Search clinical trials for: Estetrol

Total 83 results

Pantarhei Bioscience

Completed

Study to Evaluate 3 Dosages of Estetrol After 28 Days Administration in Healthy Postmenopausal Women

Healthy

Netherlands
Estetra
Quotient Clinical

Completed

Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol

Menopause | Contraception

United Kingdom
Pantarhei Oncology B.V.

Completed

Evaluation of Safety and Efficacy of Estetrol in Healthy Men

Prostatic Neoplasms

Netherlands
Donesta Bioscience
SynteractHCR

Completed

E4Relief (Response to Estetrol in Life Improvement for MEnopausal-associated Hot Flushes)

Hot Flushes

Belgium
Estetra

Completed

Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers

Menopause | Contraception

Bulgaria
Pantarhei Oncology B.V.

Completed

Assessment of Safety and Efficacy of Estetrol in Postmenopausal Women With Advanced Estrogen Receptor Positive (ER+) Breast Cancer

Breast Neoplasms

Germany
Estetra

Recruiting

Estetrol for the Treatment of Female Sexual Arousal Disorder in Postmenopausal Women

Sexual Dysfunction, Physiological

United States
Pantarhei Bioscience

Completed

Preoperative Estetrol in Breast Cancer

Breast Cancer

Austria
Estetra
ICON Clinical Research

Completed

Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort)

Vasomotor Symptoms | Menopausal Symptoms

United States, Canada
NEURALIS s.a.

Active, not recruiting

Estetrol (E4) for the Treatment of Patients With Confirmed SARS-COV-2 Infection

Covid19

Belgium, Hungary, Russian Federation, Poland
Pantarhei Oncology B.V.

Completed

Evaluation of Effects of Estetrol on Testosterone Suppression and Quality of Life in Prostate Cancer Patients Treated With an LHRH Agonist.

Prostatic Neoplasm

Netherlands
Pantarhei Bioscience

Completed

Feasibility Study Into the Contraceptive Effect of Estetrol

Healthy

Netherlands
Donesta Bioscience

Completed

Effect of Food on the Bioavailability of 30 mg Estetrol (E4) Tablet in Healthy Postmenopausal Female Volunteers

Food-effect

Bulgaria
Chong Kun Dang Pharmaceutical

Completed

CKD-391 DDI : Atorvastatin and Ezetimibe in Healthy Volunteers

Healthy

Korea, Republic of
University of Palermo
University of Roma La Sapienza

Completed

The Use of Drospirenone/Estetrol in Random Start Rapid Endometrial Preparation

Endometrial Polyp | Endometrial Diseases

Italy
Estetra

Completed

E4/DRSP Single and Multiple Dose PK and Early QT Study

Contraception
Estetra

Completed

Effect of Estetrol Monohydrate (E4) on QTc Interval

Prolonged QTc Interval

United States
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
McGill University Health Centre/Research Institute...

Not yet recruiting

Estetrol/Drospirenone to Reduce the Average Size of Endometriomas (ERASE)

Endometrioma | Ovarian Endometrioma

Canada
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
Estetra
ICON Clinical Research

Active, not recruiting

Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)

Vasomotor Symptoms | Menopausal Symptoms

Spain, United States, Argentina, Lithuania, Poland, Italy, Hungary, United Kingdom, Romania, Czechia, Brazil, Canada, Russian Federation, Slovakia
Stanford University
Piper Biosciences, Inc.

Completed

Impact of Plant Sterol Supplement on LDL-C Lowering in Low-to-Moderate Risk South Asian Patients

Cardiovascular Risk Factor

United States
University of Manitoba

Completed

Genetic Basis for Heterogeneity in Response of Plasma Lipids to Plant Sterols

Hyperlipidemia

United States, Canada
University of Helsinki
University of Eastern Finland

Completed

The Influence of Dietary Plant Sterols and Plant Stanols on Cholesterol and Plant Sterol Levels in Atheromatous Plaques

Atherosclerosis

Finland
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
Piper Biosciences, Inc.

Unknown

Impact of a Chewable Plant Sterol Supplement on LDL-C in A Real-World Setting

Hyperlipidemia

United States
I.M. Sechenov First Moscow State Medical University

Completed

Probiotics and Hemodynamic Changes in Cirrhosis (PrBHCCir)

Cirrhosis

Russian Federation
University of Palermo
University of Roma La Sapienza

Completed

The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation

Endometrial Polyp | Endometrial Diseases

Italy
Maastricht University Medical Center
Unilever R&D

Completed

Gastric Emptying and Gallbladder Motility Study

Gastric Emptying

Netherlands
Estetra

Completed

Cycle Control Assessment of a Combined Oral Contraceptive Containing Estetrol and a Progestin P1 or P2 (FIESTA)

Contraception

Finland
Inner Mongolia Yili Industrial Group Co., Ltd

Completed

The Effect of Shuhua Milk Fortified With Plant Sterol Esters on Serum Cholesterol in Human

Hypercholesterolemia

China
French Cardiology Society
Fondation Coeur et Artères

Withdrawn

Effect of Phytosterols Enriched Products Consumption on Carotid Artery Artherosclerotic Plaque (PHYTOPLAQUES)

Hypercholesterolemia

France
NVP Healthcare

Completed

to Investigate the Pharmacokinetic Interactions and Safety Between Rosuvastatin and Ezetimibe in Healthy Male Volunteers (NVP-1205)

Healthy
Estetra

Completed

Effect of Food on the Bioavailability of 15 mg Estetrol/3 mg Drospirenone Tablets in Healthy Female Volunteers

Contraception
University of Manitoba
WhiteWave Foods, Inc.

Completed

Efficacy of Sterol-Fortified Low Fat Soy Beverage on Cholesterol Metabolism, Inflammation and Oxidative Status in Humans - Study II

Hypercholesterolemia

Canada
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Long Term Effects of Plant Sterol and Stanol Esters (LTS)

Hypercholesterolemia

Netherlands
The George Institute
Peking University

Completed

China Plant Sterol Trial

Cardiovascular Diseases | Hypercholesterolemia

China
Estetra
PRA Health Sciences

Completed

E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - EU/Russia Study

Contraception

Belgium
Ocera Therapeutics, Inc.

Completed

OCR002-SP103 - Oral Immediate Release Study

Cirrhosis

United States
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Phytosterols and Oxyphytosterol Concentrations

Normocholesterolemic

Netherlands
University of California, San Diego

Completed

Ezetimibe Versus Placebo in the Treatment of Non-alcoholic Steatohepatitis

Non Alcoholic Steatohepatitis

United States
University Hospital, Saarland

Unknown

Differential Effects of a Diet Supplementation With Plant Sterol Esters on Human Monocytes (PSE-MO)

Hyperlipidemia

Germany
Estetra
PRA Health Sciences

Completed

E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - United States/Canada Study

Contraception

United States, Canada
Medical University of Graz

Completed

Fluvastatin 80 mg Ret. vs Combination With Ezetimibe 10 mg in Patients With High Cardiovascular Risk

Hypercholesterolemia

Austria
Odense University Hospital

Completed

Ezetimibe In Addition To Atorvastatin Therapy On The Plaque Composition In Patients With Acute Myocardial Infarction. (OCTIVUS)

ST-Segment Elevation Myocardial Infarction

Denmark
Maastricht University Medical Center
Unilever R&D; Raisio Group; BASF

Unknown

Plant Sterols and Plant Stanols and Liver Inflammation

Non-Alcoholic Fatty Liver Disease

Netherlands
Organon and Co

Completed

Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)

Hypercholesterolemia | Coronary Heart Disease
Laval University

Completed

Effects of Selective Inhibition of Cholesterol Absorption With Ezetimibe on Intestinal Cholesterol Homeostasis in Dyslipidemic Men With Insulin-resistance - a Pilot Study (EZEmRNA)

Metabolic Syndrome X

Canada
Cao Yu

Recruiting

Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Therapeutic Equivalency

China
The Affiliated Hospital of Qingdao University

Completed

Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects

Hyperlipidemias

China

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