency and Matched Healthy Subjects

Hepatic Impairment

Moldova, Republic of, Romania
Lowell Anthony, MD
TerSera Therapeutics LLC

Terminated

Telotristat With Lutathera in Neuroendocrine Tumors

Neuroendocrine Tumors

United States
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Spain, Sweden, United Kingdom, Netherlands
Lexicon Pharmaceuticals

Completed

TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome)

Carcinoid Syndrome

United States, Australia, Belgium, France, Germany, Italy, Netherlands, Spain, Sweden, United Kingdom, Canada, Israel
Ipsen

Completed

Study to Compare a Dose of Telotristat Etiprate in Subjects With Renal Impairment With Matched Subjects With Normal Renal Function

Renal Impairment

Moldova, Republic of, Belgium, Germany, Romania
Lexicon Pharmaceuticals

Completed

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome

Carcinoid Syndrome

Germany, United Kingdom
Lexicon Pharmaceuticals

Completed

A Study to Evaluate Safety and Efficacy of Telotristat Etiprate (LX1606) in Participants With Acute, Mild to Moderate Ulcerative Colitis

Ulcerative Colitis

United States, Lithuania, Poland, Slovakia
Photolitec LLC
National Cancer Institute (NCI); Roswell Park Cancer Institute

Recruiting

Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac®

Glioblastoma Multiforme of Brain | Glioma, Sarcomatous

United States
Stanford University

Active, not recruiting

Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

Thyroid Cancer | Anaplastic Thyroid Cancer | Undifferentiated Thyroid Cancer

United States
Unilever R&D
Leiden University Medical Center

Completed

fMRI of Hypothalamic Responses to Taste, Temperature and Glucose (COLD-2)

Healthy

Netherlands
Constellation Pharmaceuticals

Completed

A Study Evaluating CPI-1205 in Patients With B-Cell Lymphomas

B-Cell Lymphoma

United States
Emory University
National Cancer Institute (NCI); Lexicon Pharmaceuticals

Active, not recruiting

Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Unresectable Pancreatic Adenocarcinoma | Recurrent Pancreatic Adenocarcinoma

United States
Altavant Sciences GmbH
Parexel; Altavant Sciences, Inc.

Completed

Multiple-Ascending Dose in Japanese Patients Bridging Study

Healthy

United States
Lexicon Pharmaceuticals

Completed

A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects

Drug-drug Interaction

United States
Altavant Sciences GmbH
PPD

Completed

A Single and Multiple Dose of Rodatristat Ethyl in Healthy Adult Subjects to Evaluate the Effect of Food and Safety

Healthy

United States
New York State Psychiatric Institute

Withdrawn

A PET Study With [11C]PBR-28 and an Experimental Medication, Ethyl Eicosapentaenoic Acid

Bipolar Disorder

United States
Lexicon Pharmaceuticals

Completed

Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Healthy Subjects

Drug Interactions

United States
Promomed, LLC

Completed

Safety and Efficacy of the Therapy With BRAINMAX® for the Treatment of Patients With Asthenia After COVID-19

COVID-19 | Asthenia

Russian Federation
Altavant Sciences GmbH

Completed

A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension (ELEVATE 2)

Pulmonary Arterial Hypertension

United States, Spain, United Kingdom, Czechia, Serbia, Canada, Poland, Italy, Bosnia and Herzegovina, Austria, Germany, Belgium, Bulgaria, France, Latvia, Moldova, Republic of, Ukraine
Lexicon Pharmaceuticals

Completed

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide Therapy

Carcinoid Syndrome

United States
Crimson Biopharm Inc.

Not yet recruiting

CM93 Treatment in Subjects With Epidermal Growth Factor Receptor (EGFR)-Modified Recurrent Glioblastoma (rGBM)

Glioblastoma
Constellation Pharmaceuticals

Completed

ORIOn-E: A Study Evaluating CPI-1205 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
National Center for Complementary and Integrative...

Completed

Ethyl Eicosapentanoic Acid (Ethyl-EPA) for Treating Major Depression

Depressive Disorder | Depression

United States
Amarin Pharma Inc.

Completed

Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) (ANCHOR)

Hypertriglyceridemia

United States
Amarin Pharma Inc.

Completed

Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL (MARINE)

Hypertriglyceridemia

United States, Netherlands, Russian Federation, Ukraine, Denmark, Finland, Germany, India, Italy, Mexico, South Africa
Altavant Sciences GmbH
Covance; Altavant Sciences, Inc.

Completed

Pharmacokinetics and Excretion of Oral [14C]-Rodatristat Ethyl

Healthy

United States
Promomed, LLC

Completed

Efficacy of the Therapy With BRAINMAX® Using fMRI for the Treatment of Patients With Asthenia After COVID-19

COVID-19 | Asthenia | Cognitive Impairment | Functional MRI

Russian Federation
Yale University

Completed

Ethyl-EPA Treatment of Prodromal Patients

Schizophrenia Prodrome
Stanford University

Suspended

Cognitive Effects of Vinpocetine in Healthy Adults and Patients With Epilepsy

Epilepsy

United States
National Cancer Institute (NCI)

Terminated

Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body

Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Inflammatory Carcinoma

United States
Federal University of São Paulo
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Total Contact Insole for Chronic Nonspecific Low Back Pain (LBP) ((LBP))

Chronic Nonspecific Low Back Pain

Brazil
Mochida Pharmaceutical Company, Ltd.
Sumitomo Pharma (Suzhou) Co., Ltd.

Active, not recruiting

Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia

Hypertriglyceridemia

China
Constellation Pharmaceuticals

Active, not recruiting

ProSTAR: A Study Evaluating CPI-1205 in Patients With Metastatic Castration Resistant Prostate Cancer

Metastatic Castration Resistant Prostate Cancer (mCRPC)

United States
TorreyPines Therapeutics

Completed

Study of NGX267 Oral Capsules in Patients With Xerostomia Associated With Sjorgren's Syndrome

Sjogren's Syndrome | Xerostomia

United States
University of Iowa
GlaxoSmithKline

Terminated

Feasibility Study of Omega-3 Fatty Acids in Dialysis Patients

Cardiovascular Disease

United States
DSM Nutritional Products, Inc.

Completed

A Parallel Bioavailability Study of Fish Oil-Ethyl Ester Versus Fish Oil-Triglyceride Versus Krill Oil (KOMPARE)

Healthy Adults
Lundquist Institute for Biomedical Innovation at...
Intermountain Research and Medical Foundation

Completed

Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin Therapy (EVAPORATE)

Hypertriglyceridemia

United States
Takeda

Completed

Long-term Efficacy and Safety Study of TAK-085 in Participants With Hypertriglyceridemia

Hypertriglyceridemia
Amarin Neuroscience Ltd
Huntington Study Group

Completed

TREND-HD - A Trial of Ethyl-EPA (Miraxion™) in Treating Mild to Moderate Huntington's Disease

Huntington Disease

United States, Canada

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