Search clinical trials for: rhIGF-1 (mecasermin) for a period of 86 weeks

Total 230 results

Ipsen

Completed

Recombinant Human Insulin-Like Growth Factor (rhIGF-1) Treatment of Short Stature Associated With IGF-1 Deficiency

Growth Disorders | Insulin-Like Growth Factor-1 Deficiency

United States
Boston Children's Hospital
Autism Speaks; International Rett Syndrome Foundation

Completed

Treatment of Rett Syndrome With rhIGF-1 (Mecasermin [rDNA]Injection)

Rett Syndrome

United States
Ipsen

Completed

Prepubertal Children With Growth Failure Associated With Primary Insulin-Like Growth Factor-1 (IGF-1) Deficiency

Growth Disorders | Insulin-Like Growth Factor-1 Deficiency

United States
Shire

Completed

Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP) (PEDAL)

Retinopathy of Prematurity (ROP)

United States, Italy, Netherlands, Poland, Sweden, United Kingdom
University College Cork

Completed

Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack (RESUS-AMI)

Myocardial Infarction | Heart Failure

Ireland, Netherlands
Marmara University

Not yet recruiting

Oral Motor Intervention to Preterms by Their Mothers

Premature

Turkey
Children's Hospital Medical Center, Cincinnati

Completed

IGF-1 Treatment for Individuals With Short Stature Due to PAPP-A2 Deficiency

Short Stature
National Institute of Neurological Disorders and...

Completed

A 48-Week (24-Week Baseline Followed by a 24-Week Treatment) Phase II Pilot Study of the Tolerability and Effect/Efficacy of Subcutaneously Administered Insulin-Like Growth Factor-1 (rhIGF) (CEP-151) in Multiple Sclerosis (MS) Patients

Multiple Sclerosis

United States
Massachusetts General Hospital
Tercica

Completed

Safety Profile of Insulin Like Growth Factor-1 (IGF-I) Administration in Adolescents

Anorexia Nervosa

United States
University of Roma La Sapienza

Unknown

Potential Impact of Cigarette Smoking on Platelet Reactivity in Patients on Dual Antiplatelet Therapy With P2Y12 Inhibitors (COPTER)

Coronary Artery Disease

Italy
Ipsen

Terminated

rhGH and rhIGF-1 Combination Therapy in Children With Short Stature Associated With IGF-1 Deficiency

Insulin-like Growth Factor-1 Deficiency

United States
Boston Children's Hospital
International Rett Syndrome Foundation

Completed

Treatment of Rett Syndrome With Recombinant Human IGF-1

Rett Syndrome

United States
Hospital de Clinicas de Porto Alegre

Unknown

Iron Supplementation in Heart Failure Patients With Anemia: The IRON-HF Study

Heart Failure | Anemia

Brazil
Dompé Farmaceutici S.p.A
Covance

Completed

Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers (NGF0112)

Healthy

Switzerland, United Kingdom
Hôpital Rothschild

Completed

Serious Games for Training in Oral Rehabilitation (Playdent)

Health Knowledge, Attitudes, Practice

France
University of Vigo

Unknown

Multicomponent Program on a Group of Nonagenarians (ELTGN)

Quality of Life | Healthy | Physical Activity | Aging

Spain
Cairo University

Recruiting

Efficacy Of Muscle Energy Technique On Shoulder Adhesive Capsulitis Post Mastectomy

Adhesive Capsulitis of Shoulder

Egypt
Massachusetts General Hospital

Completed

Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa (814)

Disorder of Bone Density and Structure, Unspecified

United States
Second Affiliated Hospital, School of Medicine,...
Tongji Hospital; Qilu Hospital of Shandong University; First Hospital of China... and other collaborators

Recruiting

A Study With Pembrolizumab for Non-small Cell Lung Cancer (NSCLC)

Pembrolizumab | Non-small-lung-cell Cancer, NSCLC

China
University of Southern California

Not yet recruiting

Role of ChatGPT in Vestibular Schwannoma Management

Vestibular Schwannoma
University of Aarhus

Completed

Biomarkers in Urine for Children With Monosymptomatic Nocturnal Enuresis and Nocturnal Polyuria

Nocturnal Enuresis

Denmark
Xspray Pharma AB

Completed

Evaluating the Pharmacokinetic Parameters and Relative Bioavailability of Sorafenib (XS005) in Healthy Male Subjects

Pharmacokinetics | Bioavailability

United Kingdom
Escola Superior de Tecnologia da Saúde do Porto

Completed

Immediate and Long-term Effects of an Adaptation of the "Balloon-blowing Exercise"

Healthy

Portugal
Universiti Putra Malaysia

Completed

Effect of Core Strength Training on Wushu C-level Difficulty Movements ,12 Weeks of Core Strength Training

Experimental Myasthenia

China
Dompé Farmaceutici S.p.A
Cross Research S.A.

Completed

Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye

Dry Eye Syndrome

Austria
University Hospital, Rouen

Not yet recruiting

Efficacy of Glutamine Supplementation in Patients Suffering From Irritable Bowel Syndrome With Impaired Intestinal Permeability (MISSISIIPI)

Irritable Bowel Syndrome
University of Ioannina

Completed

Body Weight Supported Treadmill Training as Physical Therapy Treatment to Spinal Cord Injury Patients

Spinal Cord Injury/Damage

Greece
Massachusetts General Hospital

Completed

Does Vitamin C Reduce Finger Stiffness After Distal Radius Fractures?

Distal Radius Fracture | Finger Stiffness

United States
Praxis Precision Medicines

Recruiting

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE) (EMBOLD)

SCN2A Encephalopathy | SCN8A Encephalopathy

United States, Spain
University of Roma La Sapienza

Completed

The Role of Extracorporeal Shock Wave Therapy in the Treatment of Trapezial-Metacarpal Osteoarthritis. A Double Blind Randomized Controlled Study.

Osteoarthritis Trapezial-metacarpal Joint

Italy
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.

Completed

Low Dose Daily Erlotinib in Combination With High Dose Twice Weekly Erlotinib in Patients With EGFR-Mutant Lung Cancer

EGFR-Mutant Lung Cancer

United States
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Recruiting

Development of a Clinical Screening, Diagnostic and Evaluation Tool for Patients With Lower Limb Lymphedema: Aim 1 (EvaLymph-Leg1)

Lower Limb Lymphedema

Belgium
Hospices Civils de Lyon

Terminated

Digital Cognitive Remote Training in Alzheimer's Disease (MA-EIAD) (DCRT-AD)

Alzheimer Disease

France
Umm Al-Qura University

Completed

Alter-G Training on Gait and Balance in Diabetic Neuropathy Patients

Diabetic Peripheral Neuropathy

Saudi Arabia
Indiana University
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Erenumab-aooe in Patients With Temporomandibular Disorder

Temporomandibular Disorder

United States
Massachusetts General Hospital

Completed

Effects of Anorexia Nervosa on Peak Bone Mass

Anorexia Nervosa

United States
Technical University of Munich

Completed

Detection of CF-DNA in Patients With Gastrointestinal Stromal Tumors (GIST)

Gastrointestinal Stromal Tumors

Germany
Zhenzhen Liu

Recruiting

Comparing Level 1 Compression Sleeves With Routine Care in Preventing Breast Cancer-related Arm Lymphedema

Breast Cancer-related Arm Lymphedema

China
Rabin Medical Center
Tel Aviv University; The Leona M. and Harry B. Helmsley Charitable Trust

Recruiting

Biomarker-based Multidisciplinary Team (Bio-MDT) Approach to Personalized Microbial-targeted Treatment of Pouchitis and Crohn's Disease (Bio-MDT)

Inflammatory Bowel Diseases

Israel
Dompé Farmaceutici S.p.A

Completed

Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis. (REPARO)

Keratitis | Neurotrophic Keratitis | Corneal Ulcer

Germany, Italy, France, Poland, Spain, United Kingdom
University Hospital Center of Martinique
National Cancer Institute, France; GIRCI SOHO; Laboratoire de Psychologie des... and other collaborators

Recruiting

Innovative Cognitive and Behavioral Psychotherapy for Cocaine Use Disorder (PICOC)

Cocaine Use Disorder

Martinique
Merck Sharp & Dohme LLC

Terminated

A Study of the Efficacy and Safety of MK2578 for the Treatment of Anemia in Patients With Kidney Disease (MK2578-003-AM03-EXT12)

Anemia | Chronic Kidney Disease
Affiliated Hospital of Nantong University

Recruiting

PD-1 Inhibitor Combined With Radiotherapy for Elderly ESCC

Esophageal Squamous Cell Carcinoma

China
Jiuda Zhao
Second Hospital of Lanzhou University

Recruiting

A Study to Evaluate the Efficacy and Safety of Sintilimab Plus Apatinib and Chemotherapy in Patients With HER-2 Negative Microsatellite Stability (MSS) Advanced or Metastatic Gastric (GC) or Gastroesophageal Junction (GEJ) Cancer

Gastric Cancer | Chemotherapy | Immunotherapy

China
Aarhus University Hospital

Unknown

The Effect of Acute and Chronic Exercise at the Metabolic Syndrome and Markers of Inflammation in Obese Subjects

Healthy | Obesity

Denmark
University of Kassel
International Psychoanalytic University Berlin; Deutsche Gesellschaft für Katathym...

Recruiting

Differential Efficacy of Guided Imagery Psychotherapy: Non-Inferiority Trial and Exploration of Differential Indication (DE-GIP)

Emotional Disorders

Germany
Assistance Publique - Hôpitaux de Paris

Recruiting

Diagnostic Value of sFlt-1/PlGF Ratio for the Etiology of Intra Uterine Growth Restriction - ANGIOPAG (ANGIOPAG)

Intrauterine Growth Restriction | Fetal Growth Restriction (FGR)

France
LiuYing

Not yet recruiting

Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer (MSI-H/dMMR)

Colorectal Cancer | Neoadjuvant Therapy | Mismatch Repair-deficient (dMMR) | Microsatellite Instability-high (MSI-H)

China
Universidade Estadual de Maringá

Unknown

Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder (NACBD)

Bipolar Disorder

Brazil
Taipei Medical University WanFang Hospital

Unknown

The Synergistic Effects of Intra-articular Hyaluronic Acid and Platelet-rich Plasma Injections on Knee Osteoarthritis (HAPRP)

Osteoarthritis Knees Both

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