Search clinical trials for: oral eflornithine placebo

Total 59225 results

University of Alabama at Birmingham
National Cancer Institute (NCI)

Completed

Neoadjuvant Eflornithine and Bicalutamide Compared With Eflornithine Alone, Bicalutamide Alone, and No Neoadjuvant Therapy in Treating Patients With Localized Prostate Cancer Undergoing Brachytherapy or Radical Prostatectomy

Prostate Cancer

United States
Drugs for Neglected Diseases
Swiss Tropical & Public Health Institute; Ministry of Public Health, Democratic...

Completed

Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic Phase (NECT-FIELD)

Human African Trypanosomiasis

Congo
SWOG Cancer Research Network
National Cancer Institute (NCI); Cancer Prevention Pharmaceuticals, Inc.

Active, not recruiting

S0820, Adenoma and Second Primary Prevention Trial (PACES)

Colorectal Neoplasms

United States
Walter Reed National Military Medical Center

Terminated

Topical Eflornithine for Pseudofolliculitis Barbae: Randomized Controlled Trial

Pseudofolliculitis Barbae

United States
Orbus Therapeutics, Inc.

Recruiting

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma

Glioblastoma | Glioblastoma Multiforme | GBM | Glioblastoma, IDH-wildtype | Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

United States
Thomas E. Ahlering
National Cancer Institute (NCI)

Completed

Eflornithine in Treating Patients At High Risk of Developing Prostate Cancer

Prostate Cancer

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); Cancer Prevention Pharmaceuticals, Inc.

Active, not recruiting

Chemoprevention of Gastric Carcinogenesis

Gastric Cancer | Gastric Intestinal Metaplasia

Honduras, Puerto Rico
National Cancer Institute (NCI)

Completed

Eflornithine in Treating Patients With Bladder Cancer

Bladder Cancer

United States
Cancer Prevention Pharmaceuticals, Inc.

Withdrawn

A Trial of Low Dose Sulindac Combined With Eflornithine in Patients With Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis
Allergan

Completed

Evaluation of Eflornithine on Facial and Forearm Skin

Hirsutism
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Eflornithine to Prevent Skin Cancer in Patients With Previously Treated Early Stage Skin Cancer

Non-melanomatous Skin Cancer
Hordinsky, Maria K., MD

Completed

Effect of 15% Eflornithine Hydrochloride Cream on African-American Males With Pseudofolliculitis Barbae

Pseudofolliculitis Barbae

United States
Giselle Sholler
Beat NB Cancer Foundation; Team Parker for Life

Recruiting

Neuroblastoma Maintenance Therapy Trial (NMTT)

Neuroblastoma

United States, Canada
Bispebjerg Hospital

Completed

Treatment With Topical Eflornithin After Laser Treatment in Women With Facial Hirsutism

Hirsutism

Denmark
VA Office of Research and Development

Active, not recruiting

Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation

Suicidal Ideation

United States
Evelo Biosciences, Inc.

Completed

A Study of EDP1815 in Healthy Participants and Participants With Mild to Moderate Psoriasis and Atopic Dermatitis

Psoriasis | Atopic Dermatitis

United Kingdom
Sao Thai Duong Joint Stock Company
Big Leap Clinical Research Joint Stock Company

Completed

Safety and Efficacy of KOVIR in the Combination Regimen With Background Treatment in COVID-19 Patients (KOVIR) (KOVIR)

COVID-19

Vietnam
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy

United States
Royan Institute

Unknown

The Effect of Simvastatin on Uterine Leiomyoma Development and Growth in Infertile Women

Infertility

Iran, Islamic Republic of
Pulmagen Therapeutics

Completed

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of ADC3680B in Subjects With Partly Controlled Atopic Asthma

Atopic Asthma

United Kingdom
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Completed

Eflornithine to Prevent Cancer in Patients With Barrett's Esophagus

Esophageal Cancer

United States
Georgetown University
National Institutes of Health (NIH)

Recruiting

Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies

Dementia With Lewy Bodies

United States
University of British Columbia
Crohn's and Colitis Canada

Withdrawn

FMT for Remission of Active Ulcerative Colitis in Adults

Inflammatory Bowel Diseases | Ulcerative Colitis

Canada
Giselle Sholler
K C Pharmaceuticals Inc.; USWM, LLC

Available

An Intermediate Expanded Use Trial of DFMO

Embryonal Tumor With Abundant Neuropil and True Rosettes | Medulloblastoma | Neuroblastoma | Medulloepithelioma | Ependymoblastoma | Typical Teratoid Rhabdoid Tumor

United States
Applied Molecular Transport

Active, not recruiting

Study of the Efficacy and Safety of AMT-101 in Subjects With Ulcerative Colitis (LOMBARD)

Ulcerative Colitis

United States, Hungary, Ukraine, Germany, United Kingdom, Belarus, Bulgaria, Canada, France, Georgia, Moldova, Republic of, Poland, Russian Federation, Switzerland
Wockhardt

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of Oral WCK 2349

Pharmacokinetics
Epicentre
Médecins Sans Frontières, France

Terminated

Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, Uganda (NECS)

Trypanosomiasis, African

Uganda
The Mind Research Network

Terminated

Mechanisms of Lorcaserin for Smoking Cessation

Smoking Cessation | Tobacco Use Disorder

United States
National Polytechnic Institute, Mexico

Unknown

Clinical Effect of Dialyzable Leukocyte Extract in Suspected or Confirmed Cases of COVID-19 (FUTURE-T) (FUTURE-T)

COVID-19 | SARS-CoV-2 Infection

Mexico
National Institute on Drug Abuse (NIDA)

Completed

Effects of Cannabis Administration Routes on Human Performance and Pharmacokinetics

Cannabis Use

United States
Estetra
ICON Clinical Research

Completed

Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort)

Vasomotor Symptoms | Menopausal Symptoms

United States, Canada
Johns Hopkins University
Canopy Growth Corporation

Recruiting

Pharmacokinetics and Pharmacodynamics of CHI-914 in Healthy Participants

Behavioral Pharmacology of Cannabis

United States
Harmony Biosciences, LLC

Active, not recruiting

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

Myotonic Dystrophy 1 | Excessive Daytime Sleepiness

United States, Canada
Syntrix Biosystems, Inc.
National Institute on Drug Abuse (NIDA); DF/Net Research

Completed

Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

Diabetic Neuropathies | Neuropathic Pain | Pain, Chronic

United States
Aelis Farma
National Institute on Drug Abuse (NIDA)

Completed

Multiple Ascending Dose to Study the Safety, Tolerability, PK and PD Effects of AEF0117

Healthy Volunteers

United States
EicOsis Human Health Inc.

Recruiting

Safety, Tolerability, and Pharmacokinetics of Multiple Doses of Oral EC5026 in Healthy Subjects

Healthy Subjects

New Zealand
Brigham and Women's Hospital

Completed

DAW1033D in Obstructive Sleep Apnea (OSAstimD)

Obstructive Sleep Apnea (OSA)

United States
Eunice Kennedy Shriver National Institute of Child...

Terminated

Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and Hormones

Amenorrhea | Aplastic Anemia | Menorrhagia

United States
University of Oxford
Novo Nordisk A/S

Recruiting

A Study of Cardiovascular Events iN Diabetes Plus (ASCEND PLUS)

Diabetes Mellitus, Type 2

United Kingdom
Fulcrum Therapeutics

Terminated

Losmapimod Safety and Efficacy in COVID-19 (LOSVID)

COVID-19

United States, Mexico, Brazil, Peru
EicOsis Human Health Inc.

Completed

Safety, Tolerability, Pharmacokinetics and Food Effects of Oral EC5026 in Healthy Subjects

Healthy Adults

United States
Harmony Biosciences, LLC

Active, not recruiting

A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension

Prader-Willi Syndrome

United States
Brigham and Women's Hospital

Enrolling by invitation

DAW2020 on OSA Endotypic Traits (SedOSA)

Obstructive Sleep Apnea (OSA)

United States
EicOsis Human Health Inc.
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Safety, Tolerability, and Pharmacokinetics of Oral EC5026 in Healthy Subjects

Healthy Adults

United States
Brigham and Women's Hospital

Completed

DAW1033B2 in Obstructive Sleep Apnea (OsaStimB2)

Obstructive Sleep Apnea (OSA)

United States
University of Exeter

Completed

The Impact of Enteral Versus Oral Protein Feeding on Muscle Protein Synthesis in Healthy Young Males and Females

Healthy

United Kingdom
Spero Therapeutics
Simbec Research

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Crinetics Pharmaceuticals Inc.

Completed

A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult Volunteers

Healthy Volunteers

Australia
Giselle Sholler
Beat NB Cancer Foundation; Because of Ezra; K C Pharmaceuticals Inc.

Completed

Preventative Trial of Difluoromethylornithine (DFMO) in High Risk Patients With Neuroblastoma That is in Remission

Neuroblastoma

United States
Cancer Prevention Pharmaceuticals, Inc.

Completed

Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis

United States, Belgium, Germany, Canada, Netherlands, Spain, United Kingdom

Search clinical trials for: oral eflornithine placebo

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