Search clinical trials for: Treatment B: Naloxone Nasal Spray

Total 893 results

INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray, Naloxone Hydrochloride (HCl) Intravenous (IV) and Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Pharmacokinetics of Multiple Repeated Doses of Intranasal Naloxone

Healthy Subjects | Pharmacokinetics | Opioid Antagonist

United States
State University of New York - Upstate Medical...
Binghamton University

Completed

A Usability Assessment of Naloxone Administration by Untrained Community Members

Harm Reduction | Opioid-use Disorder | Naloxone

United States
Huahui Health

Completed

A Study to Evaluate the Safety and Pharmacokinetics of HH-120 Nasal Spray in Healthy Volunteers

COVID-19

China
Anhui Palo Alto Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of PA9159 Nasal Spray in Healthy Adult Subjects

Allergic Rhinitis

China
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
Finnish Institute for Health and Welfare

Unknown

Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder (NalGamb)

Naloxone | Gambling Disorder | Opioid Antagonist | Pathological Gambling

Finland
VistaGen Therapeutics, Inc.

Terminated

PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge - 2 (Palisade-2)

Social Anxiety Disorder

United States
VistaGen Therapeutics, Inc.

Recruiting

Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-3) (PALISADE-3)

Social Anxiety Disorder

United States
VistaGen Therapeutics, Inc.

Completed

PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge (Palisade-1)

Social Anxiety Disorder

United States
University of Chicago
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Withdrawn

Topical Allstate and Nasal Allergen Challenge

Allergic Rhinitis

United States
Viiral Nordic AB

Completed

A Post-Market Clinical Follow-up Investigation to Verify Performance and Safety of Viiral®Nasal Spray in Subjects With Dry Nose Symptoms

Rhinitis Sicca

Sweden
CEN Biotech
Urgo Research, Innovation & Development

Recruiting

Effectiveness of a Nasal Spray on Viral Respiratory Infections

COVID-19 | Common Cold | Acute Respiratory Tract Infection | Flu, Human

France
Emergent BioSolutions

Completed

Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy Adults

Opioid Overdose

United States
Leiden University Medical Center
U.S. Food and Drug Administration (FDA)

Recruiting

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists (ROAR)

Chronic Opioid Use | Opioid Induced Respiratory Depression

Netherlands
Johns Hopkins University
Cure Addiction Now

Recruiting

Behavioral Pharmacological Examination of a Novel Buprenorphine Induction Method Among Individuals Who Use Fentanyl (NBIM)

Opioid Use Disorder

United States
Imperial College London
GlaxoSmithKline

Completed

Nasal LPS Challenge in Healthy Volunteers

Healthy

United Kingdom
Marinomed Biotech AG

Completed

Demonstration of an Anti-allergic Effect in Subjects Treated With Callergin Nasal Spray in Comparison to Untreated Subjects and Subjects Treated With Vis Alpin® Alpensalz Nasal Spray, All Suffering From Grass Pollen Induced Rhinitis/Rhinoconjunctivitis

Allergic Rhinitis | Allergic Rhinoconjunctivitis

Austria
Oyster Point Pharma, Inc.

Completed

Evaluation of the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (the RAINIER Study)

Dry Eye Disease

United States
University of Electronic Science and Technology...

Completed

Multiple Dose Effect of Oxytocin on Males With High or Low Trait Anxiety

Healthy

China
Sara Espinoza
The University of Texas Health Science Center, Houston; The University of Texas... and other collaborators

Completed

The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity (INOSO)

Obesity | Sedentary Lifestyle | Sarcopenia | Aging | Sarcopenic Obesity

United States
P & B Group
MediAxe CRO

Completed

Efficacy of ADW S-100 Ionized Water Nasal Spray in Decreasing Symptoms of Allergic Rhinitis (SPRA)

Allergic Rhinitis

France
P & B Group
MediAxe CRO

Terminated

Efficacy of ADW S-100 Ionized Water Nasal Spray in Decreasing SARS-Cov-2 Viral Load.

SARS-CoV-2 Infection

France
Marinomed Biotech AG

Completed

Prophylactic Treatment With Carragelose Nasal Spary to Prevent SARS-CoV-2, COVID-19, Infections in Health Care Workers

COVID-19 | Common Cold | Respiratory Viral Infection | Severe Acute Respiratory Syndrome (SARS) Pneumonia | Corona Virus Disease

Austria
Region Skane

Active, not recruiting

Naloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related Complications

Opioid Abuse

Sweden
Serenity Pharmaceuticals, Inc.

Completed

Study to Investigate the Safety and Pharmacokinetics of SER120 Nasal Spray in Elderly Patients With Nocturia

Nocturia

United States
University of Wisconsin, Madison
Procter and Gamble

Completed

Efficacy of Homeopathic Nasal Formulation for Management of Experimental Rhinoviral Colds

Common Cold
McNeil AB

Completed

A Study of an Experimental Nasal Spray in Subjects With Early Signs of the Common Cold

Common Cold

United Kingdom
Herbarium Laboratorio Botanico Ltda

Completed

Evaluation of Cutaneous Acceptability and Perceived Effectiveness of a Nasal Spray (Health Care Products)

Acceptance, Social | Sensitivity, Contact

Brazil
Merck Sharp & Dohme LLC

Completed

A Study in Subjects With Perennial Allergic Rhinitis

Perennial Allergic Rhinitis
Murdoch Childrens Research Institute
Royal Children's Hospital; Monash Health

Recruiting

Intranasal Steroid as Medical Therapy For Sleep-Disordered Breathing in Children (MIST+)

Snoring | Tonsillar Hypertrophy | Sleep Disorder; Breathing-Related | Obstructive Sleep Apnea of Child | Sleep Disorders in Children | Adenoidal Disorder

Australia
University Hospital, Antwerp

Unknown

Study of Probiotic Potential of Lactobacillus Strains in the Upper Respiratory Tract After Nasal Spray Application

Chronic Rhinosinusitis (Diagnosis) | Probiotics | Healthy Volunteers | Nasal Disease | Sprays

Belgium
Alcon Research

Completed

Safety and Efficacy of AL-53817 Nasal Spray Solution

Allergies | Nasal Allergies

United States
Chulalongkorn University

Not yet recruiting

Efficacy and Safety of Longan Extract Spray (P80 Spray) in Volunteers With Coronavirus Disease 2019 (COVID-19)

Infection Viral
Beijing Ditan Hospital

Completed

A Clinical Study to Assess Preliminary Efficacy, Safety and Tolerability of HH-120 Nasal Spray in COVID-19 Patients

Coronavirus Disease 2019(COVID-19)

China
Beijing Ditan Hospital

Completed

A Study of HH-120 Nasal Spray in Close Contacts of Those Diagnosed With COVID-19

COVID-19 | SARS-CoV-2 Infection

China
Xlear, Inc
Metanoic Health Ltd.

Not yet recruiting

Xylitol Based Nasal Spray for COVID-19 Treatment

Respiratory Viral Infection
University of Delaware

Completed

Long-term Use of Proton Pump Inhibitors May Cause Vitamin B12 Deficiency in the Institutionalized Elderly

Vitamin B12 Deficiency

United States
Puressentiel
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Efficacy of Puressentiel Protective Nasal Spray in Allergic Rhinitis (EPPNS)

Allergic Rhinitis Due to Grass Pollen | Allergic Inflammation
GlaxoSmithKline

Completed

Once-Daily Investigational Nasal Spray In Adults And Adolescents With Seasonal Allergic Rhinitis (SAR)

Rhinitis, Allergic, Seasonal

United States
GlaxoSmithKline

Completed

Study In Adolescent And Adult Subjects 12 Years Of Age And Older With Seasonal Allergic Rhinitis To Assess Onset of Action

Rhinitis, Allergic, Seasonal

United States
GlaxoSmithKline

Completed

A Study Of GW685698X For The Treatment Of Perennial Allergic Rhinitis In Pediatrics

Rhinitis, Allergic, Perennial

United States
Nasus Pharma

Completed

A Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres Powder

Opioid Overdose

Canada
Laboratoire de la Mer
Slb Pharma

Not yet recruiting

PMCF to Assess Real-life Usage Effectiveness, Safety and Patient Satisfaction of a Range of Hypertonic Seawater-based Decongestant Nasal Sprays

Allergic Rhinitis | URTI
Organon and Co

Completed

Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05529)

Allergic Rhinitis
Bausch & Lomb Incorporated

Completed

Safety and Efficacy of Bepotastine Besilate Nasal Spray in the Treatment of Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

United States
Organon and Co

Completed

An Exploratory Study of Nasonex in Patients With Moderate to Severe Persistent Allergic Rhinitis and Intermittent Asthma

Asthma | Allergic Rhinitis
Beijing Ditan Hospital

Completed

A Study to Assess the Efficacy of HH-120 Nasal Spray for Prevention of SARS-CoV-2 Infection in Adult Close Contacts of Individuals Infected With SARS-CoV-2

SARS-CoV-2 Infection

China
GlaxoSmithKline

Completed

Effect of the GSK2245035 on the Allergen-induced Asthmatic Response

Asthma

United Kingdom, Germany

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