Search clinical trials for: Voclosporin

Total 231 results

Weill Medical College of Cornell University

Available

Special Access for the Use of Voclosporin for Kidney Transplantation

Immunosuppression | Transplantation, Kidney

United States
Aurinia Pharmaceuticals Inc.
United BioSource, LLC

Recruiting

LUPKYNIS US Registry Trial

Lupus Nephritis

United States
Aurinia Pharmaceuticals Inc.

Terminated

Dose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental Glomerulosclerosis (AURONA™)

Focal Segmental Glomerulosclerosis

United States, Dominican Republic
Aurinia Pharmaceuticals Inc.

Completed

Aurinia Early Urinary Protein Reduction Predicts Response (AURION)

Lupus Nephritis

Malaysia
Aurinia Pharmaceuticals Inc.

Completed

Voclosporin in Healthy Japanese Volunteers

Volunteers

Philippines
Aurinia Pharmaceuticals Inc.

Completed

Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque Psoriasis Patients (ESSENCE)

Psoriasis

Canada, Germany, Poland
Aurinia Pharmaceuticals Inc.

Completed

A 36-Week Extension to Protocol ISA04-03 (SPIRIT)

Psoriasis

Canada
Aurinia Pharmaceuticals Inc.

Completed

Randomized Placebo-controlled Study of ISA247 in Plaque Psoriasis (SPIRIT)

Psoriasis

Canada
Aurinia Pharmaceuticals Inc.
Labcorp Drug Development Inc

Recruiting

Voclosporin in Adolescents With Lupus Nephritis (VOCAL)

Adolescent Lupus Nephritis

United States
Aurinia Pharmaceuticals Inc.

Completed

Aurinia Renal Assessments 2: Aurinia Renal Response in Lupus With Voclosporin (AURORA 2)

Lupus Nephritis

United States
Aurinia Pharmaceuticals Inc.

Completed

Aurinia Renal Response in Active Lupus With Voclosporin (AURORA)

Lupus Nephritis

United States, Argentina, Belarus, Brazil, Bulgaria, Canada, Chile, Colombia, Costa Rica, Croatia, Dominican Republic, Guatemala, Japan, Korea, Republic of, Malaysia, Mexico, Netherlands, North Macedonia, Peru, Philippines, Poland, Puerto Rico and more
Aurinia Pharmaceuticals Inc.
Labcorp Corporation of America Holdings, Inc

Not yet recruiting

Long-Term Voclosporin Treatment in Adolescent Subjects With Lupus Nephritis (VOCAL-EXT)

Adolescent Lupus Nephritis

United States
The Cleveland Clinic

Completed

Anti-thymocyte Globulin and Cyclosporine as First-Line Therapy in Treating Patients With Severe Aplastic Anemia

Aplastic Anemia

United States
Rennes University Hospital
Novartis

Terminated

Switch From Tacrolimus to Cyclosporin in the Treatment of Recurrent Hepatitis C After Liver Transplantation

Chronic Hepatitis C | Evidence of Liver Transplantation

France
Lux Biosciences, Inc.

Completed

A Dose-Escalation Study to Assess the Safety and Tolerability of LX214 Ophthalmic Solution in Healthy Volunteers, Followed by an Open-Label Evaluation of LX214 in Patients With Keratoconjunctivitis Sicca (KCS)

Keratoconjunctivitis Sicca

United States
London School of Hygiene and Tropical Medicine
Armauer Hansen Research Institute, Ethiopia; Alert Hospital, Ethiopia; Homes...

Completed

Ciclosporin in the Management of New Erythema Nodosum Leprosum

Leprosy

Ethiopia
National Cancer Institute (NCI)

Terminated

Dasatinib and Cyclosporine in Treating Patients With Chronic Myelogenous Leukemia Refractory or Intolerant to Imatinib Mesylate

Accelerated Phase Chronic Myelogenous Leukemia | Chronic Phase Chronic Myelogenous Leukemia | Relapsing Chronic Myelogenous Leukemia | Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
National Cancer Institute (NCI)

Active, not recruiting

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Stage IIIA Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer AJCC v7 | Solid Neoplasm

United States, Canada
Seoul National University Hospital

Completed

Comparison Study of Psoriasis Severity Assessment Tools

Psoriasis

Korea, Republic of
Aurinia Pharmaceuticals Inc.

Completed

AURA-LV: Aurinia Urinary Protein Reduction Active - Lupus With Voclosporin (AURA-LV) (AURA-LV)

Lupus Nephritis

United States, Bangladesh, Belarus, Bulgaria, China, Ecuador, Georgia, Guatemala, Korea, Republic of, Mexico, Philippines, Poland, Russian Federation, Serbia, Singapore, Spain, Sri Lanka, Taiwan, Thailand, Ukraine
Aurinia Pharmaceuticals Inc.

Withdrawn

Safety and Efficacy Study of Voclosporin and Tacrolimus in Transplantation (INSPIRE)

Renal Transplantation
Aurinia Pharmaceuticals Inc.

Completed

Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye Syndrome (AUDREY)

Keratoconjunctivitis Sicca | Dry Eye Syndrome

United States
Chengdu University of Traditional Chinese Medicine

Completed

AST Combined With 0.05% Cyclosporin Eye Drop Improve Corneal Nerve Density in Patients With SS Dry Eye (AST/SS)

Dry Eye | Sjogren's Syndrome | Ocular Surface Disease

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Low-Dose Total Body Irradiation and Donor Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Patients With Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, or Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions

United States, Germany, Italy
London School of Hygiene and Tropical Medicine
Armauer Hansen Research Institute, Ethiopia; Alert Hospital, Ethiopia; Homes...

Completed

Ciclosporin in the Management of Chronic or Recurrent Erythema Nodosum Leprosum

Leprosy

Ethiopia
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Safety and Effectiveness of Trappa Ethanolamine Tablets Combined With Ciclosporin in the Treatment of Primary Treatment of Non-severe Aplastic Anemia

Non-severe Aplastic Anemia

China
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Aurinia Pharmaceuticals Inc.

Completed

Study of ISA247 (Voclosporin) in De Novo Renal Transplantation (PROMISE)

Kidney Diseases

United States, Canada
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Ciclosporin

Healthy

United Kingdom
National Cancer Institute (NCI)

Completed

Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer

HIV Infection | Unspecified Childhood Solid Tumor, Protocol Specific | Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal... and other conditions

United States
Institute of Hematology & Blood Diseases Hospital

Unknown

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013)

Urination Disorders | Thrombosis | Proteinuria | Anemia, Hemolytic | Hemoglobinuria, Paroxysmal | Hemoglobinuria | Paroxysmal Nocturnal Hemoglobinuria | Bone Marrow Failure | Aplastic Anemia,

China
Institute of Hematology & Blood Diseases Hospital

Unknown

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria (PNH-2012)

Urination Disorders | Thrombosis | Proteinuria | Anemia, Hemolytic | Hemoglobinuria, Paroxysmal | Hemoglobinuria | Paroxysmal Nocturnal Hemoglobinuria | Bone Marrow Failure | Aplastic Anemia,

China
Hospices Civils de Lyon

Completed

Cyclosporine and Prognosis in Acute Myocardial Infarction (MI) Patients (CIRCUS)

ST Elevation Acute Myocardial Infarction

France, Spain, Belgium
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Severe Combined Immunodeficiency | Adenosine Deaminase Deficiency | Immune System Disorder | Autosomal Recessive Disorder | Purine-Nucleoside Phosphorylase Deficiency | Severe Combined Immunodeficiency With Absence of T and B Cells | X-Linked Severe Combined Immunodeficiency

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Cyclosporine, Pravastatin Sodium, Etoposide, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Shandong University
National Natural Science Foundation of China

Unknown

Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Severe Aplastic Anemia

Aplastic Anemia

China
Mahidol University

Completed

Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye

Stevens-Johnson Syndrome

Thailand
Safaa AA Khaled
Assiut University

Completed

Combination of Thrombopoietin Mimetic and Immunosuppressive Therapy in Aplastic Anaemia

Aplastic Anemia

Egypt
National Institute of Allergy and Infectious Diseases...

Recruiting

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus (DIVERT)

Systemic Lupus Erythematosus

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Germany, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Stage IV Kidney Cancer

Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant

Clear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent... and other conditions

United States, Germany, Italy
Fred Hutchinson Cancer Research Center/University...
National Cancer Institute (NCI)

Completed

Reduced Intensity Donor Stem Cell Transplant in Treating Patients With High Risk Acute Lymphocytic Leukemia in Complete Remission

Adult Acute Lymphoblastic Leukemia in Remission | Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Reduced Intensity Donor Peripheral Blood Stem Cell Transplant in Treating Patients With De Novo or Secondary Acute Myeloid Leukemia in Remission

Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies

Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma and other conditions

United States
Stanford University

Completed

Ph II of Non-myeloablative Allogeneic Transplantation Using TLI & ATG In Patients w/ Cutaneous T Cell Lymphoma

Lymphoma, Non-Hodgkin | Mycoses | Lymphoma, T-Cell, Cutaneous | Sezary Syndrome | Cutaneous T-cell Lymphoma | Bone Marrow Transplant Failure

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
NeuroVive Pharmaceutical AB

Completed

Copenhagen Head Injury Ciclosporin (CHIC) Study (CHIC)

Traumatic Brain Injury

Denmark

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