Search clinical trials for: Xyrem+%28sodium+oxybate%29+oral+solution

Total 91 results

Jazz Pharmaceuticals

Completed

Trial of Xyrem® (Sodium Oxybate) for the Treatment of Narcolepsy

Narcolepsy

Canada
Brigham and Women's Hospital

Withdrawn

Evaluation of the Efficacy of Sodium Oxybate (Xyrem®) in Treatment of Post-traumatic Narcolepsy and Post-traumatic Hypersomnia

Traumatic Brain Injury | Narcolepsy | Hypersomnia

United States
Jazz Pharmaceuticals

Completed

Trial Comparing the Effects of Xyrem (Sodium Oxybate) With Placebo for the Treatment of Fibromyalgia

Fibromyalgia

United States
UCB Pharma SA

Completed

Exploratory Clinical Study to Evaluate Sodium Oxybate (Xyrem) on Potential Endocrine Changes

Narcolepsy With Cataplexy

Belgium
Tufts Medical Center

Withdrawn

The Effect of Sodium Oxybate on Sleep Architecture

Mechanically Ventilated ICU Patients

United States
Jazz Pharmaceuticals

Completed

Safety and Tolerability Study Comparing Sodium Oxybate Given as an Oral Solution to a Single-blinded Combination of Oral Tablets Plus Oral Solution in Subjects With Fibromyalgia

Fibromyalgia

United States
Baylor College of Medicine
Jazz Pharmaceuticals

Completed

Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson's Disease (PD) (Xyrem)

Parkinson Disease
St. Luke's Hospital, Chesterfield, Missouri
Jazz Pharmaceuticals

Completed

Enhancing Slow Wave Sleep With Sodium Oxybate

Sleep

United States
Kristina Simonyan
National Institutes of Health (NIH); National Institute on Deafness and Other...

Completed

Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response

Spasmodic Dysphonia | Voice Tremor

United States
University Hospital, Montpellier

Completed

Sodium Oxybate in Idiopathic Hypersomnia (SODHI)

Idiopathic Hypersomnia

France
Jazz Pharmaceuticals

Completed

Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy

Narcolepsy

United States, France, Germany, Switzerland
Washington University School of Medicine
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep Induction

Amyloid-beta

United States
Nathan Kline Institute for Psychiatric Research
Jazz Pharmaceuticals

Completed

Sodium Oxybate in Schizophrenia With Insomnia

Schizophrenia | Insomnia Related to Schizophrenia (307.42)

United States
Christian Baumann

Completed

Study of the Symptomatic Effects of Nocturnal Sodium Oxybate in Parkinson's Disease (PD-Xyrem)

Sleep-wake Disturbances in Motor-phase Parkinson's Disease

Switzerland
Ramin Khatami

Unknown

Sodium Oxybate in Patients With Episodic and Chronic Cluster Headache (SOinCH)

Cluster Headache
Concert Pharmaceuticals

Completed

A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and Pharmacodynamics

Narcolepsy, Excessive Daytime Sleepiness

United Kingdom
University of Medicine and Dentistry of New Jersey
Jazz Pharmaceuticals

Terminated

Use of Xyrem to Improve Sleep in Chronic Fatigue Syndrome

Chronic Fatigue Syndrome

United States
Imperial College London
Medical Research Council

Completed

SWS And Daytime Functioning in Chronic FatiguE Syndrome (SAFFE) (SAFFE)

Chronic Fatigue Syndrome

United Kingdom
Centre for Addiction and Mental Health

Completed

Xyrem and Brain Dopamine in Narcolepsy

Healthy Controls | Narcolepsy With Cataplexy

Canada
Orphan Medical

Completed

Safety and Efficacy of Xyrem Oral Solution (Sodium Oxybate) Compared With Placebo in Narcoleptic Patients

Narcolepsy

United States, Canada, Switzerland
Orphan Medical
Johns Hopkins University

Completed

Physiological, Behavioral and Subjective Effects of Drugs (GHB)

Sedative Abuse

United States
IBSA Institut Biochimique SA
Cromsource

Active, not recruiting

Use of Tirosint®-SOL or Tablet Formulations of Levothyroxine in Pediatric Patients With Congenital Hypothyroidism (CH)

Congenital Hypothyroidism

United States
Federal University of Mato Grosso

Completed

Body Composition and Serum Biochemistry After Intravenous Infusion or Oral Intake of Saline in Healthy Volunteers

Edema | Perioperative/Postoperative Complications

Brazil
G. d'Annunzio University

Completed

PrevenTion of Contrast-inducEd nephroAThy With urinE Alkalinization (TEATE)

Acute Kidney Injury | Contrast Media Reaction

Italy
Stanford University

Completed

Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.

Sleep Initiation and Maintenance Disorders

United States
Clinica Universidad de Navarra, Universidad de...

Completed

Prevention of Contrast Induced Nephropathy (NIC) by Intravenous Versus Oral Rehydration (NIC)

KIDNEY FAILURE, ACUTE

Spain
Bausch Health Americas, Inc.

Completed

Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing

Colon Cleansing

United States
Ligand Pharmaceuticals

Completed

Safety and Tolerability Study of Oral LGD-6972 for Type 2 Diabetes Mellitus (L6972-02)

Type 2 Diabetes Mellitus

United States
Baxter Healthcare Corporation
Halozyme Therapeutics

Withdrawn

Efficacy and Time and Resources for Hylenex-facilitated SC Rehydration Versus ORT for Dehydrated Children in the Emergency Department (ED) (INFUSE-TM)

Dehydration
National Cancer Center, Korea
Seoul National University Hospital; Seoul National University Bundang Hospital and other collaborators

Unknown

Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery

Colorectal Cancer

Korea, Republic of
US Department of Veterans Affairs

Completed

Safety and Efficacy of Routine Colonoscopy Preparations

Spinal Cord Injury

United States
UCB BIOSCIENCES, Inc.
Pharmaceutical Research Associates

Completed

A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications (VALOR)

Epilepsy

United States, Australia, Belgium, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
The Western Pennsylvania Hospital
West Penn Allegheny Health System

Withdrawn

Oral Versus Intravenous Hydration to Prevent Contrast Induced Nephropathy (HYDRATE)

Contrast Induced Nephropathy

United States
Inje University

Completed

Efficacy, Safety and Tolerability of Split-dose of PEG Compared With NaP Solution for Colonoscopy Preparation: A Randomized, Controlled Trial (SPEN)

Bowel Preparation, Efficacy, Tolerability, Safety

Korea, Republic of
Laboratorio Farmaceutico Ct S.r.l.

Completed

Evaluation of the Efficacy of Sodium Oxybate in the Long-term Maintenance of Abstinence in Alcoholic Patients (GATE2)

Alcohol Dependence | Alcohol Use Disorder (AUD)
University of Aarhus

Completed

Lactate in the Gut

Healthy | Hyperlactatemia | Lactate

Denmark
Psychiatric University Hospital, Zurich

Completed

Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress Disorder (TRAUMA-PRO)

Inflammatory Response | Psychological Trauma | Physiological Stress | Intrusive Thought

Switzerland
UCB BIOSCIENCES, Inc.
PRA Health Sciences

Terminated

Efficacy Evaluation of Intravenous Brivaracetam and Phenytoin in Subjects With Nonconvulsive Electrographic Seizures

Nonconvulsive Electrographic Seizures

United States
Barnes-Jewish Hospital
Washington University School of Medicine

Terminated

Concentrated Saline Infusions and Increased Dietary Sodium With Diuretics for Heart Failure With Kidney Dysfunction

Renal Insufficiency | Congestive Heart Failure

United States
UCB BIOSCIENCES, Inc.

Completed

Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic Seizures (VALUE)

Epilepsy

United States, Australia, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
Boehringer Ingelheim

Completed

BI 10773 Administered as Oral Solution to Healthy Male Volunteers

Healthy
Lawrence Charles Hookey
Pendopharm

Recruiting

Evaluation of an Oral Sodium Sulfate Solution for Patients With Prior Difficult or Incomplete Cleansing (OSS)

Colonoscopy | Bowel Preparation

Canada
Liz Darling
London Health Sciences Centre; Trillium Health Partners; Oak Valley Health

Not yet recruiting

Oral Sodium Bicarbonate for the Prevention of Labour Dystocia (Labour-Aide)

Labour Dystocia
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Terminated

Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children and Adolescents Aged From 7 to Less Than 18 Years Old With Autism Spectrum Disorder

Autism Spectrum Disorder (ASD)

Spain, Hungary, Poland, Brazil, France, Italy, Portugal, United Kingdom, Germany, Netherlands
U.S. Army Medical Research and Development Command
Walter Reed Army Medical Center

Completed

Use of Sodium Stibogluconate as a Treatment for Leishmaniasis

Leishmaniasis

United States
scPharmaceuticals, Inc.

Completed

Furosemide Pharmacodynamics and Pharmacokinetics After Subcutaneous or Oral Administration (FUROPHARM-HF)

Heart Failure

Netherlands
Dow University of Health Sciences

Completed

Role of Propolis Endodontic Irrigant on Post-Operative Pain

Symptomatic Irreversible Pulpitis | Post-operative Pain

Pakistan
Vaxart
Biomedical Advanced Research and Development Authority

Completed

A Phase 2 Influenza A Challenge Study Following Oral Administration of an H1N1 HA Ad-Vector Seasonal Flu Vaccine

Influenza

United States
Emory University
American Heart Association

Completed

FFA-Induced Hypertension and Endothelial Dysfunction

Hypertension | Endothelial Dysfunction

United States
UCB Pharma SA

Completed

Bioavailability/Bioequivalence Study Between Lacosamide Tablet and Solution for Infusion in Healthy Japanese Subjects

Healthy Volunteers

United Kingdom

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