Search clinical trials for: donepezil (Aricept)

Total 337 results

Eisai Inc.
Eisai Limited

Completed

Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease

Alzheimer's Disease

United States
University Hospital, Lille
Innovative Medicines Initiative

Completed

Prediction of Cognitive Properties of New Drug Candidates for Neurodegenerative Diseases in Early Clinical Development (PharmacogWP3)

Alzheimer Disease | Battery

France
Corium, Inc.

Completed

A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept®

Alzheimer Disease

United States
Eisai Inc.
Pfizer

Withdrawn

Evaluating The Impact Of Donepezil Hydrochloride (Aricept) On Behavioral And Psychological Symptoms In Patients With Severe Alzheimer's Disease

Severe Alzheimer's Disease

United States
Pfizer

Completed

A Randomized, Placebo-Controlled Trial to Examine the Efficacy of Oral Donepezil in Subjects With MCI

Alzheimer's Disease

United States
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study for Donepezil Hydrochloride 10 mg Tablets Under Fasting Condition

Healthy

India
Eisai Inc.
Eisai Co., Ltd.

Completed

Efficacy and Safety of Donepezil Hydrochloride (Aricept) in Vascular Dementia

Vascular Dementia

Philippines
Dr. Reddy's Laboratories Limited

Completed

Bioequivalence Study for Donepezil Hydrochloride Tablets 10 mg Under Fed Condition

Healthy

India
Pfizer

Completed

Effect of Aricept on Biomarkers (Acetylcholine, sAPP Alpha) In Cerebrospinal Fluid

Dementia | Alzheimer's Disease

United States
Samsung Medical Center
Eisai Korea Inc.

Completed

Clinical Trial of Donepezil Between the Patients With Alzheimer's Disease and Mixed Dementia

Dementia | Alzheimer's Disease

Korea, Republic of
Merck Sharp & Dohme LLC

Unknown

Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)

Mild Cognitive Impairment | Alzheimer's Disease
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10

Cognitive Dysfunction | Down Syndrome

United States
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17

Cognitive Dysfunction | Down Syndrome

United States
Eisai Inc.

Completed

An Evaluation Of The Efficacy And Safety Of Donepezil Hydrochloride (E2020) In Migraine Prophylaxis

Migraine Headache

United States
Eisai Inc.
Pfizer

Terminated

Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial

Down Syndrome

United States
Stanford University

Completed

An Open-Label Trial of Donepezil in Fragile X Syndrome

Fragile X Syndrome

United States
Teva Pharmaceuticals USA

Completed

10 mg Donepezil Hydrochloride Orally Disintegrating Tablets Under Non-Fasting Conditions

Healthy

United States
Samsung Medical Center
Eisai Korea Inc.

Completed

Clinical Trial of Donepezil Between the Naive Group and the Switching Group

Dementia | Alzheimer's Disease

Korea, Republic of
Eisai Inc.

Completed

A 28-Week Open Label Extension Study Evaluating Safety and Tolerability of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment

Mild Cognitive Impairment

United States
Eisai Co., Ltd.

Completed

A Double-blind Study of E2020 (Donepezil Hydrochloride) in Patients With Dementia With Lewy Bodies (DLB) (Study E2020-J081-431)

Dementia With Lewy Bodies (DLB)

Japan
Lawson Health Research Institute

Completed

Donepezil and the Risk of Falls in Seniors With Cognitive Impairment

Mild Cognitive Impairment (MCI) | Gait | Falls | Balance

Canada
Eisai Co., Ltd.

Completed

A Study of Donepezil Hydrochloride in Patients With Dementia Associated With Cerebrovascular Disease

Dementia Associated With Cerebrovascular Disease

Korea, Republic of
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).

Dementia With Lewy Body Disease

Japan
Shanghai Synergy Pharmaceutical Sciences Co., Ltd.

Completed

Safety and Pharmacokinetic of Donepezil Pamoate in Healthy Subjects

AD

China
Vanderbilt University

Completed

Donepezil and Brain Activity Patterns in Those at Risk For Alzheimer's Disease

Alzheimer's Disease

United States
Pfizer

Terminated

Observational Study Of Donepezil In Routine Clinical Practice

Alzheimer's Disease
Eisai Inc.
Eisai Limited

Completed

Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment

Attention Impairment

United States, Netherlands, France, Spain, United Kingdom, Germany, Argentina, Canada, Australia, Chile
Eisai Inc.
Pfizer

Completed

The Effectiveness And Safety Of Donepezil Hydrochloride (E2020) In Subjects With Mild To Severe Alzheimer's Disease Residing In An Assisted Living Facility

Mild to Severe Alzheimer's Disease

United States
Asan Medical Center
Seoul St. Mary's Hospital; Seoul National University Bundang Hospital; Eisai... and other collaborators

Completed

Optimal Dose Escalation Strategy to Successful Achievement of High Dose Donepezil 23mg (ODESA)

Alzheimer's Disease

Korea, Republic of
Teva Pharmaceuticals USA

Completed

10 mg Donepezil Hydrochloride Orally Disintegrating Tablets Under Fasting Conditions.

Healthy

United States
Corium, Inc.

Completed

Crossover Pharmacokinetic (PK) Study of 5 and 10 mg Corplex™ Donepezil TDS Compared to 10 mg Aricept® in Healthy Volunteers

Healthy Subjects

United States
Duke-NUS Graduate Medical School
GlaxoSmithKline

Completed

fMRI-behavioral Study of Cholinergic Augmentation With Donepezil in Healthy Sleep Deprived Adults

Sleep Deprivation

Singapore
Pfizer

Completed

A Study of the Efficacy and Safety of Aricept in Patients With Severe Alzheimer's Disease Who Are Living in Skilled Nursing Homes

Alzheimer Disease

Sweden
Beth Israel Deaconess Medical Center
National Institute on Aging (NIA)

Completed

Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period (SHARP)

Delirium

United States
Stanford University
National Institute of Mental Health (NIMH); Autism Speaks

Completed

Randomized Controlled Study of Donepezil in Fragile X Syndrome

Fragile X Syndrome

United States
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study of ABT-384 in Subjects With Mild-to-Moderate Alzheimer's Disease

Alzheimer's Disease

Russian Federation, South Africa, Ukraine, United Kingdom
Teva Pharmaceuticals USA

Completed

Donepezil 10 mg Tablets Under Fed Conditions

Healthy

Canada
Teva Pharmaceuticals USA

Completed

Donepezil 10 mg Tablets Under Fasting Conditions

Healthy

Canada
Eisai Korea Inc.

Terminated

Correlation Between Regional Brain Volume and Response to Donepezil Treatment in AD Patients

Alzheimer's Disease

Korea, Republic of
Eunice Kennedy Shriver National Institute of Child...

Unknown

Enhancing Rehabilitation After Stroke (Enhance)

Ischemic Stroke

United States
AstraZeneca

Completed

The Effect of Cognitive Function as Measured by Repeated Cognitive Measures After 12 Weeks Treatment With Donepezil

Alzheimer's Disease

Peru, Poland, Canada, South Africa
Ever Neuro Pharma GmbH
acromion GmbH

Completed

Comparative Study to Test Safety and Efficacy of Neurotrophic and Cholinergic Treatment of Alzheimer's Disease (Combi)

Alzheimer Disease

Spain
Kessler Foundation
Pfizer

Unknown

Aricept to Improve Functional Tasks in Vascular Dementia

Stroke | Vascular Dementia | Memory Deficits

United States
Baylor College of Medicine
Albert Einstein Healthcare Network; Indiana University; Spaulding Rehabilitation... and other collaborators

Active, not recruiting

Multicenter Evaluation of Memory Remediation After TBI With Donepezil (MEMRI-TBI-D)

Traumatic Brain Injury | Memory Deficits

United States
Icure Pharmaceutical Inc.

Completed

A Multinational, Multi-center, Randomized, Double-blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer's Disease

Alzheimer Disease

Korea, Republic of
Corium, Inc.

Completed

A Bioequivalence Study of Corplex™ Donepezil Transdermal Delivery System Compared to Aricept®

Alzheimer's Disease

United States
Dong-A ST Co., Ltd.

Completed

Single-ascending Dose Phase 1 Clinical Trial to Evaluate the Safety and PK of DA-5207 TDS in Healthy Adults

Healthy

Korea, Republic of
Eisai Inc.
Pfizer

Completed

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome

Down Syndrome

United States
Sunnybrook Health Sciences Centre
University of Toronto

Completed

Impact of Cholinesterase Inhibitors on Driving Ability in Healthy Older Adults

Mental Health | Geriatrics

Canada
University of Pittsburgh
National Institute of Mental Health (NIMH)

Completed

Donepezil HCl & Cognitive Deficits in Autism

Autistic Disorder

United States

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