Search clinical trials for: daily OAD (metformin and/or sulfonylurea)

Total 233 results

Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Efficacy of ISIS-PTP1BRx in Type 2 Diabetes

Type 2 Diabetes Mellitus | Obese

Argentina, Canada, South Africa
Cinnagen

Unknown

Comparing Efficacy and Safety of CinnaGen-liraglutide Versus Victoza® in Patients With Type II Diabetes

Diabetes Mellitus, Type 2
Assistance Publique - Hôpitaux de Paris

Completed

Effect of GLP-1 on Angiogenesis (ANGIOSAFE 1)

Type 2 Diabetes

France
Dr. Milan Gupta
GlaxoSmithKline

Completed

Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study

Type 2 Diabetes Mellitus

Canada
All India Institute of Medical Sciences, Bhubaneswar
Chemical Resources

Completed

Clinical Evaluation of Fenugreek Seed Extract, a Nutraceutical in Patients With Type- 2 Diabetes

Type-2 Diabetes Mellitus

India
PhaseBio Pharmaceuticals Inc.

Completed

Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM

Type 2 Diabetes Mellitus

United States
Aptabio Therapeutics, Inc.

Completed

Safety, Tolerability, PK and PD of SAD or MAD of APX-115 in Healthy Male Volunteers

Healthy | Safety

France
University of New Mexico

Completed

Metformin Compared to Glyburide in Gestational Diabetes

Gestational Diabetes

United States
All India Institute of Medical Sciences, Bhubaneswar

Completed

Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2

India
GlaxoSmithKline

Completed

AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes

Non-Insulin-Dependent Diabetes Mellitus

Spain, Germany, Belgium, United Kingdom, Ireland, Netherlands, Italy, France, Mexico, Switzerland, Lithuania
Merck Sharp & Dohme LLC

Completed

Evaluation of Low Blood Sugar Events in Participants With Diabetes (MK-0431-402) (NEEDS)

Type 2 Diabetes Mellitus
Medstar Health Research Institute

Completed

Stop Emergency Room Visits for Hyperglycemia Project - District of Columbia (DC) (STEP-DC)

Type 2 Diabetes Mellitus

United States
Takeda

Completed

Efficacy of Pioglitazone in Participants With Inadequately Controlled Type 2 Diabetes Mellitus Treated With Stable Triple Oral Therapy (ADD)

Type II Diabetes Mellitus

Korea, Republic of
Sanofi

Completed

Safety Assessment of Lyxumia (Lixisenatide) and Sulfonylurea as Add-on Treatment to Basal Insulin in Uncontrolled Patients With Type 2 Diabetes Mellitus Who Elect to Fast During Ramadan (LixiRam)

Diabetes Mellitus, Type 2

Israel, India, Kuwait, Turkey
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
GlaxoSmithKline

Completed

RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes (RECORD)

Diabetes Mellitus, Type 2

Spain, Finland, Bulgaria, Belgium, Sweden, Denmark, Germany, Australia, Hungary, Italy, New Zealand, Russian Federation, Ukraine, Estonia, Slovakia, France, Greece, Poland, United Kingdom, Czech Republic, Netherlands, Croatia, Lithu... and more
Boehringer Ingelheim

Withdrawn

Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas

Cardiovascular Diseases | Diabetes Mellitus, Type 2

United States
OPKO Health, Inc.

Completed

A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione

Diabetes Mellitus, Type 2

United States
Meir Medical Center
Clalit Health Services

Unknown

A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin

Diabetes Type 2

Israel
Novo Nordisk A/S

Completed

Efficacy and Safety of Liraglutide Versus Sulphonylurea Both in Combination With Metformin During Ramadan in Subjects With Type 2 Diabetes (LIRA-Ramadan™)

Diabetes Mellitus, Type 2 | Diabetes

India, Israel, Malaysia, South Africa, Algeria, Lebanon, United Arab Emirates
Bristol-Myers Squibb

Completed

A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

United States
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Sulfonylurea (GETGOAL-S)

Diabetes Mellitus, Type 2

United States, Romania, Russian Federation, Germany, Netherlands, Turkey, Bulgaria, India, Taiwan, Czech Republic, Tunisia, Japan, Egypt, Israel, Korea, Republic of, Thailand
Sanofi

Completed

Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled by Metformin (GetGoal-M-Asia)

Type 2 Diabetes Mellitus

China, Hong Kong, Malaysia, Thailand
University of Texas Southwestern Medical Center

Completed

The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study (SIMPLE)

Diabetes Mellitus, Type 2 | Diabetes

United States
Eli Lilly and Company

Completed

A Study Comparing the Effects and Safety of Dulaglutide With Insulin Glargine in Type 2 Diabetes Mellitus (AWARD-CHN2)

Type 2 Diabetes Mellitus

China, Mexico, Korea, Republic of, Russian Federation
Abbott Nutrition

Completed

An Intervention Program to Control Diabetes

Diabetes Mellitus, Type 2

China
Takeda
Eli Lilly and Company

Completed

Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone.

Diabetes Mellitus

Denmark, Iceland, Norway, Sweden
University of Cape Town
Radboud University Medical Center; University of Stellenbosch; Foundation for... and other collaborators

Recruiting

Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19

HIV Infections | COVID-19 | Tuberculosis

South Africa, Zambia, Zimbabwe
Fudan University

Recruiting

Metformin and Insulin to Pancreatic Cancer Related Diabetes (Type 3c)

Diabete Mellitus | Pancretic Cancer

China
Xiang Guang-da

Unknown

Metformin Induces a Dietary Restriction-like State in Human

Aging | Metformin | Overweight Subjects

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Retrospective Analysis for Patients With Metabolic Syndrome

Metabolic Syndrome

China
Khyber Medical University Peshawar

Completed

Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome (PCOS)

PCOS

Pakistan
Kaiser Permanente
National Institute on Drug Abuse (NIDA)

Recruiting

Mobile Intervention for Simultaneous Alcohol and Marijuana Use in Young Adults (SAFERR)

Alcohol Drinking | Cannabis Use

United States
Government Dental College and Research Institute...

Completed

PRF+1% MF for Class II Mandibular Furcation Defects

Furcation Defects

India
University Hospital, Basel, Switzerland

Completed

L-citrulline and Metformin in Duchenne's Muscular Dystrophy

Duchenne's Muscular Dystrophy (DMD)

Switzerland
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of FluarixTM Vaccine in Children Who Have Previously Been Vaccinated With PandemrixTM

Influenza

Finland
KeyBioscience AG
Nordic Bioscience A/S

Completed

Study to Evaluate the Efficacy and Safety of KBP-042 in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

Denmark, Czechia, Poland, Moldova, Republic of, Romania, United Kingdom
Beth Israel Deaconess Medical Center
American Diabetes Association

Completed

Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome

HIV Lipodystrophy

United States
Third Military Medical University

Completed

Liraglutide Improve Cognitive Function in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

China
Federico II University

Unknown

Prevention of Thrombosis Recurrence in Patients With Low Circulating Levels of Antithrombin.

Venous Thrombosis

Italy
University Hospital, Lille

Not yet recruiting

Influence of Preprandial Metformin Administration on Carbohydrate Absorption (METTIME)

Type2 Diabetes | Impaired Glucose Tolerance
University Hospital "Sestre Milosrdnice"
University of Zagreb School of Medicine

Not yet recruiting

The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients

Overweight | Type 2 Diabetes | Disordered Eating Behaviors

Croatia
Centre Hospitalier Universitaire Vaudois

Completed

Safety of Metformin in Pregnancy

Pregnancy | Pregestational Diabetes | Polycystic Ovary Syndrom
University of Toronto
University of Saskatchewan; Saskatchewan Food Industry Development Center

Recruiting

Impact of Pea, Lentil and Oat Flour Particle Size on Glycemic Response in Healthy Adults (PLO)

Obesity | Malnutrition; Diabetes | Malnutrition; Protein

Canada
Mike O'Callaghan Military Hospital

Terminated

Cinnamon Bark, Water-Soluble Cinnamon Extract, and Metformin for Treatment of Type 2 DM.

Diabetes

United States
Seoul National University Bundang Hospital

Completed

Therapeutic Efficacy of Triple Combination in Drug-naïve Korean Type 2 Diabetic Patients

Type 2 Diabetes

Korea, Republic of
Metabolic Center of Louisiana Research Foundation
Amylin Pharmaceuticals, LLC.

Completed

Exenatide and Metformin Therapy in Overweight Women With PCOS

Polycystic Ovary Syndrome

United States
Takeda

Completed

Efficacy of Pioglitazone and Fortamet Combination Therapy in Subjects With Type 2 Diabetes

Diabetes Mellitus
Uppsala University
Uppsala University Hospital

Active, not recruiting

Delayed SLND for Patients With Breast Cancer Undergoing Primary Systemic Treatment (MagNeo)

Breast Cancer | Chemotherapy Effect | Sentinel Lymph Node

Sweden
Novartis Pharmaceuticals

Completed

Vildagliptin/Metformin in T2DM Patients Starting Basal Insulin (ADDONIS)

Type 2 Diabetes Mellitus (T2DM)

France

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