Search clinical trials for: Tinostamustine (EDO-S101)

Total 2705 results

Mundipharma Research Limited

Completed

Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumors

Soft Tissue Sarcoma | Ovarian Cancer | Endometrial Cancer | Small-cell Lung Cancer | Triple-negative Breast Cancer

United States, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

Glioblastoma | Gliosarcoma | MGMT-Unmethylated Glioblastoma

United States
Mundipharma Research Limited

Active, not recruiting

Study of Tinostamustine, First-in-Class Alkylating HDACi Fusion Molecule, in Relapsed/Refractory Hematologic Malignancies

Multiple Myeloma | Hodgkin's Lymphoma | Hematological Malignancies | Cutaneous T Cell Lymphoma

France, United States, Netherlands, Spain, Switzerland, Germany, Italy
Mundipharma Research Limited

Active, not recruiting

Study of Tinostamustine for Adjuvant Treatment of Glioblastoma

Glioblastoma Multiforme

Switzerland, Spain
Staar Surgical Company

Completed

Clinical Performance of a Phakic Intraocular Lens (IOL)

Presbyopia

Spain, Belgium
Mundipharma-EDO GmbH

Terminated

Tinostamustine Conditioning and Autologous Stem Cell (TITANIUM1)

Multiple Myeloma in Relapse | Multiple Myeloma With Failed Remission | Multiple Myeloma Progression

Switzerland, United States, Norway
Tanta University

Completed

Post-Operative Pain Evaluation After Using Different Single-file Root Canal Preparation System: A Randomized Clinical Study

Root Canal Treatment

Egypt
Shanghai Zhongshan Hospital

Unknown

End-expiratory and End-inspiratory Occlusion Tests to Predict Fluid Responsiveness (EEOFR)

Cardiac Surgery

China
Markus Joerger

Recruiting

Tinostamustine and Nivolumab in Advanced Melanoma (ENIgMA)

Malignant Melanoma

Switzerland
Gilead Sciences

Terminated

Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic Malignancies

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large B-cell Lymphoma | Indolent Non-Hodgkin's Lymphoma

United States
Chordate Medical

Completed

Investigation of Kinetic Oscillation Stimulation by the Chordate System S101 in the Treatment of Non Allergic Rhinitis (KOSNAR)

Nasal Congestion | Non-allergic Rhinitis

Finland, Italy, United Kingdom, Greece, Netherlands, Czechia
Faculty of Dental Medicine for Girls

Recruiting

Alt-RAMEC Expansion and Protraction by EDO in Cleft Lip and Palate Patient

Cleft Lip and Palate

Egypt
Faculty of Dental Medicine for Girls

Recruiting

Slow Expansion and Protraction in Cleft Lip and Palate Patients

Cleft Lip and Palate

Egypt
Imperial College London
Imperial College Health Partners

Not yet recruiting

Triple Cardiovascular Disease Detection With an Artificial Intelligence-enabled Stethoscope (TRICORDER)

Heart Failure | Atrial Fibrillation | Heart Valve Diseases | Heart Murmurs | Congestive Heart Failure | Heart Failure With Reduced Ejection Fraction
Staar Surgical Company

Completed

Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL)

Myopia | Myopic Astigmatism

United States
Edgewise Therapeutics, Inc.

Recruiting

A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX) (LYNX)

Duchenne Muscular Dystrophy

United States
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

The ReTAVI Prospective Observational Registry

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Austria, Spain, France, Germany, Italy, Switzerland, Poland, Canada, Israel, Netherlands, Portugal, United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC; Mundipharma-EDO GmbH

Withdrawn

A Phase Ib Combination Study of Rituximab, TinostamustinEAnd CHeckpoint Inhibition With Pembrolizumab in Relapsed/Refractory DLBCL

Relapsed or Refractory Diffuse Large B-cell Lymphoma

United Kingdom
Craig Hospital

Recruiting

Transcutaneous Spinal Cord Stimulation to Promote Walking Recovery After Spinal Cord Injury

Spinal Cord Injuries

United States
Yonsei University

Recruiting

Effect of Soft Robotic Exosuit Assistance in Healthy People

Healthy Person

Korea, Republic of
Edgewise Therapeutics, Inc.
Medpace, Inc.; SYSNAV; ImagingNMD

Recruiting

Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)

Becker Muscular Dystrophy

United States, Netherlands, United Kingdom
Edgewise Therapeutics, Inc.

Completed

Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers

Nervous System Diseases | Genetic Diseases, Inborn | Musculoskeletal Diseases | Muscular Diseases | Neuromuscular Diseases | Muscular Dystrophies | Muscular Disorders, Atrophic | Healthy Volunteer

United States
Johnson & Johnson Vision Care, Inc.

Completed

Evaluating Soft Contact Lens Prototypes for Myopia Control

Visual Acuity

China
Gilead Sciences

Withdrawn

A Phase 2, Single-Arm, Open-Label Study Evaluating the Efficacy and Safety of Single Agent GS 1101 (CAL 101) as Therapy for Previously Treated Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia
Shanghai Zhongshan Hospital

Recruiting

PDO/PDO-TIL/PDOTS for Drug Screen

Liver Cancer | Metastatic Liver Cancer

China
University of Cadiz

Not yet recruiting

Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care. (PRICA-POWFRAIL)

Frailty | Disability Physical | Old Age; Atrophy
National Taiwan University Hospital

Recruiting

Skin Irritation Test of Ten Products

Dermatitic Reaction of Face

Taiwan
Ruijin Hospital
Cellular Biomedicine Group Ltd.

Completed

A Tolerance Clinical Study on Aerosol Inhalation of Mesenchymal Stem Cells Exosomes In Healthy Volunteers

Healthy

China
Akili Interactive Labs, Inc.

Completed

Software Treatment for Actively Reducing Severity of ADHD (STARS-ADHD)

Attention Deficit Disorder With Hyperactivity

United States
Enanta Pharmaceuticals, Inc

Terminated

A Randomized, Double-blind Study to Assess the Safety and Efficacy of EDP-305 in Subjects With Liver-biopsy Proven NASH

Non-Alcoholic Steatohepatitis

United States, Canada, Puerto Rico, United Kingdom, Argentina, Germany
Gilead Sciences

Completed

Study to Investigate Effects of CAL-101 in Subjects With Allergic Rhinitis Exposed to Allergen in an Environmental Chamber

Allergic Rhinitis

Austria
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Completed

A Phase 2a Study to Evaluate EDP-938 in the Virus Challenge Model

RSV Infection

United Kingdom
Akili Interactive Labs, Inc.

Completed

Software Treatment for Actively Reducing Severity of ADHD - Follow Up (STARS-ADHD2)

Attention Deficit Disorder With Hyperactivity

United States
Nemours Children's Clinic

Completed

: A Prospective Study Investigating the Use of the Eko CORE and Eko DUO Electronic Stethoscopes in Pediatric Patients.

Heart Murmurs

United States
Edgewise Therapeutics, Inc.

Recruiting

Phase 2 Study of EDG-5506 in Children and Adolescents With Duchenne Muscular Dystrophy Previously Treated With Gene Therapy (FOX)

Duchenne Muscular Dystrophy

United States
Eko Devices, Inc.

Completed

Development of an Algorithm to Differentiate Heart Murmurs Using Electronic Stethoscopes

Aortic Valve Stenosis | Mitral Regurgitation | Heart Murmurs | Tricuspid Regurgitation | Murmur, Heart | Innocent Murmurs

United States
San Francisco Veterans Affairs Medical Center
VA Office of Research and Development

Completed

Brain Aging in Veterans (BRAVE) Training: A Cognitive Training Pilot Trial in Older Veterans With Traumatic Brain Injury

TBI (Traumatic Brain Injury)

United States
EsoCap AG
FGK Clinical Research GmbH; FGK Representative Service B.V.

Completed

A Study to Investigate the Efficacy and Tolerability of ESO-101 in Patients With Eosinophilic Esophagitis

Eosinophilic Esophagitis

Spain, Switzerland, Netherlands, Germany, Poland
Gilead Sciences

Terminated

An Extension Study for Subjects Who Are Deriving Benefit With Idelalisib (GS-1101; CAL-101) Following Completion of a Prior Idelalisib Study

Lymphoma, Non-Hodgkin | Chronic Lymphocytic Leukemia

United States
Eko Devices, Inc.

Recruiting

Real-World Evaluation of Eko Algorithms in a Point of Care Setting

Atrial Fibrillation | Heart Murmurs | Murmur, Heart | Innocent Murmurs | Pathologic Murmur

United States
VA Office of Research and Development

Completed

Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI

Post Traumatic Stress Disorder | Mild Traumatic Brain Injury, Concussion

United States
University of Oxford

Unknown

A Phase I Study to Assess Ebola Vaccines cAd3-EBO Z and MVA-EBO Z

Ebola Virus Disease

United Kingdom
Erasmus Medical Center

Unknown

Ventricular Tachycardia in Ischemic Cardiomyopathy; a Combined Endo-Epicardial Ablation Within the First Procedure Versus a Stepwise Approach (EPILOGUE)

Ventricular Tachycardia | Ischemic Cardiomyopathy
Laboratoires Pronutri
Expert Clinical Services Organization (ECSOR)

Completed

Efficacy of Trace Elements in the Treatment of Endometriosis: a Pilot Study

Endometriosis

Belgium
Medtronic - MITG

Terminated

ENDO GIA Stapler With Duet Tissue Reinforcement System (TRS) Used in Pulmonary Resections

Lung Disease

Japan
University Hospital, Clermont-Ferrand
Institut ANALGESIA

Recruiting

Cohort of Chronic Pain Patients (e-DOL cohort)

Chronic Pain

France
University Medical Centre Ljubljana
Loyola University

Completed

Endothelial Dysfunction in Perioperative Period (EDOP)

Postoperative Complications | Endothelial Dysfunction
Gilead Sciences

Completed

Safety and Efficacy Study of Idelalisib (GS-1101, CAL-101) in Patients With Previously Treated Low-grade Lymphoma

Follicular Lymphoma | Marginal Zone Lymphoma | Small Lymphocytic Lymphoma | Indolent Non-Hodgkin's Lymphoma

United States
Enanta Pharmaceuticals, Inc
ICON Clinical Research; Triangle Biostatistics

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alcoholic Steatohepatitis

Non-Alcoholic Steatohepatitis

United States, United Kingdom, New Zealand, Canada, France, Puerto Rico
Eko Devices, Inc.

Terminated

Heart Failure Monitoring With Eko Electronic Stethoscopes (HOME0)

Heart Failure | Heart Failure With Preserved Ejection Fraction | Crackles

United States

Search clinical trials for: Tinostamustine (EDO-S101)

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