Search clinical trials for: Bupropion HCl

Total 3115 results

Takeda

Withdrawn

Efficacy of Naltrexone HCl/Bupropion HCl Extended Release Versus Placebo for Treatment of Weight Regain in Participants Post Bariatric Surgery

Weight Regain Post Bariatric Surgery

United States
Alembic Pharmaceuticals Ltd.

Completed

Single Dose Crossover Comparative Bioavailability Study of Bupropion Hcl MR Tablet 300mg

Bioequivalence

Canada
GlaxoSmithKline

Completed

A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Extended-release Bupropion Hydrochloride Tablets in Chinese Healthy Volunteers

Depressive Disorder, Major

China
University of Rochester NCORP Research Base
National Cancer Institute (NCI)

Recruiting

Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors

Be Diagnosed With Cancer and Have Completed Systemic Therapy

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial

Cigarette Smoking-Related Carcinoma

United States
University of Virginia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Diabetes Closed-Loop Project 6 (DCLP6): Fully Automated Closed-Loop Control in Type 1 Diabetes Using Meal Anticipation

Type 1 Diabetes

United States
Rabin Medical Center
Medtronic; GIF

Completed

An Open-label, Two-center, Randomized, Cross-over Study to Evaluate the Safety and Efficacy of Glycemic Control Using Hybrid-closed Loop vs. Advanced Hybrid Closed-loop in Young Subjects With Type 1 Diabetes

Diabetes Mellitus, Type 1

Germany, Israel
Sandoz

Completed

A Relative Bioavailability Study of Bupropion HCI 150 mg Sustained-Release Tablets Under Fasting Conditions

Depression
Rabin Medical Center

Completed

Comparison of Two Closed-Loop Strategies for Glucose Control in Type 1 Diabetes The DREMED Trail- 2

Type 1 Diabetes

Israel
Centre for Addiction and Mental Health
Ontario Ministry of Health and Long Term Care

Completed

STOP Study: Effectiveness of Zyban in a Clinical Population

Smoking Cessation | Cigarette Smoking | Nicotine Addiction

Canada
University of California, Los Angeles

Completed

Bupropion and Cigarette-Related Cues in Smokers

Smoking | Smoking, Tobacco
Mark Eisenberg
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Zyban as an Effective Smoking Cessation Aid for Patients Following an Acute Coronary Syndrome: The ZESCA Trial (ZESCA)

Myocardial Infarction | Smoking | Acute Coronary Syndrome

Canada, United States, Bangladesh, India, Iran, Islamic Republic of, Pakistan, Tunisia
Orexigen Therapeutics, Inc

Terminated

Naltrexone/Bupropion Cardiovascular Outcomes Study

Cardiovascular Diseases | Obesity

United States
Universidad Complutense de Madrid

Completed

One- Versus Two-Stage Aesthetic Crown Lengthening

Patients in Need of Surgical CL in the Anterior Maxillary Sextant for Restorative Purposes
University of California, Los Angeles

Withdrawn

Relapse Prevention in Stimulant Use Disorder

ADHD | Cognitive Function | Relapse | Stimulant Use

United States
St. Joseph's Healthcare Hamilton
Bausch Health, Canada Inc.

Active, not recruiting

A Trial Evaluating the Effectiveness of Contrave in Patients Who Have Weight Recidivism Following Bariatric Surgery (COR-WR)

Obesity

Canada
GlaxoSmithKline

Completed

Lethargic Depression Study

Epilepsy | Major Depressive Disorder (MDD)

United States
St. Joseph's Healthcare Hamilton
Bausch Health, Canada Inc.

Active, not recruiting

Evaluating Contrave for Weight Maintenance in Adults With BMI >= 27 Kg/m2, After 6 Month Behaviour Modification Program. (COR-WM)

Obesity

Canada
Teva Pharmaceuticals USA

Terminated

Bupropion Hydrochloride 300 mg Extended Release Tablets Under Fasting Conditions

Depressive Disorder

United States
University of Kansas Medical Center
National Cancer Institute (NCI)

Completed

Acolbifene in Preventing Cancer in Premenopausal Women at High Risk of Breast Cancer

Breast Cancer

United States
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Bupropion HCI 100 mg Tablets Under Fasting Conditions

Healthy
Thomas Jefferson University

Active, not recruiting

Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use

Head and Neck Squamous Cell Carcinoma | Lung Non-Small Cell Carcinoma

United States
Acologix, Inc.

Unknown

A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch) (AC120-8231)

Uremic Pruritus
Daiichi Sankyo, Inc.

Terminated

Randomized, Double-blind, Active-controlled, Study of Rivoglitazone in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
BioCryst Pharmaceuticals

Completed

Phase II Study of Forodesine in Subjects With Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia (CLL)

United States, Australia
Daiichi Sankyo Co., Ltd.

Completed

Placebo and Active Comparator Controlled Dose Response Study of Rivoglitazone in Type 2 Diabetes (RAISE)

Type 2 Diabetes

China
Daiichi Sankyo Co., Ltd.

Completed

Placebo Controlled Dose-Response Study of Rivoglitazone in Type 2 Diabetes

Type 2 Diabetes

Japan
Orexigen Therapeutics, Inc

Completed

Study to Evaluate the Effect of Naltrexone and Bupropion Extended-Release Combination on Cardiac Repolarization in Healthy Participants

Heart Repolarization

United States
Eli Lilly and Company

Completed

Enzastaurin as Second and Third-Line Treatment for Non-Small Cell Lung Cancer.

Non-Small-Cell Lung Carcinoma

United States
University of Minnesota
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

Varenicline and Smoking Cessation in Schizophrenia (VSCS)

Smoking Cessation | Schizophrenia

United States
Orexigen Therapeutics, Inc

Completed

Zonisamide SR Plus Bupropion SR Combination Therapy in Subjects With Obesity

Obesity

United States
Helsinn Therapeutics (U.S.), Inc

Completed

Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 2)

Non-Small Cell Lung Cancer | Cachexia

Poland, United States, Israel, Russian Federation, Hungary, Australia, United Kingdom
Helsinn Therapeutics (U.S.), Inc

Completed

Anamorelin HCl in the Treatment of Non-Small Cell Lung Cancer-Cachexia (NSCLC-C): An Extension Study (ROMANA 3)

Non-Small Cell Lung Cancer | Cachexia

Poland, Ukraine, United States, Belgium, Spain, Belarus, Slovenia, Serbia, Canada, Russian Federation, Australia, Hungary, Germany, Czechia, France, Israel, Italy
VA Office of Research and Development
Helsinn Therapeutics (U.S.), Inc

Terminated

The Role of Ghrelin in Cancer Cachexia

Cancer Cachexia

United States
Helsinn Therapeutics (U.S.), Inc

Completed

Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1)

Non-Small Cell Lung Cancer | Cachexia

United States, Poland, Ukraine, Belgium, Germany, Spain, Belarus, Slovenia, Serbia, Netherlands, Canada, Russian Federation, Hungary, Czechia, France, Italy
Eli Lilly and Company

Completed

Enzastaurin for Patients With Metastatic Colorectal Cancer

Colonic Neoplasms

Sweden, Denmark
Artax Biopharma Inc
Simbec Research

Completed

Potential Food Effect And Repeated Dosing of AX-024.HCl In Healthy Subjects

Healthy

United Kingdom
Helsinn Therapeutics (U.S.), Inc

Completed

Safety and Efficacy of RC-1291 HCl in Patients With Cancer Related Anorexia and Weight Loss

Cancer Cachexia

United States
Universal Enterprises

Unknown

Bioequivalence of Phenazopyridine HCl in Healthy Volunteers

Human Volunteers

Pakistan
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

Glioma | Astrocytoma | Oligodendroglioma

United States
Abide Therapeutics

Completed

Central Pain Study for ABX-1431

Multiple Sclerosis | Neuromyelitis Optica Spectrum Disorder | Transverse Myelitis | Longitudinally Extensive Transverse Myelitis

United Kingdom
Loyola University

Completed

CATHETER ANALGESIA TRIAL Phenazopyrdine vs. Placebo: a Randomized Controlled Trial (CATH)

Catheter-related Bladder Discomfort

United States
Centre Hospitalier Sud Francilien

Recruiting

Real-world Use of Hybrid Closed Loop in Adolescents and Young Adults 15-25 Years of Age With Type 1 Diabetes (BFHado)

Type1 Diabetes | Adolescents | Young Adults

France
Cortexyme Inc.

Completed

A Multiple Ascending Dose Study of COR388

Alzheimer Disease

United States
Dendreon

Completed

Dose Escalation Study of EC D-3263 HCl in Advanced Solid Tumors

Solid Tumors

United States
Stealth BioTherapeutics Inc.

Not yet recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration
Amicus Therapeutics

Approved for marketing

Physician Initiated Expanded Access Request for Migalastat in Individual Patients With Fabry Disease

Fabry Disease

United States, Australia
Artax Biopharma Inc
Simbec Research; ORION Clinical Services; Packaging Coordinators Inc; Centro de...

Completed

Safety Study of Immune System Modulator for Autoimmune Diseases

Healthy Volunteers

United Kingdom
Helsinn Therapeutics (U.S.), Inc

Completed

Placebo Controlled, Randomized Safety and Efficacy Study of RC-1291 in Cancer Anorexia/Cachexia.

Cancer Cachexia

United States
Atacama Therapeutics

Completed

Exploratory Study to Assess the Efficacy and Safety of TC-5214 in the Treatment of Subjects With Palmar Hyperhidrosis

Palmar Hyperhidrosis

United States

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