Search clinical trials for: Trikafta [orange tablet containing ELX 100mg, TEZ 50mg, and IVA 75mg]

Total 59 results

University of Southern California

Recruiting

Impact of Rifabutin on the Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor

Drug Drug Interaction

United States
Dong-A ST Co., Ltd.

Active, not recruiting

Phase 1 Clinical Trial to Evaluate the Safety, PK and PD of DA-5207 TDS in Healthy Adults

Healthy

Korea, Republic of
Corcept Therapeutics

Completed

First-in-human Study in Healthy Subjects

Healthy

United Kingdom
Global Alliance for TB Drug Development

Completed

Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary | Pulmonary Disease | Multi Drug Resistant Tuberculosis | Drug Sensitive Tuberculosis | Drug-resistant Tuberculosis | Mycobacterium Tuberculosis Infection

United States
TaiGen Biotechnology Co., Ltd.

Completed

A Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects and the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics

Healthy Volunteers
China National Center for Cardiovascular Diseases

Recruiting

LDL Cholesterol TARGETs in OLDer Patients (Age≥75 Years) With ASCVD (TARGET OLD)

Atherosclerotic Cardiovascular Disease | LDL Cholesterol | Older Patients

China
Daiichi Sankyo, Inc.

Completed

Hydrochlorothiazide as add-on to Olmesartan/Amlodipine in Hypertension

Essential Hypertension

France, Poland, Ukraine, Belgium, Germany, Spain, Bulgaria, Romania, Denmark, Russian Federation, Netherlands, Austria, Slovakia, Czechia
Cairo University

Completed

Clinical and Immunohisochemical Evaluation of Chemopreventive Effect of Thymoquinone on Oral Potentially Malignant Lesions.

Premalignant Lesion

Egypt
Daiichi Sankyo Co., Ltd.

Completed

Phase 2 Study of DS-8500a in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Japan
GlaxoSmithKline

Completed

Dose Ranging Study Evaluating the Efficacy and Safety of GSK2190915 Administered Once Daily

Asthma

United States, Japan, Romania, Ukraine, Bulgaria, Poland
Fundacion SEIMC-GESIDA

Active, not recruiting

Phase IV, a Clinical Trial to Assess Safety and Convenience of the Change From DTG/3TC to BIC/FTC/TAF in People With HIV, Good Virological Control and Neuropsychiatric Vulnerabilities (MIND)

HIV Infections

Spain
Seasons Biotechnology (Taizhou) Co., Ltd.

Completed

Single Dose Study to Evaluate Dose-proportionality of Vortioxetine Hemihydrobromide Orally Disintegrating Tablets

Major Depressive Disorder (MDD

India
AstraZeneca

Completed

The PK and PD of Dapagliflozin Therapy in Combination With Insulin in Japanese Subjects With T1DM

Type 1 Diabetes Mellitus

Japan
Dong-A ST Co., Ltd.

Unknown

A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | Metabolic Disease | Renal Disease

Korea, Republic of
GlaxoSmithKline

Completed

Controlled-release Paroxetine in Major Depressive Disorder (Double-blind, Placebo-controlled Study)

Depressive Disorder

Korea, Republic of, Japan
Martin Huelsmann

Recruiting

NT-proBNP Selected Prevention of Cardiac Events in Diabetic Patients

Heart Diseases | Diabetes Mellitus, Type 2

New Zealand, Austria, Netherlands, Spain, United Kingdom
Dong Wha Pharmaceutical Co. Ltd.

Completed

the Pharmacokinetic Profiles of Linagliptin With DW1029M (PLID)

Healthy

Korea, Republic of
AstraZeneca

Completed

Assess Pharmacokinetics of Fostamatinib in Fed and Fasted State in Combination With Ranitidine to Assess Bioavailability (PK Combination)

Pharmacokinetics

United States
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years

Cystic Fibrosis

United States, United Kingdom, Canada, Australia, Germany
Galen Limited

Completed

Bioequivalence Study of Co-codamol 15mg/500mg Capsules vs Co-codamol 30mg/500mg Tablets in Healthy Subjects

Healthy

United Kingdom
Dong-A ST Co., Ltd.

Completed

Phase 1 Clinical Trial of DA-5207 in Healthy Adults

Healthy

Korea, Republic of
GlaxoSmithKline

Completed

Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Amlodipine and Losartan in Health Volunteers

Hypertension

Australia
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Effects of SGLT2 Inhibitor on Hemodynamic Parameters in Resistant Hypertensive Subjects

Hypertension | Obesity | Diabetes Mellitus, Type 2 | Blood Pressure | Vascular Stiffness | Cardiac Hypertrophy | Microalbuminuria

Brazil
GL Pharm Tech Corporation

Completed

PK Study of Pregabalin GLARS Tablet 150mg and IR Formulation After Multiple Dosing Under Fed Condition in Healthy Male Subjects (GLA5PR-102)

Healthy

Korea, Republic of
Corcept Therapeutics

Completed

CORT125281 Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD)

Healthy

United Kingdom
The Faculty Hospital Na Bulovce

Completed

Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures

Small Bowel Obstruction | Acute Appendicitis | Perforated Gastroduodenal Ulcer

Czech Republic
Starpharma Pty Ltd

Completed

Efficacy and Safety Study of SPL7013 Gel to Prevent the Recurrence of Bacterial Vaginosis (BV)

Bacterial Vaginosis

United States, Bulgaria, Czechia, Hungary, Ukraine, United Kingdom
Institut de Médecine et d'Epidémiologie Appliquée...
Pierre and Marie Curie University

Recruiting

Switch to TAF+FTC+BIC in HIV-1-infected Patients Over 65 Years Old at Risk of Polymedication (BICOLDER)

HIV Infections

France
The University of Texas Medical Branch, Galveston
Pfizer; University of Texas Southwestern Medical Center

Completed

Caduet and TLC Intervention in Metabolic Syndrome

Metabolic Syndrome
Northwestern University

Completed

Healthy Combine Study

Healthy

United States
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Terminated

Efficacy, Tolerability and Acceptability of Biktarvy by TPLWH

Human Immunodeficiency Virus

United Kingdom
Mundipharma Oy

Completed

OXN PR Compared to OXY PR in Subjects With Postoperative Pain After Knee Arthroplasty (OXN4505)

Post Operative Pain

Finland
Weill Medical College of Cornell University
Gilead Sciences

Active, not recruiting

Switch to Bictegravir/Emtricitabine/Tenofovir Alafenamide After Renal Transplant

HIV Infections | Renal Transplant Rejection

United States
TYK Medicines, Inc

Recruiting

A Study of TY-302 in Patients With Advanced Solid Tumors

Breast Cancer | Solid Tumor

China
University of Miami

Completed

Implementation of Onsite, Rapid ART Initiation Among People Who Inject Drugs Living With HIV at Syringe Services Program

HIV Infections | Drug Use | Harm Reduction

United States
University of Michigan
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetic Study of Single-Dose Modified Release Glipizide in Healthy Volunteers

Human Gastrointestinal Physiology Data

United States
Assaf-Harofeh Medical Center

Unknown

Thromboelastography As An Assessment Tool for Possible Clopidogrel and Aspirin Resistance (TEG)

Acute ST SEgment Elevation Myocardial Infarction

Israel
Rhonda Brand
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs (APTAMER)

HIV | Medication Adherence

United States
Chelsea and Westminster NHS Foundation Trust

Recruiting

The Effect of Biktarvy (B/F/TAF) on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers

HIV-1-infection

United Kingdom
Ruijin Hospital

Unknown

CTOP/ITE/MTX Compared With CHOP as the First-line Therapy for Newly Diagnosed Young Patients With T Cell Lymphoma

ALK-negative Anaplastic Large Cell Lymphoma | Peripherial T Cell Lymphoma,Not Otherwise Specified | Angioimmunoblastic T Cell Lymphoma | Enteropathy Associated T Cell Lymphoma | Hepatosplenic T Cell Lymphoma | Subcutaneous Panniculitis Like T Cell Lymphoma

China
Sabyasachi Sen

Terminated

Effect of Saxagliptin and Dapagliflozin on Endothelial Progenitor Cell in Patients With Type 2 Diabetes Mellitus

Cardiovascular Diseases | Diabetes Mellitus, Type 2

United States
Jordan Feld
University Health Network, Toronto

Recruiting

Transplantation Using Hepatitis C Positive Donors, A Safety Trial

Hepatitis C | Kidney Transplant Infection | Heart Transplant Infection | Lung Transplant Infection | Kidney Pancreas Infection

Canada
Peking Union Medical College Hospital
Chinese Academy of Sciences

Unknown

Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents

Type2 Diabetes Mellitus

China
Medical University of Vienna

Completed

The Role of the P2Y12 Receptor in Tissue Factor Induced Coagulation

Sepsis | Healthy Volunteers

Austria
Oman Medical Speciality Board

Recruiting

Comparison of Efficacy of Metoclopramide , Promethazine and Prochloroperazine in the Treatment of Vertigo. (BBPVOMSBAFH)

Peripheral Vertigo

Oman
Daewoong Pharmaceutical Co. LTD.

Completed

Clinical Trial to Evaluate the Efficacy and Safety of OLOMAX Tab

Hypertension | Dyslipidemias

Korea, Republic of
Assiut University

Unknown

Comparison Between Rifampicin and Gemifloxacin and Ciprofloxacin in Treatment of Rhinoscleroma

Rhinoscleroma

Egypt
Hanmi Pharmaceutical Company Limited

Completed

The Efficacy and Safety Study of Anti-hypertension Combination Drug in Patients Uncontrolled With Monotherapy.

Hypertension
251 Hellenic Air Force & VA General Hospital
Laikο General Hospital, Athens; 424 General Military Hospital

Active, not recruiting

Alendronate in an Weekly Effervescent Tablet Formulation Following Denosumab Discontinuation (BAD)

Postmenopausal Osteoporosis

Greece
University Hospital of Split

Enrolling by invitation

The Efficacy of Tamsulosin and Tadalafil Compared to Placebo in the Treatment and Prevention of Urinary Disorders After Transperineal Prostate Biopsy

Quality of Life | Pain | Lower Urinary Tract Symptoms | Voiding Disorders

Croatia

Search clinical trials for: Trikafta [orange tablet containing ELX 100mg, TEZ 50mg, and IVA 75mg]

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