Search clinical trials for: interleukin-1

Total 15795 results

Tanta University

Completed

IL- 6 Gene (174G/C) Single Nucleotide Polymorphism as an Indicator of COVID-19 Severity in Egyptian Patients

Covid19

Egypt
Radboud University Medical Center

Unknown

The Effect of Anakinra on Insulin Secretion

Glucose Intolerance | Diabetes Mellitus Type 2 | Impaired Insulin Secretion

Netherlands
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Withdrawn

Anti-IL-1 Treatment in Children Diabetic Keto-Acidosis (DKA) at Diagnosis of Type 1 Diabetes

Type I Diabetes

United States
Radboud University Medical Center

Unknown

Effect of Anakinra on Insulin Sensitivity in Type 1 Diabetes Mellitus

Diabetes Mellitus

Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/II

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Cord Blood Transplant Recipient

United States
National Cancer Institute (NCI)

Completed

Feasibility Study of Interleukin 1-Alpha With Ifosfamide, CBDCA, and Etoposide With Autologous Bone Marrow Transplant in Metastatic Carcinoma and Lymphoma

Lymphoma | Testicular Neoplasms | Breast Neoplasms | Neoplasm Metastasis

United States
Kanuni Sultan Suleyman Training and Research Hospital

Completed

GDM Patients and Serum Amyloid A and Interleukin-1 (IL-1) Receptor Antagonist

Gestational Diabetes

Turkey
Virginia Commonwealth University
American Heart Association

Completed

Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection Fraction

Heart Failure

United States
Federal Research Institute of Pediatric Hematology...

Completed

IL-1 Receptor Inhibitor for Granulomatous Complications in Patients With Chronic Granulomatous Disease

Chronic Granulomatous Disease

Russian Federation
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy (KIN-ATTACK-FMF)

FMF

France
Beijing Tongren Hospital

Completed

A Study of CM310 in Patients With Uncontrolled Seasonal Allergic Rhinitis (MERAK)

Allergic Rhinitis

China
National Institute of Allergy and Infectious Diseases...

Terminated

A Pilot Study Using Anakinra/Kineret for the Treatment of Patients With Severe Atopic Dermatitis

Eczema | Atopic Dermatitis | Allergic Disease | Anakinra | Kineret

United States
National Cancer Institute (NCI)

Completed

Anakinra in Treating Patients With Metastatic Cancer Expressing the Interleukin-1 Gene

Unspecified Adult Solid Tumor, Protocol Specific

United States
Karolinska Institutet

Completed

Anakinra in Myositis

Dermatomyositis | Polymyositis | Inclusion Body Myositis

Sweden
National Institute of Neurological Disorders and...

Completed

Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple Sclerosis

Multiple Sclerosis

United States
National Institute of Arthritis and Musculoskeletal...

Completed

Anakinra for Behcet s Disease

Immune System Diseases | Autoimmune Connective Tissue Disorder

United States
Azienda Ospedaliero, Universitaria Ospedali Riuniti

Recruiting

Therapy Management in Patients Treated With Anakinra Due to Recurrent Pericarditis

Recurrent Pericarditis

Italy
Virginia Commonwealth University

Recruiting

The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART) (AID-HEART)

Heart Failure

United States
Assistance Publique - Hôpitaux de Paris

Completed

CORIMUNO-ANA: Trial Evaluating Efficacy Of Anakinra In Patients With Covid-19 Infection (CORIMUNO-ANA)

Corona Virus Infection

France
National Institute of Neurological Disorders and...
Johns Hopkins University

Terminated

Anakinra, A Recombinant Human IL-1 Receptor Antagonist for Neuroinflammation in HIV-1 Infection

HIV Infections | Neurologic Disorders

United States
Virginia Commonwealth University
National Institutes of Health (NIH); National Center for Research Resources...

Completed

Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Heart Failure

Heart Failure

United States
Thomas Marron

Recruiting

Dupilumab_Metastatic NSCLC

Metastatic Non-small Cell Lung Cancer

United States
Swedish Orphan Biovitrum

Completed

Long-term Safety Study of Kineret® in Patients With Systemic Juvenile Idiopathic Arthritis (SJIA)

Still Disease, Juvenile Onset

Italy
Virginia Commonwealth University

Terminated

Treatment of Acute Pericarditis With Anakinra

Acute Pericarditis

United States
University of Utah

Completed

Interleukin-1 Receptor Antagonist for the Treatment of Heart Failure in Patients With Left Ventricular Assist Devices

Heart Failure

United States
Assistance Publique - Hôpitaux de Paris
Swedish Orphan Biovitrum

Completed

Anakinra and Kawasaki Disease (KAWAKINRA)

Children | Kawasaki Disease

France
Andrea Vambutas
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease

Sensorineural Hearing Loss | Autoimmune Inner Ear Disease

United States
Andrea Vambutas

Terminated

Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing Loss (SSNHL)

Hearing Loss, Sudden

United States
Massimo Imazio

Completed

AnakInRa for Treatment of Recurrent Idiopathic Pericarditis (AIRTRIP) (AIR TRIP)

Idiopathic Recurrent Pericarditis

Italy
Michelle Hernandez, MD
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Effect of Interleukin-1 Receptor Antagonist on Inhalation of 20,000 EU Clinical Ctr Reference Endotoxin in Normal Volunteers (Kintox)

Healthy Control Subjects

United States
Amgen

Completed

Evaluation of the Efficacy of Combination Treatment With Anakinra and Pegsunercept in Improving Rheumatoid Arthritis

Rheumatoid Arthritis
University Hospital, Basel, Switzerland

Recruiting

Hyperinsulinemia in Prediabetes Mediated by Interleukin-1β (Hyper-PreDIL)

PreDiabetes | Hyperinsulinemia

Switzerland
Oxford University Clinical Research Unit, Vietnam
Wellcome Trust; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

Recruiting

Anakinra in Dengue With Hyperinflammation ( AnaDen )

Cytokine Storm | Dengue | Severe Dengue | Macrophage Activation Syndrome | Anakinra | Dengue With Warning Signs | Anti-inflammatory Agents | Hyperinflammatory Syndrome | Immuno-modulation

Vietnam
Radboud University Medical Center
Dutch Heart Foundation

Recruiting

Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic Stroke (ACTION)

Intracerebral Hemorrhage

Netherlands
Virginia Commonwealth University

Completed

Interleukin-1 Blockade In Recently Decompensated Heart Failure - 2 (REDHART2)

Inflammation | Heart Failure, Systolic

United States
Rennes University Hospital

Terminated

Treatment of Refractory Hemochromatosis Rheumatism by Anakinra: a Preliminary Phase II Study (THERA)

Refractory Hemochromatosis Rheumatism

France
National Institute of Arthritis and Musculoskeletal...

Terminated

Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease

Nervous System Malformations | Urticaria | Papilledema | Arthropathy, Neurogenic

United States
Heidelberg University

Recruiting

A Study to Evaluate Safety and Efficacy of Subcutaneous Administration of Anakinra in Patients With CF (ANAKIN)

Cystic Fibrosis, 10011762

Germany
Memorial Sloan Kettering Cancer Center

Active, not recruiting

A Study of Anakinra to Prevent or Treat Severe Side Effects for Patients Receiving CAR-T Cell Therapy

B-Cell Lymphoma | B-cell Non Hodgkin Lymphoma | B Cell ALL

United States
Lynda E Polgreen
Swedish Orphan Biovitrum; Cure Sanfilippo Foundation

Completed

Open-label Study of Anakinra in MPS III

Mucopolysaccharidosis III

United States
Monash Medical Centre
Monash University; University of Auckland, New Zealand; Hudson Institute of Medical... and other collaborators

Active, not recruiting

Anakinra for Preterm Infants Pilot

Inflammation | Prematurity; Extreme

Australia, New Zealand
University of California, San Diego
Boston Children's Hospital; Cedars-Sinai Medical Center

Completed

Anakinra in Infants and Children With Coronary Artery Abnormalities in Acute Kawasaki Disease

Kawasaki Disease

United States
National Institute of Arthritis and Musculoskeletal...

Completed

Anakinra for Inflammatory Pustular Skin Diseases

Palmoplantar Pustulosis | Pustular Psoriasis | Sneddon-Wilkinson | Acrodermatitis Continua of Hallopeau

United States
Swedish Orphan Biovitrum

Completed

Kineret in the Treatment of Rheumatoid Arthritis

Rheumatoid Arthritis

Germany
Amgen

Completed

Juvenile Rheumatoid Arthritis

Juvenile Chronic Arthritis
Swedish Orphan Biovitrum
CMIC Co, Ltd. Japan

Active, not recruiting

A Study of Anakinra in Japanese Patients With Still's Disease (SJIA and AOSD)

Still's Disease, Adult-Onset | Still's Disease, Juvenile Onset

Japan
Virginia Commonwealth University

Withdrawn

Interleukin-1 Blockade for the Treatment of Heart Failure in Patients With Advanced Chronic Kidney Disease (E-HART)

Chronic Kidney Diseases | Heart Failure, Systolic | Renal Disease, End Stage
Duke University

Completed

Study to Prevent Cartilage Damage Following Acute Knee Injury.

Knee Injury

United States
Amgen

Completed

Anakinra (Kineret®) in Combination With Disease Modifying Anti-Rheumatic Drugs (DMARDS) in Subjects With Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis
Sohag University

Not yet recruiting

Evaluation of Serum Interleukin-15 and Interleukin-22 Levels in Patients With Non-segmental Vitiligo

Vitiligo

Search clinical trials for: interleukin-1

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