Search clinical trials for: rhIGF-1

Total 14198 results

Insmed Incorporated

Terminated

Research Study Using Recombinant Human Insulin-Like Growth Factor-1/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 for Children With Noonan Syndrome

Noonan Syndrome

United States
Dompé Farmaceutici S.p.A

Recruiting

A Study to Evaluate Safety and Efficacy of a New Formulation of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution in Patients With Dry Eye Disease (REDUCO)

Dry Eye Disease

United States, Italy
Boston Children's Hospital
Autism Speaks; International Rett Syndrome Foundation

Completed

Treatment of Rett Syndrome With rhIGF-1 (Mecasermin [rDNA]Injection)

Rett Syndrome

United States
Children's Hospital Medical Center, Cincinnati

Completed

IGF-1 Treatment for Individuals With Short Stature Due to PAPP-A2 Deficiency

Short Stature
Ipsen

Completed

Prepubertal Children With Growth Failure Associated With Primary Insulin-Like Growth Factor-1 (IGF-1) Deficiency

Growth Disorders | Insulin-Like Growth Factor-1 Deficiency

United States
Dompé Farmaceutici S.p.A
Covance

Completed

Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers (NGF0112)

Healthy

Switzerland, United Kingdom
Massachusetts General Hospital
Tercica

Completed

Safety Profile of Insulin Like Growth Factor-1 (IGF-I) Administration in Adolescents

Anorexia Nervosa

United States
Shire

Completed

Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP) (PEDAL)

Retinopathy of Prematurity (ROP)

United States, Italy, Netherlands, Poland, Sweden, United Kingdom
National Institute of Neurological Disorders and...

Completed

A 48-Week (24-Week Baseline Followed by a 24-Week Treatment) Phase II Pilot Study of the Tolerability and Effect/Efficacy of Subcutaneously Administered Insulin-Like Growth Factor-1 (rhIGF) (CEP-151) in Multiple Sclerosis (MS) Patients

Multiple Sclerosis

United States
Insmed Incorporated

Completed

IGF-I/IGFBP-3 Therapy in Children and Adolescents With Growth Hormone Insenitivity Syndrome (GHIS) Such as Laron Syndrome

Laron Syndrome | Growth Hormone Insensitivity Syndrome (GHIS)

United States, Argentina, Australia, Brazil, China, Egypt, Germany, Israel, Italy, Norway, Peru, Slovakia, Turkey, United Kingdom
University College Cork

Completed

Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack (RESUS-AMI)

Myocardial Infarction | Heart Failure

Ireland, Netherlands
Ipsen

Completed

Recombinant Human Insulin-Like Growth Factor (rhIGF-1) Treatment of Short Stature Associated With IGF-1 Deficiency

Growth Disorders | Insulin-Like Growth Factor-1 Deficiency

United States
Dompé Farmaceutici S.p.A
Cross Research S.A.

Completed

Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye

Dry Eye Syndrome

Austria
Insmed Incorporated
Muscular Dystrophy Association

Completed

Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1

Myotonic Dystrophy Type 1

United States
Daewoong Pharmaceutical Co. LTD.

Unknown

The Clinical Study for Evaluation of Efficacy and Safety of EGF on Oral Mucositis in Radiation Therapy Patients

Stomatitis

Korea, Republic of
Daewoong Bio Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of rhEGF Eye Drops in Healthy Male Subjects

Dry Eye Syndromes

Korea, Republic of
The Catholic University of Korea

Unknown

Preventive Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors

Drug-Related Side Effects and Adverse Reactions | Epidermal Growth Factor

Korea, Republic of
Nationwide Children's Hospital
Tercica

Terminated

Effect of Increlex® on Children With Crohn Disease

Crohn Disease

United States
Massachusetts General Hospital

Completed

Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa (814)

Disorder of Bone Density and Structure, Unspecified

United States
Dompé Farmaceutici S.p.A

Completed

A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye

Dry Eye Syndrome

United States
The Catholic University of Korea

Unknown

Therapeutic Effect of EGF Cream for Cutaneous Adverse Event of EGFR Inhibitors

Drug-Related Side Effects and Adverse Reactions | Epidermal Growth Factor

Korea, Republic of
Boston Children's Hospital
International Rett Syndrome Foundation

Completed

Treatment of Rett Syndrome With Recombinant Human IGF-1

Rett Syndrome

United States
PT. Daewoong Infion
Equilab International

Completed

Efficacy and Safety Evaluation of EASYEF® in Acute Wound (Split-thickness Skin Graft Donor Site)

Skin Graft Scar | Split-Thickness Skin Graft (STSG)

Indonesia
Ipsen

Terminated

rhGH and rhIGF-1 Combination Therapy in Children With Short Stature Associated With IGF-1 Deficiency

Insulin-like Growth Factor-1 Deficiency

United States
Dompé Farmaceutici S.p.A

Completed

Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis. (REPARO)

Keratitis | Neurotrophic Keratitis | Corneal Ulcer

Germany, Italy, France, Poland, Spain, United Kingdom
Dompé Farmaceutici S.p.A

Completed

A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery

Ocular Discomfort

Italy
Dompé Farmaceutici S.p.A
Cromsource

Completed

Study to Evaluate Safety and Efficacy of rhNGF Eye Drops Solution Versus Vehicle in Patients With Glaucoma (NGF-Glaucoma)

Glaucoma

United States
Daewoong Pharmaceutical Co. LTD.

Completed

Efficacy and Safety of rhEGF in Diabetic Foot Ulcer Patients With Uncontrolled Diabetic Mellitus

Diabetic Foot Ulcer Patients With Uncontrolled Diabetes Mellitus

Korea, Republic of
Massachusetts General Hospital

Completed

IGF-1 and Bone Loss in Women With Anorexia Nervosa

Anorexia Nervosa | Osteoporosis | Osteopenia

United States
Aga Khan University
The Hospital for Sick Children; Grand Challenges Canada

Completed

The Prevention of Rh Disease of Newborns in Pakistan

Rhesus Disease | Anti-D (Rh) Antibodies Affecting Care of Mother

Pakistan
Dompé Farmaceutici S.p.A
Cromsource

Completed

Study to Evaluate Safety, Tolerability & PK of rhNGF in Healthy Volunteers

Healthy Volunteers

United States
SVS Institute of Dental Sciences

Unknown

RhEGF Incorporated in An Absorbable Collagen Membrane for The Management Of Gingival Recession Defects

Periodontitis

India
Dompé Farmaceutici S.p.A

Completed

Evaluation of Efficacy of 20 µg/ml rhNGF New Formulation (With Anti-oxidant) in Patients With Stage 2 and 3 NK

Neurotrophic Keratitis

United States
Shire

Completed

IGF-1/IGFBP3 Prevention of Retinopathy of Prematurity

Retinopathy of Prematurity (ROP)

United States, Italy, Netherlands, United Kingdom, Sweden, Poland
EMD Serono Research & Development Institute, Inc.
Nordic Bioscience A/S

Completed

A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee (FORWARD)

Osteoarthritis, Knee

Estonia, Romania, Hong Kong, Czechia, Denmark, Poland, Argentina, United States
University Hospital Southampton NHS Foundation...

Completed

A Study to Assess Safety and Efficacy of a Novel Treatment, Keratinocyte Growth Factor (KGF), in Asthmatic Patients

Bronchial Asthma

United Kingdom
Dompé Farmaceutici S.p.A

Completed

A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP) (Lumos)

Retinitis Pigmentosa

Italy
Merck KGaA, Darmstadt, Germany

Completed

A Multicenter Study of rhFGF 18 in Patients With Knee Osteoarthritis Not Requiring Surgery

Knee Osteoarthritis

Germany, Croatia, Bulgaria, Canada, Finland, Poland, Serbia, South Africa, Sweden
The Immunobiological Technology Institute (Bio-Manguinhos)...

Active, not recruiting

Efficacy and Safety Evaluation of the Intralesional Recombinant Human Epidermal Growth Factor (rhEGF) in Subjects With Diabetic Foot Ulcer.

Foot Ulcer, Diabetic | Epidermal Growth Factor
Ospedale San Raffaele
Dompé Farmaceutici S.p.A

Completed

Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema (NEMO)

Retinitis Pigmentosa | Cystoid Macular Edema

Italy
G. d'Annunzio University

Completed

An 8-week Follow-up to Evaluate the Renewal of Corneal Nerves Structure and Function in Patients With Neurotrophic Keratopathy Treated With Recombinant Human Nerve Growth Factor (rhNGF) Eyedrops

Neurotrophic Keratopathy

Italy
University of Sao Paulo General Hospital

Completed

Comparison of Two Application Regimens for Viscosupplementation

Osteoarthritis

Brazil
Orasis Pharmaceuticals Ltd.

Completed

A Multi-Center, Double-Masked Evaluation of the Efficacy and Safety of CSF-1 in the Treatment of Presbyopia

Presbyopia

United States
University of Thessaly

Completed

Recovery Kinetics After Speed-Εndurance Maintenance Training

Muscle Damage

Greece
Chulalongkorn University

Completed

Acute Effect of High Intensity Interval Exercise in Patients With Allergic Rhinitis

Allergic Rhinitis

Thailand
Massachusetts General Hospital

Completed

Effects of Anorexia Nervosa on Peak Bone Mass

Anorexia Nervosa

United States
University of Sao Paulo General Hospital

Completed

Comparison of Posterior Tibial Nerve Electrical Stimulation Protocols for Overactive Bladder Syndrome

Overactive Bladder Syndrome

Brazil
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal; Royal Victoria Hospital, Canada; Queen Elizabeth II Health Sciences Centre and other collaborators

Completed

A Study to Evaluate the Lipid Regulating Effects of 1-Methylnicotinamide (1-MNA)

Hypertriglyceridemia

Canada
The University of Texas Health Science Center,...
National Heart, Lung, and Blood Institute (NHLBI); United States Department... and other collaborators

Completed

Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR)

Trauma

United States, Canada
Yonsei University

Completed

Effects of 1:1 Inspiratory to Expiratory Ratios on Oxygenation and Intrapulmonary Shunt Fraction During One Lung Ventilation in the Obese Patients

Obese Patients, One Lung Ventilation

Korea, Republic of

Search clinical trials for: rhIGF-1

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