Search clinical trials for: valproate

Total 363 results

University of Birmingham

Active, not recruiting

Efficacy and Safety Trial of Sodium Valproate, in Paediatric and Adult Patients With Wolfram Syndrome

Wolfram Syndrome

France, United Kingdom, Poland, Spain
Ewha Womans University

Withdrawn

Cytidine- and Creatine-Containing Drug in Treating Bipolar Depression

Bipolar Depression

Korea, Republic of
Ewha Womans University Mokdong Hospital

Withdrawn

Combined Cytidine and Creatine-containing Drug in the Treatment of the Bipolar Depression

Depression, Bipolar

Korea, Republic of
Xijing Hospital

Unknown

Traumatic Neuroprotection and Epilepsy Prevention of Valproate Acid (VPA)

Traumatic Brain Injury

China
All India Institute of Medical Sciences, New Delhi

Unknown

Study of Efficacy and Safety of Valproic Acid in Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia

India
LEO Pharma
Bayer

Completed

An Observational Study Investigating the Treatment Satisfaction of Atopic Dermatitis Patients Who Have Switched to Ointment (W/O Emulsion) Formulation of Very Strong Class Topical Corticosteroids (Ointment TS-AD)

Dermatitis, Atopic

Japan
Kathmandu University
Asian Pharmaceuticals Pvt. Ltd.

Active, not recruiting

Bioequivalence Study of Sodium Valproate and Valproic Acid Tablets (BA-BE)

Epilepsy

Nepal
Tanta University

Recruiting

Zolmitriptane as Prophylaxis for Chilhood Migraine

Migraine

Egypt
University of Virginia

Terminated

Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent Glioblastoma

Glioblastoma

United States
LEO Pharma
Bayer

Completed

A Study to Learn More About the Relationship Between the Development of a Gap in the Upper Lip (Cleft Lip) or in the Roof of the Mouth (Cleft Palate) in Newborns and the Use of Glucocorticoids by the Mother During Pregnancy: a Meta-analysis

Relationship Between the Exposure of Glucocorticoids During Pregnancy and Orofacial Cleft Development

Germany
Sanofi

Completed

Safety Study of Sodium Divalproate in Bipolar Disorder in Adolescents (ADOKOT)

Bipolar Disorder

France
Steve N. Caritis, MD
AMAG Pharmaceuticals, Inc.

Terminated

17-OHPC in Pregnancy: IM vs SC Routes

Preterm Birth

United States
The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies

Preterm Birth

United States
Postgraduate Institute of Dental Sciences Rohtak

Unknown

Bone Mineral Density and Periodontal Status in Patients on Antiepileptic Drug

Alveolar Bone Loss

India
GlaxoSmithKline

Completed

Lamotrigine Pregnancy Registry (LAM05)

Epilepsy | Bipolar Disorder
Lehigh Valley Hospital

Terminated

A Randomized Trial of Cerclage Versus 17 α-Hydroxyprogesterone Caproate for Treatment of a Short Cervix

Mid Trimester Cervical Shortening

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy of 17 Alpha-hydroxyprogesterones Caproate for the Prevention of Preterm Delivery

Preterm Delivery

France
Soroka University Medical Center

Withdrawn

Progesterone for First Trimester Vaginal Bleeding

Premature Birth | Pre-Eclampsia | Fetal Growth Retardation | Threatened Abortion | Abruptio Placentae

Israel
The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)

Pregnancy | Preterm Birth | Multifetal

United States
Assiut University

Completed

Intramuscular Hydroxyprogesterone Caproate and Placenta Previa

Preterm Labor

Egypt
Yale University

Withdrawn

Treatment of Preterm Labor With 17 Alpha-hydroxyprogesterone Caproate

Premature Birth | Premature Labor
M.D. Anderson Cancer Center
Cancer Prevention Research Institute of Texas

Enrolling by invitation

Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy

Delirium | Epileptics | Neuroleptics

United States
University of Pittsburgh
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Study of Pharmacology of 17-OHPC in Pregnancy

Pregnancy

United States
Shanghai Mental Health Center
Shanghai Pudong New Area Mental Health Center; The Affiliated Brain Hospital...

Completed

Disturbance of Plasma Cytokine Parameters in Clozapine-Resistant Treatment-Refractory Schizophrenia (CTRS) and Their Association With Combination Therapy

Schizophrenia

China
AMAG Pharmaceuticals, Inc.

Terminated

Study Assessing Injection Pain of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) When Administered Via Subcutaneous Auto-injector vs Intramuscular Injection Via Needle and Syringe in Healthy Post-menopausal Women

Assessing Injection Pain of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) in Healthy Post-menopausal Women

United States
Lumara Health, Inc.

Completed

Pharmacokinetic Study of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) and Its Metabolites in Blood

Pregnancy

United States
Meir Medical Center

Unknown

17 Alfa Hydroxyprogesterone Caproate Versus Natural Progesterone for the Prevention of Preterm Labor

Pregnancy

Israel
AMAG Pharmaceuticals, Inc.

Completed

Comparing Bioavailability When Preservative-free Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) is Administered as an Intramuscular Manual Injection or as a Subcutaneous Injection Using an Auto-injector in Healthy Post-menopausal Women

Comparing Bioavailability When Makena® is Administered in Healthy Post-menopausal Women

United States
Saint Thomas Hospital, Panama

Unknown

Prevention of Preterm Labor in Patients With a Previous Episode of Threatened Preterm Labor With Progesterone

Preterm Birth | Obstetric Labor, Premature

Panama
National Cheng-Kung University Hospital

Unknown

Combination of Dextromethorphan and Memantine in Treating Bipolar Disorder

Bipolar Disorder II

Taiwan
Obstetrix Medical Group

Completed

Progesterone (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM) (17PinPROM)

Preterm Delivery

United States
Lund University Hospital

Completed

Pretreatment With Valproate Prior to Immunotherapy Targeting Cluster of Differentiation Antigen 20 in Chronic Lymphocytic Leukemia (PREVAIL)

Chronic Lymphocytic Leukemia

Sweden
Hillel Yaffe Medical Center

Unknown

Safety and Efficacy of Intravenous Valproate in Pediatric Status Epilepticus and Acute Repetitive Seizures

Status Epilepticus

Israel
Obstetrix Medical Group

Completed

17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies (170HP)

Preterm Birth

United States
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Improving Pregnancy Outcomes With Progesterone (IPOP)

HIV-1-infection | Pre-term Birth

Zambia
Instituto do Cancer do Estado de São Paulo
University of Sao Paulo

Completed

Valproic Acid and Platinum-based Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer | Oropharyngeal Cancer | Oral Cavity Cancer

Brazil
Sanofi

Completed

Study of Valproate in Young Patients Suffering From Epilepsy (VAPOP)

Epilepsy

France
Eunice Kennedy Shriver National Institute of Child...
National Institute of Mental Health (NIMH)

Unknown

Valproate Response in Aggressive Autistic Adolescents

Autism

United States
Seoul National University Hospital

Completed

Efficacy and Safety of Oral Valproic Acid for Retinitis Pigmentosa (VPA_RP)

Eye Diseases | Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa | Eye Disease, Hereditary

Korea, Republic of
University College, London

Completed

Sodium Valproate for GSDV

McArdle Disease | Glycogen Storage Disease Type V

Denmark, United Kingdom
Foundation Fighting Blindness
United States Department of Defense

Completed

Trial of Oral Valproic Acid for Retinitis Pigmentosa (VPA)

Retinitis Pigmentosa

United States
Hoffmann-La Roche

Completed

A Study on the Effects of Valproate on the Pharmacokinetics of RO4917838 in Healthy Volunteers

Healthy Volunteer

France
Centre of Chinese Medicine, Georgia
Rea Rehabilitation Centre, Georgia

Completed

Study of Efficacy of Sodium Valproate in Therapy of Bronchial Asthma

Bronchial Asthma
University Hospital, Bordeaux
Sanofi-Synthelabo

Terminated

Efficacy of Valproate in Peripheral Neuropathic Pain

Neuralgia | Neuropathic Peripheral Pain

France
Assiut University

Completed

Valproic Acid in Treating Cyanotic Breath Holding Spells

Breathhold

Egypt
Washington University School of Medicine

Completed

Effects of Atypical Antipsychotic and Valproate Combination Therapy on Glucose and Lipid Metabolism in Schizophrenia (DepIVGTT)

Insulin Resistance | Body Composition

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Pfizer

Active, not recruiting

Sunitinib Malate or Valproic Acid in Preventing Metastasis in Patients With High-Risk Uveal Melanoma

Ciliary Body and Choroid Melanoma, Medium/Large Size | Ciliary Body and Choroid Melanoma, Small Size | Iris Melanoma | Stage IIIA Intraocular Melanoma | Stage IIIB Intraocular Melanoma | Stage IIIC Intraocular Melanoma | Stage I Intraocular Melanoma | Stage IIA Intraocular Melanoma | Stage IIB Intraocular... and other conditions

United States
University of Leicester

Recruiting

The Val-CARD Trial (Val-CARD)

Coronary Artery Disease | Cardiac Valve Disease | Organ Failure, Multiple

United Kingdom
Sanofi

Completed

VALID : VAlproate Versus LIthium in Bipolar Disorders

Bipolar Disorder
University of Oklahoma

Completed

Comparing IM vs. Vaginal Progesterone for Pre-term Birth

Premature Birth | Infant, Premature

United States

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