Search clinical trials for: Tumor Necrosis Factor

Total 30664 results

University of California, San Francisco

Completed

A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
El-Hussuna, Alaa, M.D.

Completed

Anti Tumor Necrosis Factor Alpha Agents and Surgical Stress Response

Inflammatory Bowel Diseases

Denmark
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

TNF-Bound Colloidal Gold in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Assiut University

Unknown

The Role of C1q Tumor Necrosis Factor-related Protein 6 in Breast Cancer

Breast Cancer
Kasr El Aini Hospital

Recruiting

Vitreous Level Of Tumor Necrosis Factor Alpha In Patients With Retinal Vein Occlusion

Retinal Vein Occlusion

Egypt
Seoul National University Hospital

Unknown

Clinical Study of Anti-tumor Necrosis Factor Therapy in Patients With Takayasu Arteritis

Takayasu's Arteritis

Korea, Republic of
Sichuan Clover Biopharmaceuticals, Inc.

Recruiting

A Clinical Trial Evaluating SCB-219M in in Chemotherapy-induced Thrombocytopenia (CIT)

Chemotherapy-induced Thrombocytopenia (CIT)

China
EMD Serono

Terminated

Onercept in the Treatment and Re-Treatment of Subjects With Moderate to Severe Plaque Psoriasis

Arthritis, Psoriatic

United States, Canada
Refnot-Pharm Ltd

Completed

Effect of Refnot on Immunity in Cancer Patients (R-2)

Solid Tumor
National Cancer Institute (NCI)

Completed

Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or Leg

Recurrent Melanoma | Stage III Melanoma

United States
Institut d'Investigació Biomèdica de Girona Dr....

Completed

Golimumab Effect in the Modulation of Gut Microbiota in Ulcerative Colitis (GOLI2015)

Ulcerative Colitis

Spain
Kliniken im Naturpark Altmuehltal

Unknown

Physiological Intermolecular Modification Spectroscopy (PIMS) in Ulcerative Colitis With Golimumab

Ulcerative Colitis

Germany
NorthShore University HealthSystem
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Effects of TNF Blockade on Human BPH/LUTS

Benign Prostatic Hyperplasia (BPH)

United States
Tianjin Medical University

Recruiting

A Study of Adalimumab in Acute Vogt-Koyanagi-Harada Disease

Vogt-Koyanagi-Harada Disease | Adalimumab

China
Gunay ER

Completed

Enthesitis Assessment Before and After Anti-Tumor Necrosis Factor Treatment in Spondyloarthritis

Spondyloarthritis | Enthesitis | Anti-Tumor Necrosis Factor Drugs
Centre Hospitalier Universitaire de Nīmes
Pfizer

Completed

Evaluation of TNFα Blockers Monotherapy in Early Rheumatoid Arthritis in France

Rheumatoid Arthritis
Groupe d'Etude Therapeutique des Affections Inflammatoires...

Completed

Intensive Treatment to Reach the Target With Golimumab in ulcErative coliTis - In-TARGET (In-TARGET)

ULCERATIVE COLITIS

France, Belgium
Janssen Research & Development, LLC

Completed

A Study to Assess the Safety and Pharmacokinetics of Subcutaneously Administered Golimumab, a Human Anti-TNFα Antibody, in Pediatric Patients With Moderate to Severe Active Ulcerative Colitis

Colitis, Ulcerative

United States, France, Belgium, Israel, Canada, Netherlands, Austria, Poland, Denmark, Germany
Peking Union Medical College Hospital

Unknown

Effectiveness and Adherence of Golimumab in Rheumatoid Arthritis

Arthritis, Rheumatoid

China
University Ghent
Merck Sharp & Dohme LLC; the Flanders Institute for Biotechnology

Completed

Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation (GO-GUT)

Axial Spondyloarthritis

Belgium
Janssen Research & Development, LLC

No longer available

Pre-Approval Access to Golimumab Subcutaneous for the Treatment of Stage 3 Type-1 Diabetes Mellitus in Children and Young Adults

Diabetes Mellitus, Type 1

United States
Guy's and St Thomas' NHS Foundation Trust
Merck Sharp & Dohme LLC

Completed

Study of the Golimumab Exposure-Response Relationship Using Serum Trough Levels (GO-LEVEL)

Ulcerative Colitis

United Kingdom
Merck Sharp & Dohme LLC

Completed

Correlation of Soluble Suppression of Tumorigenicity 2 (ST2) With Golimumab (MK-8259) Response in Participants With Ulcerative Colitis (UC) (MK-8529-022). (EVOLUTION)

Colitis, Ulcerative
Janssen Pharmaceutical K.K.

Completed

A Safety and Effectiveness Study of Golimumab in Japanese Patients With Moderately to Severely Active Ulcerative Colitis.

Colitis, Ulcerative

Japan
Janssen-Cilag, S.A.

Terminated

Registry for Analysis of Compliance in Colombian Participants With Rheumatoid Arthritis Exposed to Golimumab (Go-Compl-Ar)

Rheumatoid Arthritis

Colombia
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Accuracy of a Subset of the Length-109 Probe Set Panel (a Genetic Test) in Predicting Response to Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative

France, Ukraine, United States, Poland, Bulgaria, Canada, Netherlands, Belgium, Russian Federation, Germany, Hungary, Czech Republic
House Research Institute
Janssen Services, LLC

Terminated

Intratympanic Injection for Autoimmune Inner Ear Disease (AIED)

Autoimmune Inner Ear Disease
American University of Beirut Medical Center

Recruiting

Intravitreal Adalimumab Versus Subcutaneous Adalimumab in Non-infectious Uveitis (IVAS)

Uveitis | Non-Infectious Uveitis

Lebanon
Inmune Bio, Inc.

Withdrawn

Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurodegenerative Diseases | Dementia | Mild Cognitive Impairment (MCI) | Alzheimer Disease | Tauopathies
AbbVie

Active, not recruiting

Long-term Safety and Efficacy Study of Adalimumab in Pediatric Subjects With Ulcerative Colitis

Ulcerative Colitis

United States, Japan, Poland, Slovakia, Spain, United Kingdom
Merck Sharp & Dohme LLC
Johnson & Johnson

Completed

Effect of Golimumab in Participants With Active Axial Spondyloarthritis (P07642, MK-8259-006) (GO-AHEAD)

Spondylitis, Ankylosing
Istituto Clinico Humanitas

Unknown

Golimumab in Steroid-dependent Ulcerative Colitis: Induction and Maintenance of Clinical and Endoscopic Remission (UC-GOL)

Colitis, Ulcerative

Italy
Mabscale, LLC

Recruiting

Study Evaluation of the Efficacy, Safety and Immunogenicity of Adalimumab in Comparison With Humira®

Plaque Psoriasis

Russian Federation
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

"Comparison of the Efficacy and Safety of Adalimumab to That of Tocilizumab in Severe Uveitis of Behçet's Disease" (UVB)

Behcet's Uveitis
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Relationship Between Polymorphism of Heat Shock Protein 70 Gene and Hepatocellular Carcinoma (HSP70)

Hepatocellular Carcinoma

Taiwan
Bozok University

Completed

Effect of Preoperative Anxiety on Fetus in Pregnant Women

Preoperative Anxiety | Cytokines

Turkey
National Institute of Arthritis and Musculoskeletal...

Completed

Blocking Tumor Necrosis Factor in Ankylosing Spondylitis

Spondylitis, Ankylosing

United States
Wenjie Zheng

Terminated

Golimumab for the Treatment of Refractory Behcet's Uveitis

Behcet Syndrome | Uveitis

China
Centocor, Inc.

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Golimumab in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis

United States
Centocor, Inc.

Completed

A Study of the Pharmacokinetics of Golimumab in Chinese Male Subjects

Healthy Adult Chinese Males

China
Institute of Biomedical Chemistry, Russia
Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy

Completed

Predicting the Response of Patients With Rheumatoid Arthritis to Treatment With Genetically Engineered Biological Drugs and Janus (JAK) Kinase Inhibitors

Rheumatoid Arthritis

Russian Federation
AbbVie

Active, not recruiting

A Study to Assess Change in Disease Activity and Adverse Events of Adalimumab in Chinese Participants Requiring High Dose Corticosteroids for Active Non-Infectious Intermediate, Posterior, or Pan-Uveitis

Non-infectious Intermediate Posterior- or Pan-uveitis

China
Johnson & Johnson Private Limited

Completed

A Study of Golimumab in the Treatment of Indian Participants With Active Spondyloarthropathy of Ankylosing Spondylitis or Psoriatic Arthritis

Arthritis, Psoriatic | Spondylitis, Ankylosing

India
Janssen Research & Development, LLC

Completed

A Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes (T1GER)

Diabetes Mellitus, Type 1

United States
Medical University of Graz

Completed

Golimumab in Juvenile Idiopathic Arthritis-associated Uveitis Failing Adalimumab

JIA Associated Uveitis
National Institute of Diabetes and Digestive and...
University of South Florida

Withdrawn

Anti-TNFα to Delay or Prevent Progression to Stage 3 T1D

Diabetes Mellitus, Type 1
Janssen Research & Development, LLC

Completed

A Study to Evaluate SIMPONI (Golimumab) Therapy in Children, Adolescents and Young Adults With Pre-Symptomatic Type 1 Diabetes

Pre-Symptomatic Type 1 Diabetes

United States, Finland, Sweden
University Hospital, Ghent
Janssen Biologics B.V.

Completed

Exploration of TNF-alpha Blockade With Golimumab in the Induction of Clinical Remission in Patients With Early Peripheral Spondyloarthritis (SpA) According to ASAS-criteria (CRESPA)

Peripheral Spondylarthritis

Belgium
Hoffmann-La Roche

Completed

A Comparative Study to Observe the Effect of Concomitant Use of Corticosteroid Treatment in Rheumatoid Arthritis (RA) Participants Who Are Treated With a Tumor Necrosis Factor (TNF) Inhibitor or Tocilizumab (TCZ) as Their Second Biological Treatment.

Rheumatoid Arthritis

Sweden
Bio-Thera Solutions

Completed

Comparative Study of BAT2506 With Simponi® in Participants With Active Psoriatic Arthritis

Psoriatic Arthritis

China

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