Search clinical trials for: Lacosamide

Total 102 results

UCB BIOSCIENCES, Inc.
Pharmaceutical Research Associates

Completed

A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications (VALOR)

Epilepsy

United States, Australia, Belgium, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
Seoul National University Hospital
Dongsan Medical Center; Konkuk University

Completed

Efficacy and Safety of Rapid Titration Protocols of Lacosamide

Focal Epilepsy

Korea, Republic of
University of California, San Francisco
San Francisco VA Health Care System

Completed

Pilot Human Lab Study of Lacosamide in Alcohol Use Disorder (AUD) (ACGT)

Alcohol Use Disorder

United States
UCB Biopharma S.P.R.L.

Completed

A Study to Investigate the Bioequivalence of Lacosamide Tablet (200mg) and Syrup (10mg/ml) in Healthy Chinese Male Subjects

Healthy Male Volunteers

China
UCB Biopharma S.P.R.L.

Completed

A Study to Demonstrate the Bioequivalence of Lacosamide Tablets and Dry Syrup in Healthy Male Japanese Subjects

Healthy Volunteers

United Kingdom
UCB Pharma

Completed

An Open-label follow-on Trial to Assess the Long-term Safety and Efficacy of Oral SPM 927 in Subjects With Diabetic Neuropathy

Painful Diabetic Neuropathy
Overseas Pharmaceuticals, Ltd.
Beijing Capton Pharmaceutical Technology Development Co., LTD

Not yet recruiting

An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.

Epilepsy

China
UCB Pharma SA
UCB Japan Co. Ltd.

Completed

A Trial to Evaluate the Efficacy and Safety of Adjunctive Therapy With Lacosamide in Adults With Partial-Onset Seizures

Epilepsy | Partial Onset Seizures

China, Japan
UCB Pharma SA

Completed

Bioavailability/Bioequivalence Study Between Lacosamide Tablet and Solution for Infusion in Healthy Japanese Subjects

Healthy Volunteers

United Kingdom
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures (LENS)

Epilepsy | Electroencephalographic Neonatal Seizures

United States, Australia, Canada
UCB BIOSCIENCES, Inc.

Completed

Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic Seizures (VALUE)

Epilepsy

United States, Australia, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
UCB Biopharma S.P.R.L.

Completed

A Study to Investigate the Bioequivalence of Lacosamide 200mg Administered as Intravenous Solution and Oral Tablet in Healthy Chinese Male Subjects

Healthy Male Chinese Volunteers

China
UCB BIOSCIENCES, Inc.

Completed

Determine Safety and Efficacy of Long-term Oral Lacosamide in Patients With Partial Seizures

Partial Epilepsies

United States
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Unknown

A Real World Study on the Efficacy and Safety of Lacosamide as Add-on Therapy for Focal-onset Epilepsy

Epilepsy | Focal-Onset Seizure

China
UCB Pharma

Completed

A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy

Diabetic Neuropathy

United States
UCB Pharma

Terminated

Trial to Assess Efficacy and Safety of Lacosamide in Subjects With Osteoarthritis of the Knee

Osteoarthritis

Poland, Germany, Romania, Hungary, United Kingdom, Sweden, Czechia
Le Bonheur Children's Hospital

Completed

IV Lacosamide: The Safety of Intravenous Lacosamide

Epilepsy

United States
UCB Pharma

Completed

To Determine Tolerability and Efficacy of Long-term Oral Lacosamide in Patients With Partial Seizures

Partial Epilepsies

United States, Poland, United Kingdom, Switzerland, Hungary, Germany, Sweden, Lithuania
UCB BIOSCIENCES, Inc.

Completed

Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset Seizures

Partial Epilepsies | Partial Onset Seizures

United States
UCB BIOSCIENCES GmbH

Completed

Study to Evaluate the Pharmacokinetics, Safety, Tolerability of Single Dose Lacosamide in Subjects With Renal Impairment Compared to Healthy Subjects

Healthy | Renal Impairment

Germany
University Hospital Schleswig-Holstein

Completed

Lacosamid-i.v.-Register (LCM)

Epilepsy With Partial Onset Seizures With or Without Secondary Generalization

Germany
UCB Pharma

Completed

A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).

Postherpetic Neuralgia
UCB Pharma

Completed

A Trial to Investigate Safety and Efficacy of SPM927 in Painful Diabetic Neuropathy

Painful Diabetic Neuropathy
Instituto de Investigacion Sanitaria La Fe

Completed

Observational Retrospective Study of Effectivity and Tolerability in Patients With Lacosamide Medication

Epilepsy

Spain
UCB Japan Co. Ltd.
Parexel

Completed

Open-label Study to Evaluate the Safety and Tolerability of iv Lacosamide in Japanese Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
UCB BIOSCIENCES, Inc.

Completed

Study to Assess the Long-term Safety of Oral Lacosamide in Subjects With Partial-onset Seizures

Partial Epilepsies | Partial Onset Seizures

United States
Brigham and Women's Hospital

Completed

Add on Lacosamide Versus High Dose Monotherapy

Epilepsy

United States
University of Alabama at Birmingham
UCB Pharma

Terminated

A Pilot Study of NSICU Assessment of Seizure Prophylaxis With Lacosamide

Traumatic Brain Injury

United States
Xiangya Hospital of Central South University

Recruiting

Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy

Epilepsy | Alzheimer Disease 3

China
Aatif Husain
UCB Pharma

Completed

Intravenous Lacosamide Compared With Fosphenytoin in the Treatment of Patients With Frequent Nonconvulsive Seizures (TRENdS)

Nonconvulsive Seizures

United States
Lawson Health Research Institute
UCB Pharma GmbH

Terminated

Comparative Trial of IV Lacosamide Versus Phenytoin for Seizure Management

Seizures

Canada
Kafrelsheikh University

Recruiting

Lacosamide Versus Topiramate in Migraine

Migraine Disorders

Egypt
Laniado Hospital

Not yet recruiting

Addition of Dydrogesterone to the Luteal Phase Support After Fresh Embryo Transfer

Infertility | IVF

Israel
Tanta University

Recruiting

Effect of Silymarin in Metastatic Colorectal Cancer Patients

Metastatic Colorectal Cancer

Egypt
Kafrelsheikh University

Completed

Lacosamide Versus Propranolol in Migraine

Migraine Disorders

Egypt
Liu Yonghong
First Affiliated Hospital Xi'an Jiaotong University; Second Affiliated Hospital... and other collaborators

Enrolling by invitation

Acute Sympotomatic Seizure Secondary to Autoimmune Encephalitis and Autoimmune-associated Epilepsy

Epilepsy | Seizures | Autoimmune Encephalitis

China
Chiba University

Completed

Open-label Clinical Trial of Lacosamide in ALS

Amyotrophic Lateral Sclerosis

Japan
UCB Pharma

Completed

Study Evaluating Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy.

Painful Diabetic Neuropathy

Russian Federation, Austria, Belgium, Bulgaria, Czechia, Finland, France, Germany, Hungary, Italy, Poland, Romania, Serbia, Spain, United Kingdom
Danish Pain Research Center
Odense University Hospital

Terminated

The Effect of Lacosamide in Peripheral Neuropathic Pain

Neuropathic Pain | Neuropathy | Neuropathy, Diabetic | Neuropathy;Peripheral | Neuropathy, Painful

Denmark
Le Bonheur Children's Hospital

Completed

The Safety of Intravenous Lacosamide

Epilepsy

United States
UCB Biopharma S.P.R.L.

No longer available

Compassionate Use Program With Lacosamide in Patients With Partial-onset or Generalized Tonic-clonic Seizures

Epilepsies, Partial
UCB BIOSCIENCES, Inc.

Completed

Trial to Demonstrate the Efficacy and Safety of Conversion to Lacosamide Monotherapy for Partial-onset Seizures (ALEX-MT)

Epilepsy

Austria, United States, Australia, Canada, Denmark, France, Germany, Ireland, Italy, Poland, Puerto Rico, Spain, United Kingdom
UCB Japan Co. Ltd.

Completed

A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
UCB Pharma

Completed

A Study to Investigate the Safety and Efficacy of Lacosamide Added to the Patients Current Therapy in Patients Aged 1 Month to Less Than 18 Years Old With Epilepsy Syndromes Associated With Generalized Seizures.

Epilepsy

United States, France, Hungary, Mexico, Poland
Evan Fertig
UCB Pharma

Completed

Cognitive and Behavioral Effects of Lacosamide

Epilepsy

United States
UCB Pharma

Completed

A Multicenter, Open-label Study to Determine the Effects of Lacosamide on Sleep in Healthy Subjects

Healthy Subjects

United States
UCB BIOSCIENCES, Inc.

Completed

Open-Label Extension Study to Assess the Safety and Seizure Frequency Associated With Lacosamide for Primary Generalized Tonic-Clonic Seizures in Subjects With Epilepsy

Epilepsy

United States
UCB Pharma

Completed

Trial to Assess Long-term Lacosamide (LCM) Monotherapy Use and Safety of LCM Monotherapy and Adjunctive Therapy for Partial-onset Seizures

Epilepsy

United States, Australia, Canada, Denmark, Germany, Italy, Poland, United Kingdom, Spain
UCB Pharma

Completed

Trial to Assess Optimized Dosage of Lacosamide as add-on Therapy in Patients With Partial Onset Seizure (SELF)

Partial Epilepsies

France
UCB Pharma
SCHWARZ BIOSCIENCES GmbH - Part of UCB Group

Completed

A Trial to Assess the Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

Germany

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