Search clinical trials for: trospium chloride

Total 3083 results

University of North Carolina, Chapel Hill
American Urogynecologic Society

Completed

The Effect of Anticholinergics on Cognitive Function in the Elderly (ACE)

Urinary Bladder, Overactive | Cognitive Function | Mental Competency

United States
Endo Pharmaceuticals
Alkermes, Inc.

Completed

Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Allergan

Completed

Efficacy of Sanctura XR (Trospium Chloride) for Reducing Overactive Bladder Symptoms in Female Subjects Refractory to Detrol LA (Tolterodine Tartrate Extended Release) Daily

Overactive Bladder

United States
Allergan

Completed

Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART) Trial

Overactive Bladder | Pharmacokinetics | Elderly

United States
Allergan

Completed

Trospium Chloride XR in Obese Female Patients With Overactive Bladder

Obesity | Overactive Bladder | Incontinence

United States
Karuna Therapeutics

Terminated

An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia (PENNANT)

Schizophrenia

United States
Karuna Therapeutics

Completed

A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-3)

Schizophrenia | Schizophrenia; Psychosis

United States, Ukraine
Karuna Therapeutics

Enrolling by invitation

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

Schizophrenia

United States, Bulgaria, Serbia
Karuna Therapeutics

Completed

An Extension Study to Assess Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-4)

Schizophrenia

United States, Ukraine
Karuna Therapeutics

Active, not recruiting

An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5)

Schizophrenia

United States
Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia (ARISE)

Schizophrenia

United States, Bulgaria, Serbia
Karuna Therapeutics

Completed

A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-2)

Schizophrenia | Schizophrenia; Psychosis

United States
The University of Texas Medical Branch, Galveston
National Institute on Aging (NIA)

Recruiting

Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls

Urinary Bladder, Overactive | Urinary Incontinence | Accidental Falls

United States
Mansoura University
Amiri Hospital

Suspended

Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms:

Quality of Life | Ureter Obstruction | Ureter Stone

Egypt
Becky Clarkson
National Institute on Aging (NIA)

Recruiting

Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence

Urgency Urinary Incontinence

United States
Karuna Therapeutics
Zai Lab (Shanghai) Co., Ltd.

Recruiting

A Study to Assess the Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Chinese Adult Subjects With DSM-5 Schizophrenia (UNITE-001)

Schizophrenia

China
Allergan

Completed

Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects

Healthy

United States
Taris Biomedical LLC

Completed

Safety and Tolerability of TAR-302-5018 in Subjects With Idiopathic Overactive Bladder

Idiopathic Overactive Bladder With Urinary Incontinence

United States
Allergan

Completed

Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART-II) Trial

Overactive Bladder

United States
Karuna Therapeutics

Completed

A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-1)

Schizophrenia

United States
Taris Biomedical LLC

Completed

Safety and Tolerability of TAR-302-5018 in Subjects With Neurogenic Detrusor Overactivity Resulting From Spinal Cord Injury

Neurogenic Detrusor Overactivity

United States
Dr. R. Pfleger Chemische Fabrik GmbH

Completed

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Pharmacokinetics | Drug Interaction Potentiation | Inhibition Enzyme
Ain Shams University

Recruiting

Gabapentin Versus Trospium Chloride for Prevention of a Catheter-related Bladder Discomfort Inside the ICU

Catheter-related Bladder Discomfort (CRBD)

Egypt
M.D. Anderson Cancer Center
Bayer; Prostate Cancer Foundation

Completed

Radium 223 in Castrate Resistant Prostate Cancer Bone Metastases

Prostate Cancer

United States
Bayer

Completed

Alpharadin™ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the Skeleton

Prostate Cancer | Pharmacokinetics | Metastases

United States
Karuna Therapeutics

Completed

Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium

Schizophrenia

United States
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer | Prostate Carcinoma Metastatic in the Bone

United States
Bayer

Completed

BAY88-8223, Alpharadin, Breast Cancer Patients With Bone Dominant Disease

Breast Cancer | Bone Metastases

Belgium, United Kingdom, Norway
McMaster University
Hamilton Health Sciences Corporation

Completed

Fluids in Sepsis and Septic Shock (FISSH)

Sepsis | Septic Shock

Canada
University of Jena

Completed

Sino-nasal Inhalation of Sodium Chloride 6,0% in Patients With Cystic Fibrosis and Chronic Rhinosinusitis

Cystic Fibrosis | Rhinosinusitis

Germany
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Nebulised Hypertonic Saline in Children and Young People With Neuromuscular Disease and Cerebral Palsy

Neuromuscular Diseases

United Kingdom
Aga Khan University

Unknown

Comparison of Enteral Versus Intravenous Potassium Supplementation (EIPS)

Acute Hypokalemia

Pakistan
National Cancer Institute (NCI)

Completed

Berberine Chloride in Preventing Colorectal Cancer in Patients With Ulcerative Colitis in Remission

Ulcerative Colitis

United States, China
Federal University of São Paulo

Completed

Fluid Therapy During Brain Tumor Resection in Children

Brain Neoplasms

Brazil
Bayer

Completed

PK in Pts With HRPC & Skeletal Metastes

Prostatic Neoplasms

United Kingdom
National Cancer Institute (NCI)

Recruiting

Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, the RadiCaL Study

Clear Cell Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Chromophobe Renal Cell Carcinoma | Papillary Renal Cell Carcinoma | Collecting Duct Carcinoma | Kidney Medullary Carcinoma | Advanced Renal Cell Carcinoma | Unclassified Renal Cell Carcinoma

United States
Bayside Health
Australian and New Zealand College of Anaesthetists

Completed

Limiting IV Chloride to Reduce AKI After Cardiac Surgery (LICRA)

Patients Undergoing Cardiothoracic Surgery

Australia
Göteborg University

Terminated

Saline Injections for Prophylactic Treatment of Chronic Migraine

Chronic Migraine

Sweden
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bayer; Janssen, LP; Prostate Cancer Clinical Trials Consortium

Completed

Phase IB Trial of Radium-223 and Niraparib in Patients With Castrate Resistant Prostate Cancer (NiraRad)

Stage IV Prostate Adenocarcinoma | Hormone-refractory Prostate Cancer | Prostate Carcinoma Metastatic to the Bone

United States
Frank Mose
Herning Hospital

Completed

The Effect of Orally Administrated Nitrate on Renal Parameters and Systemic Haemodynamics (APNI)

Hypertension

Denmark
University Hospital, Linkoeping

Unknown

Colloid Osmotic Pressure and Osmolality in Hyponatremia

Hyponatremia

Sweden
University Medical Center Groningen

Completed

Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients (GRIP-COMPASS)

Cardiac Surgery | Critically Ill | Thoracic Surgery

Netherlands
Institut d'Anesthesiologie des Alpes Maritimes
Université de Nice Sophia Antipolis; Medical University of Grenoble

Completed

Preventive Sodium Lactate and Traumatic Brain Injury

Head Trauma

France
Ain Shams University

Recruiting

Incidence of Acute Kidney Injury and Mortality in Critically Ill Patients: Urinary Chloride as a Prognostic Marker

Acute Kidney Injury

Egypt
Ziekenhuis Oost-Limburg

Completed

Liberal Use of Sodium in Ambulatory Heart Failure (LUSA-HF)

Heart Failure

Belgium
National Institute of Diabetes and Digestive and...

Terminated

Pre-ESRD Syndrome in High Risk African Americans

Blood Pressure

United States
M.D. Anderson Cancer Center
Bayer

Completed

Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer

Breast Cancer

United States
Amsterdam UMC, location VUmc

Active, not recruiting

Rhenium-188-HEDP vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal Therapy (RaRe)

Prostate Cancer Metastatic to Bone

Netherlands
Imam Abdulrahman Bin Faisal University

Unknown

Type and Frequency of Nasal Irrigation in Rhinosinusitis Patients

Otorhinolaryngologic Diseases | Rhinosinusitis

Saudi Arabia
Haudongchun Co., Ltd.

Unknown

Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosis

Bacterial Vaginosis | HUDC_VT | Haudongchun

Korea, Republic of

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