Search clinical trials for: Urokinase and Dornase alfa

Total 2875 results

Azienda Ospedaliera di Padova
Hoffmann-La Roche

Unknown

Dornase Alfa and Urokinase for Kids With Pleural Empyema (DUKE)

Pleural Empyema

Italy
Nicole Hamblett
University of Washington; Dartmouth-Hitchcock Medical Center; Cystic Fibrosis...

Completed

Impact of Discontinuing Dornase Alfa in People With CF on Highly Effective CFTR Modulator Therapy-A SIMPLIFY Sub-Study (SIMPLIFY-DN)

Cystic Fibrosis

United States
University of Melbourne

Recruiting

Improving Early Reperfusion With Adjuvant Dornase Alfa in Large Vessel Ischemic Stroke (EXTEND-IA DNase)

Ischemic Stroke

Australia
University of Vermont
Genentech, Inc.

Completed

Nasally Delivered Pulmozyme for Sinusitis in Cystic Fibrosis

Sinusitis | Cystic Fibrosis

United States
Nicole Hamblett
University of Washington; Dartmouth-Hitchcock Medical Center; Cystic Fibrosis...

Completed

Impact of Discontinuing Chronic Therapies in People With Cystic Fibrosis on Highly Effective CFTR Modulator Therapy (SIMPLIFY)

Cystic Fibrosis

United States
University Hospital Tuebingen
Joachim Riethmueller, Dr. med.

Unknown

Time of Ventilation and Lung Function of Ventilated Patients Under Therapy With Dornase Alfa

Long Term Ventilation

Germany
JHL Biotech, Inc.

Completed

A Comparative Safety and Pharmacokinetic Study of JHL1922 and Pulmozyme® in Healthy Subjects

Healthy Subjects

Netherlands
Boston Children's Hospital
Brigham and Women's Hospital; South Shore Hospital

Recruiting

Pulmozyme to Improve COVID-19 ARDS Outcomes

COVID

United States
Genentech, Inc.

Terminated

A Study of Pulmozyme® (Dornase Alpha) in 3- to 5-Year-Old Patients With Cystic Fibrosis

Cystic Fibrosis
University of Colorado, Denver
Genentech, Inc.

Completed

Treatment of Clogged Tympanostomy Tubes: An Off-Label Use of Dornase Alfa (Pulmozyme®)

Otitis Media

United States
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Efficacy of Pulmozyme® on Arterial Recanalization in Post-thrombectomy Patients Managed for Ischemic Stroke (NETs-target) (NETs-target)

Ischemic Stroke

France
Genentech, Inc.

Terminated

A Trial of Pulmozyme Withdrawal on Exercise Tolerance in Cystic Fibrosis Subjects With Severe Lung Disease (TOPIC)

Cystic Fibrosis

United States
Genentech, Inc.

Completed

A Study of the Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer System in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
University of Jena

Completed

Nasal Inhalation of Pulmozyme in Patients With Cystic Fibrosis and Chronic Rhinosinusitis

Cystic Fibrosis | Rhinosinusitis

Germany
AO GENERIUM

Completed

Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis

Fibrosis | Cystic Fibrosis

Russian Federation
University Medical Centre Ljubljana

Terminated

Usefulness of DORNASE in COVID-19 on HFNO

COVID-19 Pneumonia

Slovenia
University College, London

Completed

Nebulised Dornase Alfa for Treatment of COVID-19 (COVASE)

Hypoxia | COVID19

United Kingdom
University of Missouri-Columbia

Completed

Dornase Alfa for ARDS in Patients With Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) (DORNASESARS2)

SARS-CoV 2 | ARDS

United States
UConn Health

Withdrawn

Pulmozyme for Sjogren's Associated Cough

Cough | Sjogren's Syndrome

United States
Georgetown University
Genentech, Inc.

Completed

Dornase Alfa Therapy for Ventilator Associated Lung Infections in the Neonatal Intensive Care Unit (NICU) (PVAIN)

Pulmonary Infections

United States
Fondation Ophtalmologique Adolphe de Rothschild
University Hospital, Strasbourg, France; Centre Hospitalier Régional Metz-Thionville

Terminated

Efficacy and Safety of aerosolizedDornase Alfa Administration in Patients With COVID19 Induced ARDS (COVIDORNASE) (COVIDORNASE)

COVID-19 | Acute Respiratory Distress Syndrome

France
University of Medicine and Dentistry of New Jersey

Completed

Impact of Nebulized Dornase Alpha on Mechanically Ventilated Patients

Atelectasis | Ventilation, Mechanical

United States
Eastern Regional Medical Center

Recruiting

Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural Effusions

Loculated or Non-draining Malignant Pleural Effusions

United States
Ludwig-Maximilians - University of Munich
University Hospital Erlangen; University Hospital Regensburg

Not yet recruiting

Reduction of SystemiC Inflammation After Ischemic Stroke by Intravenous DNase Administration (ReSCInD) (ReSCInD)

Ischemic Stroke | Inflammatory Response

Germany
Northwestern University
Genentech, Inc.

Unknown

Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy

Head and Neck Cancer

United States
The Alfred
The Alfred Research Trusts Small Project Grant.; Dr Carey Denholm and Laura...

Completed

Preliminary Study of Dornase Alfa to Treat Chest Infections Post Lung Transplant.

Lower Respiratory Tract Infection | Lung Transplant Infection

Australia
The Hospital for Sick Children
Canadian Institutes of Health Research (CIHR); Unity Health Toronto; Children... and other collaborators

Completed

Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial)

Pleural Empyema

Canada
Milton S. Hershey Medical Center
Genentech, Inc.

Withdrawn

Pulmozyme in Cystic Fibrosis With Sinusitis

Sinusitis | Cystic Fibrosis

United States
Beijing Chao Yang Hospital

Completed

12-h and 2-h Urokinase Regimes of Pulmonary Thromboembolism in China (UKPTEC)

Thromboembolism | Pulmonary Embolism

China
AO GENERIUM

Completed

Tigerase® Efficacy and Safety as Part of Complex Therapy in Patients With COVID-19

COVID-19 | Coronavirus Disease 2019

Russian Federation
University Hospital, Strasbourg, France

Recruiting

Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma (TRAUMADORNASE)

Multiple Trauma | Respiratory Distress Syndrome, Adult

France
National Taiwan University Hospital

Unknown

Intrapleural Urokinase for Retained Hemothorax (NTUH)

Retained Hemothorax

Taiwan
Second Affiliated Hospital of Nanchang University
Changhai Hospital

Recruiting

Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)

Aneurysmal Subarachnoid Hemorrhage

China
University of Roma La Sapienza

Unknown

Local Thrombolytics Before Thrombectomy in STEMI (DISSOLUTION)

Coronary Artery Disease
Universitair Ziekenhuis Brussel

Completed

Efficacy of Urokinase Containing Locking Solutions for Thrombotic Dysfunction of Tunneled Hemodialysis Catheters

Kidney Failure, Chronic | Vascular Access Devices

Belgium
Children's Mercy Hospital Kansas City

Withdrawn

Empyema Treated With tPA & DNAse

Empyema

United States
Chang Gung Memorial Hospital

Completed

Thrombolysis With Intra-arterial Urokinase

Arterial Occlusion Mesenteric Artery Superior

Taiwan
Universitair Ziekenhuis Brussel

Completed

Prevention of Dialysis Catheter Malfunction With Prophylactic Use of a Taurolidine Containing Urokinase

Infection | Patency

Belgium
Duke University

Completed

Efficacy of Percussive Ventilation Therapy (MetaNeb ®) Compared With Mucolytic Agents for Atelectasis in the Mechanically Ventilated Pediatric Patient

Atelectasis
University of Pittsburgh
University of Colorado, Denver; Children's Hospital of Philadelphia; University... and other collaborators

Completed

Supporting American Indian/Alaska Native Mothers and Daughters in Reducing Gestational Diabetes Risk

Gestational Diabetes Mellitus

United States
General Hospital of Shenyang Military Region

Withdrawn

Intravenous Thrombolysis Registry for Acute Ischemic Stroke in China

Ischemic Stroke

China
Beijing Chao Yang Hospital
General Hospital of Shenyang Military Region; Qingdao University; Shenzhen People... and other collaborators

Completed

Recombinant Streptokinase Versus Urokinase in Pulmonary Embolism in China (RESUPEC) (RESUPEC)

Pulmonary Embolism | Pulmonary Thromboembolism

China
Poitiers University Hospital

Completed

Prognostic Value of Soluble Urokinase Plasminogen Activation Receptor (SUPAR) to Rule Out Complications in Patients Admitted in Emergency Department for Acute Abdominal Pain. (GRADIENT)

Mortality | Abdominal Pain | Emergency Department | Soluble Urokinase Plasminogen Activation Receptor

France
University of Thessaly

Completed

SuPAR in Adult Patients With Covid-19 (SPARCOL)

Covid19

Greece
Amgen

Completed

Study for the Treatment of Anemia in Patients With Non-myeloid Malignancies Receiving Multicycle Chemotherapy.

Anemia
University of Oklahoma

Completed

Dornase Alpha Versus Hypertonic Saline for Lung Atelectasis in Non-Cystic Fibrosis Patients

Atelectasis

United States
The First Affiliated Hospital of Zhengzhou University
Techpool Bio-Pharma Co., Ltd.

Recruiting

Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study

Acute Ischemic Stroke

China
Pharmaxis

Completed

Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Hospital Universitari Vall d'Hebron Research Institute

Completed

Efficacy and Security of Intrapleurally Alteplase vs Urokinase for the Treatment of Complicated Parapneumonic Effusion and Empyema

Pleural Diseases | Pleural Effusion | Empyema, Pleural

Spain
Jonsson Comprehensive Cancer Center
Amgen

Completed

Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer

Lymphoma | Leukemia | Anemia | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Precancerous/Nonmalignant Condition

United States

Search clinical trials for: Urokinase and Dornase alfa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Saudi Arabia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations